CN109600902A - Low-temperature plasma activation liquid excitation apparatus and its application method - Google Patents
Low-temperature plasma activation liquid excitation apparatus and its application method Download PDFInfo
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- CN109600902A CN109600902A CN201811504238.2A CN201811504238A CN109600902A CN 109600902 A CN109600902 A CN 109600902A CN 201811504238 A CN201811504238 A CN 201811504238A CN 109600902 A CN109600902 A CN 109600902A
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- low
- deionized water
- temperature plasma
- aseptic deionized
- insulating cylinder
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- 238000000678 plasma activation Methods 0.000 title claims abstract description 26
- 230000005284 excitation Effects 0.000 title claims abstract description 21
- 239000007788 liquid Substances 0.000 title claims abstract description 13
- 238000000034 method Methods 0.000 title claims abstract description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 43
- 239000008367 deionised water Substances 0.000 claims abstract description 24
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 24
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims abstract description 17
- 229910052802 copper Inorganic materials 0.000 claims abstract description 17
- 239000010949 copper Substances 0.000 claims abstract description 17
- 208000035143 Bacterial infection Diseases 0.000 claims description 3
- 208000022362 bacterial infectious disease Diseases 0.000 claims description 3
- 230000000694 effects Effects 0.000 claims description 3
- 238000000338 in vitro Methods 0.000 claims description 3
- 241001661355 Synapsis Species 0.000 claims description 2
- 238000004659 sterilization and disinfection Methods 0.000 claims description 2
- 238000002242 deionisation method Methods 0.000 claims 1
- 230000001954 sterilising effect Effects 0.000 claims 1
- 241000894006 Bacteria Species 0.000 abstract description 16
- 208000015181 infectious disease Diseases 0.000 abstract description 8
- 230000001186 cumulative effect Effects 0.000 abstract description 3
- 230000003115 biocidal effect Effects 0.000 description 5
- 206010059866 Drug resistance Diseases 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 230000002779 inactivation Effects 0.000 description 3
- 244000005700 microbiome Species 0.000 description 3
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 2
- WKDDRNSBRWANNC-UHFFFAOYSA-N Thienamycin Natural products C1C(SCCN)=C(C(O)=O)N2C(=O)C(C(O)C)C21 WKDDRNSBRWANNC-UHFFFAOYSA-N 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- ZSKVGTPCRGIANV-ZXFLCMHBSA-N imipenem Chemical compound C1C(SCC\N=C\N)=C(C(O)=O)N2C(=O)[C@H]([C@H](O)C)[C@H]21 ZSKVGTPCRGIANV-ZXFLCMHBSA-N 0.000 description 2
- 229960002182 imipenem Drugs 0.000 description 2
- 230000002147 killing effect Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- DMJNNHOOLUXYBV-PQTSNVLCSA-N meropenem Chemical compound C=1([C@H](C)[C@@H]2[C@H](C(N2C=1C(O)=O)=O)[C@H](O)C)S[C@@H]1CN[C@H](C(=O)N(C)C)C1 DMJNNHOOLUXYBV-PQTSNVLCSA-N 0.000 description 2
- 229960002260 meropenem Drugs 0.000 description 2
- 230000000813 microbial effect Effects 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 229930186147 Cephalosporin Natural products 0.000 description 1
- RJQXTJLFIWVMTO-TYNCELHUSA-N Methicillin Chemical compound COC1=CC=CC(OC)=C1C(=O)N[C@@H]1C(=O)N2[C@@H](C(O)=O)C(C)(C)S[C@@H]21 RJQXTJLFIWVMTO-TYNCELHUSA-N 0.000 description 1
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 208000002847 Surgical Wound Diseases 0.000 description 1
- 206010053615 Thermal burn Diseases 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 229940124587 cephalosporin Drugs 0.000 description 1
- 150000001780 cephalosporins Chemical class 0.000 description 1
- NWFNSTOSIVLCJA-UHFFFAOYSA-L copper;diacetate;hydrate Chemical compound O.[Cu+2].CC([O-])=O.CC([O-])=O NWFNSTOSIVLCJA-UHFFFAOYSA-L 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 230000005283 ground state Effects 0.000 description 1
- 208000013210 hematogenous Diseases 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 229960003085 meticillin Drugs 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 238000009281 ultraviolet germicidal irradiation Methods 0.000 description 1
Classifications
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
- H05H1/00—Generating plasma; Handling plasma
- H05H1/24—Generating plasma
- H05H1/46—Generating plasma using applied electromagnetic fields, e.g. high frequency or microwave energy
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
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- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Plasma & Fusion (AREA)
- Inorganic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Electromagnetism (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Water Treatment By Electricity Or Magnetism (AREA)
Abstract
Low-temperature plasma activation liquid excitation apparatus and its application method, solves present drug-fast bacteria cumulative year after year, lead to the problem that clinically bacterium infection is difficult to treat comprising excitation body and high voltage power supply, excitation body upper end are connected through high-voltage conducting wires with the anode of high voltage power supply；The excitation body includes insulating cylinder, and multiple copper rods, parallel connection between multiple copper rods are fixed in insulating cylinder, aseptic deionized water device is equipped in insulating cylinder, the lower end of copper rod is placed in aseptic deionized water, and live wire is inserted into aseptic deionized water, and electric wire is connected through insulating cylinder with the cathode of high voltage power supply.
Description
Technical field
The present invention relates to lower temperature plasma technology fields, excite and fill more particularly, to a kind of low-temperature plasma activation liquid
It sets and its application method.
Background technique
Plasma is an emerging research field of rising in recent years, and plasma is famous by Britain first in 1879
Physicist and chemist William Crookes had found, the atmos low-temperature that then gradually appears, even room temperature etc. from
Daughter jet stream all greatly facilitates the research of people's plasma medical application.Plasma is gas by high-energy
Ionization generates when effect, mainly (such as monatomic by electronics, negative ions, ground state atom, excited atom, living radical
Oxygen, ozone, hydrogen peroxide etc.), UV irradiation etc. composition.These ingredients have very strong physical and chemical activity, may make cell bone
The macromolecular substances such as the microstructure of frame or protein, inhereditary material (DNA, RNA etc.) structure or property, microbial body in
Cytosome etc. change, and then promote its inhereditary material character and change perhaps to make microbial inactivation or by changing
Become the relevant enzymatic activity of microorganism, the metabolism for promoting its tissue changes, to have killing effect to microorganism.
Bialasiewica has studied low temperature plasma in nineteen ninety-five and handles the mould of crop surface, finds it to mould
There is good killing effect.It can be utilized to the processing etc. that carries out disinfection to water.
In recent years, due to antibody-resistant bacterium, such as the staphylococcus aureus of methicillin-resistant, the verdigris of resistance to cephalosporin are false
The emergence of monad etc., skin trauma infection, such as widespread skin is rotten to the corn after burn and scald, festers or sense that defect is incurred
Dye and the infection of post-surgical incisions etc., become more to be difficult to quickly heal, serious person can produce Hematogenous infection, jeopardize life
Life.It is clinically directed to such infection, typically using a large amount of antibiotic, such as Imipenem and Meropenem, but these
The emergence for leading to antibody-resistant bacterium using one side of antibiotic forces people constantly to research and develop new antibiotic to pursue constantly
On the other hand the infection of the microorganisms such as drug resistant bacterium has also been constantly increasing the financial burden of patient and society.It has reported at present
Road pseudomonas aeruginosa is higher and higher to the resistant rate of Imipenem and Meropenem, and general drug-fast bacteria recall rate is also in cumulative year after year
Gesture be unfavorable for the existence and health of the mankind for a long time.
Summary of the invention
For above situation, to overcome the shortcomings of existing technologies, it is sharp that the present invention provides a kind of low-temperature plasma activation liquid
Transmitting apparatus and its application method, the present drug-fast bacteria cumulative year after year of effective solution are unfavorable for the existence of the mankind and asking for health
Topic.
To achieve the above object, the present invention includes excitation body and high voltage power supply, excites body upper end through high-voltage conducting wires and high pressure
The anode of power supply is connected；
The excitation body includes insulating cylinder, is fixed with multiple copper rods in insulating cylinder, in parallel between multiple copper rods, in insulating cylinder
Equipped with aseptic deionized water device, the lower end of copper rod is placed in aseptic deionized water, and live wire is inserted into aseptic deionized water, electricity
Line is connected through insulating cylinder with the cathode of high voltage power supply.
Preferably, the high-voltage conducting wires are equipped with resistance.
A kind of application method of low-temperature plasma activation liquid excitation apparatus, it is characterised in that include the following steps:
D) a kind of low-temperature plasma activation liquid excitation apparatus of any of claims 1 or 2 is prepared；
E) ground wire is inserted into aseptic deionized water, connects high voltage power supply, is contacted in aseptic deionized water end face with copper rod
Place, ionization generate plasma light beam, wait in vitro light beam to irradiate aseptic deionized water 10-20 minutes, aseptic deionized water becomes
Low-temperature plasma activation water.
F) low-temperature plasma activation water is taken out, plasma-activated water is played applied to bacterial infection organism surface
Bactericidal effect.
The present apparatus production get up it is more convenient, cost is also cheaper, low-temperature plasma activation water production quickly, facing
When certain diseases are treated by Chuan Ge department, constantly expanded using the range of antibiotic, bacteriogenic drug resistance also increases therewith, together
When drug resistance range it is more and more wider, and in the state risen, higher and higher so as to cause medical expense, therapeutic effect is worse and worse very
To failure, drug-fast bacteria is placed in low-temperature plasma activation water by the low-temperature plasma activation water made by the present apparatus,
Death will occur in a very short period of time for bacterium.Using low-temperature plasma activation water as a kind of novel bacteria inactivation object
Matter, this provides reference to the treatment of shallow bacterium infection (including drug-fast bacteria) on future clinical, it will has great application
Prospect
Detailed description of the invention
Attached drawing is used to provide further understanding of the present invention, and constitutes part of specification, with reality of the invention
It applies example to be used to explain the present invention together, not be construed as limiting the invention.In the accompanying drawings:
Fig. 1 is schematic structural view of the invention.
Fig. 2 is present invention excitation body structural schematic diagram.
Specific embodiment
1-2 is described in further details a specific embodiment of the invention with reference to the accompanying drawing.
It is provided by Fig. 1-2, the present invention includes excitation body 1 and high voltage power supply 2, and high voltage power supply 2 uses D.C. regulated power supply, is swashed
Hair 1 upper end of body is connected through high-voltage conducting wires with the anode of high voltage power supply 2；
The excitation body 1 includes insulating cylinder 3, insulating cylinder 3 be it is hollow cylindric, multiple copper rods are fixed in insulating cylinder 3
4, in parallel between multiple copper rods 4,3 upper end of insulating cylinder is equipped with fixed disk, and multiple copper rods 4 are in parallel to be fixed in fixed plate, insulate
Aseptic deionized water is equipped in cylinder 3, the lower end of copper rod 4 is placed in aseptic deionized water, and copper rod 4 is inserted in aseptic deionized water
It is interior, live wire is inserted into aseptic deionized water, electric wire is connected through insulating cylinder 3 with the cathode of high voltage power supply 2, forms one in this way
Complete circuit, a circuit loop can be formed by opening high voltage power supply 2.
The high-voltage conducting wires are equipped with resistance 5, and it is appropriate that the resistance value of resistance 5 is chosen, and can be very good limitation electric discharge.
A kind of application method of low-temperature plasma activation liquid excitation apparatus, it is characterised in that include the following steps:
A) a kind of low-temperature plasma activation liquid excitation apparatus of any of claims 1 or 2 is prepared；
B) ground wire is inserted into aseptic deionized water, connects high voltage power supply 2, is connect in aseptic deionized water end face and copper rod 4
Synapsis, ionization generate plasma light beam, and in vitro light beam is waited to irradiate aseptic deionized water 10-20 minutes, aseptic deionized water at
For low-temperature plasma activation water.
C) low-temperature plasma activation water is taken out, plasma-activated water is played applied to bacterial infection organism surface
Bactericidal effect.
The present apparatus production get up it is more convenient, cost is also cheaper, low-temperature plasma activation water production quickly, facing
When certain diseases are treated by Chuan Ge department, constantly expanded using the range of antibiotic, bacteriogenic drug resistance also increases therewith, together
When drug resistance range it is more and more wider, and in the state risen, higher and higher so as to cause medical expense, therapeutic effect is worse and worse very
To failure, drug-fast bacteria is placed in low-temperature plasma activation water by the low-temperature plasma activation water made by the present apparatus,
Death will occur in a very short period of time for bacterium.Using low-temperature plasma activation water as a kind of novel bacteria inactivation object
Matter, this provides reference to the treatment of superficial bacterium infection on future clinical, it will has great application prospect.
Finally, it should be noted that the foregoing is only a preferred embodiment of the present invention, it is not intended to restrict the invention,
Although the present invention is described in detail referring to the foregoing embodiments, for those skilled in the art, still may be used
To modify the technical solutions described in the foregoing embodiments or equivalent replacement of some of the technical features.
All within the spirits and principles of the present invention, any modification, equivalent replacement, improvement and so on should be included in of the invention
Within protection scope.
Claims (3)
1. low-temperature plasma activation liquid excitation apparatus, which is characterized in that described to swash including excitation body (1) and high voltage power supply (2)
Hair body (1) upper end is connected through high-voltage conducting wires with the anode of high voltage power supply (2)；
The excitation body (1) includes insulating cylinder (3), is fixed with multiple copper rods (4) in insulating cylinder (3), between multiple copper rods (4) simultaneously
Connection, insulating cylinder (3) is interior to be equipped with aseptic deionized water device, and the lower end of copper rod (4) is placed in aseptic deionized water, sterile deionization
Live wire is inserted into water, electric wire is connected through insulating cylinder (3) with the cathode of high voltage power supply (2).
2. low-temperature plasma activation liquid excitation apparatus according to claim 1, which is characterized in that set on the high-voltage conducting wires
There are resistance (5).
3. a kind of application method of low-temperature plasma activation liquid excitation apparatus, it is characterised in that include the following steps:
A) low-temperature plasma activation liquid excitation apparatus of any of claims 1 or 2 is prepared；
B) ground wire is inserted into aseptic deionized water, connects high voltage power supply (2), is connect in aseptic deionized water end face and copper rod (4)
Synapsis, ionization generate plasma, and in vitro light beam is waited to irradiate aseptic deionized water 10-20 minutes, and aseptic deionized water becomes low
Isothermal plasma activated water.
C) low-temperature plasma activation water is taken out, plasma-activated water is applied to bacterial infection organism surface and plays sterilization
Effect.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811504238.2A CN109600902A (en) | 2018-12-10 | 2018-12-10 | Low-temperature plasma activation liquid excitation apparatus and its application method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811504238.2A CN109600902A (en) | 2018-12-10 | 2018-12-10 | Low-temperature plasma activation liquid excitation apparatus and its application method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109600902A true CN109600902A (en) | 2019-04-09 |
Family
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|---|---|---|---|
| CN201811504238.2A Pending CN109600902A (en) | 2018-12-10 | 2018-12-10 | Low-temperature plasma activation liquid excitation apparatus and its application method |
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|---|---|---|---|---|
| CN101112132A (en) * | 2004-12-03 | 2008-01-23 | 株式会社丰田自动织机 | Liquid plasma electrode, liquid plasma generating apparatus, and liquid plasma generating method |
| CN201499364U (en) * | 2009-09-09 | 2010-06-02 | 上海恺立贸易有限公司 | Novel plasma generating device |
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2018
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Application publication date: 20190409 |