CN106901352A - A kind of l threonic acid and its processing method - Google Patents
A kind of l threonic acid and its processing method Download PDFInfo
- Publication number
- CN106901352A CN106901352A CN201510972624.4A CN201510972624A CN106901352A CN 106901352 A CN106901352 A CN 106901352A CN 201510972624 A CN201510972624 A CN 201510972624A CN 106901352 A CN106901352 A CN 106901352A
- Authority
- CN
- China
- Prior art keywords
- threonic acid
- parts
- oxygen
- processing method
- calcium ascorbate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- JPIJQSOTBSSVTP-STHAYSLISA-N L-threonic acid Chemical compound OC[C@H](O)[C@@H](O)C(O)=O JPIJQSOTBSSVTP-STHAYSLISA-N 0.000 title claims abstract description 23
- 229940056902 l- threonic acid Drugs 0.000 title claims abstract description 23
- 238000003672 processing method Methods 0.000 title claims abstract description 12
- 235000010376 calcium ascorbate Nutrition 0.000 claims abstract description 18
- 229940047036 calcium ascorbate Drugs 0.000 claims abstract description 18
- 239000011692 calcium ascorbate Substances 0.000 claims abstract description 18
- BLORRZQTHNGFTI-ZZMNMWMASA-L calcium-L-ascorbate Chemical compound [Ca+2].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-] BLORRZQTHNGFTI-ZZMNMWMASA-L 0.000 claims abstract description 18
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims abstract description 17
- 239000001301 oxygen Substances 0.000 claims abstract description 17
- 229910052760 oxygen Inorganic materials 0.000 claims abstract description 17
- 102000004190 Enzymes Human genes 0.000 claims abstract description 12
- 108090000790 Enzymes Proteins 0.000 claims abstract description 12
- 239000002994 raw material Substances 0.000 claims abstract description 6
- 238000001914 filtration Methods 0.000 claims description 9
- 239000012065 filter cake Substances 0.000 claims description 6
- 239000007787 solid Substances 0.000 claims description 6
- 238000001035 drying Methods 0.000 claims description 5
- 238000002425 crystallisation Methods 0.000 claims description 3
- 230000008025 crystallization Effects 0.000 claims description 3
- 239000000706 filtrate Substances 0.000 claims description 3
- 239000007788 liquid Substances 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 claims 1
- 229910001882 dioxygen Inorganic materials 0.000 claims 1
- 239000000047 product Substances 0.000 abstract description 10
- 238000000034 method Methods 0.000 abstract description 7
- 208000001132 Osteoporosis Diseases 0.000 abstract description 5
- 238000004519 manufacturing process Methods 0.000 abstract description 5
- 239000013589 supplement Substances 0.000 abstract description 5
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract description 4
- 229910052791 calcium Inorganic materials 0.000 abstract description 4
- 239000011575 calcium Substances 0.000 abstract description 4
- 230000008569 process Effects 0.000 abstract description 3
- 208000024891 symptom Diseases 0.000 abstract description 3
- 235000013361 beverage Nutrition 0.000 description 1
- IMYZCYXTVFOXAQ-LJUKVTEVSA-N calcium;(2r,3s)-2,3,4-trihydroxybutanoic acid Chemical compound [Ca].OC[C@H](O)[C@@H](O)C(O)=O IMYZCYXTVFOXAQ-LJUKVTEVSA-N 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000012847 fine chemical Substances 0.000 description 1
- 235000013373 food additive Nutrition 0.000 description 1
- 239000002778 food additive Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000012567 medical material Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/58—Aldonic, ketoaldonic or saccharic acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
----the invention provides a kind of l threonic acid, is made up of following raw material：Calcium ascorbate, oxygen, calcium ascorbate and oxygen react in the presence of biology enzyme.The invention also discloses a kind of processing method of l threonic acid.The l threonic acid that technique of the invention is made, technological process is short, and course of reaction is easily controlled, and equipment is simple, without complicated subsequent treatment operation, solves the problems, such as that production process is numerous and diverse；Product quality is stable simultaneously, and product purity is high, is conducive to the calcareous supplement of the crowd of replenishing the calcium to absorb and treatment osteoporosis symptoms.
Description
【Technical field】
The present invention relates to l threonic acid processing technique field, more particularly, to a kind of l threonic acid and its processing method.
【Background technology】
Child growth needs to be continuously replenished calcareous, old man to overcome osteoporosis also to want supplement calcium and other nutriments.
L threonic acid is easily absorbed by the body, and is that a kind of supplement human body is calcareous, treats the good nutriment of osteoporosis, widely
Food additives, medical material, health products, beverage/food and fine chemical material are applied to, application field is extensive.Existing L-
Threonic acid calcium unstable product quality, product purity be not high, and the technological process of production is long, course of reaction is difficult to control, follow-up place
The shortcomings of managing cumbersome.
【The content of the invention】
In view of this, it is a primary object of the present invention to provide a kind of l threonic acid and its processing method, can solve the problem that existing
Complex manufacturing technology, the problem of unstable product quality.
To achieve the above object, the technical scheme taken of the present invention is：
On the one hand, the invention provides a kind of l threonic acid, it is prepared from the following raw materials in parts by weight：Calcium ascorbate 65-70
Part, oxygen 30-35 parts, the calcium ascorbate and the oxygen react under 0.03-0.05 parts of biological enzyme effect.
Preferably, a kind of l threonic acid, is prepared from the following raw materials in parts by weight：68 parts of calcium ascorbate, oxygen 32
Part, the calcium ascorbate and the oxygen react under 0.04 part of biological enzyme effect.
On the other hand, the invention provides a kind of l threonic acid and its processing method, its step includes：
（1）Calcium ascorbate, oxygen and biology enzyme are weighed in proportion；
（2）The calcium ascorbate adds water to add the oxygen and the biology enzyme after being dissolved, and reacts 2 hours；
（3）Reacted liquid is carried out to filter filter residue；
（4）Consider equipment using film by the filtrate for filtering to be dehydrated；
（5）It is put into crystallizing tank to be crystallized, forms crystalline solid；
（6）The crystalline solid is dehydrated through centrifuge, isolated filter cake；
（7）The filter cake is carried out into microwave drying.
Preferably, step（2）In reaction temperature control in 30-40 degree.
Preferably, step（3）The number of times of middle filtering is 3 times, and each filtration time is 1.5 hours.
Preferably, step（5）The time of middle crystallization is 16 hours.
Preferably, step（7）The temperature of middle microwave drying is 95-100 degrees Celsius.
Compared with prior art, the present invention has the advantages that：The l threonic acid that technique of the invention is made, work
Skill flow is short, and course of reaction is easily controlled, and equipment is simple, without complicated subsequent treatment operation, solves production process numerous and diverse
Problem；Product quality is stable simultaneously, and product purity is high, is conducive to the calcareous supplement of the crowd of replenishing the calcium to absorb and treatment osteoporosis
Symptom.
【Specific embodiment】
The present invention is described in further details below in conjunction with embodiment：
The invention provides a kind of l threonic acid, it is prepared from the following raw materials in parts by weight：Calcium ascorbate 65-70 parts, oxygen
30-35 parts, the calcium ascorbate and the oxygen react under 0.03-0.05 parts of biological enzyme effect.
A kind of processing method of l threonic acid, its step includes：
（1）68 parts of calcium ascorbate, 32 parts of oxygen, 0.04 part of biology enzyme are weighed in proportion；
（2）Calcium ascorbate adds water to add oxygen and biology enzyme after being dissolved, and reacts 2 hours；Wherein, reaction temperature control
In 30-40 degree；
（3）Reacted liquid is carried out to filter filter residue；Wherein, the number of times of filtering is 3 times, and each filtration time is 1.5 small
When；
（4）Consider equipment using film by the filtrate for filtering to be dehydrated；
（5）It is put into crystallizing tank to be crystallized, forms crystalline solid；Wherein, the time of crystallization is 16 hours；
（6）Crystalline solid is dehydrated through centrifuge, isolated filter cake；
（7）Filter cake is carried out into microwave drying；Wherein, the temperature of microwave drying is 95-100 degrees Celsius.
The l threonic acid that the technique of the above embodiment of the present invention is made, technological process is short, and course of reaction is easily controlled,
Equipment is simple, without complicated subsequent treatment operation, solves the problems, such as that production process is numerous and diverse；Product quality stabilization, produces simultaneously
Product purity is high, is conducive to the calcareous supplement of the crowd of replenishing the calcium to absorb and treatment osteoporosis symptoms.
The preferred embodiments of the present invention are the foregoing is only, is not intended to limit the invention, for the skill of this area
For art personnel, the present invention can have various modifications and variations.It is all within the spirit and principles in the present invention, made any repair
Change, equivalent, improvement etc., should be included within the scope of the present invention.
Claims (7)
1. a kind of l threonic acid, it is characterised in that be prepared from the following raw materials in parts by weight：Calcium ascorbate 65-70 parts, oxygen
Gas 30-35 parts, the calcium ascorbate and the oxygen react under 0.03-0.05 parts of biological enzyme effect.
2. a kind of l threonic acid according to claim 1, it is characterised in that be prepared from the following raw materials in parts by weight：
68 parts of calcium ascorbate, 32 parts of oxygen, the calcium ascorbate and the oxygen react under 0.04 part of biological enzyme effect.
3. a kind of processing method of l threonic acid, it is characterised in that comprise the following steps：
（1）Calcium ascorbate, oxygen and biology enzyme are weighed in proportion；
（2）The calcium ascorbate adds water to add the oxygen and the biology enzyme after being dissolved, and reacts 2 hours；
（3）Reacted liquid is carried out to filter filter residue；
（4）Consider equipment using film by the filtrate for filtering to be dehydrated；
（5）It is put into crystallizing tank to be crystallized, forms crystalline solid；
（6）The crystalline solid is dehydrated through centrifuge, isolated filter cake；
（7）The filter cake is carried out into microwave drying.
4. a kind of processing method of l threonic acid according to claim 3, it is characterised in that step（2）In reaction
Temperature control is in 30-40 degree.
5. a kind of processing method of l threonic acid according to claim 3, it is characterised in that step（3）Middle filtering
Number of times is 3 times, and each filtration time is 1.5 hours.
6. a kind of processing method of l threonic acid according to claim 3, it is characterised in that step（5）Middle crystallization
Time is 16 hours.
7. a kind of processing method of l threonic acid according to claim 3, it is characterised in that step（7）Middle microwave is done
Dry temperature is 95-100 degrees Celsius.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510972624.4A CN106901352A (en) | 2015-12-23 | 2015-12-23 | A kind of l threonic acid and its processing method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510972624.4A CN106901352A (en) | 2015-12-23 | 2015-12-23 | A kind of l threonic acid and its processing method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106901352A true CN106901352A (en) | 2017-06-30 |
Family
ID=59200024
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510972624.4A Pending CN106901352A (en) | 2015-12-23 | 2015-12-23 | A kind of l threonic acid and its processing method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106901352A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112047836A (en) * | 2020-09-16 | 2020-12-08 | 浙江天瑞化学有限公司 | Preparation method and equipment of calcium L-threonate |
-
2015
- 2015-12-23 CN CN201510972624.4A patent/CN106901352A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112047836A (en) * | 2020-09-16 | 2020-12-08 | 浙江天瑞化学有限公司 | Preparation method and equipment of calcium L-threonate |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20170630 |
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| WD01 | Invention patent application deemed withdrawn after publication |