CL2024002285A1 - Procesos para la preparación de alfa-hidroxi ésteres por esterificación de alfa-hidroxiácidos - Google Patents

Procesos para la preparación de alfa-hidroxi ésteres por esterificación de alfa-hidroxiácidos

Info

Publication number
CL2024002285A1
CL2024002285A1 CL2024002285A CL2024002285A CL2024002285A1 CL 2024002285 A1 CL2024002285 A1 CL 2024002285A1 CL 2024002285 A CL2024002285 A CL 2024002285A CL 2024002285 A CL2024002285 A CL 2024002285A CL 2024002285 A1 CL2024002285 A1 CL 2024002285A1
Authority
CL
Chile
Prior art keywords
alpha
hydroxy
processes
esterification
preparation
Prior art date
Application number
CL2024002285A
Other languages
English (en)
Inventor
Huang Shengshu
Li Fangyi
Xu Li
Nuyens Filip
Lao Ye
Salaklang Jatuporn
Tang Zhuo
Original Assignee
Kemin Ind Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kemin Ind Inc filed Critical Kemin Ind Inc
Publication of CL2024002285A1 publication Critical patent/CL2024002285A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/105—Aliphatic or alicyclic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/10—Feeding-stuffs specially adapted for particular animals for ruminants
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/10—Feeding-stuffs specially adapted for particular animals for ruminants
    • A23K50/15—Feeding-stuffs specially adapted for particular animals for ruminants containing substances which are metabolically converted to proteins, e.g. ammonium salts or urea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/26—Separation; Purification; Stabilisation; Use of additives
    • C07C319/28—Separation; Purification
    • C07C319/30—Separation; Purification from the by-products of refining mineral oils
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/02—Preparation of carboxylic acid esters by interreacting ester groups, i.e. transesterification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Birds (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fodder In General (AREA)

Abstract

La presente divulgación proporciona procesos para preparar un alfa-hidroxi éster a partir del alfa-hidroxiácido correspondiente mediante transesterificación. También se proporcionan alfa-hidroxi ésteres preparados de acuerdo con los procesos divulgados en el presente documento y composiciones que comprenden los alfa-hidroxi ésteres.
CL2024002285A 2019-09-06 2024-07-29 Procesos para la preparación de alfa-hidroxi ésteres por esterificación de alfa-hidroxiácidos CL2024002285A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2019104692 2019-09-06

Publications (1)

Publication Number Publication Date
CL2024002285A1 true CL2024002285A1 (es) 2024-12-27

Family

ID=74852116

Family Applications (3)

Application Number Title Priority Date Filing Date
CL2022000516A CL2022000516A1 (es) 2019-09-06 2022-03-02 Procesos para la preparación de alfa-hidroxi ésteres por esterificación de alfa-hidroxiácidos.
CL2024002285A CL2024002285A1 (es) 2019-09-06 2024-07-29 Procesos para la preparación de alfa-hidroxi ésteres por esterificación de alfa-hidroxiácidos
CL2024002284A CL2024002284A1 (es) 2019-09-06 2024-07-29 Procesos para la preparación de alfa-hidroxi ésteres por esterificación de alfa-hidroxiácidos

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CL2022000516A CL2022000516A1 (es) 2019-09-06 2022-03-02 Procesos para la preparación de alfa-hidroxi ésteres por esterificación de alfa-hidroxiácidos.

Family Applications After (1)

Application Number Title Priority Date Filing Date
CL2024002284A CL2024002284A1 (es) 2019-09-06 2024-07-29 Procesos para la preparación de alfa-hidroxi ésteres por esterificación de alfa-hidroxiácidos

Country Status (11)

Country Link
US (2) US20220332681A1 (es)
EP (1) EP4025561A4 (es)
JP (2) JP7765382B2 (es)
KR (1) KR20220057525A (es)
CN (2) CN121318803A (es)
AU (1) AU2020343325A1 (es)
CA (1) CA3150773A1 (es)
CL (3) CL2022000516A1 (es)
CO (1) CO2022003063A2 (es)
MX (1) MX2022002512A (es)
WO (1) WO2021046234A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2022006103A (es) * 2019-11-22 2022-07-19 Kemin Ind Inc Procesos para la preparación de alfa-hidroxiésteres mediante reacciones de acoplamiento de grignard y tiolación.
KR102829625B1 (ko) * 2022-03-29 2025-07-04 한국바이오켐제약 주식회사 페노피브릭산의 정제방법 및 이에 의해 제조된 페노피브레이트

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4874877A (en) * 1988-04-19 1989-10-17 Pfizer Inc. Process for optically active 3-(methane-sulfonyloxy)thiolane and analogs
JPH06316557A (ja) * 1993-03-06 1994-11-15 Fuji Kagaku Kogyo Kk アルキルチオ脂肪酸誘導体、製造法及びその肝臓疾患、腎臓疾患、膵臓疾患及び脳疾患用剤
FR2785773B1 (fr) * 1998-11-13 2001-04-20 Rhone Poulenc Nutrition Animal Utilisation d'esters de methionine en nutrition animale
FR2791673B1 (fr) * 1999-04-02 2001-06-08 Rhone Poulenc Animal Nutrition Procede de preparation des esters de l'acide hydroxymethylthiobutyrique
WO2001058864A1 (en) * 2000-02-07 2001-08-16 Rhone-Poulenc Animal Nutrition Process for the preparation of 2-hydroxy-4-methylthio butyric acid esters
US20060149090A1 (en) * 2002-02-19 2006-07-06 Mikio Watanabe Process for producing chain oligolactic acid ester
EP1888525A1 (en) * 2005-05-03 2008-02-20 Ranbaxy Laboratories Limited 3,6-disubstituted azabicyclo [3.1.0]hexane derivatives as muscarinic receptor antagonists
US8071805B2 (en) * 2006-07-21 2011-12-06 Sumitomo Chemical Company, Limited Process for producing 2-hydroxy-4-(methlthio)butyrate compounds and intermediates thereof
CN102093271A (zh) * 2011-01-25 2011-06-15 张维军 2-羟基-4-甲硫基丁酸烷基酯的制备方法
EP3461806B1 (en) * 2014-11-28 2020-08-05 Haldor Topsøe A/S Process for preparing alfa-hydroxy methionine analogues from sugars
BR112018075185A2 (pt) * 2016-06-24 2019-03-26 Novus International, Inc. formulações análogas de hidróxi metionina adequadas para aplicações de produtos químicos especializados
CN111825584B (zh) * 2020-07-30 2022-04-12 北京福元医药股份有限公司沧州分公司 一种消旋羟蛋氨酸钙的制备方法

Also Published As

Publication number Publication date
EP4025561A1 (en) 2022-07-13
CA3150773A1 (en) 2021-03-11
BR112022003547A2 (pt) 2022-05-17
CO2022003063A2 (es) 2022-04-19
CN114341107A (zh) 2022-04-12
EP4025561A4 (en) 2024-01-31
JP2025041771A (ja) 2025-03-26
US20220332681A1 (en) 2022-10-20
JP7765382B2 (ja) 2025-11-06
WO2021046234A1 (en) 2021-03-11
CN121318803A (zh) 2026-01-13
AU2020343325A1 (en) 2022-03-03
MX2022002512A (es) 2022-08-22
US20260001837A1 (en) 2026-01-01
KR20220057525A (ko) 2022-05-09
JP2022546018A (ja) 2022-11-02
CL2024002284A1 (es) 2024-12-27
CL2022000516A1 (es) 2022-10-07

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