CN106188281B - 抗诺如病毒gii.4型鼠源单克隆抗体的制备和应用 - Google Patents

抗诺如病毒gii.4型鼠源单克隆抗体的制备和应用 Download PDF

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Publication number
CN106188281B
CN106188281B CN201510216744.1A CN201510216744A CN106188281B CN 106188281 B CN106188281 B CN 106188281B CN 201510216744 A CN201510216744 A CN 201510216744A CN 106188281 B CN106188281 B CN 106188281B
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antibody
seq
present
gii
monoclonal antibody
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CN106188281A (zh
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黄忠
王晓黎
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Shanghai Institute Of Immunology And Infection Chinese Academy Of Sciences
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Institut Pasteur of Shanghai of CAS
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Priority to PCT/CN2016/080793 priority patent/WO2016173558A1/fr
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN201510216744.1A 2015-04-30 2015-04-30 抗诺如病毒gii.4型鼠源单克隆抗体的制备和应用 Expired - Fee Related CN106188281B (zh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201510216744.1A CN106188281B (zh) 2015-04-30 2015-04-30 抗诺如病毒gii.4型鼠源单克隆抗体的制备和应用
PCT/CN2016/080793 WO2016173558A1 (fr) 2015-04-30 2016-04-29 Préparation et utilisation d'un anticorps monoclonal murin de type anti-norovirus gii.4

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201510216744.1A CN106188281B (zh) 2015-04-30 2015-04-30 抗诺如病毒gii.4型鼠源单克隆抗体的制备和应用

Publications (2)

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CN106188281A CN106188281A (zh) 2016-12-07
CN106188281B true CN106188281B (zh) 2019-10-08

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CN (1) CN106188281B (fr)
WO (1) WO2016173558A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108727488B (zh) * 2017-04-13 2022-07-22 中国科学院上海巴斯德研究所 抗诺如病毒gii.17单克隆抗体的制备和应用
CN109081868B (zh) * 2017-06-14 2022-06-24 中国科学院上海巴斯德研究所 靶向寨卡病毒包膜蛋白保守表位的单克隆抗体及其应用
CN109957014B (zh) * 2017-12-25 2022-03-29 中国科学院上海巴斯德研究所 抗诺如病毒gii.3鼠源单克隆抗体的制备和应用
CN109265542B (zh) * 2018-09-27 2021-06-15 国药中生生物技术研究院有限公司 特异性结合诺如病毒gii.4基因型vp1蛋白或vlp的抗体及其制备方法和应用
CN109734801A (zh) * 2019-03-15 2019-05-10 南方医科大学 一种gii.4型诺如病毒广谱单克隆抗体的制备方法及用途
CN110221080B (zh) * 2019-06-25 2021-09-17 上海交通大学 一种人源诺如病毒免疫胶体金试剂盒及细胞株
CN112159797B (zh) * 2020-09-18 2022-08-05 广东省微生物研究所（广东省微生物分析检测中心） 杂交瘤细胞株3g7 1b10、抗gii.4型诺如病毒p蛋白单克隆抗体和应用
CN112175912B (zh) * 2020-09-18 2022-07-29 广东省微生物研究所（广东省微生物分析检测中心） 杂交瘤细胞株3g4 1d6、抗gii.4型诺如病毒p蛋白单克隆抗体和应用
JP2024503274A (ja) * 2020-12-30 2024-01-25 遠大賽威信生命科学（南京）有限公司 ノロウイルスのウイルス様粒子、免疫組成物又はキット及びその用途
CN115894672B (zh) * 2022-10-26 2025-12-16 天津智鼎生物科技有限公司 一种针对诺如病毒gⅱ基因型vp1蛋白的单克隆抗体及其应用
CN116948020B (zh) * 2023-08-28 2025-09-26 上海交通大学 一种广谱识别人源诺如病毒的可溶性单链抗体及制备方法
CN119161469B (zh) * 2024-08-20 2025-09-26 苏州东抗生物科技有限公司 一种抗诺如病毒的单克隆抗体及其应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014126921A1 (fr) * 2013-02-12 2014-08-21 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Anticorps monoclonaux neutralisant les norovirus
CN104098698A (zh) * 2013-04-08 2014-10-15 中国人民解放军第二军医大学 一种抗cd3抗体及其制法和应用

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014126921A1 (fr) * 2013-02-12 2014-08-21 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Anticorps monoclonaux neutralisant les norovirus
CN104098698A (zh) * 2013-04-08 2014-10-15 中国人民解放军第二军医大学 一种抗cd3抗体及其制法和应用

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Prevalence of norovirus GII-4 antibodies in Finnish children;Nurminen K 等;《J Med Virol》;20110331;第83卷(第3期);第525-531页 *
诺如病毒衣壳蛋白单克隆抗体的制备及鉴定;郭丽 等;《中国人兽共患病学报》;20060531;第22卷(第5期);第414-418页 *

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WO2016173558A1 (fr) 2016-11-03

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Address after: Building 2, No. 225, Chongqing South Road, Huangpu District, Shanghai, 200025

Patentee after: Shanghai Institute of Immunology and Infection, Chinese Academy of Sciences

Address before: No. 411, Hefei Road, Huangpu District, Shanghai 200025

Patentee before: INSTITUT PASTEUR OF SHANGHAI, CHINESE ACADEMY OF SCIENCES

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Granted publication date: 20191008