CN101361994A - Artificial heart blood pump that raises blood pressure step by step - Google Patents
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Abstract
逐级提高血压的人工心脏血泵,属于生物医学工程技术领域,涉及一种提高血压的人工心脏血泵。该人工心脏血泵,包括驱动定子和转子,由与驱动定子连接的控制器提供驱动电源,环形线圈构成的驱动定子位于圆柱形外壳13与管形内腔10构成的夹层内;内腔10中含有支撑转子的位于内腔10前端的头导叶片1和位于内腔10后部的尾导叶片8,以及位于头导叶片1和尾导叶片8之间的转子;其特征在于:该人工心脏血泵分为前后两级,前级为一级血泵;后级为二级血泵;一级血泵和二级血泵由控制器分别驱动。血液首先流经一级血泵产生一个血压,又通过二级血泵再产生一个血压,两个血压叠加起来可以达到人体需要的血压,这样避免了单个泵工作时为了达到较高的血压而增加叶轮转速造成的损伤血红细胞的问题。
An artificial heart blood pump for increasing blood pressure step by step belongs to the technical field of biomedical engineering and relates to an artificial heart blood pump for increasing blood pressure. The artificial heart blood pump includes a drive stator and a rotor, and a drive power supply is provided by a controller connected to the drive stator. The drive stator composed of a ring coil is located in the interlayer formed by the cylindrical shell 13 and the tubular lumen 10; in the lumen 10 Contains the head guide vane 1 located at the front end of the inner cavity 10 supporting the rotor, the tail guide vane 8 located at the rear of the inner cavity 10, and the rotor located between the head guide vane 1 and the tail guide vane 8; it is characterized in that: the artificial heart The blood pump is divided into front and back two stages, the former stage is the first-stage blood pump; the latter stage is the second-stage blood pump; the first-stage blood pump and the second-stage blood pump are respectively driven by the controller. The blood first flows through the first-level blood pump to generate a blood pressure, and then through the second-level blood pump to generate another blood pressure. The two blood pressures can be superimposed to achieve the blood pressure required by the human body, which avoids the need to increase blood pressure when a single pump works to achieve a higher blood pressure. The problem of damage to red blood cells caused by impeller speed.
Description
技术领域 technical field
本发明属于生物医学工程技术领域,涉及一种逐级提高血压的人工心脏血泵。The invention belongs to the technical field of biomedical engineering, and relates to an artificial heart blood pump for increasing blood pressure step by step.
背景技术 Background technique
人工心脏按其血泵工作原理可以分为容积式和叶轮式两种。多款叶轮式人工心脏由于其结构比较简单而且体积小巧已经被应用于临床,但同时,溶血问题困扰着叶轮血泵的使用安全。目前,叶轮血泵大多为单级的血泵,此种血泵典型的结构中仅有一套补偿血压和提供血流的血泵单元,因此需要巨大的抽吸力来满足血压和血流率的要求。如专利号为US2006241335A1的专利文件中,血泵由一个叶轮提供血压和血流,前端抽吸力大,有产生负压的可能,这样对血细胞会造成溶血。另外,磁悬浮转子血泵(申请号200710039971.7)的高转速导致的高剪切力对于血红细胞的破坏相当大,由此造成的溶血性能问题无法克服。The artificial heart can be divided into two types according to the working principle of the blood pump: volumetric type and impeller type. A variety of impeller-type artificial hearts have been used clinically due to their relatively simple structure and small size, but at the same time, the problem of hemolysis has plagued the use of impeller blood pumps. At present, most impeller blood pumps are single-stage blood pumps. In the typical structure of this type of blood pump, there is only one set of blood pump units that compensate blood pressure and provide blood flow. Therefore, huge suction force is required to meet the requirements of blood pressure and blood flow rate. Require. For example, in the patent document US2006241335A1, the blood pump provides blood pressure and blood flow by an impeller, and the suction force at the front end is large, which may generate negative pressure, which will cause hemolysis to blood cells. In addition, the high shear force caused by the high rotational speed of the magnetic levitation rotor blood pump (application number 200710039971.7) is quite damaging to red blood cells, and the hemolytic performance problem caused by this cannot be overcome.
发明内容 Contents of the invention
本发明的目的是提供一种两级的人工心脏血液泵,以解决在保证血红细胞不被破坏的前提下,血压压差不足的问题。The purpose of the present invention is to provide a two-stage artificial heart blood pump to solve the problem of insufficient blood pressure difference under the premise of ensuring that the red blood cells are not destroyed.
为了实现上述目的,本发明采取了如下技术方案:逐级提高血压的人工心脏血泵,包括驱动定子和转子,由与驱动定子连接的控制器提供驱动电源,环形线圈构成的驱动定子位于圆柱形外壳13与管形内腔10构成的夹层内,外壳13的一端密封,另一端由环形端盖11密封;内腔10中含有支撑转子的位于内腔10前端的头导叶片1和位于内腔10后部的尾导叶片8,以及位于头导叶片1和尾导叶片8之间的转子;其中转子为叶轮;且在内腔10后端设有整流尾锥9,其特征在于:该人工心脏血泵分为前后两级,前级为一级血泵,包含一级叶轮3、一级驱动定子13;后级为二级血泵,包含二级叶轮5、二级驱动定子12;在一级叶轮3和二级叶轮5之间设有中导叶片4,作为一级血泵的尾导叶片8,同时作为二级血泵的头导叶片1,且用于支撑一级叶轮3和二级叶轮5;一级驱动定子13和二级驱动定子12由控制器分别驱动,且保证一级血泵的功率大于二级血泵的功率。In order to achieve the above object, the present invention adopts the following technical scheme: the artificial heart blood pump that increases blood pressure step by step includes a drive stator and a rotor, and the drive power is provided by a controller connected to the drive stator. The drive stator composed of a ring coil is located in a cylindrical In the interlayer formed by the
为了血液流通不出现过度抽吸现象,要求一级血泵的功率要大于二级血泵的功率。本发明中一级驱动定子13的线圈匝数大于二级驱动定子12的线圈匝数,且一级叶轮3的长度大于二级叶轮5的长度。这样,当控制器给两个驱动定子的线圈提供同样的控制信号时,一级血泵的功率会大于二级血泵的功率,这样可以简化本装置。In order to avoid excessive suction for blood circulation, the power of the primary blood pump is required to be greater than that of the secondary blood pump. In the present invention, the coil turns of the
本人工血泵的一级叶轮3和二级叶轮5分别通过一级轴承2和二级轴承6套在固定于头导叶片1、中导叶片4和尾导叶片8中心轴线上的固定轴7上。且一级叶轮3和二级叶轮5以及中导叶片4和尾导叶片8采用螺旋叶片,且一级叶轮3和二级叶轮5的螺旋方向与中导叶片4和尾导叶片8的螺旋方向相反。The first-stage impeller 3 and the second-stage impeller 5 of the artificial blood pump are set on the
与一级血泵和二级血泵类似,本人工心脏血泵可以设置两级以上的多级血泵。Similar to the primary blood pump and the secondary blood pump, the artificial heart blood pump can be provided with a multi-stage blood pump with more than two stages.
本发明的有益效果是:1)由于采用两级以上血泵方案,可以在不提高转子转速的前提下使血泵的进口与入口之间的血压压差达到符合人体要求的数值,避免了转子转速过高造成的对血红细胞的破坏。2)采用固定轴,叶轮在固定轴上转动,实验证明,这样有利于减小泵的阻力。The beneficial effects of the present invention are: 1) Due to the adoption of two or more blood pump schemes, the blood pressure pressure difference between the inlet and the inlet of the blood pump can reach a value that meets the requirements of the human body without increasing the rotational speed of the rotor, avoiding the need for rotor Damage to red blood cells caused by excessive rotational speed. 2) A fixed shaft is adopted, and the impeller rotates on the fixed shaft. Experiments have proved that this is beneficial to reduce the resistance of the pump.
附图说明 Description of drawings
图1为本发明逐级提高血压的人工心脏血泵的结构示意图Fig. 1 is the structural representation of the artificial heart blood pump that increases blood pressure step by step in the present invention
图中:1、头导叶片,2、一级轴承,3、一级叶轮,4、中导叶片,5、二级叶轮,6、二级轴承,7、固定轴,8、尾导叶片,9、整流尾锥,10、内腔,11、端盖,12、二级驱动定子,13、一级驱动定子,14、外壳。In the figure: 1. Head guide vane, 2. Primary bearing, 3. Primary impeller, 4. Middle guide vane, 5. Secondary impeller, 6. Secondary bearing, 7. Fixed shaft, 8. Tail guide vane, 9. Rectifier tail cone, 10. Inner cavity, 11. End cover, 12. Secondary drive stator, 13. Primary drive stator, 14. Shell.
具体实施方式 Detailed ways
如图1所示,本发明公开的逐级提高血压的人工心脏血泵主要包括外壳13和内腔10两部分,外壳13和内腔10皆为圆筒状,采用医用钛合金TC4材料制作。外壳13套在内壳外形成夹层,夹层内放置定子线圈;外壳13一端用环形侧板与内腔10密封连接,另一端通过环形端盖11与内腔10密封连接。内腔10内依次放置头导叶片1、一级叶轮3、中导叶片4、二级叶轮5、尾导叶片8、整流尾锥9;头导叶片1、中导叶片4、尾导叶片8与内腔壁固定;在头导叶片1和中导叶片4、中导叶片4和尾导叶片8的轴心线上固定有固定轴7,一级叶轮3和二级叶轮5分别通过一级轴承2和二级轴承6套在固定轴7上。头导叶片1的叶片为2-4片,采用顺着内腔方向的直片;一级叶轮3、中导叶片4、二级叶轮5、尾导叶片8的叶片为螺旋状(见图1),一级叶轮3和二级叶轮5的螺旋方向与中导叶片4和尾导叶片8的螺旋方向相反。内腔10的尾端为整流尾锥9,整流尾锥9固定在尾导叶片8上。As shown in FIG. 1 , the artificial heart blood pump for increasing blood pressure step by step disclosed by the present invention mainly includes two parts: an
一级叶轮3和二级叶轮5内按常规方式均匀嵌有永磁体,当定子线圈与控制器接通时与电极定子作用使叶轮转动。一级叶轮3和二级叶轮5转采用医用钛合金TC4材料制作,固定轴7的直径小于叶轮本身直径的一半,且叶轮中叶片的厚度不超过1毫米。定子线圈为三相线圈,控制器具有三相电流型PWM控制功能。The first-stage impeller 3 and the second-stage impeller 5 are evenly embedded with permanent magnets in a conventional manner, and when the stator coil is connected to the controller, it interacts with the electrode stator to make the impeller rotate. The first-stage impeller 3 and the second-stage impeller 5 are made of medical titanium alloy TC4 material, the diameter of the
为了血液流通不出现过度抽吸现象,要求一级血泵的功率要大于二级血泵的功率。本发明中一级驱动定子13的线圈匝数大于二级驱动定子12的线圈匝数,相应地一级叶轮3的长度大于二级叶轮5的长度,这样,当控制器给两个驱动定子的线圈提供同样的控制信号时,一级血泵的功率会大于二级血泵的功率,这样可以简化本装置。当然,控制器也可以为一级驱动定子13和二级驱动定子12的线圈提供不同的控制信号,这样可分别调整两个血泵的功率。In order to avoid excessive suction for blood circulation, the power of the primary blood pump is required to be greater than that of the secondary blood pump. Among the present invention, the number of coil turns of the first-
本装置工作时,血液首先流经一级血泵产生一个血压,又通过二级血泵再产生一个血压,两个血压叠加起来可以达到人体需要的血压。这样避免了单级泵工作时为了达到较高的血压而增加叶轮转速造成的损伤血红细胞的问题。为了进一步减小对血红细胞的破坏,即降低血泵的转速,可以采用更多级的血泵来达到需要的血压。各级血泵的结构与上面介绍的相同,由控制器分别控制。When the device works, the blood first flows through the first-stage blood pump to generate a blood pressure, and then passes through the second-stage blood pump to generate another blood pressure. The superimposition of the two blood pressures can reach the blood pressure required by the human body. This avoids the problem of red blood cell damage caused by increasing the impeller speed to achieve higher blood pressure when the single-stage pump is working. In order to further reduce the damage to red blood cells, that is, to reduce the speed of the blood pump, more stages of blood pumps can be used to achieve the required blood pressure. The structure of the blood pumps at all levels is the same as that introduced above, and is controlled by the controller respectively.
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| CN101513545B (en) * | 2009-04-03 | 2011-07-13 | 北京工业大学 | Multi-mode ventricle auxiliary blood pump controller |
| US8690749B1 (en) | 2009-11-02 | 2014-04-08 | Anthony Nunez | Wireless compressible heart pump |
| CN104564694A (en) * | 2014-12-26 | 2015-04-29 | 江苏大学 | A compact axial flow pump |
| CN107050543A (en) * | 2017-05-04 | 2017-08-18 | 浙江理工大学 | A kind of microminiature micro-centrifugal blood pump with self-regulation blade |
| CN108744102A (en) * | 2018-07-04 | 2018-11-06 | 威海威高血液净化制品有限公司 | The interior enhanced dialyzer of filtration |
| US10722631B2 (en) | 2018-02-01 | 2020-07-28 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of use and manufacture |
| CN112312835A (en) * | 2018-06-11 | 2021-02-02 | 苏黎世大学 | Blood pump for mechanical circulatory support in Fontan patients |
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| US8690749B1 (en) | 2009-11-02 | 2014-04-08 | Anthony Nunez | Wireless compressible heart pump |
| CN104564694A (en) * | 2014-12-26 | 2015-04-29 | 江苏大学 | A compact axial flow pump |
| CN107050543A (en) * | 2017-05-04 | 2017-08-18 | 浙江理工大学 | A kind of microminiature micro-centrifugal blood pump with self-regulation blade |
| CN107050543B (en) * | 2017-05-04 | 2023-07-04 | 浙江理工大学 | Microminiature centrifugal blood pump with self-adjusting blades |
| US11717670B2 (en) | 2017-06-07 | 2023-08-08 | Shifamed Holdings, LLP | Intravascular fluid movement devices, systems, and methods of use |
| US11185677B2 (en) | 2017-06-07 | 2021-11-30 | Shifamed Holdings, Llc | Intravascular fluid movement devices, systems, and methods of use |
| US11511103B2 (en) | 2017-11-13 | 2022-11-29 | Shifamed Holdings, Llc | Intravascular fluid movement devices, systems, and methods of use |
| US10722631B2 (en) | 2018-02-01 | 2020-07-28 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of use and manufacture |
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| US12109404B2 (en) | 2018-06-11 | 2024-10-08 | Universität Zürich | Blood pump for mechanical circulatory support for Fontan patients |
| CN112312835A (en) * | 2018-06-11 | 2021-02-02 | 苏黎世大学 | Blood pump for mechanical circulatory support in Fontan patients |
| CN108744102A (en) * | 2018-07-04 | 2018-11-06 | 威海威高血液净化制品有限公司 | The interior enhanced dialyzer of filtration |
| CN108744102B (en) * | 2018-07-04 | 2024-08-09 | 山东威高血液净化制品股份有限公司 | Internal filtering enhanced dialyzer |
| US11964145B2 (en) | 2019-07-12 | 2024-04-23 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of manufacture and use |
| US11654275B2 (en) | 2019-07-22 | 2023-05-23 | Shifamed Holdings, Llc | Intravascular blood pumps with struts and methods of use and manufacture |
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| CN114177516B (en) * | 2021-12-22 | 2024-05-14 | 江苏大学 | High-flow two-stage catheter pump for left ventricle assistance and application method thereof |
| CN114177516A (en) * | 2021-12-22 | 2022-03-15 | 江苏大学 | High-flow two-stage catheter pump for left ventricle assistance and using method thereof |
| CN115779257A (en) * | 2022-11-15 | 2023-03-14 | 北京航空航天大学 | Novel intervention catheter pump |
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