CN1090477C - 含布洛芬的固体组合物 - Google Patents

含布洛芬的固体组合物 Download PDF

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Publication number
CN1090477C
CN1090477C CN94112789A CN94112789A CN1090477C CN 1090477 C CN1090477 C CN 1090477C CN 94112789 A CN94112789 A CN 94112789A CN 94112789 A CN94112789 A CN 94112789A CN 1090477 C CN1090477 C CN 1090477C
Authority
CN
China
Prior art keywords
ibuprofen
granules
water
coated
solid composite
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN94112789A
Other languages
English (en)
Chinese (zh)
Other versions
CN1109745A (zh
Inventor
神户英芳
中嶋洋
岩佐曜
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SSP Co Ltd
Original Assignee
SSP Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SSP Co Ltd filed Critical SSP Co Ltd
Publication of CN1109745A publication Critical patent/CN1109745A/zh
Application granted granted Critical
Publication of CN1090477C publication Critical patent/CN1090477C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/282—Organic compounds, e.g. fats
    • A61K9/2826—Sugars or sugar alcohols, e.g. sucrose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CN94112789A 1993-12-17 1994-12-17 含布洛芬的固体组合物 Expired - Fee Related CN1090477C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP5318530A JP2841267B2 (ja) 1993-12-17 1993-12-17 イブプロフェン含有粒剤
JP318530/93 1993-12-17

Publications (2)

Publication Number Publication Date
CN1109745A CN1109745A (zh) 1995-10-11
CN1090477C true CN1090477C (zh) 2002-09-11

Family

ID=18100149

Family Applications (1)

Application Number Title Priority Date Filing Date
CN94112789A Expired - Fee Related CN1090477C (zh) 1993-12-17 1994-12-17 含布洛芬的固体组合物

Country Status (4)

Country Link
JP (1) JP2841267B2 (2)
KR (1) KR100253525B1 (2)
CN (1) CN1090477C (2)
TW (1) TW276994B (2)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2315088A1 (en) * 1997-12-19 1999-07-01 Smithkline Beecham Corporation Process for manufacturing bite-dispersion tablets
JP2005035995A (ja) * 2003-07-01 2005-02-10 Sankyo Co Ltd イブプロフェン含有経口用組成物
JP4913359B2 (ja) * 2004-05-07 2012-04-11 第一三共ヘルスケア株式会社 イブプロフェン含有医薬組成物
JP2012046540A (ja) * 2004-05-07 2012-03-08 Daiichi Sankyo Healthcare Co Ltd イブプロフェン含有医薬組成物
JP4832045B2 (ja) * 2005-09-28 2011-12-07 ロート製薬株式会社 メキタジン、イブプロフェン及びトラネキサム酸含有医薬組成物
JP5465824B2 (ja) * 2006-03-24 2014-04-09 第一三共ヘルスケア株式会社 医薬用製剤およびその製造方法
JP5527921B2 (ja) * 2006-12-22 2014-06-25 エスエス製薬株式会社 苦味を隠蔽した経口固形組成物
BR112012012999A2 (pt) * 2009-11-30 2019-04-02 Aptalis Pharmatech, Inc. Composição farmacêutica, e composição de tablete de desintegração oral (odt) outablete de dispersão rápida (rdt)
WO2013183062A2 (en) * 2012-06-05 2013-12-12 Rubicon Research Private Limited Palatable formulations of ibuprofen
WO2014203819A1 (ja) * 2013-06-17 2014-12-24 日本曹達株式会社 ヒドロキシアルキルセルロースを含有するコーティング剤
FR3089756B1 (fr) * 2018-12-17 2021-02-19 Roquette Freres Formes solides dragéifiées présentant une stabilité améliorée

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0297866A2 (en) * 1987-07-01 1989-01-04 The Boots Company PLC Therapeutic agents

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0297866A2 (en) * 1987-07-01 1989-01-04 The Boots Company PLC Therapeutic agents

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
药剂学 1980.1.1 沈阳药学院，人民卫生出版社 *

Also Published As

Publication number Publication date
CN1109745A (zh) 1995-10-11
KR950016718A (ko) 1995-07-20
JP2841267B2 (ja) 1998-12-24
JPH07173057A (ja) 1995-07-11
KR100253525B1 (ko) 2000-05-01
TW276994B (2) 1996-06-01

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C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C19 Lapse of patent right due to non-payment of the annual fee
CF01 Termination of patent right due to non-payment of annual fee