CN106823846A - 分子分离装置 - Google Patents

分子分离装置 Download PDF

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Publication number: CN106823846A
Authority: CN; China
Prior art keywords: film; hole; room; water slurry; seperation
Prior art date: 2012-03-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

CN201710120140.6A

Other languages

English (en)

Chinese (zh)

Inventor

小约翰·B·斯特森

莎拉·西蒙

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Lockheed Martin Corp

Original Assignee

Lockheed Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2012-03-21

Filing date

2013-03-20

Publication date

2017-06-13

2013-03-20 Application filed by Lockheed Corp filed Critical Lockheed Corp

2017-06-13 Publication of CN106823846A publication Critical patent/CN106823846A/zh

Status Pending legal-status Critical Current

Links

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Classifications

- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
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- C07K1/14—Extraction; Separation; Purification
- C07K1/24—Extraction; Separation; Purification by electrochemical means
- C07K1/26—Electrophoresis
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D35/00—Filtering devices having features not specifically covered by groups B01D24/00 - B01D33/00, or for applications not specifically covered by groups B01D24/00 - B01D33/00; Auxiliary devices for filtration; Filter housing constructions
- B01D35/06—Filters making use of electricity or magnetism
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D57/00—Separation, other than separation of solids, not fully covered by a single other group or subclass, e.g. B03C
- B01D57/02—Separation, other than separation of solids, not fully covered by a single other group or subclass, e.g. B03C by electrophoresis
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
- B01D71/02—Inorganic material
- B01D71/021—Carbon
- B01D71/0211—Graphene or derivates thereof
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2325/00—Details relating to properties of membranes
- B01D2325/20—Specific permeability or cut-off range
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/18—Apparatus therefor
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types

Landscapes

Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Electrochemistry (AREA)
Molecular Biology (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Water Supply & Treatment (AREA)
Medicinal Chemistry (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Inorganic Chemistry (AREA)
Biophysics (AREA)
Environmental & Geological Engineering (AREA)
Genetics & Genomics (AREA)
General Chemical & Material Sciences (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Physics & Mathematics (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Separation Using Semi-Permeable Membranes (AREA)
Urology & Nephrology (AREA)
Electrostatic Separation (AREA)
Peptides Or Proteins (AREA)

CN201710120140.6A 2012-03-21 2013-03-20 分子分离装置 Pending CN106823846A (zh)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US201261613578P	2012-03-21	2012-03-21
US61/613,578		2012-03-21
CN201380014845.XA CN104245094A (zh)	2012-03-21	2013-03-20	分子分离装置

Related Parent Applications (1)

Application Number	Title	Priority Date	Filing Date
CN201380014845.XA Division CN104245094A (zh)	2012-03-21	2013-03-20	分子分离装置

Publications (1)

Publication Number	Publication Date
CN106823846A true CN106823846A (zh)	2017-06-13

Family

ID=48050312

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
CN201710120140.6A Pending CN106823846A (zh)	2012-03-21	2013-03-20	分子分离装置
CN201380014845.XA Pending CN104245094A (zh)	2012-03-21	2013-03-20	分子分离装置

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
CN201380014845.XA Pending CN104245094A (zh)	2012-03-21	2013-03-20	分子分离装置

Country Status (12)

Country	Link
US (2)	US9028663B2 (2)
EP (1)	EP2827974A1 (2)
JP (2)	JP2015511531A (2)
KR (1)	KR20140147855A (2)
CN (2)	CN106823846A (2)
AU (2)	AU2013235234A1 (2)
CA (1)	CA2865648A1 (2)
IL (1)	IL234685A0 (2)
IN (1)	IN2014DN07731A (2)
SA (1)	SA113340401B1 (2)
SG (1)	SG11201405347PA (2)
WO (1)	WO2013142539A1 (2)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US9475709B2 (en)	2010-08-25	2016-10-25	Lockheed Martin Corporation	Perforated graphene deionization or desalination
US9193587B2 (en)	2011-07-13	2015-11-24	Lockheed Martin Corporation	System and method for water purification and desalination
SG11201405346RA (en)	2012-03-21	2014-10-30	Lockheed Corp	Methods for perforating graphene using an activated gas stream and perforated graphene produced therefrom
US9095823B2 (en) *	2012-03-29	2015-08-04	Lockheed Martin Corporation	Tunable layered membrane configuration for filtration and selective isolation and recovery devices
US9463421B2 (en)	2012-03-29	2016-10-11	Lockheed Martin Corporation	Planar filtration and selective isolation and recovery device
US10653824B2 (en)	2012-05-25	2020-05-19	Lockheed Martin Corporation	Two-dimensional materials and uses thereof
US9844757B2 (en)	2014-03-12	2017-12-19	Lockheed Martin Corporation	Separation membranes formed from perforated graphene and methods for use thereof
US20150258498A1 (en) *	2014-03-12	2015-09-17	Lockheed Martin Corporation	Graphene-based molecular separation and sequestration device and methods for harvest and recovery
US9610546B2 (en)	2014-03-12	2017-04-04	Lockheed Martin Corporation	Separation membranes formed from perforated graphene and methods for use thereof
US10376845B2 (en)	2016-04-14	2019-08-13	Lockheed Martin Corporation	Membranes with tunable selectivity
US9744617B2 (en)	2014-01-31	2017-08-29	Lockheed Martin Corporation	Methods for perforating multi-layer graphene through ion bombardment
US9067811B1 (en) *	2012-05-25	2015-06-30	Lockheed Martin Corporation	System, method, and control for graphenoid desalination
US9834809B2 (en)	2014-02-28	2017-12-05	Lockheed Martin Corporation	Syringe for obtaining nano-sized materials for selective assays and related methods of use
TW201504140A (zh)	2013-03-12	2015-02-01	Lockheed Corp	形成具有均勻孔尺寸之多孔石墨烯之方法
EP2969153A1 (en)	2013-03-13	2016-01-20	Lockheed Martin Corporation	Nanoporous membranes and methods for making the same
US9480952B2 (en)	2013-03-14	2016-11-01	Lockheed Martin Corporation	Methods for chemical reaction perforation of atomically thin materials
US9572918B2 (en)	2013-06-21	2017-02-21	Lockheed Martin Corporation	Graphene-based filter for isolating a substance from blood
CN105940479A (zh)	2014-01-31	2016-09-14	洛克希德马丁公司	使用宽离子场穿孔二维材料
CN106029596A (zh)	2014-01-31	2016-10-12	洛克希德马丁公司	采用多孔非牺牲性支撑层的二维材料形成复合结构的方法
AU2015229296A1 (en) *	2014-03-12	2016-10-27	Lockheed Martin Corporation	In vivo and in vitro use of graphene
JP2017534311A (ja) *	2014-09-02	2017-11-24	ロッキード・マーチン・コーポレーション	二次元膜材料をベースとする血液透析膜および血液濾過膜、ならびにそれを用いた方法
EP3253429A2 (en) *	2015-02-06	2017-12-13	Cabot Corporation	Urea sequestration compositions and methods
JP2018528144A (ja)	2015-08-05	2018-09-27	ロッキード・マーチン・コーポレーション	グラフェン系材料の穿孔可能なシート
WO2017023377A1 (en)	2015-08-06	2017-02-09	Lockheed Martin Corporation	Nanoparticle modification and perforation of graphene
EP3442697A4 (en)	2016-04-14	2020-03-18	Lockheed Martin Corporation	SELECTIVE INTERFACE REDUCTION OF GRAPH DEFECTS
WO2017180134A1 (en)	2016-04-14	2017-10-19	Lockheed Martin Corporation	Methods for in vivo and in vitro use of graphene and other two-dimensional materials
EP3442739A4 (en)	2016-04-14	2020-03-04	Lockheed Martin Corporation	PROCESS FOR PROCESSING GRAPHENE SHEETS FOR LARGE SCALE TRANSFER USING A FREE FLOATING PROCESS
KR20180133430A (ko)	2016-04-14	2018-12-14	록히드 마틴 코포레이션	결함 형성 또는 힐링의 인 시츄 모니터링 및 제어를 위한 방법
EP3442786A4 (en)	2016-04-14	2020-03-18	Lockheed Martin Corporation	TWO-DIMENSIONAL MEMBRANE STRUCTURES HAVING FLOW PASSAGES

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20100327847A1 (en) *	2007-09-12	2010-12-30	President And Fellows Of Harvard College	High-Resolution Molecular Sensor
WO2011046706A1 (en) *	2009-09-18	2011-04-21	President And Fellows Of Harvard College	Bare single-layer graphene membrane having a nanopore enabling high-sensitivity molecular detection and analysis
US20120048804A1 (en) *	2010-08-25	2012-03-01	Lockheed Martin Corporation	Perforated graphene deionization or desalination

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MA26028A1 (fr)	1997-01-09	2004-04-01	Garfield Int Invest Ltd	Dessalement de l'eau
GB0100513D0 (en)	2001-01-09	2001-02-21	Smithkline Beecham Plc	Process
JP3939943B2 (ja)	2001-08-29	2007-07-04	株式会社Ｇｓｉクレオス	気相成長法による炭素繊維からなるフィルター材
US7166443B2 (en)	2001-10-11	2007-01-23	Aviva Biosciences Corporation	Methods, compositions, and automated systems for separating rare cells from fluid samples
US7326326B2 (en) *	2002-09-11	2008-02-05	Temple University-Of The Commonwealth System Of Higher Education	System and methods for electrophoretic separation of proteins on protein binding membranes
US7150813B2 (en) *	2003-06-12	2006-12-19	Palo Alto Research Center Incorporated	Isoelectric focusing (IEF) of proteins with sequential and oppositely directed traveling waves in gel electrophoresis
US7410574B2 (en)	2004-03-03	2008-08-12	Patent Innovations Llc	Magnetic particle filtration apparatus
DE102004062535A1 (de)	2004-12-24	2006-07-06	Forschungszentrum Karlsruhe Gmbh	Semipermeables Membransystem für magnetische Partikelfraktionen
DE102005012594A1 (de) *	2005-03-18	2006-09-21	Bayer Technology Services Gmbh	Elektrofiltrationsverfahren
US20100059378A1 (en)	2007-07-18	2010-03-11	The Water Company Llc	Apparatus and method for removal of ions from a porous electrode that is part of a deionization system
US8409450B2 (en) *	2008-03-24	2013-04-02	The Regents Of The University Of California	Graphene-based structure, method of suspending graphene membrane, and method of depositing material onto graphene membrane
US8147599B2 (en)	2009-02-17	2012-04-03	Mcalister Technologies, Llc	Apparatuses and methods for storing and/or filtering a substance
EP2230511B1 (en)	2009-03-20	2017-04-26	Ecole Polytechnique	Method for varying the diameter of a nanopore contained in a nanoporous membrane functionalised with a ph-dependent polyelectrolyte
WO2011019686A1 (en)	2009-08-10	2011-02-17	Danisco Us Inc.	Cross-flow membrane filtration-based process for protein recovery
US8292092B2 (en) *	2009-09-08	2012-10-23	Teledyne Scientific & Imaging, Llc	Macrocyclic pore-apertured carbon nanotube apparatus
CN102781558B (zh)	2009-11-25	2015-06-24	悉尼大学	膜及膜分离系统
AU2011279530A1 (en)	2010-07-14	2013-01-31	Monash University	Material and applications therefor
JP2013535467A (ja) *	2010-07-28	2013-09-12	スマートセルズ・インコーポレイテツド	組換えにより発現されたインスリンポリペプチドおよびその使用
US9475709B2 (en) *	2010-08-25	2016-10-25	Lockheed Martin Corporation	Perforated graphene deionization or desalination
KR101211850B1 (ko)	2010-09-01	2012-12-12	연세대학교 산학협력단	그라핀 나노 필터 망, 그라핀 나노 필터 및 그 제조방법
WO2012030368A1 (en)	2010-09-01	2012-03-08	Lawrence Curtin	Application of radio frequency to fluidized beds
CN102242062B (zh) *	2011-04-19	2012-12-19	浙江大学	一种高分辨率的生物传感器
WO2013115762A1 (en) *	2012-01-27	2013-08-08	Empire Technology Development, Llc	Accelerating transport through graphene membranes
US11135546B2 (en) *	2012-03-15	2021-10-05	Massachusetts Institute Of Technology	Graphene based filter
SG11201405346RA (en) *	2012-03-21	2014-10-30	Lockheed Corp	Methods for perforating graphene using an activated gas stream and perforated graphene produced therefrom
US9610546B2 (en) *	2014-03-12	2017-04-04	Lockheed Martin Corporation	Separation membranes formed from perforated graphene and methods for use thereof
US9067811B1 (en) *	2012-05-25	2015-06-30	Lockheed Martin Corporation	System, method, and control for graphenoid desalination
TW201504140A (zh) *	2013-03-12	2015-02-01	Lockheed Corp	形成具有均勻孔尺寸之多孔石墨烯之方法
US9572918B2 (en) *	2013-06-21	2017-02-21	Lockheed Martin Corporation	Graphene-based filter for isolating a substance from blood
WO2015077751A1 (en) *	2013-11-25	2015-05-28	Northeastern University	Freestanding ultra thin membranes and transfer-free fabrication thereof

2013
- 2013-03-14 US US13/804,085 patent/US9028663B2/en not_active Expired - Fee Related
- 2013-03-20 SG SG11201405347PA patent/SG11201405347PA/en unknown
- 2013-03-20 CN CN201710120140.6A patent/CN106823846A/zh active Pending
- 2013-03-20 CA CA2865648A patent/CA2865648A1/en not_active Abandoned
- 2013-03-20 SA SA113340401A patent/SA113340401B1/ar unknown
- 2013-03-20 EP EP13714806.0A patent/EP2827974A1/en not_active Withdrawn
- 2013-03-20 AU AU2013235234A patent/AU2013235234A1/en not_active Abandoned
- 2013-03-20 IN IN7731DEN2014 patent/IN2014DN07731A/en unknown
- 2013-03-20 CN CN201380014845.XA patent/CN104245094A/zh active Pending
- 2013-03-20 KR KR1020147029539A patent/KR20140147855A/ko not_active Withdrawn
- 2013-03-20 JP JP2015501867A patent/JP2015511531A/ja active Pending
- 2013-03-20 WO PCT/US2013/033035 patent/WO2013142539A1/en not_active Ceased
2014
- 2014-09-16 IL IL234685A patent/IL234685A0/en unknown
2015
- 2015-04-14 US US14/686,452 patent/US20150218210A1/en not_active Abandoned
2017
- 2017-01-11 JP JP2017002652A patent/JP2017100127A/ja active Pending
2018
- 2018-01-05 AU AU2018200090A patent/AU2018200090A1/en not_active Abandoned

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20100327847A1 (en) *	2007-09-12	2010-12-30	President And Fellows Of Harvard College	High-Resolution Molecular Sensor
WO2011046706A1 (en) *	2009-09-18	2011-04-21	President And Fellows Of Harvard College	Bare single-layer graphene membrane having a nanopore enabling high-sensitivity molecular detection and analysis
US20120048804A1 (en) *	2010-08-25	2012-03-01	Lockheed Martin Corporation	Perforated graphene deionization or desalination

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EP2827974A1 (en)	2015-01-28
JP2015511531A (ja)	2015-04-20
AU2013235234A1 (en)	2014-10-16
IN2014DN07731A (2)	2015-05-15
US20150218210A1 (en)	2015-08-06
WO2013142539A1 (en)	2013-09-26
KR20140147855A (ko)	2014-12-30
US9028663B2 (en)	2015-05-12
AU2018200090A1 (en)	2018-01-25
US20130248367A1 (en)	2013-09-26
SA113340401B1 (ar)	2015-08-16
JP2017100127A (ja)	2017-06-08
CN104245094A (zh)	2014-12-24
SG11201405347PA (en)	2014-10-30
IL234685A0 (en)	2014-11-30
CA2865648A1 (en)	2013-09-26

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Publication	Publication Date	Title
CN106823846A (zh)	2017-06-13	分子分离装置
Qiu et al.	2013	Selective separation of similarly sized proteins with tunable nanoporous block copolymer membranes
US9089819B2 (en)	2015-07-28	Particulate nanosorting stack
US9833782B2 (en)	2017-12-05	Integrated nanofluidic arrays for high capacity colloid separation
CN103353476A (zh)	2013-10-16	分离并离析细胞、囊泡、纳米颗粒和生物标记的离体多维系统
US10118130B2 (en)	2018-11-06	Two-dimensional membrane structures having flow passages
WO2014150359A1 (en)	2014-09-25	Methods for chemical reaction perforation of atomically thin materials
CN1234116A (zh)	1999-11-03	用于活性生物样品制备的设备和方法
US10730042B2 (en)	2020-08-04	Biological detection system
CN104335044A (zh)	2015-02-04	用于分子分离、纯化和检测的装置和方法
US9956529B2 (en)	2018-05-01	Microfabricated ion-selective filter for filtration of ions and molecules
CN104379261A (zh)	2015-02-25	用于生物分子检测的纳米毛细管装置、流体网络结构和其制造方法
Chen et al.	2017	Assembly of ultrathin gold nanowires: from polymer analogue to colloidal block
US20200191767A1 (en)	2020-06-18	Controlling Translocating Molecules Through A Nanopore
WO2003011553A1 (en)	2003-02-13	On-chip membrane maker
JP6766944B2 (ja)	2020-10-14	ナノカーボンの分離方法
JP6237965B1 (ja)	2017-11-29	ナノカーボンの分離装置及び分離方法
Wu et al.	2012	Ionic rectification by electrostatically actuated tethers on single walled carbon nanotube membranes
KR101472486B1 (ko)	2014-12-12	폐슬러지 재생장치
KR20180073353A (ko)	2018-07-02	나노 필터를 이용한 핵산 추출 장치 및 방법
Fiedler et al.	1995	Electrocasting-formation and structuring of suspended microbodies using ac generated field cages
JP5239004B2 (ja)	2013-07-17	異方性ポリマー微粒子の製造法
Zhang	2022	Showcasing research from Prof. Mao-Sheng Zhang's group at Fujian Province University Key Laboratory of Analytical Science, Minnan Normal University, Zhangzhou, China. Green synthesis of highly stable CsPbBr 3 perovskite nanocrystals using natural deep eutectic solvents as
WO2025059762A1 (en)	2025-03-27	Method and device for electroseparation of charged particles
Dalir et al.	2016	Three-dimensional dielectrophoretic microparticle separator fabricated by ultraviolet-assisted direct-write assembly