CN102675423B - 抗乙型肝炎病毒x蛋白多肽药物 - Google Patents

抗乙型肝炎病毒x蛋白多肽药物 Download PDF

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Publication number
CN102675423B
CN102675423B CN201110061855.1A CN201110061855A CN102675423B CN 102675423 B CN102675423 B CN 102675423B CN 201110061855 A CN201110061855 A CN 201110061855A CN 102675423 B CN102675423 B CN 102675423B
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polypeptide
cell
hepatitis
present
polynucleotide
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CN201110061855.1A
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Chinese (zh)
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CN102675423A (zh
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张晓东
叶丽虹
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Bio Tech Ltd Tianjin Top Tyke
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Bio Tech Ltd Tianjin Top Tyke
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Priority to CN201110061855.1A priority Critical patent/CN102675423B/zh
Priority to PCT/CN2012/072383 priority patent/WO2012122942A1/fr
Publication of CN102675423A publication Critical patent/CN102675423A/zh
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN201110061855.1A 2011-03-15 2011-03-15 抗乙型肝炎病毒x蛋白多肽药物 Active CN102675423B (zh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201110061855.1A CN102675423B (zh) 2011-03-15 2011-03-15 抗乙型肝炎病毒x蛋白多肽药物
PCT/CN2012/072383 WO2012122942A1 (fr) 2011-03-15 2012-03-15 Médicament contre la protéine x du virus de l'hépatite b utlisant un polypeptide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201110061855.1A CN102675423B (zh) 2011-03-15 2011-03-15 抗乙型肝炎病毒x蛋白多肽药物

Publications (2)

Publication Number Publication Date
CN102675423A CN102675423A (zh) 2012-09-19
CN102675423B true CN102675423B (zh) 2014-02-05

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CN201110061855.1A Active CN102675423B (zh) 2011-03-15 2011-03-15 抗乙型肝炎病毒x蛋白多肽药物

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CN (1) CN102675423B (fr)
WO (1) WO2012122942A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201400432VA (en) 2011-09-06 2014-08-28 Agency Science Tech & Res Polypeptide vaccine
CN104744564B (zh) * 2015-03-13 2017-07-28 天津托普泰克生物科技有限公司 抗乙型肝炎病毒x蛋白多肽药物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1546668A (zh) * 2003-12-12 2004-11-17 南开大学 乙型肝炎病毒x蛋白转导系统表达载体及其构建
WO2007110098A1 (fr) * 2006-03-29 2007-10-04 Institut National De La Sante Et De La Recherche Medicale PEPTIDES HBx CAPABLES DE DÉCLENCHER UNE RÉPONSE DE CELLULES CD4+ IMMUNODOMINANTES PROMISCUITAIRES DIRIGÉES CONTRE LE VHB

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Accession No:AAO27460.1;Dupont,J.等;《Genbank》;20030422;第2页序列 *
Dupont,J.等.Accession No:AAO27460.1.《Genbank》.2003,
程朋,等.TGF_1与Smad4基因在肝细胞癌中的表达及意义.《临床肿瘤学杂志》.2009,第14卷(第7期), *

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CN102675423A (zh) 2012-09-19
WO2012122942A1 (fr) 2012-09-20

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