CN108135919B - 用于维持乳杆菌属优势的组合物 - Google Patents

用于维持乳杆菌属优势的组合物 Download PDF

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Publication number
CN108135919B
CN108135919B CN201580083308.XA CN201580083308A CN108135919B CN 108135919 B CN108135919 B CN 108135919B CN 201580083308 A CN201580083308 A CN 201580083308A CN 108135919 B CN108135919 B CN 108135919B
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China
Prior art keywords
composition
acid
growth
therapeutic agent
lactobacillus
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CN201580083308.XA
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English (en)
Chinese (zh)
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CN108135919A (zh
Inventor
J·李
L·A·皮德
C·F·乔伊纳
R·A·冯萨
D·W·凯尼格
R·D·巴特尔
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Kimberly Clark Worldwide Inc
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Kimberly Clark Worldwide Inc
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/191—Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016—Disaccharides, e.g. lactose, lactulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/719—Pullulans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201580083308.XA 2015-09-29 2015-09-29 用于维持乳杆菌属优势的组合物 Active CN108135919B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2015/052951 WO2017058174A1 (fr) 2015-09-29 2015-09-29 Composition pour le maintien de la dominance de lactobacillus

Publications (2)

Publication Number Publication Date
CN108135919A CN108135919A (zh) 2018-06-08
CN108135919B true CN108135919B (zh) 2024-06-18

Family

ID=58424235

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201580083308.XA Active CN108135919B (zh) 2015-09-29 2015-09-29 用于维持乳杆菌属优势的组合物

Country Status (8)

Country Link
US (2) US20180256615A1 (fr)
EP (2) EP3831391A1 (fr)
KR (2) KR20230165382A (fr)
CN (1) CN108135919B (fr)
AU (1) AU2015410634B2 (fr)
MX (1) MX390741B (fr)
RU (1) RU2723015C2 (fr)
WO (1) WO2017058174A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108235682A (zh) 2015-09-29 2018-06-29 金伯利-克拉克环球有限公司 用于维护微生物群落的健康平衡的协同组合物
KR102769558B1 (ko) 2017-02-28 2025-02-19 킴벌리-클라크 월드와이드, 인크. 미생물총의 건강한 균형을 유지하기 위한 상승적 조성물
KR102116686B1 (ko) 2020-01-02 2020-05-29 주식회사 쎌바이오텍 성장 인자를 포함하는 유산균 증식 촉진용 조성물
US20230293560A1 (en) * 2020-07-23 2023-09-21 Kimberly-Clark Worldwide, Inc. Method for modulating the bladder microbiome to improve bladder health
JP2023084325A (ja) * 2021-12-07 2023-06-19 株式会社希松 デーデルライン桿菌の増殖促進剤および微生物選択的増殖促進剤
US20260000694A1 (en) * 2022-07-29 2026-01-01 Kimberly-Clark Worldwide, Inc. Methods and compositions related to prebiotic formulations useful in promoting urogenital health

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101411714A (zh) * 2007-10-15 2009-04-22 杜军 治疗阴道炎的化学物质
WO2015135470A1 (fr) * 2014-03-13 2015-09-17 曾忠铭 Composition vaginale et son utilisation

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US4326053A (en) 1978-12-04 1982-04-20 Merck & Co., Inc. Polysaccharide S-60 and bacterial fermentation process for its preparation
KR830002802B1 (ko) 1978-12-04 1983-12-16 제임스 에프 · 너우톤 박테리아 발효에 의한 다당류 s-60의 제조방법
US4385123A (en) 1979-06-08 1983-05-24 Merck & Co., Inc. Deacetylated polysaccharide S-60
US4377636A (en) 1979-06-08 1983-03-22 Merck & Co., Inc. Polysaccharide S-60 and bacterial fermentation process for its preparation
US4563366A (en) 1983-05-31 1986-01-07 Merck & Co., Inc. Non-heated gellan gum gels
AU1854297A (en) * 1996-02-14 1997-09-02 Procter & Gamble Company, The Urogenital and intestinal disorder compositions comprising substance derived from plant species of the ericaceae family and a lactic acid bacteria growth factor
US6964949B2 (en) * 2000-05-24 2005-11-15 Shanghai Jiao Da Onlly Co., Ltd. Pharmaceutical compositions for promoting the growth of gram-positive bacilli and increasing the acidity in the vagina and the use thereof
CN1562049A (zh) 2004-04-02 2005-01-12 聂四平 低聚果糖在制备治疗及预防阴道炎药中的应用
FR2874825B1 (fr) * 2004-09-08 2006-12-08 Genibio Sarl Utilisations d'oligosaccharides prebiotiques benefiques pour la flore vaginale
US7619008B2 (en) * 2004-11-12 2009-11-17 Kimberly-Clark Worldwide, Inc. Xylitol for treatment of vaginal infections
CN101175503B (zh) * 2005-04-27 2012-12-12 深圳福诺生物技术有限公司 一种调节并保持阴道菌群和阴道酸度正常的组合物与方法
CN101304751A (zh) * 2005-10-13 2008-11-12 明治制果株式会社 肠内菌群改善用组合物
FI122247B (fi) * 2009-08-12 2011-10-31 Vetcare Oy Probioottinen valmiste koiran maha- ja suolistokanavassa ilmenevien häiriöiden ennaltaehkäisemiseksi tai hoitamiseksi
RU2473347C1 (ru) * 2011-11-09 2013-01-27 Сергей Константинович Панюшин Композиция пребиотиков для нормализации микрофлоры организма
CN102870987B (zh) * 2012-09-19 2013-12-11 广州立达尔生物科技股份有限公司 一种用于改善幼龄动物肠道发育的绿色饲料添加剂

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101411714A (zh) * 2007-10-15 2009-04-22 杜军 治疗阴道炎的化学物质
WO2015135470A1 (fr) * 2014-03-13 2015-09-17 曾忠铭 Composition vaginale et son utilisation

Also Published As

Publication number Publication date
US20180256615A1 (en) 2018-09-13
MX390741B (es) 2025-03-21
AU2015410634B2 (en) 2021-09-30
EP3355894B1 (fr) 2024-04-24
WO2017058174A1 (fr) 2017-04-06
EP3355894A4 (fr) 2019-05-29
RU2723015C2 (ru) 2020-06-08
US20220257622A1 (en) 2022-08-18
KR20180054653A (ko) 2018-05-24
KR20230165382A (ko) 2023-12-05
EP3831391A1 (fr) 2021-06-09
MX2018002997A (es) 2018-05-07
AU2015410634A1 (en) 2018-04-12
RU2018111436A (ru) 2019-10-01
RU2018111436A3 (fr) 2019-10-01
EP3355894A1 (fr) 2018-08-08
CN108135919A (zh) 2018-06-08

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