CL2026000109A1 - Composiciones farmacéuticas de derivados de la insulina. - Google Patents
Composiciones farmacéuticas de derivados de la insulina.Info
- Publication number
- CL2026000109A1 CL2026000109A1 CL2026000109A CL2026000109A CL2026000109A1 CL 2026000109 A1 CL2026000109 A1 CL 2026000109A1 CL 2026000109 A CL2026000109 A CL 2026000109A CL 2026000109 A CL2026000109 A CL 2026000109A CL 2026000109 A1 CL2026000109 A1 CL 2026000109A1
- Authority
- CL
- Chile
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/545—Heterocyclic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Abstract
La presente invención se refiere a una composición que comprende un derivado de la insulina que comprende al menos un ácido arilborónico o arilboroxol; y metionina, así como también al uso de esta en el tratamiento de la diabetes, que incluye la diabetes de Tipo 1, la diabetes de Tipo 2.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP23186053 | 2023-07-18 | ||
| EP23195708 | 2023-09-06 | ||
| EP24162420 | 2024-03-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2026000109A1 true CL2026000109A1 (es) | 2026-03-27 |
Family
ID=91960593
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2026000109A CL2026000109A1 (es) | 2023-07-18 | 2026-01-13 | Composiciones farmacéuticas de derivados de la insulina. |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JP2025015465A (es) |
| KR (1) | KR20250015926A (es) |
| CN (1) | CN121532169A (es) |
| AR (1) | AR133270A1 (es) |
| AU (1) | AU2024295902A1 (es) |
| CL (1) | CL2026000109A1 (es) |
| CO (1) | CO2026000360A2 (es) |
| IL (1) | IL325789A (es) |
| MX (1) | MX2026000538A (es) |
| TW (1) | TW202504633A (es) |
| WO (1) | WO2025016992A1 (es) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2018002223A (es) * | 2015-08-25 | 2018-03-23 | Novo Nordisk As | Derivados de insulina novedosos y usos medicos de los mismos. |
| WO2019092125A1 (en) | 2017-11-09 | 2019-05-16 | Novo Nordisk A/S | Glucose-sensitive albumin-binding derivatives |
| EP3946363A2 (en) * | 2019-03-29 | 2022-02-09 | Novo Nordisk A/S | Glucose sensitive insulin derivatives |
| EP4126058A1 (en) | 2020-03-31 | 2023-02-08 | Protomer Technologies Inc. | Conjugates for selective responsiveness to vicinal diols |
| JP2024500284A (ja) | 2020-11-19 | 2024-01-09 | プロトマー・テクノロジーズ・インコーポレイテッド | 芳香族ホウ素含有化合物及びインスリン類似体 |
| WO2023225534A1 (en) | 2022-05-18 | 2023-11-23 | Protomer Technologies Inc. | Aromatic boron-containing compounds and related insulin analogs |
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2024
- 2024-07-16 AU AU2024295902A patent/AU2024295902A1/en active Pending
- 2024-07-16 JP JP2024113358A patent/JP2025015465A/ja active Pending
- 2024-07-16 WO PCT/EP2024/070073 patent/WO2025016992A1/en active Pending
- 2024-07-16 AR ARP240101849A patent/AR133270A1/es unknown
- 2024-07-16 TW TW113126537A patent/TW202504633A/zh unknown
- 2024-07-16 KR KR1020240093560A patent/KR20250015926A/ko active Pending
- 2024-07-16 CN CN202480047177.9A patent/CN121532169A/zh active Pending
- 2024-07-16 IL IL325789A patent/IL325789A/en unknown
-
2026
- 2026-01-13 CL CL2026000109A patent/CL2026000109A1/es unknown
- 2026-01-14 MX MX2026000538A patent/MX2026000538A/es unknown
- 2026-01-15 CO CONC2026/0000360A patent/CO2026000360A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2025016992A1 (en) | 2025-01-23 |
| JP2025015465A (ja) | 2025-01-30 |
| MX2026000538A (es) | 2026-03-02 |
| AR133270A1 (es) | 2025-09-10 |
| AU2024295902A1 (en) | 2026-01-15 |
| TW202504633A (zh) | 2025-02-01 |
| KR20250015926A (ko) | 2025-02-03 |
| CN121532169A (zh) | 2026-02-13 |
| IL325789A (en) | 2026-03-01 |
| CO2026000360A2 (es) | 2026-01-23 |