CN110585111A - Anti-aging cosmetic additive and preparation method thereof - Google Patents
Anti-aging cosmetic additive and preparation method thereof Download PDFInfo
- Publication number
- CN110585111A CN110585111A CN201910983398.8A CN201910983398A CN110585111A CN 110585111 A CN110585111 A CN 110585111A CN 201910983398 A CN201910983398 A CN 201910983398A CN 110585111 A CN110585111 A CN 110585111A
- Authority
- CN
- China
- Prior art keywords
- parts
- sheep
- placenta
- tripeptide
- cosmetic additive
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
- A61K8/982—Reproductive organs; Embryos, Eggs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/82—Preparation or application process involves sonication or ultrasonication
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Developmental Biology & Embryology (AREA)
- Reproductive Health (AREA)
- Zoology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Cosmetics (AREA)
Abstract
The invention relates to an anti-aging cosmetic additive and a preparation method thereof, belonging to the technical field of anti-aging cosmetics, and the additive comprises the following components: 1-4 parts of hydrolyzed placenta (sheep) extract, 10.5-5 parts of palmitoyl tripeptide, 43-6 parts of palmitoyl pentapeptide, 1-3 parts of carnosine, 5-15 parts of tripeptide-1 copper, 0.2-0.4 part of NMF-501-3 parts of dipotassium glycyrrhizinate and 1.2-2 parts of sodium hyaluronate. The sheep placenta disclosed by the invention adopts hydrolysis extraction and freeze-drying technologies, so that the active ingredients of the sheep placenta are fully maintained, and the cosmetic polypeptides and moisturizing factors of modern science and technology are matched, so that the defects of the sheep placenta during the absorption of the sheep placenta are overcome, various obvious aging signs are lightened, fine wrinkles are smoothed, the underlying structure of the skin is improved, the proliferation effect of cells is promoted, the elasticity of the skin is enhanced, and the effect of delaying skin aging is further achieved.
Description
Technical Field
The invention relates to the field of cosmetic additives, in particular to an anti-aging cosmetic additive and a preparation method thereof.
Background
The sheep placenta has the most similar structure and components to human placenta and has high nutritive value. The sheep placenta contains a large amount of bioactive factors such as epidermal growth factor, hyaluronic acid stimulating factor and the like, and various enzymes, amino acids, mineral elements and the like for promoting and improving tissue metabolism. The sheep placenta extract contains micromolecular polypeptide as main component, has the functions of improving immunity of organism, resisting aging, resisting cancer and the like, and is widely applied to the fields of medical care, food, cosmetics and the like.
Based on the risk and high cost of the current sheep placenta injection method, people consider more about adding sheep placenta extract into cosmetics for external application to achieve the effects of skin rejuvenation and anti-aging. Therefore, it is very necessary to develop an easily absorbable and effective anti-aging cosmetic based on the sheep placenta extract.
Disclosure of Invention
In order to overcome the problems in the background technology, the invention provides an anti-aging cosmetic additive and a preparation method thereof, wherein sheep placenta adopts hydrolysis extraction and freeze-drying technology, active ingredients of sheep placenta are fully maintained, and beauty polypeptides and moisturizing factors of modern science and technology are matched, so that the defects of the sheep placenta during epidermal absorption are improved, various obvious aging signs are lightened, fine wrinkles are smoothed, the underlying structure of skin is improved, the proliferation effect of cells is promoted, the elasticity of the skin is enhanced, and the effect of delaying skin aging is achieved.
In order to realize the purpose, the invention is realized by the following technical scheme:
the anti-aging cosmetic additive comprises the following components: hydrolyzed placenta (sheep) extract, palmitoyl tripeptide-1, palmitoyl pentapeptide-4, carnosine, and tripeptide-1 copper.
Further preferably, the anti-aging cosmetic additive further comprises the following components: NMF-50, dipotassium glycyrrhizinate and sodium hyaluronate.
Further preferably, the anti-aging cosmetic additive comprises the following components in percentage by weight:
the preparation method of the anti-aging cosmetic additive specifically comprises the following steps:
1) weighing raw materials at a certain proportion, stirring sodium hyaluronate and dipotassium glycyrrhizinate, heating to 75-85 deg.C, and stirring for 4-6 min;
2) when the temperature is reduced to 55-60 ℃, adding NMF-50, stirring and cooling;
3) cooling to 40-45 deg.C, sequentially adding palmitoyl tripeptide-1, palmitoyl pentapeptide-4, carnosine, tripeptide-1 copper and hydrolyzed placenta hominis (sheep) extract, stirring, homogenizing, and cooling to room temperature.
Further preferably, the preparation of the hydrolyzed placenta (sheep) extract comprises the steps of:
1) cleaning and crushing sheep placenta as a raw material;
2) performing ultrasonic pretreatment on the crushed sheep placenta, adding a proper amount of purified water, papain and flavourzyme, hydrolyzing for 10-12h at 45-55 ℃, and filtering to obtain sheep placenta hydrolysate;
3) freeze-drying the sheep placenta hydrolysate obtained in the step 2) to obtain a hydrolyzed placenta (sheep) extract.
Further preferably, in the step 2), the ultrasonic pretreatment refers to ultrasonic treatment for 15-20min at the temperature of 25-30 ℃ and the power of 360-.
More preferably, in the step 2), the adding amount of the papain and the flavor enzyme is 6000U/g.
The invention has the beneficial effects that:
the sheep placenta disclosed by the invention adopts hydrolysis extraction and freeze-drying technologies, fully maintains active ingredients of sheep placenta, is matched with beauty polypeptide and moisturizing factors in modern science and technology, overcomes the defects of the sheep placenta when the sheep placenta is absorbed by the epidermis, quickly enters the dermis layer through skin capillaries, effectively improves the microcirculation capacity and activates cell renewal.
The anti-aging cosmetic additive is scientific and reasonable in preparation, generates a synergistic effect by compounding the active ingredients, is beneficial to fading various remarkable aging signs, is beneficial to smoothing fine wrinkles and improving the bottom layer structure of skin; promoting cell proliferation, promoting collagen production, filling skin tissue, synthesizing more elastin, enhancing skin elasticity, and delaying skin aging. The anti-aging additive can be added into skin care products such as emulsion, skin cream and the like, and has wide application range.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, preferred embodiments of the present invention will be described in detail below to facilitate understanding of the skilled person.
Hydrolyzed placenta (sheep) extract: the active factor contained in the composition can promote the proliferation of cells in vivo and delay skin aging. Tripeptide-1 copper: repairing injury, promoting reconstruction of damaged collagen, repairing scar and wrinkle abnormal collagen fiber, and promoting wound healing. Palmitoyl tripeptide-1: promoting collagen whitening, filling skin tissue to reduce facial wrinkle, increasing skin water content, and improving skin color. Palmitoyl pentapeptide-4: promote the skin to synthesize more elastin, thereby reducing wrinkles and improving the skin elasticity. Carnosine: the stabilizer and protector of cell membrane can prevent free radical damage, protect lipid material of cell membrane, and scavenge free radical. The hydrolyzed sheep placenta extract, NMF-50 and sodium hyaluronate cooperate to effectively improve microcirculation ability, activate cell renewal and improve the defects of the hydrolyzed sheep placenta extract when the epidermis is absorbed.
Example 1
An anti-aging cosmetic additive comprises the following components in parts by weight: 3 parts of hydrolyzed placenta (sheep) extract, 14 parts of palmitoyl tripeptide, 45 parts of palmitoyl pentapeptide, 3 parts of carnosine, 10 parts of tripeptide-1 copper, 502 parts of NMF-502 parts, 0.2 part of dipotassium glycyrrhizinate and 2 parts of sodium hyaluronate.
The preparation method specifically comprises the following steps:
1) preparation of hydrolyzed placenta (sheep) extract:
a. using sheep placenta as raw material, cleaning, pulverizing (fineness is 200 meshes);
b. subjecting pulverized placenta caprae seu ovis to ultrasonic treatment at 28 deg.C and power of 420W for 18min, adding appropriate amount of purified water and simultaneously adding 6000U/g papain and 6000U/g flavor enzyme, hydrolyzing at 50 deg.C for 12 hr, and filtering to obtain placenta caprae seu ovis hydrolysate; (degree of hydrolysis 22.30%)
c. And d, freeze-drying the sheep placenta hydrolysate obtained in the step b to obtain a hydrolyzed placenta (sheep) extract.
2) Weighing raw materials at a certain proportion, stirring sodium hyaluronate and dipotassium glycyrrhizinate, heating to 75-85 deg.C, and stirring for 5 min;
3) when the temperature is reduced to 55-60 ℃, adding NMF-50, stirring and cooling;
4) cooling to 40-45 deg.C, sequentially adding palmitoyl tripeptide-1, palmitoyl pentapeptide-4, carnosine, tripeptide-1 copper and hydrolyzed placenta hominis (sheep) extract, stirring, homogenizing, and cooling to room temperature.
Example 2
An anti-aging cosmetic additive comprises the following components in parts by weight: 2 parts of hydrolyzed placenta (sheep) extract, 13 parts of palmitoyl tripeptide, 46 parts of palmitoyl pentapeptide, 3 parts of carnosine, 12 parts of tripeptide-1 copper, NMF-503 parts, 0.3 part of dipotassium glycyrrhizinate and 2 parts of sodium hyaluronate.
The preparation method specifically comprises the following steps:
1) preparation of hydrolyzed placenta (sheep) extract:
a. using sheep placenta as raw material, cleaning, pulverizing (fineness is 180 meshes);
b. carrying out ultrasonic treatment on the crushed sheep placenta for 15min at the temperature of 30 ℃ and the power of 360W, adding a proper amount of purified water, adding 6000U/g papain and 6000U/g flavor enzyme at the same time, hydrolyzing for 12h at the temperature of 48 ℃, and filtering to obtain sheep placenta hydrolysate; (degree of hydrolysis 20.56%)
c. And d, freeze-drying the sheep placenta hydrolysate obtained in the step b to obtain a hydrolyzed placenta (sheep) extract.
2) Weighing raw materials at a certain proportion, stirring sodium hyaluronate and dipotassium glycyrrhizinate, heating to 75-85 deg.C, and stirring for 5 min;
3) when the temperature is reduced to 55-60 ℃, adding NMF-50, stirring and cooling;
4) cooling to 40-45 deg.C, sequentially adding palmitoyl tripeptide-1, palmitoyl pentapeptide-4, carnosine, tripeptide-1 copper and hydrolyzed placenta hominis (sheep) extract, stirring, homogenizing, and cooling to room temperature.
Example 3
An anti-aging cosmetic additive comprises the following components in parts by weight: 4 parts of hydrolyzed placenta (sheep) extract, 10.3 parts of palmitoyl tripeptide, 43 parts of palmitoyl pentapeptide, 2 parts of carnosine, 15 parts of tripeptide-1 copper, 501 parts of NMF-501 parts, 0.4 part of dipotassium glycyrrhizinate and 1.2 parts of sodium hyaluronate.
The preparation method specifically comprises the following steps:
1) preparation of hydrolyzed placenta (sheep) extract:
a. using sheep placenta as raw material, cleaning, pulverizing (fineness is 80 meshes);
b. subjecting pulverized placenta caprae seu ovis to ultrasonic treatment at 25 deg.C and power of 450W for 20min, adding appropriate amount of purified water and simultaneously adding 6000U/g papain and 6000U/g flavor enzyme, hydrolyzing at 55 deg.C for 10 hr, and filtering to obtain placenta caprae seu ovis hydrolysate; (degree of hydrolysis 19.86%)
c. And d, freeze-drying the sheep placenta hydrolysate obtained in the step b to obtain a hydrolyzed placenta (sheep) extract.
2) Weighing raw materials at a certain proportion, stirring sodium hyaluronate and dipotassium glycyrrhizinate, heating to 75-85 deg.C, and stirring for 6 min;
3) when the temperature is reduced to 55-60 ℃, adding NMF-50, stirring and cooling;
4) cooling to 40-45 deg.C, sequentially adding palmitoyl tripeptide-1, palmitoyl pentapeptide-4, carnosine, tripeptide-1 copper and hydrolyzed placenta hominis (sheep) extract, stirring, homogenizing, and cooling to room temperature.
Evaluation of efficacy
The anti-aging additives prepared in examples 1 to 3 were added to the same type of emulsion, respectively, and the anti-aging efficacy and the skin feel were evaluated by human body tests.
A female subject of 25 persons is selected, of which 23-30 years old 12 persons, 30-40 years old 13 persons. The subject did not apply additional skin care to the test site within approximately 2 months. The test temperature is 35 ℃ and the humidity is 40-50%. The test areas are spaced at 1cm intervals, each test area is 3cm x 3cm, and the ratio is 2mg/cm2The latex is weighed, and is evenly smeared in a test area by using a latex glove, and the measurement is carried out after 15 minutes.
(1) Measurement of the water content of the stratum corneum of the skin: the moisture was tested by capacitance.
(2) Skin elasticity test: the skin elasticity tester adopts a suction method to test the elasticity.
(3) And (3) fading fine grain testing: the reduction of the fine lines around the eyes of the subject 2 months before and after the administration of the emulsion was compared by direct measurement.
Test results and evaluation
(1) Determination of the Water content of the stratum corneum
The effect of the emulsions applied with the additives of examples 1-3 on the water content of the stratum corneum within 60 days was measured using a skin moisture test probe and is shown in Table 1.
TABLE 1
The average moisture content on the inner side of the arm was 26, and the moisture content of the stratum corneum did not change much in the case of the lotion of the blank group (without the anti-aging cosmetic additive) for 60 days, but the moisture content of the stratum corneum significantly increased when the lotion of any of examples 1-2 was used.
(2) Skin elasticity test
The effect of the emulsions of examples 1-3 with the additives on skin elasticity over a period of 60 days was measured using the skin moisture test probe and is shown in Table 2.
TABLE 2
When the subject did not use the emulsion, the average forearm elasticity parameter was 0.5, and the skin elasticity was significantly increased using the emulsions of examples 1, 2 or 3.
(3) Fade fine line test
The emulsion added with the anti-aging additive has different fine line fading effects within 2 months for 25 subjects. After the skin of a 23-30-year-old subject is used, fine wrinkles can be effectively prevented from being generated on the basis of high-efficiency moisture retention, the fine wrinkles are obviously reduced, the skin around the eyes is improved, and no fat particles are generated. After the test subject of 30-40 years old uses the skin-care product, the skin-care product can deeply moisturize and nourish the skin, repair and fill fine wrinkles around eyes, and the fine wrinkles on the skin are obviously faded, compacted and elastic after the skin-care product is used.
The additive has synergistic effect of sheep placenta, skin caring polypeptide, and moisturizing factor, and can resist oxidative damage of free radicals to cells and bioactive macromolecules, accelerate differentiation and proliferation of surface cells, delay apoptosis, enhance skin immunity, and improve skin microcirculation. The emulsion containing the additive can be continuously used for repairing damaged skin and reducing eye wrinkles.
Finally, it is noted that the above-mentioned preferred embodiments illustrate rather than limit the invention, and that, although the invention has been described in detail with reference to the above-mentioned preferred embodiments, it will be understood by those skilled in the art that various changes in form and detail may be made therein without departing from the scope of the invention as defined by the appended claims.
Claims (7)
1. An anti-aging cosmetic additive, which is characterized in that: comprises the following components: hydrolyzed placenta (sheep) extract, palmitoyl tripeptide-1, palmitoyl pentapeptide-4, carnosine, and tripeptide-1 copper.
2. The anti-aging cosmetic additive according to claim 1, wherein: the anti-aging cosmetic additive also comprises the following components: NMF-50, dipotassium glycyrrhizinate and sodium hyaluronate.
3. The anti-aging cosmetic additive according to claim 2, wherein: the paint comprises the following components in percentage by weight:
hydrolyzed placenta (sheep) extract 1-4 parts
Palmitoyl tripeptide-10.5-5 parts
Palmitoyl pentapeptide-43-6 parts
1-3 parts of carnosine
Tripeptide-1 copper 5-15 parts
NMF-501-3 parts
0.2-0.4 part of dipotassium glycyrrhizinate
1.2-2 parts of sodium hyaluronate.
4. The method for preparing an antiaging cosmetic additive according to any one of claims 2-3, characterized in that: the method specifically comprises the following steps:
1) weighing raw materials at a certain proportion, stirring sodium hyaluronate and dipotassium glycyrrhizinate, heating to 75-85 deg.C, and stirring for 4-6 min;
2) when the temperature is reduced to 55-60 ℃, adding NMF-50, stirring and cooling;
3) cooling to 40-45 deg.C, sequentially adding palmitoyl tripeptide-1, palmitoyl pentapeptide-4, carnosine, tripeptide-1 copper and hydrolyzed placenta hominis (sheep) extract, stirring, homogenizing, and cooling to room temperature.
5. The method of preparing an anti-aging cosmetic additive according to claim 4, wherein: preparation of hydrolyzed placenta (sheep) extract comprises the following steps:
1) cleaning and crushing sheep placenta as a raw material;
2) performing ultrasonic pretreatment on the crushed sheep placenta, adding a proper amount of purified water, papain and flavourzyme, hydrolyzing for 10-12h at 45-55 ℃, and filtering to obtain sheep placenta hydrolysate;
3) freeze-drying the sheep placenta hydrolysate obtained in the step 2) to obtain a hydrolyzed placenta (sheep) extract.
6. The method of preparing an anti-aging cosmetic additive according to claim 5, wherein: in the step 2), the ultrasonic pretreatment refers to ultrasonic treatment for 15-20min at the temperature of 25-30 ℃ and the power of 360-.
7. The method for preparing an anti-aging cosmetic additive according to claim 5 or 6, wherein: in the step 2), the adding amount of the papain and the flavor enzyme is 6000U/g.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910983398.8A CN110585111A (en) | 2019-10-16 | 2019-10-16 | Anti-aging cosmetic additive and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910983398.8A CN110585111A (en) | 2019-10-16 | 2019-10-16 | Anti-aging cosmetic additive and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110585111A true CN110585111A (en) | 2019-12-20 |
Family
ID=68867574
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910983398.8A Pending CN110585111A (en) | 2019-10-16 | 2019-10-16 | Anti-aging cosmetic additive and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110585111A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111494287A (en) * | 2020-03-25 | 2020-08-07 | 国健菁华(深圳)精准健康科技有限公司 | Skin-whitening anti-aging beauty lotion composition Rufuyin and preparation method thereof |
| CN112870096A (en) * | 2021-03-11 | 2021-06-01 | 成都雅婷化妆品有限公司 | Anti-aging skin-tendering essence and preparation method thereof |
| CN114376958A (en) * | 2022-02-18 | 2022-04-22 | 奥珀莱健康产业科技(广州)有限公司 | Anti-aging placenta essence stock solution and preparation method thereof |
| CN117503675A (en) * | 2023-03-22 | 2024-02-06 | 广州准优生物科技有限公司 | Preparation method of hydrolyzed sheep placenta extract and its application in cosmetics |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107823095A (en) * | 2017-12-07 | 2018-03-23 | 安徽生物肽产业研究院有限公司 | A kind of active peptide facial mask |
| CN107898811A (en) * | 2017-12-20 | 2018-04-13 | 申正军 | A kind of preparation process for hydrolyzing frozen dry powder of sheep placenta |
| CN109464342A (en) * | 2018-12-29 | 2019-03-15 | 广州市盛美化妆品有限公司 | A kind of anti-aging Essence and preparation method thereof |
| CN109589297A (en) * | 2019-01-09 | 2019-04-09 | 广州灵润生物科技有限公司 | A kind of fullerene sodium hyaluronate polypeptide MASQUE APAISANT HYDRATANT |
| CN109984952A (en) * | 2017-12-29 | 2019-07-09 | 广州佳洁化妆品有限公司 | A kind of Essence and preparation method of the compounding removing wrinkle and resisting aging containing a variety of small-molecule peptides |
-
2019
- 2019-10-16 CN CN201910983398.8A patent/CN110585111A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107823095A (en) * | 2017-12-07 | 2018-03-23 | 安徽生物肽产业研究院有限公司 | A kind of active peptide facial mask |
| CN107898811A (en) * | 2017-12-20 | 2018-04-13 | 申正军 | A kind of preparation process for hydrolyzing frozen dry powder of sheep placenta |
| CN109984952A (en) * | 2017-12-29 | 2019-07-09 | 广州佳洁化妆品有限公司 | A kind of Essence and preparation method of the compounding removing wrinkle and resisting aging containing a variety of small-molecule peptides |
| CN109464342A (en) * | 2018-12-29 | 2019-03-15 | 广州市盛美化妆品有限公司 | A kind of anti-aging Essence and preparation method thereof |
| CN109589297A (en) * | 2019-01-09 | 2019-04-09 | 广州灵润生物科技有限公司 | A kind of fullerene sodium hyaluronate polypeptide MASQUE APAISANT HYDRATANT |
Non-Patent Citations (1)
| Title |
|---|
| 北京昂立达技术有限公司研发部: ""氨基酸保湿剂在个人护理品中的应用(NMF—50)"", 《中国化妆品》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111494287A (en) * | 2020-03-25 | 2020-08-07 | 国健菁华(深圳)精准健康科技有限公司 | Skin-whitening anti-aging beauty lotion composition Rufuyin and preparation method thereof |
| CN112870096A (en) * | 2021-03-11 | 2021-06-01 | 成都雅婷化妆品有限公司 | Anti-aging skin-tendering essence and preparation method thereof |
| CN114376958A (en) * | 2022-02-18 | 2022-04-22 | 奥珀莱健康产业科技(广州)有限公司 | Anti-aging placenta essence stock solution and preparation method thereof |
| CN117503675A (en) * | 2023-03-22 | 2024-02-06 | 广州准优生物科技有限公司 | Preparation method of hydrolyzed sheep placenta extract and its application in cosmetics |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN106963661B (en) | Hexagon firming essence liquid and preparation method thereof | |
| CN109330964A (en) | A kind of anti-ageing anti-wrinkle composition and its preparation method and application | |
| CN110585111A (en) | Anti-aging cosmetic additive and preparation method thereof | |
| CN111035609A (en) | Micromolecular polypeptide eye essence and preparation method thereof | |
| CN104856892A (en) | Cosmetic or skin care product preparation rich in growth factors and preparation method therefor | |
| CN113576975B (en) | Easily-absorbed anti-aging composition and preparation method and application thereof | |
| CN111297727A (en) | Beautifying and plasticizing treatment composition and application thereof | |
| CN103948525B (en) | Anti-aging active composition for epidermis | |
| CN113768853B (en) | Whitening and freckle-removing composition, and preparation method and application thereof | |
| CN110538093A (en) | polypeptide repair liquid and preparation method thereof | |
| CN107661269A (en) | A kind of nontoxic nail saver for repairing nail and preparation method thereof | |
| KR20190010795A (en) | Moisturizing, anti-wrinkling, and whitening cosmetic composition comprising novel Hyalpol Matrix Mixture and preparation method of the same | |
| KR101697152B1 (en) | Manufacturing method of cosmetic material having an anti-aging effect using mucin from eel skin | |
| CN111035590A (en) | Micromolecule polypeptide youth essence and preparation method thereof | |
| CN110496067A (en) | A kind of anti-wrinkle composition and its preparation method and application | |
| CN115957149A (en) | Shuiguang needle essence and preparation method thereof | |
| KR101917026B1 (en) | Cosmetic composition for skin wrinkle improvement and prevention | |
| CN111568781A (en) | Skin care gel and preparation method thereof | |
| CN107854344A (en) | A kind of Essence and preparation method thereof | |
| CN113318004A (en) | Repair essence and preparation method thereof | |
| CN111728919A (en) | Firming and wrinkle-removing essence and preparation method thereof | |
| RU2667130C1 (en) | Chitosan-containing hydrogel and method of cosmetic skin care with it use | |
| RU2805144C1 (en) | Recombinant angiogenin in cosmetic and pharmaceutical compositions | |
| CN112294683A (en) | Cosmetic with epidermis moisturizing and skin anti-wrinkle effects and preparation and application thereof | |
| CN111514060B (en) | Liquid foundation with moisturizing and anti-aging effects |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20191220 |