CN111973473A - Preservative for cosmetics and preparation method thereof - Google Patents

Abstract

The invention discloses a cosmetic preservative and a preparation method thereof. The preservative is composed of the following components in percentage by weight: thymol 10-40%, carvacrol salt 20-70%, ethyl cellulose 1‑20%, methylcellulose 1‑20%, plasticizer 2‑10% and stabilizer 0.5‑20%. The invention belongs to the technical field of cosmetics, and provides a cosmetic preservative and a preparation method thereof. The preservative has excellent antibacterial effect and is mild to the skin so that it can be used as an antibacterial agent for skin care products, and the preparation method has steps Simple and easy to get the effect of raw materials.

Description

A kind of cosmetic preservative and preparation method thereof

technical field

The invention belongs to the technical field of cosmetics, in particular to a cosmetic preservative and a preparation method thereof.

Background technique

With the improvement of people's living standards and the pursuit of beauty, cosmetics have become a necessity and are more and more favored by people, especially women. Cosmetics refers to chemical industrial products or fine chemical products that clean, maintain, beautify, modify, change appearance, correct human odor, and maintain good condition on human surfaces such as skin, hair, nails, lips and teeth by smearing and spraying. Cosmetic ingredients mainly include matrix raw materials and additives. The matrix is the basic raw material of cosmetics and plays a major role, including oils, waxes and powdery raw materials. composition, etc. Cosmetic preservatives refer to substances that have a sustained inhibitory effect on the growth of microorganisms. As we all know, cosmetics contain a lot of nutrients and moisture. During the production and use process, microorganisms will grow and multiply in large quantities, absorbing, decomposing and destroying the effective ingredients in cosmetics. Therefore, preservatives are an important part of cosmetics and the main means to prevent microbial contamination of cosmetics. However, the use of preservatives may also cause skin allergies and dermatitis, so the selection and use of cosmetic preservatives must be very careful.

SUMMARY OF THE INVENTION

In order to solve the above-mentioned existing problems, the present invention provides a cosmetic preservative and a preparation method thereof. The preservative has excellent antibacterial effect and is mild to the skin, so that it can be used as an antibacterial agent for skin care products, and the preparation method has the advantages of The process is simple and the raw materials are easy to obtain the effect.

The technical scheme adopted in the present invention is as follows: the present invention provides a cosmetic preservative, which is composed of the following components in weight percentage: thymol 10-40%, carvacrol salt 20-70%, ethyl fiber 1-20% cellulose, 1-20% methyl cellulose, 2-10% plasticizer and 0.5-20% stabilizer.

Further, the thymol and carvacrol salt are active components, and the mass ratio of the two is 1:2-4:3, and thymol can inhibit and inhibit Gram-positive bacteria and Gram-negative bacteria, including Bacillus subtilis. , Escherichia coli, Klebsiella pneumoniae and Staphylococcus aureus, etc. Studies have shown that thymol and disodium carvacrol phosphonate can destroy the integrity of bacterial cell membrane through pH and ion balance after mixing in an appropriate ratio, so as to achieve Good bacteriostatic effect.

Further, the ethyl cellulose and methyl cellulose are coating agents, and the mass ratio of the two is 1:1, because thymol is a white crystal, has the aroma of thyme oil, is soluble in organic solvents such as ethanol, and is slightly soluble. In water and glycerol, in order to increase its solubility, ethyl cellulose and methyl cellulose are used to make thymol encapsulated in a shell at a ratio of 1:1 to obtain ultra-micron-level particles. The obtained granules have good water solubility and stability, and their bacteriostatic effect is similar to that of methylparaben.

Further, the plasticizer is dibutyl sebacate, and the stabilizer is oleic acid.

The present invention also provides a preparation method of the cosmetic preservative, comprising the following steps:

1) After mixing ethyl cellulose and methyl cellulose, add a plasticizer to stir, when it is in a molten state, add stability to form an oil phase system, add an alkaline aqueous solution to pH 7-9, and continue to stir until form a colloid in which water is dispersed in a polymer colloid;

2) adding thymol to the colloid and mixing uniformly, placing the obtained mixture in a fluidized bed for coating at 32-37° C. to obtain ultra-micron-level particles;

3) The obtained granules are mixed with carvacrol salt to obtain the cosmetic preservative.

The beneficial effects that the present invention has:

1. Thymol is a natural ingredient extracted from plant essential oils. It has a certain antiseptic effect and also has nutritional value. It is non-toxic and non-harmful to the human body and can be eaten. It can be added to maternal and infant cosmetics.

2. Carvacrol disodium phosphate is a form in which carvacrol is converted into an organic salt by chemical modification, and has better solubility than carvacrol.

3. Both carvacrol disodium phosphate and thymol alone have antibacterial effects. After mixing the two in proportion, the integrity of the bacterial cell membrane is destroyed by pH and ion balance, and a better antiseptic and antibacterial effect is achieved.

4. The thymol is coated by the sealing technology, so that the thymol can be used in an unmodified state, and the formed shell wraps the ultra-micron-level particles, which has good water solubility and stability.

Detailed ways

The technical solution of the present invention will be described in further detail below with reference to specific implementations. The parts of the technical features or connection relationships described in the present invention that are not described in detail are the prior art used. It should be understood that the specific embodiments described herein are only used to illustrate and explain the present invention, but not to limit the present invention.

The invention provides a cosmetic preservative, which is composed of the following components by weight: 10-40% of thymol, 20-70% of carvacrol salt, 1-20% of ethyl cellulose, methyl cellulose Cellulose 1-20%, plasticizer 2-10% and stabilizer 0.5-20%, its active ingredients include thymol and carvacrol salt, the mass ratio of the two is 1:2-4:3, and the content of the components can be Select within the range, the mass ratio of coating agent ethyl cellulose and methyl cellulose is 1:1, and the specific types of plasticizer and stabilizer can be selected within a wide range, but in order to make the prepared preservative have Excellent dissolving effect, the plasticizer is dibutyl sebacate, and the stabilizer is oleic acid.

The present invention also provides a preparation method of a cosmetic preservative, comprising:

1) After mixing ethyl cellulose and methyl cellulose, add a plasticizer to stir, when it is in a molten state, add stability to form an oil phase system, add a small amount of alkaline aqueous solution to pH 7-9, continue stirring to form a colloid in which water is dispersed in the polymer colloid;

2) adding thymol to the colloid and mixing uniformly, placing the obtained mixture in a fluidized bed for coating at 32-37° C. to obtain ultra-micron-level particles;

3) The obtained granules are mixed with carvacrol salt to obtain the cosmetic preservative.

The present invention will be described in detail below by means of examples.

Example 1

Mix 15g of ethyl cellulose and 15g of methylcellulose, add 8g of diethyl citrate to plasticize, when it is in a molten state, add 20g of emulsified silicone oil to form an oil phase system, and then slowly add an alkaline aqueous solution to pH For 7-9, a colloid of water dispersed in the polymer colloid is formed under stirring. 35 g of thymol was added to the colloid and mixed uniformly, and the obtained mixture was put into a fluidized bed for coating to obtain ultra-micron granules. 50 g of disodium carvacrol phosphate was mixed with the obtained granules to obtain the cosmetic preservative.

Example 2

Mix 20g of ethyl cellulose and 20g of methylcellulose, add 10g of dibutyl sebate to plasticize, add 20g of oleic acid to form an oil phase system when it is in a molten state, and then slowly add an alkaline aqueous solution to pH For 7-9, a colloid of water dispersed in the polymer colloid is formed under stirring. 40 g of thymol was added to the colloid and mixed uniformly, and the obtained mixture was put into a fluidized bed for coating at 35° C. to obtain ultra-micron granules. The obtained granules were mixed with 60 g of disodium carvacrol phosphate to obtain the cosmetic preservative.

Claims (7)

1. The preservative for cosmetics is characterized by comprising the following components in percentage by weight: 10-40% of thymol, 20-70% of carvacrol salt, 1-20% of ethyl cellulose, 1-20% of methyl cellulose, 2-10% of plasticizer and 0.5-20% of stabilizer.

2. A cosmetic preservative according to claim 1, wherein: the plasticizer is dibutyl sebacate.

3. A cosmetic preservative according to claim 2, wherein: the stabilizer is oleic acid.

4. A cosmetic preservative according to claim 3, wherein: the mass ratio of the ethyl cellulose to the methyl cellulose is 1: 1.

5. A cosmetic preservative according to claim 4, wherein: the mass ratio of the thymol to the carvacrol salt is 1:2-4: 3.

6. A cosmetic preservative according to claim 5, wherein: the carvacrol salt is carvacrol disodium phosphate.

7. The method for preparing a cosmetic preservative according to claim 1, wherein the cosmetic preservative comprises:

1) mixing ethyl cellulose and methyl cellulose, adding a plasticizer, stirring, adding a stabilizer to form an oil phase system when the mixture is in a molten state, adding an alkaline aqueous solution until the pH value is 7-9, and continuously stirring until a colloid with water dispersed in a polymer colloid is formed;

2) adding thymol into the colloid, uniformly mixing, and putting the obtained mixture into a fluidized bed for coating at 32-37 ℃ to obtain ultramicro-grade particles;

3) and mixing the obtained granules with carvacrol salt to obtain the preservative for the fruit cosmetics.