CN102217618B - A bactericidal composition containing trifloxystrobin and antibiotic compounds - Google Patents

Abstract

The invention discloses a bactericidal composition containing trifloxystrobin and an antibiotic compound, which comprises active components A and B, wherein the active component A is selected from trifloxystrobin, and the active component B is selected from any one of the following bactericides: validamycin, zhongshengmycin, kasugamycin and polyoxin, wherein the weight part ratio of the A, B active components is 64: 1-1: 64. The composition can prevent and treat various crop diseases, has obvious synergistic effect, expands the bactericidal spectrum, and has higher activity on diseases such as rice blast, banded sclerotial blight, glume blight, damping off, powdery mildew, leaf spot, downy mildew, fusarium wilt, gray mold, leaf mold and the like; and the dosage of the pesticide is reduced, the residual quantity of the pesticide on crops is reduced, and the environmental pollution is reduced.

Description

A bactericidal composition containing trifloxystrobin and antibiotic compounds

technical field

The invention belongs to the technical field of pesticides, and relates to a bactericidal composition containing trifloxystrobin and antibiotic compounds.

Background technique

Trifloxystrobin, molecular formula: C ₂₀ H ₁₉ F ₃ N ₂ O ₄ , chemical name: methyl(E)-methoxyimino-{(E)-α-[1-(α,α -trifluoro-m-tolyl)-ethylideneaminooxy]-o-tolyl}ethyl acetate. Trifloxystrobin broad-spectrum fungicides are a new class of fluorine-containing fungicides successfully developed from natural products Strobilurins as fungicide lead compounds. It has the characteristics of high efficiency, broad spectrum, protection, treatment, eradication, penetration, systemic activity, resistance to rain erosion, and long-lasting effect. It is effective for strains resistant to 1,4-demethylase inhibitors, benzamides, dicarboxylamines and benzimidazoles, and has no cross-resistance with existing fungicides. It has good activity against almost all fungal diseases (Ascomycetes, Basidiomycetes, Oomycetes and Deuteromycetes) such as powdery mildew, rust, blight, net spot, downy mildew, rice blast, etc. . It is safe for crops, and it is safe for the environment because it can be rapidly degraded in soil and water.

In the actual process of agricultural production, the long-term use of trifloxystrobin single-dose is likely to cause the problem of bacterial resistance. The compounding of ingredients from different varieties is a very common way to prevent and control resistant bacteria. Different ingredients are compounded, and according to the actual application effect, it is judged whether a certain compound is synergistic, additive or antagonistic. In most cases, the compounding effects of pesticides are additive effects, and there are very few compoundings that really have synergistic effects, especially those with very obvious synergistic effects and high synergistic ratios. After research by the inventor, it was found that trifloxystrobin and Jinggangmycin, Zhongshengmycin, Kasugamycin and polyoxin can produce a good synergistic effect after compounding, and about trifloxystrobin and Jinggangmycin, The relevant reports on the combination of Zhongshengmycin, Kasugamycin and polyoxin have not been made public at home and abroad.

Contents of the invention

A bactericidal composition containing trifloxystrobin and antibiotic compounds, including effective active ingredients, auxiliary agents and fillers, characterized in that: the ratio of parts by weight of A and B is 64:1 to 1:64, and the active ingredient A is selected from Trifloxystrobin, the active ingredient B is selected from one of the antibiotic compounds Jinggangmycin, Zhongshengmycin, Kasugamycin and polyoxin.

The bactericidal composition containing trifloxystrobin and antibiotic compounds is characterized in that the ratio of active components A and B is 16:1-1:16 by weight.

The bactericidal composition containing trifloxystrobin is characterized in that the weight ratio of trifloxystrobin to Jinggangmycin is 8:1-1:8.

The bactericidal composition containing trifloxystrobin is characterized in that the weight ratio of trifloxystrobin to Zhongshengmycin is 8:1-1:8.

The bactericidal composition containing trifloxystrobin is characterized in that the weight ratio of trifloxystrobin to kasugamycin is 8:1-1:8.

The bactericidal composition containing trifloxystrobin is characterized in that the weight ratio of trifloxystrobin to polyoxin is 8:1-1:8.

Usually the weight percentage of the active ingredient in the composition is 1-90% of the total weight, preferably 5%-60%. Depending on the type of preparation, the content range of the active ingredient is different. Usually, liquid preparations contain 1-60% active substance by weight, preferably 5-50%; solid preparations contain 1-90% active substance by weight, preferably 5-80%.

The fungicidal composition of the present invention contains at least one surfactant to facilitate the dispersion of active ingredients in water during application. The surfactant content is 5-30% of the total weight of the preparation, and the balance is solid or liquid diluent.

The surfactant selected for the bactericidal composition of the present invention is well known to those skilled in the art: it can be selected from one or more of dispersants, wetting agents, binders or defoamers. According to different dosage forms, the preparation may also contain disintegrants, antifreeze agents and the like known to those skilled in the art.

Described dispersant is selected from alkyl naphthalene sulfonate, double (alkyl) naphthalene sulfonate formaldehyde condensate, naphthalene sulfonate formaldehyde condensate, arylphenol polyoxyethylene succinate sulfonate, octyl Phenol polyoxyethylene ether sulfate, polycarboxylate, lignosulfonate, alkylphenol polyoxyethylene pyrimaldehyde condensate sulfate, alkylbenzenesulfonic acid calcium salt, naphthalenesulfonic acid formaldehyde condensate sodium salt, One or more of alkylphenol polyoxyethylene pyrimide, fatty amine polyoxyethylene pyrimide, fatty acid polyoxyethylene ester, and ester polyoxyethylene pyrimide.

The wetting agent is selected from one of: sodium lauryl sulfate, sodium dodecylbenzene sulfonate, pull-open powder BX, wetting and penetrating agent F, saponin powder, silkworm excrement, and Sapindus powder or more.

The disintegrating agent is selected from one or more of bentonite, urea, ammonium sulfate and aluminum chloride.

Described binder is selected from: gum arabic, xanthan gum, sodium tripolyphosphate, phenolic resin, sodium alginate, white dextrin, methylcellulose, sodium acrylate, polyvinylpyrrolidone, cross-linked polyvinylpyrrolidone, One or more of polyethylene glycol and polyvinyl alcohol.

The antifreezing agent is selected from one or more of ethylene glycol, propylene glycol, glycerol and polyethylene glycol.

The defoamer is selected from one or more of silicones, C _8-10 fatty alcohols, C _10-20 saturated fatty acids (such as capric acid), amides, silicone oil, and silicone compounds.

Described stabilizer is selected from one or more in sodium sorbate, butyl glycidyl ether, phenyl glycidyl ether, cresyl glycidyl ether, polyvinyl glycol diglycidyl ether;

The filler is selected from one or more of kaolin, diatomite, bentonite, attapulgite, white carbon black, starch, and light calcium carbonate.

The compositions of the present invention may be diluted before use or used directly by the user. Its preparation can be prepared by common processing methods, that is, after mixing the active substance with a liquid solvent or a solid carrier, and then adding one or more surfactants such as dispersants, stabilizers, wetting agents, adhesives, defoamers, etc. kind.

The fungicidal composition of the present invention can be processed into any pesticide-acceptable dosage form as required, wherein the preferred dosage forms include: wettable powder, water-dispersible granule, suspension concentrate and the like.

When the composition is made into a wettable powder, it contains the following components: 1-64% trifloxystrobin, 1-64% active ingredient B, 5-10% dispersant, 2-10% wetting agent, and 100% filler.

The active ingredient trifloxystrobin, active ingredient B, dispersant, wetting agent, and filler are mixed, mixed evenly in a mixing tank, pulverized by a jet mill, and then mixed evenly to produce the wettable powder product of the present invention .

Main technical index of wettable powder of the present invention:

When the composition is made into water-dispersible granules, the following components are included: active ingredient trifloxystrobin 1-64%, active ingredient B 1-64%, dispersant 3-12%, wetting agent 1-8%, disintegrant 1-10%, binder 1-8%, filler added to 100%.

The active ingredient trifloxystrobin, active ingredient B, dispersant, wetting agent, disintegrant, filler, etc. are jet-milled together to obtain the required particle size, and then other additives such as binder are added to obtain the granulation material. The water-dispersible granule product of the present invention is obtained by quantitatively sending the material into a fluidized bed granulation dryer for granulation and drying.

Water-dispersible granule main technical index of the present invention:

When the composition is made into a suspension, it includes the following components: active ingredient trifloxystrobin 1-50%, active ingredient B 1-32%, dispersant 2-10%, wetting agent 2-10%, defoamer 0.1- 1%, binder 0.1-2%, antifreeze agent 0.1-8%, and deionized water to 100%.

The dispersant, wetting agent, defoamer, thickener, and antifreeze in the above formula are mixed evenly through high-speed shearing, and the active ingredient trifloxystrobin and active ingredient B are added, and ball milled in a ball mill for 2 to 3 hours to make The particle diameters of all the particles are below 5 μm to obtain the suspension product of the present invention.

Suspending agent main technical index of the present invention:

The present invention has the advantages of: (1) after trifloxystrobin and antibiotic compounds are compounded, it has obvious sustained synergistic effect; (2) the bactericidal spectrum is expanded, and it is effective against rice blast, sheath blight, glume blight, and blight , powdery mildew, leaf spot, downy mildew, fusarium wilt, gray mold, leaf mold and other diseases have relatively high activity; (3) the present invention does not use organic solvents, is not easy to produce phytotoxicity, and is convenient for transportation and storage; (4) The dosage of pesticides is reduced, the residues of pesticides on crops are reduced, and environmental pollution is reduced.

Detailed ways

The embodiment of the present invention adopts the method combining indoor virulence determination and field test. The embodiment of the present invention adopts the method combining indoor virulence determination and field test. First, through the indoor toxicity test, the synergistic ratio (SR) of the two agents after compounding in a certain proportion is clarified. SR<0.5 is an antagonistic effect, 0.5≤SR≤1.5 is an additive effect, and SR>1.5 is a synergistic effect. On this basis, field experiments were carried out.

Indoor virulence determination of trifloxystrobin and active ingredient B (B selected from Jinggangmycin, Zhongshengmycin, kasugamycin, and polyoxin) against target bacteria

After the effective inhibitory concentration range of each drug was determined by pre-test, each drug was treated with 5 doses according to the content of active ingredients, and water was used as control. Refer to the "Pesticide Indoor Bioassay Test Guidelines for Fungicides", and use the mycelium growth rate method to determine the toxicity of the agent to the target bacteria. After 72 hours, the colony diameter was measured by the cross method, and the net growth and mycelial growth inhibition rate of each treatment were calculated.

Net growth (mm) = measured colony diameter -5

The mycelia growth inhibition rate was converted into a probability value (y), the concentration of the medicinal solution (μg/mL) was converted into a logarithmic value (x), and the regression equation of virulence (y=a+bx) was obtained by the least square method, and by This calculates the _EC50 value for each agent. At the same time, according to the Wadley method, the synergistic ratio (SR) of the combination of different proportions of the two agents was calculated. SR<0.5 was considered antagonism, 0.5≤SR≤1.5 was additive, and SR>1.5 was synergistic. Calculated as follows:

Wherein: a and b are respectively the proportions of active ingredient trifloxystrobin and active ingredient B (Jinggangmycin, Zhongshengmycin, Kasugamycin, polyoxin) in the combination;

A is trifloxystrobin;

B is one of Jinggangmycin, Zhongshengmycin, Kasugamycin and polyoxin.

Implementation Application Example 1

Indoor Toxicity Determination of Trifloxystrobin and Jinggangmycin Compound to Rice Sheath Blight Disease

All test agents were provided by Shaanxi Thompson Biotechnology Co., Ltd.

Experimental design: Through preliminary experiments, the effective inhibitory concentration ranges of trifloxystrobin, Jinggangmycin and their mixtures with different ratios were determined.

Toxicity test results

Table 1 Analysis table of the toxicity test results of trifloxystrobin, Jinggangmycin and their compound against rice sheath blight

It can be known from Table 1 that the EC ₅₀ of trifloxystrobin and Jinggangmycin against rice sheath blight were 0.65 mg/L and 0.78 mg/L, respectively. When the ratio of trifloxystrobin and Jinggangmycin is between 64:1 and 1:64, the synergistic ratio SR is greater than 1.5, indicating that trifloxystrobin and Jinggangmycin are mixed in the range of 64:1 to 1:64. Show synergy, especially when the ratio of the two is 8:1 to 1:8, the synergy is the most obvious.

Implement application example 2

Indoor Toxicity Determination of Trifloxystrobin and Zhongshengmycin for Banana Leaf Spot Disease

All test agents were provided by Shaanxi Thompson Biotechnology Co., Ltd.

Experimental design: Through preliminary experiments, the effective inhibitory concentration ranges of trifloxystrobin, Zhongshengmycin and their mixtures with different ratios were determined.

Toxicity test results

Table 2 Analysis table of toxicity test results of trifloxystrobin, Zhongshengmycin and their compound against banana leaf spot

It can be known from Table 2 that the EC ₅₀ of trifloxystrobin and Zhongshengmycin against banana leaf spot were 1.12 mg/L and 0.96 mg/L, respectively. When the ratio of trifloxystrobin and Zhongshengmycin is 64:1 to 1:64, the synergistic ratio SR is greater than 1.5, indicating that trifloxystrobin and Zhongshengmycin are mixed in the range of 64:1 to 1:64. Both of them showed synergistic effect, especially when the ratio of the two was between 8:1 and 1:8, the synergistic effect was more prominent.

Implement application example three:

Indoor toxicity determination of trifloxystrobin and kasugamycin against wheat powdery mildew.

All test agents were provided by Shaanxi Thompson Biotechnology Co., Ltd.

Experimental design: The effective inhibitory concentration ranges of trifloxystrobin, kasugamycin and their mixtures with different ratios were determined through preliminary experiments.

Toxicity test results

Table 3 Analysis table of toxicity test results of trifloxystrobin, kasugamycin and their compound against wheat powdery mildew

It can be seen from Table 3 that the EC ₅₀ of trifloxystrobin and kasugamycin against wheat powdery mildew were 0.81 mg/L and 0.73 mg/L, respectively. When the ratio of trifloxystrobin and kasugamycin is between 64:1 and 1:64, the synergistic ratio SR is greater than 1.5, indicating that the mixture of trifloxystrobin and kasugamycin in the range of 64:1 to 1:64 all perform well. Synergistic effect, especially when the ratio of the two is 8:1 to 1:8, the synergistic effect is more prominent.

Implementation Application Example 4

Toxicity determination of trifloxystrobin and polyoxin compound against tomato leaf mold

All test agents were provided by Shaanxi Thompson Biotechnology Co., Ltd.

Experimental design: The effective inhibitory concentration ranges of trifloxystrobin, polyoxin and their mixtures with different ratios were determined through preliminary experiments.

Toxicity test results

Table 2 Analysis table of toxicity test results of trifloxystrobin, polyoxin and their compound against tomato leaf mold

It can be known from Table 2 that the EC ₅₀ of trifloxystrobin and polyoxin against tomato leaf mold were 0.70 mg/L and 0.58 mg/L, respectively. When the ratio of trifloxystrobin and polyoxin is 64:1 to 1:64, the synergistic ratio SR is greater than 1.5, indicating that trifloxystrobin and polyoxin are mixed within the range of 64:1 to 1:64. Both of them showed synergistic effect, especially when the ratio of the two was between 8:1 and 1:8, the synergistic effect was more prominent.

Application Example Four Implementation Formulation Example

The present invention will be further described below in conjunction with the examples. The parts ratios in the examples are all percentages by weight, but the present invention is not limited thereto.

Example 1 20% trifloxystrobin Jinggangmycin wettable powder

Trifloxystrobin 10%, Jinggangmycin 10%, polycarboxylate 3%, Sapindus powder 4%, diatomaceous earth added to 100%, the mixture was jet milled to obtain 20% Trifloxystrobin Jinggangmycin wettable powder.

Example 2 35% trifloxystrobin · Jinggangmycin wettable powder

Add trifloxystrobin 20%, Jinggangmycin 15%, lignosulfonate 3%, wetting and penetrating agent F 3%, attapulgite to 100%, and the mixture is jet milled to obtain 35% trifloxystrobin Jinggang Mycin wettable powder.

Example 3 65% trifloxystrobin Jinggangmycin wettable powder

Trifloxystrobin 60%, Jinggangmycin 5%, arylphenol polyoxyethylene succinate sulfonate 4%, saponin powder 3%, white carbon black were added to 100%, and the mixture was jet milled to obtain 65 % Trifloxystrobin · Jinggangmycin wettable powder.

Example 4 18% trifloxystrobin Jinggangmycin water dispersible granules

Trifloxystrobin 2%, Jinggangmycin 16%, Sodium Lauryl Sulfate 5%, Polyoxyethylene Fatty Acid Ester 3%, Aluminum Chloride 1%, Bentonite 10%, Kaolin to 100%, mixed to make 18% Trifloxystrobin · Jinggangmycin water dispersible granules.

Example 5 28% trifloxystrobin Jinggangmycin water dispersible granules

Trifloxystrobin 4%, Jinggangmycin 24%, Sapindus chinensis powder 3%, naphthalenesulfonic acid formaldehyde condensate sodium salt 4%, bentonite 10%, diatomaceous earth to 100%, mixed to make 28% trifloxystrobin · Jinggangmycin water dispersible granules.

Example 6 45% trifloxystrobin Jinggangmycin water dispersible granules

Trifloxystrobin 40%, Jinggangmycin 5%, saponin powder 5%, alkylbenzene sulfonate calcium salt 4%, urea 1%, kaolin to 100%, mixed to make 45% trifloxystrobin Jinggangmycin Water dispersible granules.

Example 7 15% Trifloxystrobin Jinggangmycin Suspension Concentrate

Trifloxystrobin 5%, Jinggangmycin 10%, polycarboxylate 5%, sodium dodecylbenzenesulfonate 5%, C _8-10 fatty alcohols 0.5%, methylcellulose 1%, propylene glycol 1.6% 1. Add deionized water to 100%, and mix to prepare 15% trifloxystrobin·Jinggangmycin suspension.

Example 8 20% Trifloxystrobin·Jinggangmycin Suspension Concentrate

Trifloxystrobin 4%, Jinggangmycin 16%, naphthalenesulfonate formaldehyde condensate 4%, silkworm excrement 3%, silicone compounds 0.2%, polyvinylpyrrolidone 0.8%, polyethylene glycol 1.5%, deionized water plus to 100%, mixed to prepare 20% Trifloxystrobin·Jinggangmycin suspension.

Example 9 48% Trifloxystrobin Jinggangmycin Suspension Concentrate

Trifloxystrobin 40%, Jinggangmycin 8%, Alkylphenol Polyoxyethylene Pyrimaldehyde Condensate Sulfate 3%, Sodium Dodecylbenzene Sulfonate 4%, C _10-20 Saturated Fatty Acids 0.5%, Trimer Add 1% sodium phosphate, 1.5% glycerol, and deionized water to 100%, and mix to prepare a 48% trifloxystrobin·Jinggangmycin suspension.

Example 10 24% trifloxystrobin · Zhongshengmycin wettable powder

Trifloxystrobin 8%, Zhongshengmycin 16%, naphthalenesulfonic acid formaldehyde condensate sodium salt 3%, silkworm excrement 3%, diatomaceous earth added to 100%, the mixture was jet milled to obtain 24% trifloxystrobin. Zhongshengmycin wettable powder.

Example 11 45% trifloxystrobin · Zhongshengmycin wettable powder

Add trifloxystrobin 30%, Zhongshengmycin 15%, polycarboxylate 3%, pull open powder BX 4%, bentonite to 100%, and the mixture is jet milled to obtain 45% Trifloxystrobin Zhongshengmycin wettable powder.

Example 12 60% trifloxystrobin · Zhongshengmycin wettable powder

Trifloxystrobin 40%, Zhongshengmycin 20%, Lignosulfonate 3%, Sapindus powder 4%, Kaolin clay added to 100%, the mixture was jet milled to obtain 60% Trifloxystrobin·Mesophyte Plain wettable powder.

Example 13 30% trifloxystrobin Zhongshengmycin water dispersible granules

Trifloxystrobin 10%, Zhongshengmycin 20%, alkylphenol polyoxyethylene pyrimaldehyde condensate sulfate 3%, saponin powder 2%, urea 1%, attapulgite to 100%, mixed to make 30 % Trifloxystrobin · Zhongshengmycin water dispersible granules.

Example 14 50% trifloxystrobin Zhongshengmycin water dispersible granules

Trifloxystrobin 40%, Zhongshengmycin 10%, Lignosulfonate 4%, Sapindus powder 4%, Ammonium Sulfate 0.8%, bentonite to 100%, mixed to make 50% Trifloxystrobin Zhongsheng Mycocin water dispersible granules.

Example 15 40% trifloxystrobin Zhongshengmycin water dispersible granules

Trifloxystrobin 15%, Zhongshengmycin 25%, naphthalenesulfonic acid formaldehyde condensate sodium salt 3%, wetting and penetrating agent F 4%, urea 5%, kaolin to 100%, mixed to make 40% trifloxystrobin · Zhongshengmycin water dispersible granules.

Example 16 12% Trifloxystrobin Zhongshengmycin Suspension Concentrate

Trifloxystrobin 4%, Zhongshengmycin 8%, fatty acid polyoxyethylene ester 4%, Sapindus powder 3%, silicone oil 0.3%, xanthan gum 1%, glycerin 1.3%, deionized water added to 100 %, mixed to prepare 12% trifloxystrobin · Zhongshengmycin suspension concentrate.

Example 17 25% Trifloxystrobin Zhongshengmycin Suspension Concentrate

Trifloxystrobin 20%, Zhongshengmycin 5%, Alkylbenzenesulfonate Calcium Salt 3%, Sodium Lauryl Sulfate 4%, Silicone Compounds 0.5%, Sodium Tripolyphosphate 1.5%, Ethylene Glycol 1.5% %, deionized water to 100%, mixed to prepare 25% trifloxystrobin · Zhongshengmycin suspension.

Example 18 40% Trifloxystrobin Zhongshengmycin Suspension Concentrate

Trifloxystrobin 10%, Zhongshengmycin 30%, polycarboxylate 3%, wetting and penetrating agent F 5%, silicone oil 0.2%, polyvinylpyrrolidone 1%, polyethylene glycol 1.6%, deionized water to 100%, mixed to prepare 40% trifloxystrobin · Zhongshengmycin suspension concentrate.

Example 19 18% trifloxystrobin·kasugamycin wettable powder

Add trifloxystrobin 6%, kasugamycin 12%, alkylphenol polyoxyethylene pyrimaldehyde condensate sulfate 3%, silkworm excrement 3%, bentonite to 100%, and the mixture is jet milled to obtain 18% trifloxystrobin · Kasugamycin wettable powder.

Example 20 50% trifloxystrobin·kasugamycin wettable powder

Add trifloxystrobin 40%, kasugamycin 10%, lignosulfonate 3%, saponin powder 5%, diatomaceous earth to 100%, and the mixture is jet milled to obtain 50% trifloxystrobin·kasugamycin wettable powder.

Example 21 65% trifloxystrobin·kasugamycin wettable powder

Add trifloxystrobin 64%, kasugamycin 1%, fatty acid polyoxyethylene ester 3%, wetting penetrant F 4%, kaolin to 100%, and the mixture is jet milled to obtain 65% trifloxystrobin·kasugamycin wettable powder.

Example 22 9% trifloxystrobin·kasugamycin water dispersible granules

Trifloxystrobin 8%, kasugamycin 1%, arylphenol polyoxyethylene succinate sulfonate 3%, pull open powder BX 4%, sodium sulfate 1%, bentonite to 100%, mixed to obtain 9 % trifloxystrobin · kasugamycin water dispersible granules.

Example 23 25% trifloxystrobin·kasugamycin water dispersible granules

Add trifloxystrobin 20%, kasugamycin 5%, aliphatic amine polyoxyethylene 3%, wetting and penetrating agent F 3%, aluminum chloride 0.8%, attapulgite to 100%, and mix to make 25% trifloxacin Ester·kasugamycin water dispersible granules.

Example 24 45% trifloxystrobin·kasugamycin water dispersible granules

Add trifloxystrobin 40%, kasugamycin 5%, naphthalenesulfonic acid formaldehyde condensate 4%, sapindus powder 5%, urea 1.2%, bentonite to 100%, and mix to make 45% trifloxystrobin · kasugamycin Water dispersible granules.

Example 25 27% trifloxystrobin · kasugamycin suspension

Trifloxystrobin 18%, Kasugamycin 9%, Naphthalenesulfonate Formaldehyde Condensate Sodium Salt 4%, Sodium Dodecylbenzenesulfonate 3%, C _8-10 Fatty Alcohols 0.7%, Gum Arabic 0.8%, Propylene Gum Add 1.4% triol and deionized water to 100%, and mix to prepare a 27% trifloxystrobin·kasugamycin suspension.

Example 26 33% trifloxystrobin·kasugamycin suspension concentrate

Trifloxystrobin 32%, kasugamycin 1%, alkylbenzene sulfonate calcium salt 3%, wetting and penetrating agent F4%, silicone oil 0.2%, polyvinylpyrrolidone 1%, polyethylene glycol 1.7%, deionized water plus to 100%, mixed to prepare a 33% trifloxystrobin-kasugamycin suspension.

Example 27 40% trifloxystrobin · kasugamycin suspension

Trifloxystrobin 32%, kasugamycin 8%, fatty acid polyoxyethylene ester 5%, sapindus powder 2%, silicone compounds 0.5%, sodium tripolyphosphate 0.6%, propylene glycol 1.2%, deionized water to 100%, mixed to prepare 40% trifloxystrobin·kasugamycin suspension concentrate.

Example 28 20% trifloxystrobin · polyoxin wettable powder

Trifloxystrobin 12%, polyoxin 8%, polycarboxylate 3%, Sapindus powder 4%, diatomaceous earth added to 100%, the mixture was jet milled to obtain 20% trifloxystrobin · polyoxin Mycin wettable powder.

Example 29 35% trifloxystrobin · polyoxin wettable powder

Trifloxystrobin 25%, polyoxin 10%, lignosulfonate 3%, wetting penetrant F 3%, attapulgite to 100%, the mixture was jet milled to obtain 35% trifloxystrobin. Polyoxin wettable powder.

Example 30 65% trifloxystrobin · polyoxin wettable powder

Trifloxystrobin 60%, polyoxin 5%, arylphenol polyoxyethylene succinate sulfonate 4%, saponin powder 3%, white carbon black added to 100%, the mixture was jet milled to obtain 65% trifloxystrobin · polyoxin wettable powder.

Example 31 18% trifloxystrobin · polyoxin water dispersible granules

Trifloxystrobin 3%, polyoxin 15%, sodium lauryl sulfate 5%, fatty acid polyoxyethylene ester 3%, aluminum chloride 1%, bentonite 10%, kaolin to 100%, mixed to obtain 18 % trifloxystrobin · polyoxin water dispersible granules.

Example 32 28% trifloxystrobin · polyoxin water dispersible granules

Trifloxystrobin 18%, polyoxin 10%, Sapindus powder 3%, naphthalenesulfonate formaldehyde condensate sodium salt 4%, bentonite 10%, diatomaceous earth to 100%, mixed to obtain 28% trifloxacin Ester·polyoxamycin water dispersible granules.

Example 33 45% trifloxystrobin · polyoxin water dispersible granules

Add trifloxystrobin 42%, polyoxin 3%, saponin powder 5%, alkylbenzene sulfonate calcium salt 4%, urea 1%, kaolin to 100%, and mix to make 45% trifloxystrobin · polyoxin Mycin water dispersible granules.

Example 34 15% trifloxystrobin · polyoxin suspension concentrate

Trifloxystrobin 5%, polyoxin 10%, polycarboxylate 5%, sodium dodecylbenzenesulfonate 5%, C _8-10 fatty alcohols 0.5%, methylcellulose 1%, propylene glycol 1.6 %, deionized water was added to 100%, and mixed to prepare a 15% trifloxystrobin · polyoxin suspension.

Example 35 20% Trifloxystrobin · Polyoxin Suspension Concentrate

Trifloxystrobin 5%, polyoxin 15%, naphthalenesulfonate formaldehyde condensate 4%, silkworm sand 3%, silicone compounds 0.2%, polyvinylpyrrolidone 0.8%, polyethylene glycol 1.5%, deionized water Add to 100%, mix to prepare 20% trifloxystrobin · polyoxin suspension.

Example 36 48% Trifloxystrobin · Polyoxin Suspension Concentrate

Trifloxystrobin 42%, polyoxin 6%, alkylphenol polyoxyethylene pyrimaldehyde condensate sulfate 3%, sodium dodecylbenzene sulfonate 4%, C _10-20 saturated fatty acids 0.5%, three Add 1% sodium polyphosphate, 1.5% glycerol, and deionized water to 100%, and mix to prepare a 48% trifloxystrobin·polyoxamycin suspension.

The ratio of the two active components A and B in the above embodiment can be adjusted within the synergistic range of 64:1 to 1:64 to form a new embodiment.

Application Examples Pentafloxystrobin and Jinggangmycin and their Compound Control Effects of Rice Sheath Blight

This experiment was arranged in the suburbs of Liuzhou City, Guangxi Province. The test drugs were developed and provided by Shaanxi Thompson Biotechnology Co., Ltd. The control drugs were 25% trifloxystrobin suspension concentrate (commercially available) and 10% Jinggangmycin aqueous solution (commercially available).

The disease index of rice sheath blight was investigated before the application, and the drug was applied at the early stage of the disease, and the second application was applied 10 days later. The experimental results are as follows:

Table 4 Trifloxystrobin, Jinggangmycin and their compound efficacy test for controlling rice sheath blight

It can be seen from Table 4 that the combination of trifloxystrobin and Jinggangmycin can effectively control rice sheath blight, and the control effect is better than that of a single agent. It has no adverse effect on target crops within the scope of the test drug, and has good control effect on rice blast disease, and the control effect reaches more than 90%.

Application Example Trifloxystrobin and Zhongshengmycin and their compound efficacy test for controlling banana leaf spot

This experiment was arranged in Kaiyuan County, Yunnan Province. The test drugs were developed and provided by Shaanxi Thompson Biotechnology Co., Ltd. The control drugs were 25% trifloxystrobin suspension concentrate (commercially available), 3% Zhongshengmycin WP (commercially available) .

The condition of banana leaf spot was investigated before the medicine, and the medicine was applied for the first time in the early stage of the disease, and once every 7 days, and the medicine was applied 3 times in total. The disease index was investigated 7 days and 21 days after the third application and the control effect was calculated. The experimental results are as follows:

Table 5 Trifloxystrobin, Zhongshengmycin and their compound efficacy test on controlling banana leaf spot

It can be seen from Table 5 that the combination of trifloxystrobin and Zhongshengmycin can effectively control banana leaf spot, and the control effect is better than that of a single agent. It has no adverse effect on the target crops within the scope of the test drug, and has a good control effect on apple leaf spot, and the control effect reaches more than 91%.

Application Example Seven Trifloxystrobin and kasugamycin and their compound efficacy test for controlling cucumber downy mildew

This experiment was arranged in Shunqiang County, Hebei Province. The test agents were developed and provided by Shaanxi Thompson Biotechnology Co., Ltd. The control agents were 25% trifloxystrobin suspension concentrate (commercially available) and 2% kasugamycin wettable powder (commercially available).

The disease index of cucumber downy mildew was investigated before the application, and the drug was applied at the early stage of the disease, and the second application was applied 10 days later. The experimental results are as follows:

Table 6 Trifloxystrobin, kasugamycin and their compound efficacy test on controlling cucumber downy mildew

It can be seen from Table 6 that the combination of trifloxystrobin and kasugamycin can effectively control cucumber downy mildew, and the control effect is better than that of a single agent. There is no adverse effect on the target crops within the scope of the test drug.

Application Example Schistrostrobin and polyoxin and their compound efficacy test for controlling apple powdery mildew

This experiment was arranged in Liquan County, Shaanxi Province. The test agent was developed and provided by Shaanxi Thompson Biotechnology Co., Ltd., and the control agent 25% trifloxystrobin suspension concentrate (commercially available), 3% polyoxin wettable powder (commercially available) .

The condition of apple powdery mildew was investigated before the medicine, and the medicine was applied for the first time in the early stage of the disease, and once every 7 days, for a total of 3 times. The disease index was investigated 7 days and 21 days after the third application and the control effect was calculated. The experimental results are as follows:

Table 7 Trifloxystrobin, polyoxin and their compound drug efficacy test for controlling apple powdery mildew

It can be seen from Table 7 that the combination of trifloxystrobin and polyoxin can effectively control apple powdery mildew, and the control effect is better than that of single agent. It has no adverse effect on the target crops within the scope of the test drug, and has a good control effect on apple leaf spot, and the control effect reaches more than 91%.

Claims (6)

1. the bactericidal composition containing oxime bacterium ester and antibiotic compound, composition is comprised of effective active composition and auxiliary agent, it is characterized in that: effective active composition is comprised of oxime bacterium ester and polyoxin, the ratio of weight and number of oxime bacterium ester and polyoxin is 64:1～1:64.

2. the bactericidal composition containing oxime bacterium ester and antibiotic compound according to claim 1, is characterized in that: the ratio of weight and number of oxime bacterium ester and polyoxin is 16:1～1:16.

3. the bactericidal composition containing oxime bacterium ester and antibiotic compound according to claim 2, is characterized in that: the ratio of weight and number of oxime bacterium ester and polyoxin is 8:1～1:8.

4. the bactericidal composition containing oxime bacterium ester and antibiotic compound according to claim 1, is characterized in that: wherein effective active component content accounts for 1～80% of gross weight.

5. the bactericidal composition containing oxime bacterium ester and antibiotic compound according to claim 4, is characterized in that: wherein effective active component content accounts for 5～60% of gross weight.

6. the bactericidal composition containing oxime bacterium ester and antibiotic compound according to claim 1 is for preventing and treating the application of rice blast, banded sclerotial blight, glume blight, damping off, powdery mildew, leaf spot, downy mildew, fusarium wilt, gray mold, leaf mold.