CN103648528A - 番木瓜花叶病毒组合物及其用于刺激先天免疫应答的用途 - Google Patents

番木瓜花叶病毒组合物及其用于刺激先天免疫应答的用途 Download PDF

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Publication number: CN103648528A
Authority: CN; China
Prior art keywords: papmv; virus; compositions; purposes; vlp
Prior art date: 2011-05-13
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

CN201280023824.XA

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English (en)

Chinese (zh)

Inventor

阿兰·拉马尔

德尼·勒克莱尔

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Inst Nat de la Rech Scient

Folia Biotech Inc

Original Assignee

Folia Biotech Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-05-13

Filing date

2012-05-01

Publication date

2014-03-19

2012-05-01 Application filed by Folia Biotech Inc filed Critical Folia Biotech Inc

2014-03-19 Publication of CN103648528A publication Critical patent/CN103648528A/zh

Status Pending legal-status Critical Current

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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/10011—Arenaviridae
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/26011—Flexiviridae
- C12N2770/26023—Virus like particles [VLP]
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/26011—Flexiviridae
- C12N2770/26034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/26011—Flexiviridae
- C12N2770/26041—Use of virus, viral particle or viral elements as a vector
- C12N2770/26042—Use of virus, viral particle or viral elements as a vector virus or viral particle as vehicle, e.g. encapsulating small organic molecule
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Virology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Immunology (AREA)
Microbiology (AREA)
Mycology (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Bioinformatics & Cheminformatics (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Biotechnology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

CN201280023824.XA 2011-05-13 2012-05-01 番木瓜花叶病毒组合物及其用于刺激先天免疫应答的用途 Pending CN103648528A (zh)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US201161485955P	2011-05-13	2011-05-13
US61/485,955		2011-05-13
PCT/CA2012/050278 WO2012155261A1 (en)	2011-05-13	2012-05-01	Papaya mosaic virus compositions and uses thereof for stimulation of the innate immune response

Publications (1)

Publication Number	Publication Date
CN103648528A true CN103648528A (zh)	2014-03-19

Family

ID=47176093

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
CN201280023824.XA Pending CN103648528A (zh)	2011-05-13	2012-05-01	番木瓜花叶病毒组合物及其用于刺激先天免疫应答的用途
CN201280022947.1A Pending CN103687942A (zh)	2011-05-13	2012-05-01	病毒样颗粒及其制备方法

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
CN201280022947.1A Pending CN103687942A (zh)	2011-05-13	2012-05-01	病毒样颗粒及其制备方法

Country Status (11)

Country	Link
US (2)	US20140154288A1 (de)
EP (2)	EP2707480B1 (de)
JP (2)	JP6213461B2 (de)
CN (2)	CN103648528A (de)
AU (1)	AU2012255595A1 (de)
BR (2)	BR112013029143A2 (de)
CA (2)	CA2835967A1 (de)
DK (1)	DK2707480T3 (de)
MX (1)	MX2013013228A (de)
NO (1)	NO2800866T3 (de)
WO (2)	WO2012155261A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MX2013013228A (es)	2011-05-13	2013-12-12	Folia Biotech Inc	Particulas similares a virus y proceso para prepararlas.
MX2016003653A (es) *	2013-09-19	2016-08-11	Folia Biotech Inc	Virus de mosaico de papaya y particulas similares a virus en terapia de cancer.
WO2015153883A1 (en) *	2014-04-02	2015-10-08	Case Western Reserve University	Vaccination using plant virus particles linked to her2 antigens
US11998594B2 (en)	2014-04-02	2024-06-04	Case Western Reserve University	Anti-cancer plant virus particles linked to HER2 antigens
MA40624A (fr) *	2014-09-11	2016-03-17	Cadila Healthcare Ltd	Antigènes supérieurs du papillomavirus présentant des propriétés immunologiques supérieures et vaccin les contenant
WO2016127262A1 (en) *	2015-02-12	2016-08-18	Folia Biotech Inc.	Multimerized orthomyxovirus nucleoprotein and uses thereof
GB201708709D0 (en)	2017-06-01	2017-07-19	Univ York	Virus like particle
MX385484B (es) *	2017-06-28	2025-03-14	Univ Mexico Nac Autonoma	Vlps derivadas de virus de planta con dsrna encapsidado y metodo de sintesis.
FR3106648B1 (fr) *	2020-01-28	2022-05-27	Arkema France	Structure multicouche pour le transport ou le stockage de l’hydrogene

Citations (1)

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WO2008058396A1 (en) *	2006-11-15	2008-05-22	Folia Biotech Inc.	Papaya mosaic virus-based vaccines for influenza

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MXPA05000287A (es)	2002-07-05	2005-09-08	Leclerc Denis	Particula viral adyuvante.
EP1644034B1 (de)	2003-07-10	2011-01-12	Cytos Biotechnology AG	Zusammensetzung verpackte virusartige teilchen umfassend zur verstärkung einer immunantwort
ES2615169T3 (es)	2003-10-22	2017-06-05	Id Biomedical Corporation Of Quebec	Composiciones y procedimientos de activación de la inmunidad innata y alérgica
WO2008058369A1 (en) *	2006-11-15	2008-05-22	Folia Biotech Inc.	Immunogenic affinity-conjugated antigen systems based on papaya mosaic virus and uses thereof
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2012
- 2012-05-01 MX MX2013013228A patent/MX2013013228A/es not_active Application Discontinuation
- 2012-05-01 CA CA2835967A patent/CA2835967A1/en not_active Abandoned
- 2012-05-01 DK DK12785518.7T patent/DK2707480T3/da active
- 2012-05-01 CN CN201280023824.XA patent/CN103648528A/zh active Pending
- 2012-05-01 WO PCT/CA2012/050278 patent/WO2012155261A1/en not_active Ceased
- 2012-05-01 US US14/117,363 patent/US20140154288A1/en not_active Abandoned
- 2012-05-01 EP EP12785518.7A patent/EP2707480B1/de not_active Not-in-force
- 2012-05-01 AU AU2012255595A patent/AU2012255595A1/en not_active Abandoned
- 2012-05-01 WO PCT/CA2012/050279 patent/WO2012155262A1/en not_active Ceased
- 2012-05-01 US US14/117,365 patent/US9833504B2/en active Active
- 2012-05-01 EP EP12786315.7A patent/EP2707027A4/de not_active Withdrawn
- 2012-05-01 CN CN201280022947.1A patent/CN103687942A/zh active Pending
- 2012-05-01 JP JP2014509577A patent/JP6213461B2/ja not_active Expired - Fee Related
- 2012-05-01 JP JP2014509576A patent/JP6093926B2/ja not_active Expired - Fee Related
- 2012-05-01 CA CA2835972A patent/CA2835972A1/en not_active Abandoned
- 2012-05-01 BR BR112013029143A patent/BR112013029143A2/pt not_active IP Right Cessation
- 2012-05-01 BR BR112013029144A patent/BR112013029144A2/pt not_active IP Right Cessation
2013
- 2013-01-04 NO NO13700794A patent/NO2800866T3/no unknown

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Also Published As

Publication number	Publication date
US9833504B2 (en)	2017-12-05
EP2707480A4 (de)	2015-01-07
EP2707480B1 (de)	2017-08-02
WO2012155261A1 (en)	2012-11-22
EP2707027A4 (de)	2015-06-03
CN103687942A (zh)	2014-03-26
JP6213461B2 (ja)	2017-10-18
DK2707480T3 (da)	2017-11-13
BR112013029143A2 (pt)	2017-07-11
US20140255439A1 (en)	2014-09-11
CA2835967A1 (en)	2012-11-22
AU2012255595A1 (en)	2013-12-12
US20140154288A1 (en)	2014-06-05
BR112013029144A2 (pt)	2017-07-11
EP2707027A1 (de)	2014-03-19
WO2012155262A1 (en)	2012-11-22
NO2800866T3 (de)	2018-04-14
CA2835972A1 (en)	2012-11-22
JP2014519817A (ja)	2014-08-21
JP6093926B2 (ja)	2017-03-15
MX2013013228A (es)	2013-12-12
EP2707480A1 (de)	2014-03-19
JP2014514350A (ja)	2014-06-19

Legal Events

Date	Code	Title	Description
2014-03-19	PB01	Publication
2014-03-19	PB01	Publication
2014-06-11	C10	Entry into substantive examination
2014-06-11	SE01	Entry into force of request for substantive examination
2016-09-14	C41	Transfer of patent application or patent right or utility model
2016-09-14	TA01	Transfer of patent application right	Effective date of registration: 20160822 Address after: Quebec Applicant after: FOLIA BIOTECH Inc. Address before: Quebec Applicant before: FOLIA BIOTECH INC. Applicant before: INST NAT DE LA RECH SCIENT Effective date of registration: 20160822 Address after: Quebec Applicant after: FOLIA BIOTECH Inc. Applicant after: INST NAT DE LA RECH SCIENT Address before: Quebec Applicant before: FOLIA BIOTECH INC. Applicant before: ALAIN.LAMARRE
2020-01-17	RJ01	Rejection of invention patent application after publication	Application publication date: 20140319
2020-01-17	RJ01	Rejection of invention patent application after publication

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US20180250602A1 (en)	2018-09-06	Papaya mosaic virus compositions and uses thereof for stimulation of the innate immune response
CA2542777A1 (en)	2005-05-12	Stabilised compositions
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