CL2024001482A1 - Péptido con afinidad por el receptor de transferrina humana - Google Patents

Péptido con afinidad por el receptor de transferrina humana

Info

Publication number
CL2024001482A1
CL2024001482A1 CL2024001482A CL2024001482A CL2024001482A1 CL 2024001482 A1 CL2024001482 A1 CL 2024001482A1 CL 2024001482 A CL2024001482 A CL 2024001482A CL 2024001482 A CL2024001482 A CL 2024001482A CL 2024001482 A1 CL2024001482 A1 CL 2024001482A1
Authority
CL
Chile
Prior art keywords
peptide
affinity
transferrin receptor
human transferrin
compound
Prior art date
Application number
CL2024001482A
Other languages
English (en)
Inventor
Onouchi Takashi
Takahashi Kenichi
Original Assignee
Japan Chem Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Chem Res filed Critical Japan Chem Res
Publication of CL2024001482A1 publication Critical patent/CL2024001482A1/es

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Abstract

En una realización, la presente invención se refiere a un péptido con afinidad por el receptor de transferrina humana, el que se puede usar para que se una a cualquiera compuesto (una proteína, un ácido nucleico, un compuesto de bajo peso molecular y compuestos similares) que debería funcionar en el sistema nervioso central (SNC), de modo de permitir que este compuesto atraviese la barrera hematoencefálica, y se refiere al uso del péptido. El péptido es, por ejemplo, un péptido que tiene la secuencia de aminoácidos seleccionada del grupo que consiste en las secuencias de aminoácidos presentadas en las SEQ ID NOS: 3 a 7 y 55, o una mutante de las mismas.
CL2024001482A 2021-11-19 2024-05-16 Péptido con afinidad por el receptor de transferrina humana CL2024001482A1 (es)

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TW202436352A (zh) * 2023-02-07 2024-09-16 日商Ｊｃｒ製藥股份有限公司 人類運鐵蛋白受體親和性肽
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DE69435126D1 (de) 1993-10-19 2008-10-02 Scripps Research Inst Synthetische humane neutralisierende monoklonale antikörper gegen hiv
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WO2008022349A2 (en) 2006-08-18 2008-02-21 Armagen Technologies, Inc. Agents for blood-brain barrier delivery
AU2008282496B2 (en) 2007-07-27 2013-04-04 Armagen Technologies, Inc. Methods and compositions for increasing alpha-iduronidase activity in the CNS
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