CN106561663A - Pesticide composition containing picloram and bispyribac sodium, and application thereof - Google Patents

Abstract

The invention discloses a pesticide composition containing amiloride and bispyribac and its application. The active ingredients of the pesticide composition are amiloride and bispyribac, and the quality of amiloride and bispyribac The ratio is 50‑250:0.5‑10. The pesticide composition shows obvious synergistic effect on Asteroides japonicus within the above-mentioned proportioning range, reduces the dosage of pesticides, reduces the frequency of medication, reduces the cost of pesticides, and reduces the adverse effects of pesticides on the ecological environment; The combination of these active ingredients can effectively control the spreading hazards and regeneration ability of A. japonicus, and make up for the defects and limitations of single-agent use; prolonging the service life of the agents is of great significance to the comprehensive management of A. japonicus. The combined effect of the two can be quickly exerted, and the duration of effect is long, and the cost of use is low, so it can be used to prevent and control Aurantia chinensis.

Description

A kind of pesticide composition containing amiloride and bispyribac and its application

technical field

The invention belongs to the technical field of pesticides, and in particular relates to a pesticide composition containing amiloride and bispyribac, which is used for preventing and controlling Aquaphyllum japonicus.

Background technique

Once it is introduced into suitable growing areas lacking effective natural enemies, it will expand and spread extremely fast, and it can invade the surrounding waters and wetlands in a short period of time, forming a large area of single plant communities, and seriously damaging the local ecological environment. Biodiversity, triggering ecological disaster. In our country, Alpinia sinensis has invaded river courses, ponds, fish ponds, lakes, and farmland, seriously affecting shipping, irrigation, aquaculture, agricultural production, and the ecological environment. At present, methods such as artificial or mechanical fishing and spraying herbicides are mostly used for the control of A. Manual or mechanical fishing is labor-intensive and costly, and most herbicides are only effective on the above-ground part of the hollow lotus grass, and it is difficult to inhibit its regeneration ability. Repeated use of pesticides increases the cost of control and aggravates the impact on the environment and ecology. It is particularly important to study and screen high-efficiency and safe herbicide formulations that can effectively control the damage of A. japonicus throughout the year after one-time use.

Amiloride, chemical name: 4-amino-3,5,6-trichloropyridinecarboxylic acid, is a synthetic hormone herbicide (plant growth regulator). Absorbed quickly through plant leaves and roots, it induces epistasis in sensitive plants (such as stimulating cell elongation and senescence, especially in the meristem area), and eventually causes plant growth stagnation and rapid death. Amiloride can be used to control broad-leaved weeds in rice fields, but has no phytotoxic effect on gramineous crops.

Bispyribac, chemical name: 2,6-bis(4,6-dimethoxypyrimidine-2-oxy)sodium benzoate, is a pyrimidine salicylic acid herbicide, which mainly prevents branched-chain amino acids from being absorbed by roots and stems and leaves Biosynthesis of the role of selective pre-emergence, post-emergence herbicide. Bispyribac can be used to control annual and perennial weeds in rice fields, and has the advantages of high efficiency and broad spectrum.

Invention content:

Purpose of the invention: Aiming at the problems in the prior art that the control effect on A. japonicus is poor, and it is difficult to effectively inhibit the spread and damage of A. japonicus and its regeneration in one use, the present invention aims to provide a kind of medicine containing amiloride and bispyribac. The pesticide composition makes it have the characteristics of high efficiency, broad spectrum, environmental friendliness, and benefit for the control of the lotus seedlings. Another object of the present invention is to provide an application of the aforementioned pesticide composition containing amiloride and bispyribac.

Technical solution: In order to realize the above-mentioned purpose of the invention, the technical solution adopted in the present invention is:

A pesticide composition containing amiloride and bispyribac, the active ingredients are amiloride and bisfluben, and the mass ratio of amiloride to bispyribac is 50-250:0.5-10.

The preferred mass ratios of amiloride and bisfluben are 60:1, 120:2, 180:4 and 240:8.

A pesticide preparation containing amiloride and bispyribac, said preparation is prepared from a pesticide composition containing amiloride and bispyribac and adjuvants acceptable in the field of pesticide preparations to any pesticide acceptable dosage form.

The dosage form of the pesticide preparation is wettable powder, water dispersible granule, suspension or oil suspension.

The two herbicidal active ingredients in the pesticide formulation account for 1-90% of the total weight of the pesticide formulation.

The auxiliary material is selected from wetting agent, dispersant, spreading agent, stabilizer, penetrating agent, thickener, antifreeze agent, defoamer, filler, solvent; wherein, the wetting agent is dodecylbenzene Sodium sulfonate, calcium dodecylbenzenesulfonate, sodium lauryl sulfate, lignosulfonate, alkylphenol formaldehyde resin polyoxyethylene ether, fatty alcohol sulfate, phenylethylphenol polyoxyethylene ether, One or more of nonylphenol polyoxyethylene ethers; the dispersant is lignosulfonate, alkylbenzenesulfonate, alkylphenol polyoxyethylene ether, nonylphenol polyoxyethylene ether, alkane One or more of ethyl ethyl sulfonate, alkyl naphthalene sulfonate formaldehyde condensate and polycarboxylate; the stabilizer is one or more of epoxidized vegetable oil; the exhibit The colorant is one or more of polyvinyl alcohol, sodium alkyl diphenyl ether disulfonate, polytrisiloxane, triethanolamine oleate; the solvent is soybean oil, methyl oleate, white oil, One or more of turpentine, methylnaphthalene, and higher aliphatic hydrocarbon oils; the filler is one or more of white carbon black, corn starch, kaolin, diatomaceous earth, sodium sulfate, and ammonium sulfate.

The application of the pesticide composition containing amiloride and bispyribac in the prevention and treatment of Asteroides spinosa. When preventing and treating Abyssiniana, use it at the initial stage, vigorous growth stage, flowering stage, and late growth stage of Abyssiniana.

The production processes of various application dosage forms of the pesticide composition containing amiloride and bispyribac all belong to the prior art.

The pesticide composition containing amiloride and bispyribac and its pesticide preparation provided by the present invention are usually used by spraying, and other agricultural application techniques can also be used as required.

Beneficial effects: Compared with the prior art, the pesticide composition containing amiloride and bispyribac of the present invention has the following advantages:

(1) The pesticide composition containing amiloride and bispyribac of the present invention shows obvious synergistic effect within a certain ratio range, and the control effect of the composition is significantly improved compared with that of a single agent, reducing the amount of pesticide The use dosage is lower, the frequency of medication is reduced, the cost of medication is reduced, and the adverse effects of pesticides on the ecological environment are reduced.

(2) The pesticide composition containing amiloride and bispyribac of the present invention, the combination of the two active ingredients, can effectively control the spread, damage and regeneration of A. japonicus, and make up for the defects and limitations of single-dose use sex.

(3) The pesticide composition containing amiloride and bispyribac of the present invention has rapid drug effect, long duration, low use cost, convenient use, time-saving and labor-saving, and its popularization and application has huge economic benefits and social benefits.

Specific implementation plan:

The present invention will be further described below in conjunction with specific examples. The following descriptions are only preferred embodiments of the present invention, and are only used to describe the present invention, and should not be construed as limiting the scope of the present invention. It should be noted that any modifications, equivalent replacements and improvements made within the spirit and principles of the present invention shall be included within the protection scope of the present invention.

In the following examples, unless otherwise specified, all percentages are percentages by weight.

Example 1: 30.5% amiloride bispyribac water dispersible granules

The components of the pesticide composition containing amiloride and bispyribac are: 30% of amiloride, 0.5% of bispyribac, 4% of sodium lauryl sulfate, 5% of carboxylates, and 10% of urea %, add kaolin to 100%.

After amiloride is adsorbed and mixed with the filler, it is added to the conical mixer together with other above-mentioned materials and mixed evenly, and then pulverized by the jet mill, and the pulverized material is then mixed by the conical mixer, and the fineness of the mixed material is 98% pass through a 325-mesh standard sieve, put into a kneader to knead into a plastic material, and finally put this material into an extrusion granulator to extrude and granulate, after granulation, dry and sieve to obtain 30.5% amlopyridine Acid · bispyribac water dispersible granules.

Example 2: 18.4% amiloride bispyribac suspension concentrate

The components of the pesticide composition containing amiloride and bispyribac are: 18% amiloride, 0.4% bispyribac, 5% phenethylphenol polyoxyethylene ether, and 8% sodium lignosulfonate , ethylene glycol 5%, magnesium aluminum silicate 2%, defoamer 0.5%, preservative 0.1%, xanthan gum 0.1%, water to 100%.

After amiloride is adsorbed and mixed with the filler, other above-mentioned materials (except xanthan gum) are added to the reactor mixer together, stirred evenly, and the materials are injected into a multi-stage sand mill for grinding, and the ground materials are fine 98% pass through 1-5um and discharge. The material is put into a high-shear emulsification kettle together with xanthan gum dissolved in advance. After emulsification, 18.4% amiloride bispyribac suspending agent can be made.

Example 3: 30.6% amiloride bispyribac oil suspension concentrate

The components of the pesticide composition containing amiloride and bispyribac are: 30% of amiloride, 0.6% of bispyribac, 5% of phenethylphenol polyoxyethylene ether, and 8% of sodium lignosulfonate , epoxidized soybean oil 5%, organic bentonite 5%, methyl oleate to 100%.

After amiloride is adsorbed and mixed with the filler, other above-mentioned materials (except organic bentonite) are added to the reactor mixer together, stirred evenly, and the materials are injected into a multi-stage sand mill for grinding. The fineness of the ground materials is After 98% pass through 1-5um, the material is discharged, and the material is put into a high-shear emulsification kettle together with the pre-dissolved organic bentonite. After emulsification, a 30.6% amclopyral-bispyribac oil suspension can be made.

Example 4: 24.6% amiloride · bispyribac wettable powder

The components of the pesticide composition containing amiloride and bispyribac are: 24% amiloride, 0.6% bispyribac, 2% sodium lauryl sulfate, 3% sodium butylnaphthalenesulfonate, Calcium lignosulfonate 5%, white carbon black 5%, kaolin to 100%.

After amiloride is adsorbed and mixed with the filler, it is added to the conical mixer together with other above-mentioned materials and mixed evenly, and then pulverized by the jet mill, and the pulverized material is then mixed by the conical mixer, and the fineness of the mixed material is 98% passed through a 325-mesh standard sieve to obtain a 24.6% amiloride bispyribac wettable powder.

Example 5: 6.8% amiloride·bispyribac water-dispersible granules

The components of the pesticide composition containing amiloride and bispyribac are: 6% amiloride, 0.8% bispyribac, 4% sodium lauryl sulfate, 5% carboxylate, urea 10% %, add kaolin to 100%.

After amiloride is adsorbed and mixed with the filler, it is added to the conical mixer together with other above-mentioned materials and mixed evenly, and then pulverized by the jet mill, and the pulverized material is then mixed by the conical mixer, and the fineness of the mixed material is 98% pass through a 325-mesh standard sieve, put into a kneader to knead into a plastic material, and finally put the material into an extrusion granulator to extrude and granulate, after granulation, dry and sieve to obtain 6.8% amlopyridine Acid · bispyribac water dispersible granules.

Example 6: 12.4% amiloride-bispyribac suspension concentrate

The components of the pesticide composition containing amiloride and bispyribac are: 12% of amiloride, 0.4% of bispyribac, 5% of phenethylphenol polyoxyethylene ether, and 8% of sodium lignosulfonate , ethylene glycol 5%, magnesium aluminum silicate 2%, defoamer 0.5%, preservative 0.1%, xanthan gum 0.1%, water to 100%.

After amiloride is adsorbed and mixed with the filler, other above-mentioned materials (except xanthan gum) are added to the reactor mixer together, stirred evenly, and the materials are injected into a multi-stage sand mill for grinding, and the ground materials are fine 98% pass through 1-5um and discharge. The material is put into a high-shear emulsification kettle together with xanthan gum dissolved in advance.

Example 7: 18.2% amiloride bispyribac oil suspension concentrate

The components of the pesticide composition containing amiloride and bispyribac are: 18% amiloride, 0.2% bispyribac, 5% phenethylphenol polyoxyethylene ether, and 8% sodium lignosulfonate , epoxidized soybean oil 5%, organic bentonite 5%, methyl oleate to 100%.

After amiloride is adsorbed and mixed with the filler, other above-mentioned materials (except organic bentonite) are added to the reactor mixer together, stirred evenly, and the materials are injected into a multi-stage sand mill for grinding. The fineness of the ground materials is After 98% pass through 1-5um, the material is discharged, and the material is put into a high-shear emulsification kettle together with the pre-dissolved organic bentonite, and after emulsification, the 18.2% amclopyral-bispyribac oil suspension concentrate can be made.

Example 8: 24.1% amiloride bispyribac wettable powder

The components of the pesticide composition containing amiloride and bispyribac are: 24% amiloride, 0.1% bispyribac, 2% sodium lauryl sulfate, 3% sodium butylnaphthalenesulfonate, Calcium lignosulfonate 5%, white carbon black 5%, kaolin to 100%.

After amiloride is adsorbed and mixed with the filler, it is added to the conical mixer together with other above-mentioned materials and mixed evenly, and then pulverized by the jet mill, and the pulverized material is then mixed by the conical mixer, and the fineness of the mixed material is A 24.1% amiloride-bispyribac wettable powder was obtained by passing 98% of the powder through a 325-mesh standard sieve.

Example 9 Screening of the optimal ratio of amiloride and bispyribac

In order to further understand the joint effect of the mixture of amiloride and bispyribac on Azalea chinensis, the inventors conducted a formula screening test on the mixture of amiloride and bispyribac.

Experimental material: Alpinia sinensis, collected from the leisure field of Jiangsu Academy of Agricultural Sciences in April 2015.

Test equipment: PWT-510 spray tower, Mettler AB135-S electronic balance, volumetric flask, triangular flask, beaker, measuring cylinder, plastic bucket, pipette, ruler, scissors, etc.

Test method: first weigh a certain amount of amiloride and bispyribac, add methanol to fully dissolve, then dilute with 0.1% Tween 80 aqueous solution to a fixed volume of 100mL to prepare a single dose of mother solution, and set the amount according to the pre-experiment Take different volumes of mother liquor. Take a plastic bucket (upper diameter 23cm, lower diameter 16cm, height 20cm) and fill it with air-dried fine soil. The soil is horse liver soil, pH 6.7, organic matter content 1.6%, air-dried and sieved for later use. Cut about 5 stem nodes (3 to 4 pairs of leaves, with adventitious roots) of the hollow lotus seedlings and plant them in plastic buckets (upper diameter 23 cm, lower diameter 16 cm, height 20 cm) filled with fine soil and cultivated in a solar greenhouse (temperature is 33°C/25°C, about 12h light/12h dark). When 8 to 10 pairs of leaves of A. japonicus are sprayed in the PWT-510 spray tower according to the experimental design dosage (accurate spray area is 0.2m ² , spray liquid is 10ml, spray volume is 500L/hm ² , spray pressure 0.5kpa) to apply the agent. After spraying, put it outdoors for 2 hours, then place it in a solar greenhouse for cultivation, and spray it with water as a control treatment.

Regularly observe the growth of the lotus seedlings after the medicine. 25 days after application, the fresh weight of the upper part of the lotus meadow was investigated, and the inhibition rate of the fresh weight of the above-ground part was calculated. 45 days after application (that is, 20 days after the above-ground part was cut off), the number of regenerated branches of A. japonicus was investigated, and the inhibition rate was calculated. The DPS data processing system was used to obtain the toxicity regression equation of a single dose of amiloride, bispyribac and 8 binary mixtures, and calculate the ED ₅₀ value and 95% confidence limit. The co-toxicity coefficient was calculated by Sun Yunpei's method (the co-toxicity coefficient greater than 120 represents the synergistic effect, less than 80 represents the antagonistic effect, and between 80 and 120 represents the additive effect).

Test results: After 20 days of post-drug treatment, after the application of amclopyralid: bispyribac at a ratio of 50-250:0.5-10, the leaves of A. japonicus became yellow and curled, and the inhibition rate increased with the increase of the concentration of the drug. It showed an upward trend, and it had high biological activity to A. japonicus.

Twenty-five days after treatment, the 8 binary combinations of amiloride and bispyribac had obvious inhibitory effects on the fresh weight of A. japonicus (Table 1). The co-toxicity coefficients of the eight ratios of 50:0.5, 50:10, 250:0.5, 250:10, 60:1, 120:2, 180:4, and 240:8 were 145.40, 256.05, 167.79, and 214.34, respectively , 155.71, 224.78, 193.22, 282.93. The co-toxicity coefficient is greater than 120, showing a synergistic effect (Table 1).

Table 1 The combined effect of the mixture of clopyralid and bispyribac on the fresh weight of A. chinensis

The eight binary combinations of amiloride and bispyribac had obvious inhibitory effects on the number of regenerated shoots of A. japonicus (Table 1). The co-toxicity coefficients of the eight ratios of 50:0.5, 50:10, 250:0.5, 250:10, 60:1, 120:2, 180:4, and 240:8 were 179.68, 187.66, 197.82, and 270.23, respectively , 248.31, 219.77, 247.64, 178.10. The co-toxicity coefficient is greater than 120, showing a synergistic effect (Table 2).

Table 2 The combined effect of the mixture of clopyralid and bispyribac on the number of regenerated branches of A.

Amclopyralid can inhibit cell division and growth, and is mainly used in rapeseed fields. It has special effects on perennial weeds such as legumes and Compositae, and has a long-lasting effect; bispyribac has better effects on various annual and perennial weeds. Inhibitory effect, effective speed. The mixture of amclopyral and bispyribac can effectively inhibit the spreading damage and regeneration ability of A. japonicus. The mixture of amiloride and bispyribac at a mass ratio of 50-250:0.5-10 exhibits a synergistic effect on A. japonicus.

Embodiment 10 field efficacy test

Test agent: choose the mixed herbicides prepared in Examples 1-4.

Control drug: 10% bispyribac ether suspension concentrate (commercially available)

240g/L amiloride aqueous solution (commercially available)

set water control

Method of use: Spray the lotus seedlings during the vigorous growth period, and the amount of liquid medicine is 30kg/mu.

Application time: Refer to the Ministry of Agriculture's "Pesticide Field Efficacy Test Guidelines" on August 17, 2015, and apply according to the designed dose.

Investigation objects and methods: A. japonicus. The fresh weight of A. japonicus was investigated 30 days after application. The test results and analysis are shown in Table 3, respectively.

Table 3 Field efficacy test results (after 30d)

treatment agent Consumption (g/667m ² ) Fresh weight control effect (%) Example 1 300 88.67 Example 2 500 89.13 Example 3 400 91.10 Example 4 500 90.56 10% bispyribac ether suspension concentrate 35 63.94 240g/L Amiloride water solution 600 68.42

Example 11

With reference to the method of Example 10, the mixed herbicides prepared in Examples 5-8 were carried out to the field drug efficacy test, and it was confirmed that each mixed herbicide had obvious synergistic effect, and had significant control effect on A. Significantly better than single-dose use, and long-lasting.

Claims (9)

1. A pesticide composition containing amiloride and bispyribac, characterized in that: the active ingredients are amiloride and bisfluben, and the mass ratio of amiloride to bispyribac is 50-250: 0.5-10. 2. A pesticide formulation containing amiloride and bispyribac, characterized in that: said formulation is acceptable in the field of pesticide formulations and pesticide formulations containing amiloride and bispyribac according to claim 1 The excipients are formulated into any dosage form acceptable to pesticides. 3. The pesticide preparation containing amiloride and bispyribac according to claim 2, characterized in that: the dosage form of the pesticide preparation is wettable powder, water dispersible granule, suspending agent, microemulsion, oil preparation , suspoemulsion, emulsifiable concentrate, water emulsion or oil suspension. 4. The pesticide formulation containing amiloride and bispyribac according to claim 2, wherein the active ingredient in the formulation accounts for 1-90% of the weight of the formulation. 5. The pesticide formulation containing amiloride and bispyribac according to claim 2, characterized in that: said adjuvant is selected from the group consisting of wetting agent, dispersant, spreading agent, stabilizer, penetrating agent, thickening agent agent, antifreeze, defoamer, filler, solvent; wherein, the wetting agent is sodium dodecylbenzenesulfonate, calcium dodecylbenzenesulfonate, sodium dodecylsulfate, lignosulfonic acid One or more of salt, alkylphenol formaldehyde resin polyoxyethylene ether, fatty alcohol sulfate, phenethylphenol polyoxyethylene ether, nonylphenol polyoxyethylene ether; the dispersant is lignosulfonic acid Salt, alkylbenzenesulfonate, alkylphenol polyoxyethylene ether, nonylphenol polyoxyethylene ether, alkylethylsulfonate, alkylnaphthalenesulfonate formaldehyde condensate and polycarboxylate one or more kinds; the stabilizer is one or more kinds of epoxidized vegetable oil; the spreading agent is polyvinyl alcohol, sodium alkyl diphenyl ether disulfonate, polytrisiloxane, oil One or more in acid triethanolamine; Described solvent is one or more in soybean oil, methyl oleate, white oil, turpentine methylnaphthalene higher aliphatic hydrocarbon oil; Described filler is white carbon black, One or more of corn starch, kaolin, diatomaceous earth, sodium sulfate, ammonium sulfate. 6. The application of the pesticide composition containing amiloride and bispyribac according to claim 1 in the prevention and treatment of Nitonia chinensis. 7 . The application according to claim 6 , characterized in that: when preventing and controlling A. japonicus, it is used in the initial stage, vigorous growth stage or flowering stage of A. japonicus. 8. The application of the pesticide preparation containing amiloride and bispyribac according to any one of claims 2-5 in the prevention and treatment of Nitonia chinensis. 9. The pesticide composition containing amiloride and bispyribac according to claim 1, characterized in that: the mass ratio of amiloride to bispyribac is 60:1, 120:2, 180 :4, 240:8, 60:8, 120:4, 180:2 and 240:1.