CN1073264A - 基于组织的特定的nt-3表达与受体结合的治疗和诊断方法 - Google Patents

基于组织的特定的nt-3表达与受体结合的治疗和诊断方法 Download PDF

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Publication number
CN1073264A
CN1073264A CN92114650A CN92114650A CN1073264A CN 1073264 A CN1073264 A CN 1073264A CN 92114650 A CN92114650 A CN 92114650A CN 92114650 A CN92114650 A CN 92114650A CN 1073264 A CN1073264 A CN 1073264A
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CN
China
Prior art keywords
cell
neuron
brain
ngf
tissue
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Pending
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CN92114650A
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English (en)
Chinese (zh)
Inventor
C·A·阿尔塔
P·迪斯蒂芬诺
S·韦冈
N·叶
C·希曼
R·文蒂米格利亚
R·林赛
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Regeneron Pharmaceuticals Inc
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Regeneron Pharmaceuticals Inc
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Publication date
Application filed by Regeneron Pharmaceuticals Inc filed Critical Regeneron Pharmaceuticals Inc
Publication of CN1073264A publication Critical patent/CN1073264A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Psychology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN92114650A 1991-11-12 1992-11-12 基于组织的特定的nt-3表达与受体结合的治疗和诊断方法 Pending CN1073264A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79085791A 1991-11-12 1991-11-12
US790,857 1991-11-12

Publications (1)

Publication Number Publication Date
CN1073264A true CN1073264A (zh) 1993-06-16

Family

ID=25151941

Family Applications (1)

Application Number Title Priority Date Filing Date
CN92114650A Pending CN1073264A (zh) 1991-11-12 1992-11-12 基于组织的特定的nt-3表达与受体结合的治疗和诊断方法

Country Status (6)

Country Link
CN (1) CN1073264A (pt)
AU (1) AU3130493A (pt)
IL (1) IL103730A0 (pt)
PT (1) PT101051A (pt)
WO (1) WO1993009798A1 (pt)
ZA (1) ZA928730B (pt)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110812532A (zh) * 2019-08-20 2020-02-21 中山大学 一种靶向促进皮质脊髓束连接以修复脊髓损伤的组织工程支架的构建方法

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU733394B2 (en) * 1996-10-16 2001-05-10 Regeneron Pharmaceuticals, Inc. Method of enhancing the delivery of growth factors
WO1998021245A1 (de) * 1996-11-08 1998-05-22 Roche Diagnostics Gmbh eOCHAFFINE ANTIKÖRPER GEGEN HUMAN-BDNF, VERFAHREN ZU IHRER HERSTELLUNG UND VERWENDUNG
EP1050758A1 (en) * 1999-05-03 2000-11-08 Evotec BioSystems AG Methods of diagnosing or treating neuropsychiatric diseases on basis of increased cerebrospinal fluid levels of neurotrophin 3
EP1173768B1 (en) * 1999-05-03 2006-10-25 Evotec AG Methods of diagnosing, prognosing, monitoring the progression or evaluating of a treatment of depression on basis of increased cerebrospinal fluid levels of neurotrophin 3
US6548062B2 (en) 2000-02-29 2003-04-15 Cephalon, Inc. Method of treating cancer with anti-neurotrophin agents

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4868107A (en) * 1986-11-18 1989-09-19 The United States Of America As Represented By The Department Of Health And Human Services Method for detecting antibodies against neuropeptides and drugs in human body fluid

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110812532A (zh) * 2019-08-20 2020-02-21 中山大学 一种靶向促进皮质脊髓束连接以修复脊髓损伤的组织工程支架的构建方法

Also Published As

Publication number Publication date
IL103730A0 (en) 1993-04-04
PT101051A (pt) 1994-02-28
AU3130493A (en) 1993-06-15
ZA928730B (en) 1993-05-10
WO1993009798A1 (en) 1993-05-27

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WD01 Invention patent application deemed withdrawn after publication