CN103702681A - 用于治疗脂肪沉积的方法 - Google Patents

用于治疗脂肪沉积的方法 Download PDF

Info

Publication number
CN103702681A
CN103702681A CN201280035860.8A CN201280035860A CN103702681A CN 103702681 A CN103702681 A CN 103702681A CN 201280035860 A CN201280035860 A CN 201280035860A CN 103702681 A CN103702681 A CN 103702681A
Authority
CN
China
Prior art keywords
botulinum toxin
compositions
patient
treatment
injection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201280035860.8A
Other languages
English (en)
Chinese (zh)
Inventor
K·策尔诺克
K·马丁内兹
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allergan Inc
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of CN103702681A publication Critical patent/CN103702681A/zh
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886Metalloendopeptidases (3.4.24), e.g. collagenase
    • A61K38/4893Botulinum neurotoxin (3.4.24.69)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/06Preparations for care of the skin for countering cellulitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/91Injection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Birds (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN201280035860.8A 2011-07-20 2012-07-19 用于治疗脂肪沉积的方法 Pending CN103702681A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161509700P 2011-07-20 2011-07-20
US61/509,700 2011-07-20
PCT/US2012/047405 WO2013013042A1 (en) 2011-07-20 2012-07-19 Botulinum toxins for use in a method for treatment of adipose deposits

Publications (1)

Publication Number Publication Date
CN103702681A true CN103702681A (zh) 2014-04-02

Family

ID=46601917

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280035860.8A Pending CN103702681A (zh) 2011-07-20 2012-07-19 用于治疗脂肪沉积的方法

Country Status (12)

Country Link
US (1) US20140127188A1 (2)
EP (1) EP2734224A1 (2)
JP (1) JP2014520892A (2)
KR (1) KR20140082956A (2)
CN (1) CN103702681A (2)
AU (1) AU2012283968B2 (2)
BR (1) BR112014001066A2 (2)
CA (1) CA2841955A1 (2)
IN (1) IN2014DN00254A (2)
MX (1) MX2014000612A (2)
RU (1) RU2014103543A (2)
WO (1) WO2013013042A1 (2)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9486408B2 (en) 2005-12-01 2016-11-08 University Of Massachusetts Lowell Botulinum nanoemulsions
US9655926B1 (en) 2013-08-23 2017-05-23 Amiya Prasad Treatment for hair thinning and hair loss
WO2016021985A1 (ko) * 2014-08-07 2016-02-11 김상덕 보툴리눔 독소와 공기의 혼합물을 포함하는 안면 윤곽 교정용 조성물 및 이를 이용한 안면 윤곽 교정 방법
TWI722077B (zh) 2015-12-18 2021-03-21 中國大陸商江蘇南大光電材料股份有限公司 製造有機胺基矽烷之方法;自該有機胺基矽烷製造矽烷胺之方法
EP3541358A1 (en) 2016-11-21 2019-09-25 Eirion Therapeutics, Inc. Transdermal delivery of large agents
JP2020520917A (ja) * 2017-05-18 2020-07-16 ルバンス セラピュティックス インク.Revance Therapeutics,Inc. 頸部ジストニアの治療方法
US20190030118A1 (en) * 2017-07-27 2019-01-31 Ipsen Biopharm Limited Treatment of lower limb spasticity

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070128228A1 (en) * 2004-09-03 2007-06-07 Allergan, Inc. Buttock deformity treatment
CN101835449A (zh) * 2007-08-31 2010-09-15 Dsmip资产有限公司 4-脒基苄胺用于美容和/或皮肤病学的用途

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9120306D0 (en) 1991-09-24 1991-11-06 Graham Herbert K Method and compositions for the treatment of cerebral palsy
US5437291A (en) 1993-08-26 1995-08-01 Univ Johns Hopkins Method for treating gastrointestinal muscle disorders and other smooth muscle dysfunction
US6974578B1 (en) 1993-12-28 2005-12-13 Allergan, Inc. Method for treating secretions and glands using botulinum toxin
US5766605A (en) 1994-04-15 1998-06-16 Mount Sinai School Of Medicine Of The City University Of New York Treatment of autonomic nerve dysfunction with botulinum toxin
EP1086702B1 (en) 1994-05-09 2005-04-13 BINDER, William J. Presynaptic neurotoxins for treatment of migraine headache
US5670484A (en) 1994-05-09 1997-09-23 Binder; William J. Method for treatment of skin lesions associated with cutaneous cell-proliferative disorders
GB9508204D0 (en) 1995-04-21 1995-06-07 Speywood Lab Ltd A novel agent able to modify peripheral afferent function
DE69841291D1 (de) 1997-07-15 2009-12-31 Univ Colorado Verwendung von Botulinumtoxin zur Behandlung der renitenten Blasenentleerungsstörung
US6063768A (en) 1997-09-04 2000-05-16 First; Eric R. Application of botulinum toxin to the management of neurogenic inflammatory disorders
US6113915A (en) 1999-10-12 2000-09-05 Allergan Sales, Inc. Methods for treating pain
US6265379B1 (en) 1999-10-13 2001-07-24 Allergan Sales, Inc. Method for treating otic disorders
US6139845A (en) 1999-12-07 2000-10-31 Allergan Sales, Inc. Method for treating cancer with a neurotoxin
US6143306A (en) 2000-01-11 2000-11-07 Allergan Sales, Inc. Methods for treating pancreatic disorders
US6358513B1 (en) 2000-02-15 2002-03-19 Allergan Sales, Inc. Method for treating Hashimoto's thyroiditis
US6319506B1 (en) * 2000-02-22 2001-11-20 Allergan, Sales, Inc. Method for treating hypercalcemia
US6464986B1 (en) 2000-04-14 2002-10-15 Allegan Sales, Inc. Method for treating pain by peripheral administration of a neurotoxin
US6299893B1 (en) 2000-04-17 2001-10-09 Marvin Schwartz Method to reduce hair loss and stimulate hair regrowth
US6306423B1 (en) 2000-06-02 2001-10-23 Allergan Sales, Inc. Neurotoxin implant
US6306403B1 (en) 2000-06-14 2001-10-23 Allergan Sales, Inc. Method for treating parkinson's disease with a botulinum toxin
US6423319B1 (en) 2000-10-04 2002-07-23 Allergan Sales, Inc. Methods for treating muscle injuries
EP2272340B1 (en) * 2002-08-19 2018-03-14 Ira Sanders Botulinum toxin
CA2558408C (en) * 2004-03-03 2014-11-18 Essentia Biosystems, Inc. Compositions and methods for topical application and transdermal delivery of botulinum toxins
US20060057165A1 (en) * 2004-09-10 2006-03-16 Dimitrios Dimitrakoudis Clostridium botulinum toxin formulation and method for reducing weight
US7727537B2 (en) * 2005-02-14 2010-06-01 Dpm Therapeutics Corp. Stabilized compositions for topical administration and methods of making same
US20080220021A1 (en) * 2005-02-14 2008-09-11 Pankaj Modi Topical Botulinum Toxin Compositions for the Treatment of Hyperhidrosis
CN101374498A (zh) * 2005-12-01 2009-02-25 麻萨诸塞州洛厄尔大学 肉毒杆菌纳米乳液
US20090297632A1 (en) * 2008-06-02 2009-12-03 Waugh Jacob M Device, Methods and Compositions to Alter Light Interplay with Skin
KR102080429B1 (ko) * 2008-06-26 2020-02-21 안테리오스, 인코퍼레이티드 경피 운반
AU2010220830B2 (en) * 2009-03-02 2016-07-14 Nova Scientifica Llc Medicinal cosmetic lipoatrophy

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070128228A1 (en) * 2004-09-03 2007-06-07 Allergan, Inc. Buttock deformity treatment
CN101835449A (zh) * 2007-08-31 2010-09-15 Dsmip资产有限公司 4-脒基苄胺用于美容和/或皮肤病学的用途

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
LIM等: "Botulinum toxin injections to reduce adiposity:Possibility,or fat chante?", 《MEDICAL HYPOTHESES》 *
MANSOOREH BAGHERI等: "A pilot study on lipolytic effect of subcutaneous botulinum toxin injection in rabbits", 《ANALYTICAL AND QUANTITATIVE CYTOLOGY AND HISTOLOGY》 *

Also Published As

Publication number Publication date
WO2013013042A1 (en) 2013-01-24
EP2734224A1 (en) 2014-05-28
JP2014520892A (ja) 2014-08-25
CA2841955A1 (en) 2013-01-24
US20140127188A1 (en) 2014-05-08
MX2014000612A (es) 2014-02-27
AU2012283968B2 (en) 2016-04-14
AU2012283968A1 (en) 2014-02-06
RU2014103543A (ru) 2015-08-27
BR112014001066A2 (pt) 2017-02-21
IN2014DN00254A (2) 2015-06-05
KR20140082956A (ko) 2014-07-03

Similar Documents

Publication Publication Date Title
JP6841736B2 (ja) ボツリヌス菌ナノエマルジョン
JP6092205B2 (ja) 性的行為に関連した失禁の治療方法
US10420823B2 (en) Method for treating premature ejaculation with a botulinum neurotoxin
US10245305B2 (en) Botulinum toxin therapy for skin disorders
AU2012283968B2 (en) Botulinum toxins for use in a method for treatment of adipose deposits
US20060182766A1 (en) Stabilized protein compositions for topical administration and methods of making same
JP2009539948A (ja) 少なくとも1種のボツリヌス神経毒素及び少なくとも1種の鎮静剤誘導体の、治療上の、同時、分離、又は、順次的な使用
BRPI0417493B1 (pt) uso de uma toxina botulínica para tratamento de distúrbios da pele
CN101355962A (zh) 减少非毒素蛋白质的肉毒杆菌毒素组合物和其局部施用及透皮递送方法
KR20070057908A (ko) 보툴리눔 독소를 사용한 튼살의 처치방법
EP1853303A1 (en) Stabilized compositions for topical administration and methods of making same
US8697090B2 (en) Method of treating persistent genital arousal disorder with a neurotoxin
KR101234459B1 (ko) 보툴리눔 독소를 사용한 둔부 변형의 처치방법
HK1240854A1 (en) Injectable botulinum toxin formulations
HK1162925A (en) Injectable botulinum toxin formulations

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20140402