CN110785664A - 流产中的特征性代谢物 - Google Patents

流产中的特征性代谢物 Download PDF

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Publication number
CN110785664A
CN110785664A CN201880042548.9A CN201880042548A CN110785664A CN 110785664 A CN110785664 A CN 110785664A CN 201880042548 A CN201880042548 A CN 201880042548A CN 110785664 A CN110785664 A CN 110785664A
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CN
China
Prior art keywords
carnitine
metabolite
compared
concentration
control
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201880042548.9A
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English (en)
Chinese (zh)
Inventor
T·C·陈
C·W·古
N·S·陈
Z·W·陈
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanyang Technological University
Singapore Health Services Pte Ltd
Original Assignee
Nanyang Technological University
Singapore Health Services Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanyang Technological University, Singapore Health Services Pte Ltd filed Critical Nanyang Technological University
Publication of CN110785664A publication Critical patent/CN110785664A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/743—Steroid hormones
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/36—Gynecology or obstetrics
    • G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/493—Physical analysis of biological material of liquid biological material urine

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN201880042548.9A 2017-04-28 2018-04-30 流产中的特征性代谢物 Pending CN110785664A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SG10201703502T 2017-04-28
SG10201703502T 2017-04-28
PCT/SG2018/050208 WO2018199849A1 (fr) 2017-04-28 2018-04-30 Métabolites caractéristiques dans des fausses couches

Publications (1)

Publication Number Publication Date
CN110785664A true CN110785664A (zh) 2020-02-11

Family

ID=63917738

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201880042548.9A Pending CN110785664A (zh) 2017-04-28 2018-04-30 流产中的特征性代谢物

Country Status (3)

Country Link
CN (1) CN110785664A (fr)
SG (1) SG11201909977PA (fr)
WO (1) WO2018199849A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019139543A1 (fr) 2018-01-15 2019-07-18 Nanyang Technological University Plateforme superhydrophobe destinée à détecter des métabolites et des toxines dans l'urine

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140221236A1 (en) * 2013-02-01 2014-08-07 Kristi S. Borowski Metabolomic markers for preterm birth

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5786220A (en) * 1995-04-28 1998-07-28 Quidel Corporation Assays and devices for distinguishing between normal and abnormal pregnancy
US20150090010A1 (en) * 2013-09-27 2015-04-02 Chang Gung University Method for diagnosing heart failure
GB201317458D0 (en) * 2013-10-02 2013-11-13 Spd Swiss Prec Diagnostics Gmbh Improved pregnancy test device and method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140221236A1 (en) * 2013-02-01 2014-08-07 Kristi S. Borowski Metabolomic markers for preterm birth

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CECIL A. LONG ET AL.: "First-trimester rapid semiquantitative assay for urine pregnanediol glucuronide predicts gestational outcome with the same diagnostic accuracy as serial human chorionic gonadotropin measurements", 《AM J OBSTET GYNECOL》 *
CHEE WAI KU ET AL.: "Spontaneous miscarriage in first trimester pregnancy is associated with altered urinary metabolite profile", 《BBA CLINICAL》 *
谢春红 等: "基于气相色谱一质谱技术的代谢组学方法发现复发性流产标记物的研究", 《实用妇产科杂志》 *

Also Published As

Publication number Publication date
WO2018199849A1 (fr) 2018-11-01
SG11201909977PA (en) 2019-11-28

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Application publication date: 20200211