CL2020002755A1 - Ácidos nucleicos recombinantes que codifican una o más proteínas cosméticas para usos estéticos. - Google Patents

Ácidos nucleicos recombinantes que codifican una o más proteínas cosméticas para usos estéticos.

Info

Publication number
CL2020002755A1
CL2020002755A1 CL2020002755A CL2020002755A CL2020002755A1 CL 2020002755 A1 CL2020002755 A1 CL 2020002755A1 CL 2020002755 A CL2020002755 A CL 2020002755A CL 2020002755 A CL2020002755 A CL 2020002755A CL 2020002755 A1 CL2020002755 A1 CL 2020002755A1
Authority
CL
Chile
Prior art keywords
nucleic acids
encode
recombinant nucleic
proteins
cosmetic proteins
Prior art date
Application number
CL2020002755A
Other languages
English (en)
Inventor
Suma Krishnan
Pooja Agarwal
Trevor Parry
Original Assignee
Krystal Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Krystal Biotech Inc filed Critical Krystal Biotech Inc
Publication of CL2020002755A1 publication Critical patent/CL2020002755A1/es

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A61K35/763—Herpes virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/86—Products or compounds obtained by genetic engineering
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/91—Injection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16041—Use of virus, viral particle or viral elements as a vector
    • C12N2710/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16621—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16631—Uses of virus other than therapeutic or vaccine, e.g. disinfectant

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)

Abstract

La presente descripción proporciona ácidos nucleicos recombinantes que comprenden uno o más polinucleótidos que codifican una o más proteínas cosméticas (por ejemplo, una o más proteínas de colágeno humanas); virus que comprenden los ácidos nucleicos recombinantes; composiciones (por ejemplo, formulaciones cosméticas) que comprenden los virus y/o ácidos nucleicos recombinantes; métodos para utilizarlos; y productos de elaboración o kits de estos.
CL2020002755A 2018-04-27 2020-10-23 Ácidos nucleicos recombinantes que codifican una o más proteínas cosméticas para usos estéticos. CL2020002755A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862663476P 2018-04-27 2018-04-27

Publications (1)

Publication Number Publication Date
CL2020002755A1 true CL2020002755A1 (es) 2021-01-29

Family

ID=68291937

Family Applications (5)

Application Number Title Priority Date Filing Date
CL2020002755A CL2020002755A1 (es) 2018-04-27 2020-10-23 Ácidos nucleicos recombinantes que codifican una o más proteínas cosméticas para usos estéticos.
CL2023001338A CL2023001338A1 (es) 2018-04-27 2023-05-09 Ácidos nucleicos recombinantes que codifican una o más proteínas cosméticas para usos estéticos.
CL2024000410A CL2024000410A1 (es) 2018-04-27 2024-02-09 Ácidos nucleicos recombinantes que codifican una o más proteínas cosméticas para usos estéticos.
CL2024000411A CL2024000411A1 (es) 2018-04-27 2024-02-09 Ácidos nucleicos recombinantes que codifican una o más proteínas cosméticas para usos estéticos.
CL2024000409A CL2024000409A1 (es) 2018-04-27 2024-02-09 Ácidos nucleicos recombinantes que codifican una o más proteínas cosméticas para usos estéticos.

Family Applications After (4)

Application Number Title Priority Date Filing Date
CL2023001338A CL2023001338A1 (es) 2018-04-27 2023-05-09 Ácidos nucleicos recombinantes que codifican una o más proteínas cosméticas para usos estéticos.
CL2024000410A CL2024000410A1 (es) 2018-04-27 2024-02-09 Ácidos nucleicos recombinantes que codifican una o más proteínas cosméticas para usos estéticos.
CL2024000411A CL2024000411A1 (es) 2018-04-27 2024-02-09 Ácidos nucleicos recombinantes que codifican una o más proteínas cosméticas para usos estéticos.
CL2024000409A CL2024000409A1 (es) 2018-04-27 2024-02-09 Ácidos nucleicos recombinantes que codifican una o más proteínas cosméticas para usos estéticos.

Country Status (14)

Country Link
US (3) US10786438B2 (es)
EP (1) EP3810149A4 (es)
JP (4) JP7602999B2 (es)
KR (1) KR20210005141A (es)
CN (4) CN119523872A (es)
AU (2) AU2019260757B2 (es)
BR (1) BR112020021804A2 (es)
CA (1) CA3095187A1 (es)
CL (5) CL2020002755A1 (es)
CO (1) CO2020013588A2 (es)
MX (1) MX2020011257A (es)
SG (1) SG11202009895TA (es)
WO (1) WO2019210219A1 (es)
ZA (2) ZA202306237B (es)

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CN117143223B (zh) * 2022-08-23 2024-03-08 山西锦波生物医药股份有限公司 一种生物合成人体结构性材料的制备方法
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CN117402235B (zh) * 2023-10-25 2024-06-11 山西锦波生物医药股份有限公司 生物合成人体结构性材料iv型胶原蛋白的制备方法
CN120060268A (zh) * 2023-11-29 2025-05-30 深圳瑞吉生物科技有限公司 一种mRNA分子及其在制备美容护肤产品中的应用
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CN118324899B (zh) * 2024-06-13 2024-08-20 江苏亨瑞生物医药科技有限公司 一种重组xvii型人源化胶原蛋白、制备方法及其应用
CN118530338B (zh) * 2024-06-17 2025-06-10 西安巨子生物基因技术股份有限公司 具有促毛囊生长作用的重组人xvii型胶原蛋白及其应用
CN118388666B (zh) * 2024-06-25 2024-09-20 山东美瑞生物技术有限公司 一种促进皮肤胶原蛋白和弹性蛋白再生的多肽及制备方法
CN118480554B (zh) * 2024-07-16 2024-10-18 苏州拾光医药生物科技有限公司 重组弹性蛋白及其表达体系和应用
CN119264242A (zh) * 2024-10-11 2025-01-07 常州泰美瑞生物科技有限公司 一种重组xvii型胶原蛋白及其制备方法和应用
CN118949130B (zh) * 2024-10-18 2025-10-03 浙江清华长三角研究院 一种面部填充用胶原蛋白材料
CN119371518A (zh) * 2024-12-30 2025-01-28 冠图生物科技(潍坊)有限公司 一种高稳定重组人源化弹性蛋白、表达该蛋白的基因工程菌及其应用
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CN119591670B (zh) * 2025-01-20 2025-12-16 昆明理工大学 一种马乳源小分子肽及其应用

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