CN100352425C - Thin plaster, plaster thinning making method and apparatus - Google Patents

Thin plaster, plaster thinning making method and apparatus Download PDF

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Publication number
CN100352425C
CN100352425C CNB2006100201186A CN200610020118A CN100352425C CN 100352425 C CN100352425 C CN 100352425C CN B2006100201186 A CNB2006100201186 A CN B2006100201186A CN 200610020118 A CN200610020118 A CN 200610020118A CN 100352425 C CN100352425 C CN 100352425C
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plaster
thickness
cream base
thin
pressed
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CN1839798A (en
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莫有双
王增谊
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Abstract

The present invention relates to a thin black plaster which comprises a back lining material layer and a plaster layer attached to the back lining material layer, wherein the thickness of the plaster layer is from 0.1 to 0.9 mm. The present invention also relates to a producing method for the thin black plaster, which comprises the following steps: 1, decocted paste is made into a paste billet; 2, the obtained paste billet is pressed into a thin slice when being heated, and the thickness of the thin slice is kept between 0.1 mm and 0.9 mm; 3, the shaped slice-shaped black plaster is sheared, shaped and packaged. Thereby, a finished product is obtained. A thin black plaster producing apparatus comprises a conveying device whose front end is provided with a temperature control pelletizer for heating and thinning the paste, a billet shaping device for punching the paste pressed into the uniform thin slice into the round slice is arranged in the rear of the temperature control pelletizer, and a heating and thinning device capable of pressing the paste into the slice is arranged in the rear of the billet shaping device. The black plaster can be directly attached to the affected position without being heated and can be repeatedly taken off and attached for many times. The black plaster shaping machine has the advantages of simple structure and convenient operation and realizes the mechanized continuous production of shaping the black plaster.

Description

BAOZHI HEIGAOYAO, the thin system method of black plaster and the thin control equipment of black plaster
(1) technical field:
The present invention relates to a kind of Chinese medicine plaster---BAOZHI HEIGAOYAO; The invention still further relates to the thin system method of black plaster, and be the custom-designed production equipment of this method.
(2) background technology:
Existing medicine mostly is peroral dosage form greatly, and oral medicine is the digestion through stomach, the metabolism of liver, is finished by little intestinal absorption again.But after the destruction of medicine process liver detoxification and gastric acid, digestive enzyme, drug effect reduces greatly; And some oral medicine also can be not easy to patients with gastric disease and take the bigger stimulation of stomach generation; Some composition of some drugs accumulates on and is difficult in the body discharging, and takes medicine for a long time and can cause damage to health.Report according to interrelated data, United States Medicine circle is thought at 10~15 years from now on, / 3rd of an existing medicine can adopt Transdermal absorption, the advantage of releasing medicine through skin penetration system has been to remove the first pass effect of liver, avoided pharmaceutical chemistry and biological effect to stimulate, reduced the untoward reaction of human body, and medicine is to the infringement of gastrointestinal tract and liver etc. medicine for gastrointestinal, and patient uses also comparatively conveniently, goes wrong in patient's medication or uncomfortable reflection can in time be discontinued medication.At present the various plaster that generally use are the Transdermal absorption medicine, and commonly used have rubber plaster and a black plaster etc.Traditional black plaster is to refine into the creme of old tender appropriateness with Chinese crude drug, edible vegetable oil with Plumbum preparatium, removes behind the fire-toxin its manual stand is applied to mount on the backing material and makes.Traditional black plaster all is manual or half mechanically actuated, and efficient is low, and the processing cost height owing to there are a large amount of harmful gass to discharge in the manufacturing process, has bigger infringement to staff's health.In addition, because black plaster viscosity is extremely strong, and the temperature embrittlement that easily hardens when low, therefore be difficult to evenly, also very difficult it made thinner plaster layer stand with traditional method.So existing black ointment all more greatly, thicker, heavier, its weight generally between 10~30 grams, like this heavy neither portable band of plaster, also greatly improved the cost of plaster, particularly use the plaster of rare medicinal herbs, cost is higher, also causes the waste of drug resource simultaneously.Under topic before the guarantee pharmaceutical effectiveness is effective, cost saving again, traditional method is that black plaster is used repeatedly, this does not meet modern's health concept on the one hand, the modern generally is disposable use, paste and promptly abandoned afterwards in 1~2 day, can not surpass 5 days at most, and for traditional, not only big but also thick plaster, using still has a big chunk ointment not to be utilized after 5 days, abandon at this point, greatly wasted limited herb resource, on the other hand, made it softening before each the use because existing black plaster must heat, this heating repeatedly will be lost a large amount of volatile compositions in the plaster, causes drug effect to weaken.And owing to the very difficult weight of controlling plaster of traditional technology, so the weight error between each sheet plaster is bigger, does not meet the standardization idea of modern medicine, and preceding necessary heating of the each use of existing black plaster existence, use very inconvenient.These shortcomings make the modern consumer black ointment of more and more being unwilling to use, and therefore traditional black plaster has the trend that is replaced by rubber unguentum at present.Rubber unguentum mainly is to be that substrate and Chinese medical concrete are mixed and made into the stronger material of adhesivenesses such as rubber, polyisobutylene, such plaster quality is frivolous, the stickup better performances, when skin is taken off, plaster that can residual contamination skin, but erythema appears in skin easily, slight edema, and produce skin allergy, the adhesion of rubber unguentum is big more, easily more causes this inflammation; And the permeability of rubber unguentum is relatively poor, and the back skin of applying ointment or plaster is airtight not wet thoroughly, makes the outermost horny layer of skin surface very easily because of irriate causes hyperkeratosis, makes sweat gland mouth obturation then, hinders the drainage of perspiration; Perspiration is detained, and causes the skin dipping softening, makes whiteness of skin, deliquescing, also makes the tissue of skin become the good culture medium with suitable humiture simultaneously, and microorganisms such as antibacterial and fungus are bred easily at skin surface, cause antiperspirant pipe and follicular infection and eczema; Secondly the content of dispersion of rubber unguentum is few, and drug releasing rate is fast, and medicine continues release time and was generally 12 hours, does not reach the curative effect of healing.And the storage life of rubber unguentum only is 1 year, and the shelf-life of black ointment reaches 4~5 years.And the drug extract that is used to make rubber unguentum generally is to be extracting solution with water or alcohol, black ointment then is to be extracting solution with oil, therefore the effective ingredient of two kinds of ointment propositions is incomplete same, in addition as the Oleum Sesami of black ointment extracting solution, rapeseed oil, Oleum Verniciae fordii etc. itself have certain medicinal efficacy, for example Oleum Sesami has detoxifcation, anti-inflammatory effect, Plumbum preparatium itself also is the composition with curative effect in addition, it mainly has the effect of removing the necrotic tissue and promoting granulation, therefore black ointment has the specific drug effect that rubber unguentum does not have, and the lasting drug effect of black ointment when using is longer than rubber unguentum far away, make black plaster not replaced fully, and be worth developing by rubber unguentum or other plaster institute.
(3) summary of the invention:
The present invention will disclose that a kind of cost is low, and thickness is even, and is specious, easy to use, need not heat firmly to be affixed on the BAOZHI HEIGAOYAO in affected part; The present invention also will disclose the thin system method of this black plaster and be the custom-designed equipment of this method.
BAOZHI HEIGAOYAO of the present invention comprises back lining materials layer and plaster layer attached to it, the thickness of plaster layer is 0.1~0.9mm, in order to reach better effect, and can be with the THICKNESS CONTROL of plaster layer at 0.2~0.6mm, for reaching optimum efficiency, can be with the THICKNESS CONTROL of plaster layer at 0.3~0.5mm.Because the plaster layer makes very thin, when being affixed on the affected part, black plaster do not need to heat in advance, the only with hand centre of the palm is pressed in the affected part with plaster and gets final product, utilize body temperature can make the plaster layer securely with adhering skin, very convenient to use like this, equally also avoided black plaster being heated in advance and making its some active ingredient strengthen evaporable shortcoming, improved the drug effect of black plaster.And both made plaster layer system approached into 0.1~0.9mm scope, the performance drug effect that the content that still can guarantee the active ingredient of plaster layer is stable in the long time, continue, prove through applicant's repetition test, with the THICKNESS CONTROL of plaster layer at 0.1~0.2mm, the drug effect of black plaster can keep 12~24 hours, if at 0.2~0.9mm, its drug effect can keep 3~5 days even longer, can reach modern patient's pot life requirement fully with the THICKNESS CONTROL of plaster layer.Because BAOZHI HEIGAOYAO of the present invention is very thin, the ointment that needs seldom, diameter be the ointment of 3~8cm generally use creme weight within 2.5 grams, greatly provide cost savings.
Through applicant's repetition test, thickness, weight and the diameter of plaster layer are controlled in the above-mentioned scope, not only can guarantee the lasting in a long time performance drug effect that plaster can be stable, can also reduce Plumbum preparatium content in the plaster layer greatly, reduce drug toxicity, it is safer to allow the patient use, and can reduce production cost in addition, and the advantage of comparing the black plaster of selling in the market is self-evident.
It is laminar uniformly that described plaster layer preferably is thickness, and its edge is the thickness-tapered shape, can make plaster be affixed on the affected part more firmly like this.
BAOZHI HEIGAOYAO of the present invention can adopt following method to be prepared from, and this method step is:
1) creme is made the cream base; During preparation, after the creme of the fire-toxin of refining can being decorporated is poured into and makes the cream base in the mold or be pressed into the cream base with mold, its fire-toxin of decorporating again; The fire-toxin of also can earlier creme being decorporated, repress is made the cream base; Preferably adopt the method for in heating, suppressing that creme is pressed into uniform thin slice creme, again the creme thin slice is washed into the cream base, can certainly prepare the cream base with other method;
2) the cream base of gained is pressed into laminar in heating, its thickness is remained between 0.1~0.9mm;
3) the laminar black plaster of molding is shaped, packs through shearing, and promptly arrives finished product.
When using the method for preparing BAOZHI HEIGAOYAO, can adopt manual machinery, but preferably use the following equipment that designs as said method specially, this equipment comprises transporter, the front end of transporter is provided with and can heats and it is pressed into the uniform flaky temperature control preforming device of thickness creme, be provided with the blank forming device that laminar creme is struck out disk shape cream base after the preforming device, be provided with the ironed device of heating that can heat and simultaneously the cream base is pressed into thin slice behind the blank forming device to the cream base, can also be provided with punching and shearing device after heating ironed device, when the cream base is when being arranged on the back lining materials ironed molding, punching and shearing device can get off the back lining materials shape and the big or small cutting on demand of monoblock, and the below of punching and shearing device preferably is provided with accepts the material-falling hopper of shearing the black plaster that is shaped.For simplifying the preparation method of black plaster, the cream base can be placed be pressed into thin slice on the back lining materials, can before the ironed device of heating, the back lining materials cylinder be set, the back lining materials of reeling on the back lining materials cylinder, be provided with rim charge after the punching and shearing device and reclaim cylinder, rim charge reclaims cylinder coiling back lining materials, the drive back lining materials transmits, make back lining materials move to blank forming device below, allow the cream base of drawing fall on the back lining materials, back lining materials carry the cream base move to together the ironed device place that heats heat ironed, once-forming.Can certainly directly be transporter with the back lining materials.For can being placed between back lining materials and the overlay film, the cream base is pressed into thin slice, also can be provided with the overlay film cylinder before heating ironed device, the overlay film of reeling on the overlay film cylinder, set rim charge reclaims cylinder coiling overlay film and drives overlay film and transmits after the punching and shearing device, overlay film is sent to the upper end of heating ironed device place, cream base, heats ironed device the cream base is sandwiched in once ironed shaping between back lining materials and the overlay film.When the preparation black plaster, earlier creme is placed on the transporter, creme is transferred into the temperature control preforming device earlier, after being pressed into lamellar through the temperature control preforming device, be transferred into the blank forming device, it is consistent to strike out size through the blank forming device, the uniform cream base of thickness, the cream base is placed between back lining materials and the overlay film, being pressed into the plaster layer thickness through the ironed device of heating again is the laminar of 0.1~0.9mm, the laminar black plaster of molding is transferred into punching and shearing device and shears then, black plaster after the shearing falls to material-falling hopper, preferably the black plaster in the material-falling hopper is delivered to packing device and packs, and promptly obtains the finished product black plaster.
Black cream uniform specification with the method for the invention preparation, quality is frivolous, appearance looks elegant, even, the size unanimity of thickness, the thickness of its plaster layer can match in excellence or beauty with rubber unguentum, and because this black plaster need not heat and can directly be affixed on the position, affected part,, tear plaster during bathing, dry skin afterwards and still can paste reposition so use also very conveniently, can take off subsides repeatedly repeatedly, curative effect can be guaranteed 12 hours~5 days; And the thin control equipment of black plaster of the present invention simple in structure, be convenient to operation, what break traditions spreads out creme the original manufacture method that is applied to back lining materials with manual mode, realized the mechanization continuous production of black plaster molding, and significantly improved the production efficiency of black plaster, also avoided the long-time close contact black plaster of producers high temperature process process and unhealthful.
(4) description of drawings:
Fig. 1 is the structural representation of the thin control equipment of black plaster of the present invention;
Fig. 2 is the structural representation of BAOZHI HEIGAOYAO of the present invention.
(5) specific embodiment:
Below in conjunction with accompanying drawing black plaster make-up machine of the present invention is elaborated: be illustrated in figure 1 as the thin control equipment of black plaster of the present invention, comprise the transporter that transmits creme, transporter is a back lining materials 1, being specially back lining materials 1 is wound on the back lining materials cylinder 7, rim charge reclaims cylinder 8 coiling back lining materials, drive back lining materials 1 motion, the front end of back lining materials 1 is provided with the preforming device 2 of heating, the preforming device 2 of heating is provided with blank forming device 3 afterwards, blank forming device 3 rears are provided with the ironed device 4 of heating that the cream base can be pressed into thin slice, be provided with punching and shearing device 5 after heating ironed device 4, punching and shearing device 5 belows are provided with accepts the material-falling hopper 6 of shearing the black plaster that is shaped; After blank forming device 3, also be provided with overlay film cylinder 9, be wound with overlay film on the overlay film cylinder 9, rim charge recovery cylinder 8 is arranged at after the punching and shearing device 5 in the present embodiment, rim charge reclaims cylinder 8 reel simultaneously overlay film and back lining materials 1, and the transmission of drive back lining materials and overlay film, back lining materials 1 is delivered to blank forming device 3 with the cream base, after punching press is good the cream base delivered to the ironed device of heating 4 places, simultaneously overlay film is delivered to the ironed device of heating 4 places, cream base top, the cream base that the ironed device 4 of heating will be sandwiched between back lining materials and the overlay film is heated ironed, deliver to the punching of punching and shearing device 5 places then and be shaped, the black plaster after the punching falls to material-falling hopper 6.
BAOZHI HEIGAOYAO of the present invention as shown in Figure 2, comprise back lining materials layer 10 and plaster layer 11 attached to it, it is laminar uniformly that described plaster layer 11 is thickness, its edge thickness successively decreases and is mild transition shape, its thickness is 0.1~0.9mm, and plaster layer 11 is provided with the overlay film 12 that it can be covered fully.
Embodiment 1:
Adopt black plaster make-up machine shown in Figure 1 to prepare black plaster of the present invention:
1) creme of getting the old tender appropriateness and the fire-toxin of decorporating places on the back lining materials 1 of the thin control equipment of black plaster shown in Figure 1, and creme is transferred into the temperature control preforming device 2 of back lining materials 1 front end then, and 2 heating are pressed into lamellar through the temperature control preforming device;
2) be pressed into flaky creme and be sent to blank forming device 3, strike out size unanimity, the uniform cream base of thickness through blank forming device 3 by back lining materials 1;
3) overlay film is covered on the cream base, makes the cream base be between back lining materials and the covering, add drop stamping through ironed device 4 then, obtaining the plaster layer thickness is 0.9mm;
4) the thin rounded flakes shape black plaster of gained is transferred into punching and shearing device 5 and shears, and the black plaster after the shearing promptly falls to the material-falling hopper 6 that is positioned at the punching and shearing device below, at last the black plaster in the material-falling hopper 6 is packed, and promptly obtains the finished product black plaster.
Embodiment 2:
1) creme of getting the old tender appropriateness and the fire-toxin of decorporating places on the back lining materials 1 of the thin control equipment of black plaster shown in Figure 1, and creme is transferred into the temperature control preforming device 2 of back lining materials 1 front end then, and 2 heating are pressed into lamellar through the temperature control preforming device;
2) be pressed into flaky creme and be sent to blank forming device 3, strike out size unanimity, the uniform cream base of thickness through blank forming device 3 by back lining materials 1;
3) overlay film is covered on the cream base, makes the cream base be between back lining materials and the covering, add drop stamping through ironed device 4 then, obtaining the plaster layer thickness is 0.1mm;
4) the thin rounded flakes shape black plaster of gained is transferred into punching and shearing device 5 and shears, and the black plaster after the shearing promptly falls to the material-falling hopper 6 that is positioned at the punching and shearing device below, at last the black plaster in the material-falling hopper 6 is packed, and promptly obtains the finished product black plaster.
Embodiment 3:
1) creme of getting the old tender appropriateness and the fire-toxin of decorporating places on the back lining materials 1 of the thin control equipment of black plaster shown in Figure 1, and creme is transferred into the temperature control preforming device 2 of back lining materials 1 front end then, and 2 heating are pressed into lamellar through the temperature control preforming device;
2) be pressed into flaky creme and be sent to blank forming device 3, strike out size unanimity, the uniform cream base of thickness through blank forming device 3 by back lining materials 1;
3) overlay film is covered on the cream base, makes the cream base be between back lining materials and the covering, add drop stamping through ironed device 4 then, obtaining the plaster layer thickness is 0.3mm;
4) the thin rounded flakes shape black plaster of gained is transferred into punching and shearing device 5 and shears, and the black plaster after the shearing promptly falls to the material-falling hopper 6 that is positioned at the punching and shearing device below, at last the black plaster in the material-falling hopper 6 is packed, and promptly obtains the finished product black plaster.

Claims (17)

1, BAOZHI HEIGAOYAO, comprise back lining materials layer and plaster layer attached to it, it is characterized in that: described plaster layer (11) is to make the cream base by the creme that boils, and gained cream base is pressed into thickness laminar making uniformly with the ironed device of heating in heating, its thickness is 0.1~0.9mm.
2, BAOZHI HEIGAOYAO according to claim 1 is characterized in that: the thickness of described plaster layer (11) is 0.2~0.6mm.
3, BAOZHI HEIGAOYAO according to claim 2 is characterized in that: the thickness of described plaster layer (11) is 0.3~0.5mm.
4, according to any one described BAOZHI HEIGAOYAO in the claim 1~3, it is characterized in that: it is laminar uniformly that described plaster layer (11) is thickness, and its edge thickness successively decreases and is mild transition shape.
5, according to any one described BAOZHI HEIGAOYAO in the claim 1~3, it is characterized in that: described plaster layer (11) is for circular, and its diameter is 3~8cm.
6, according to any one described BAOZHI HEIGAOYAO in the claim 1~3, it is characterized in that: plaster layer (11) is provided with the overlay film (12) that it can be covered fully.
7, according to any one described BAOZHI HEIGAOYAO in the claim 1~3, it is characterized in that: be laminar with being pressed in the creme heating when making the cream base, the reuse grinding tool strikes out that size is consistent, the uniform lamellar cream of thickness base.
8, the thin system method of the described black plaster of claim 1 the steps include:
1) gets the creme that boils and make the cream base;
2) the cream base of gained is pressed into laminar in heating with the ironed device of heating, its thickness is remained between 0.1~0.9mm;
3) the laminar black plaster of molding is shaped, packs through shearing, and promptly arrives finished product.
9, the thin system method of black plaster according to claim 8 is characterized in that: in the step 1), be laminar with being pressed in the creme heating when making the cream base, the reuse grinding tool strikes out that size is consistent, the uniform lamellar cream of thickness base.
10, according to Claim 8 or the thin system method of 9 described black plasters, it is characterized in that: step 2) in, it is the laminar of 0.2~0.6mm that the cream base is pressed into thickness.
11, the thin system method of black plaster according to claim 10 is characterized in that: step 2) in, it is the laminar of 0.3~0.5mm that the cream base is pressed into thickness.
12, according to Claim 8 or the thin system method of 9 described black plasters, it is characterized in that: step 2) in, it is laminar uniformly that the cream base is pressed into thickness, and its edge thickness successively decreases and is mild transition shape.
13, according to Claim 8 or the thin system method of 9 described black plasters, it is characterized in that: step 2) in, the cream base is pressed into the thin rounded flakes shape that diameter is 3~8cm.
14, according to Claim 8 or the thin system method of 9 described black plasters, it is characterized in that: step 2) in, earlier overlay film is covered on the cream base, the cream base is placed cover and back lining materials between, in to the heating of cream base, it is pressed into laminar again.
15, the thin control equipment of the described black plaster of claim 1, it is characterized in that: comprise transporter, the front end of transporter is provided with heats creme and ironed temperature control preforming device (2), temperature control preforming device (2) is provided with afterwards and strikes out flaky blank forming device (3) with being pressed into even laminar creme, is provided with the ironed device of heating (4) that the cream base can be pressed into thin slice behind the blank forming device (3).
16, the thin control equipment of black plaster according to claim 15, it is characterized in that: described transporter is back lining materials (1), back lining materials (1) is wound on the back lining materials cylinder (7), rim charge reclaims the back lining materials (1) on cylinder (8) the coiling back lining materials cylinder (7), drive the transmission of back lining materials (1), and make back lining materials (1) carry creme to temperature control preforming device (2), blank forming device (3) and heat ironed device (4) and locate.
17, the thin control equipment of black plaster according to claim 16, it is characterized in that: heat ironed device (4) and also be provided with the overlay film cylinder (9) that is wound with overlay film before, rim charge reclaims the overlay film on cylinder (8) the coiling overlay film cylinder (9), drive the transmission of overlay film, and overlay film is sent to heating ironed device (4) and punching and shearing device (5) is located, the upper end of cream base, heat ironed device (4) and be provided with punching and shearing device (5) afterwards, punching and shearing device (5) below is provided with accepts the material-falling hopper (6) of shearing the black plaster that is shaped.
CNB2006100201186A 2006-01-02 2006-01-02 Thin plaster, plaster thinning making method and apparatus Expired - Fee Related CN100352425C (en)

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Application Number Priority Date Filing Date Title
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Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101912346B (en) * 2010-08-19 2013-06-19 常州市泛亚微透科技有限公司 High-speed patch production line
CN103110518B (en) * 2013-03-08 2014-05-14 桂林电子科技大学 Automatic spread coating machine of black plaster
CN106580705B (en) * 2015-12-18 2019-04-16 南京理工大学 A kind of full-automatic plaster machine based on the sticky plaster coat forming of weight
CN113750171A (en) * 2021-08-30 2021-12-07 皖南医学院 A kind of diuretic plaster for relieving ascites and preparation technology thereof

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关于中药黑膏药的质量问题 李向高.江西医药杂志,第4卷第9期 1964 *

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