CN1121412A - 含胡椒碱的组合物 - Google Patents

含胡椒碱的组合物 Download PDF

Info

Publication number: CN1121412A
Authority: CN; China
Prior art keywords: medicine; piperine; compositions; accounts; content
Prior art date: 1993-10-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

CN94117602A

Other languages

English (en)

Chinese (zh)

Inventor

R·B·帕特尔

I·A·莫迪

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Cadila Laboratories Ltd

Original Assignee

Cadila Laboratories Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-10-29

Filing date

1994-10-28

Publication date

1996-05-01

1993-10-29 Priority to IN356BO1993 priority Critical patent/IN176897B/en

1994-10-18 Priority to US08/324,584 priority patent/US5616593A/en

1994-10-21 Priority to AU75992/94A priority patent/AU686656B2/en

1994-10-24 Priority to ZA948348A priority patent/ZA948348B/xx

1994-10-24 Priority to EP94116731A priority patent/EP0709098A1/en

1994-10-28 Application filed by Cadila Laboratories Ltd filed Critical Cadila Laboratories Ltd

1994-10-28 Priority to CN94117602A priority patent/CN1121412A/zh

1994-10-28 Priority to CA002134610A priority patent/CA2134610A1/en

1996-05-01 Publication of CN1121412A publication Critical patent/CN1121412A/zh

Status Pending legal-status Critical Current

Links

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MXXWOMGUGJBKIW-YPCIICBESA-N piperine Chemical compound C=1C=C2OCOC2=CC=1/C=C/C=C/C(=O)N1CCCCC1 MXXWOMGUGJBKIW-YPCIICBESA-N 0.000 title claims abstract description 62
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229960001156 mitoxantrone Drugs 0.000 description 1
KKZJGLLVHKMTCM-UHFFFAOYSA-N mitoxantrone Chemical compound O=C1C2=C(O)C=CC(O)=C2C(=O)C2=C1C(NCCNCCO)=CC=C2NCCNCCO KKZJGLLVHKMTCM-UHFFFAOYSA-N 0.000 description 1
238000002156 mixing Methods 0.000 description 1
229960005181 morphine Drugs 0.000 description 1
229960002009 naproxen Drugs 0.000 description 1
CMWTZPSULFXXJA-VIFPVBQESA-N naproxen Chemical compound C1=C([C@H](C)C(O)=O)C=CC2=CC(OC)=CC=C21 CMWTZPSULFXXJA-VIFPVBQESA-N 0.000 description 1
230000004719 natural immunity Effects 0.000 description 1
229930014626 natural product Natural products 0.000 description 1
230000007935 neutral effect Effects 0.000 description 1
229960001597 nifedipine Drugs 0.000 description 1
HYIMSNHJOBLJNT-UHFFFAOYSA-N nifedipine Chemical compound COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1C1=CC=CC=C1[N+]([O-])=O HYIMSNHJOBLJNT-UHFFFAOYSA-N 0.000 description 1
239000000041 non-steroidal anti-inflammatory agent Substances 0.000 description 1
AKPLHCDWDRPJGD-UHFFFAOYSA-N nordazepam Chemical compound C12=CC(Cl)=CC=C2NC(=O)CN=C1C1=CC=CC=C1 AKPLHCDWDRPJGD-UHFFFAOYSA-N 0.000 description 1
229960002640 nordazepam Drugs 0.000 description 1
229960001180 norfloxacin Drugs 0.000 description 1
OGJPXUAPXNRGGI-UHFFFAOYSA-N norfloxacin Chemical compound C1=C2N(CC)C=C(C(O)=O)C(=O)C2=CC(F)=C1N1CCNCC1 OGJPXUAPXNRGGI-UHFFFAOYSA-N 0.000 description 1
229960001699 ofloxacin Drugs 0.000 description 1
239000008601 oleoresin Substances 0.000 description 1
229940127234 oral contraceptive Drugs 0.000 description 1
239000003539 oral contraceptive agent Substances 0.000 description 1
LSQZJLSUYDQPKJ-UHFFFAOYSA-N p-Hydroxyampicillin Natural products O=C1N2C(C(O)=O)C(C)(C)SC2C1NC(=O)C(N)C1=CC=C(O)C=C1 LSQZJLSUYDQPKJ-UHFFFAOYSA-N 0.000 description 1
229940056367 penicillin v Drugs 0.000 description 1
239000003208 petroleum Substances 0.000 description 1
239000000546 pharmaceutical excipient Substances 0.000 description 1
239000000825 pharmaceutical preparation Substances 0.000 description 1
BPLBGHOLXOTWMN-MBNYWOFBSA-N phenoxymethylpenicillin Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)COC1=CC=CC=C1 BPLBGHOLXOTWMN-MBNYWOFBSA-N 0.000 description 1
150000003053 piperidines Chemical class 0.000 description 1
229960002702 piroxicam Drugs 0.000 description 1
QYSPLQLAKJAUJT-UHFFFAOYSA-N piroxicam Chemical compound OC=1C2=CC=CC=C2S(=O)(=O)N(C)C=1C(=O)NC1=CC=CC=N1 QYSPLQLAKJAUJT-UHFFFAOYSA-N 0.000 description 1
229960003171 plicamycin Drugs 0.000 description 1
229960005179 primaquine Drugs 0.000 description 1
INDBQLZJXZLFIT-UHFFFAOYSA-N primaquine Chemical compound N1=CC=CC2=CC(OC)=CC(NC(C)CCCN)=C21 INDBQLZJXZLFIT-UHFFFAOYSA-N 0.000 description 1
CPTBDICYNRMXFX-UHFFFAOYSA-N procarbazine Chemical compound CNNCC1=CC=C(C(=O)NC(C)C)C=C1 CPTBDICYNRMXFX-UHFFFAOYSA-N 0.000 description 1
229960000624 procarbazine Drugs 0.000 description 1
230000001915 proofreading effect Effects 0.000 description 1
238000010298 pulverizing process Methods 0.000 description 1
238000000746 purification Methods 0.000 description 1
229940117820 purinethol Drugs 0.000 description 1
229960000948 quinine Drugs 0.000 description 1
239000012744 reinforcing agent Substances 0.000 description 1
230000029058 respiratory gaseous exchange Effects 0.000 description 1
235000009566 rice Nutrition 0.000 description 1
229960003440 semustine Drugs 0.000 description 1
238000003756 stirring Methods 0.000 description 1
229960001052 streptozocin Drugs 0.000 description 1
ZSJLQEPLLKMAKR-GKHCUFPYSA-N streptozocin Chemical compound O=NN(C)C(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O ZSJLQEPLLKMAKR-GKHCUFPYSA-N 0.000 description 1
229960004673 sulfadoxine Drugs 0.000 description 1
JLKIGFTWXXRPMT-UHFFFAOYSA-N sulphamethoxazole Chemical compound O1C(C)=CC(NS(=O)(=O)C=2C=CC(N)=CC=2)=N1 JLKIGFTWXXRPMT-UHFFFAOYSA-N 0.000 description 1
229960001603 tamoxifen Drugs 0.000 description 1
230000009967 tasteless effect Effects 0.000 description 1
NRUKOCRGYNPUPR-QBPJDGROSA-N teniposide Chemical compound COC1=C(O)C(OC)=CC([C@@H]2C3=CC=4OCOC=4C=C3[C@@H](O[C@H]3[C@@H]([C@@H](O)[C@@H]4O[C@@H](OC[C@H]4O3)C=3SC=CC=3)O)[C@@H]3[C@@H]2C(OC3)=O)=C1 NRUKOCRGYNPUPR-QBPJDGROSA-N 0.000 description 1
229960001278 teniposide Drugs 0.000 description 1
229960001712 testosterone propionate Drugs 0.000 description 1
230000001225 therapeutic effect Effects 0.000 description 1
231100001274 therapeutic index Toxicity 0.000 description 1
229960002784 thioridazine Drugs 0.000 description 1
229960003087 tioguanine Drugs 0.000 description 1
MNRILEROXIRVNJ-UHFFFAOYSA-N tioguanine Chemical compound N1C(N)=NC(=S)C2=NC=N[C]21 MNRILEROXIRVNJ-UHFFFAOYSA-N 0.000 description 1
239000012049 topical pharmaceutical composition Substances 0.000 description 1
229960005486 vaccine Drugs 0.000 description 1
229960003048 vinblastine Drugs 0.000 description 1
JXLYSJRDGCGARV-XQKSVPLYSA-N vincaleukoblastine Chemical compound C([C@@H](C[C@]1(C(=O)OC)C=2C(=CC3=C([C@]45[C@H]([C@@]([C@H](OC(C)=O)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(=O)OC)N3C)C=2)OC)C[C@@](C2)(O)CC)N2CCC2=C1NC1=CC=CC=C21 JXLYSJRDGCGARV-XQKSVPLYSA-N 0.000 description 1
229960004528 vincristine Drugs 0.000 description 1
OGWKCGZFUXNPDA-UHFFFAOYSA-N vincristine Natural products C1C(CC)(O)CC(CC2(C(=O)OC)C=3C(=CC4=C(C56C(C(C(OC(C)=O)C7(CC)C=CCN(C67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)CN1CCC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-UHFFFAOYSA-N 0.000 description 1
OGWKCGZFUXNPDA-XQKSVPLYSA-N vincristine Chemical compound C([N@]1C[C@@H](C[C@]2(C(=O)OC)C=3C(=CC4=C([C@]56[C@H]([C@@]([C@H](OC(C)=O)[C@]7(CC)C=CCN([C@H]67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)C[C@@](C1)(O)CC)CC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-XQKSVPLYSA-N 0.000 description 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

CN94117602A 1993-10-29 1994-10-28 含胡椒碱的组合物 Pending CN1121412A (zh)

Priority Applications (7)

Application Number	Priority Date	Filing Date	Title
IN356BO1993 IN176897B (2)	1993-10-29	1993-10-29
US08/324,584 US5616593A (en)	1993-10-29	1994-10-18	Compositions containing piperine
AU75992/94A AU686656B2 (en)	1993-10-29	1994-10-21	Compositions containing piperine
ZA948348A ZA948348B (en)	1993-10-29	1994-10-24	compositions containing piperine
EP94116731A EP0709098A1 (en)	1993-10-29	1994-10-24	Compositions containing piperine
CN94117602A CN1121412A (zh)	1993-10-29	1994-10-28	含胡椒碱的组合物
CA002134610A CA2134610A1 (en)	1993-10-29	1994-10-28	Compositions containing piperine

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IN356BO1993 IN176897B (2)	1993-10-29	1993-10-29
CN94117602A CN1121412A (zh)	1993-10-29	1994-10-28	含胡椒碱的组合物

Publications (1)

Publication Number	Publication Date
CN1121412A true CN1121412A (zh)	1996-05-01

Family

ID=37087796

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CN94117602A Pending CN1121412A (zh)	1993-10-29	1994-10-28	含胡椒碱的组合物

Country Status (7)

Country	Link
US (1)	US5616593A (2)
EP (1)	EP0709098A1 (2)
CN (1)	CN1121412A (2)
AU (1)	AU686656B2 (2)
CA (1)	CA2134610A1 (2)
IN (1)	IN176897B (2)
ZA (1)	ZA948348B (2)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN111246847A (zh) *	2017-08-25	2020-06-05	聪明智商股份有限公司	包含植物营养素和适应原草药的功能性咀嚼胶
CN111565721A (zh) *	2017-09-19	2020-08-21	西普拉有限公司	具有增强的生物利用度的包含依鲁替尼和生物碱的组合物

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IN186315B (2) *	1996-12-12	2001-08-04	Panacea Biotec Ltd
GT199800127A (es) *	1997-08-29	2000-02-01		Combinaciones terapeuticas.
TR200000562T2 (tr) *	1997-08-29	2000-08-21	Pfizer Products Inc.	Amlodifin ve bir statin bileşiği içeren bileşim terapisi
US5916595A (en) *	1997-12-12	1999-06-29	Andrx Pharmaceutials, Inc.	HMG co-reductase inhibitor
US20060141036A1 (en) *	1997-12-12	2006-06-29	Andrx Labs Llc	HMG-CoA reductase inhibitor extended release formulation
US20040029962A1 (en) *	1997-12-12	2004-02-12	Chih-Ming Chen	HMG-COA reductase inhibitor extended release formulation
EP0935964A1 (en) *	1998-02-12	1999-08-18	Panacea Biotec Limited	Pharmaceutical compositions containing NSAIDs and piperine
GB9812426D0 (en)	1998-06-10	1998-08-05	Reckitt & Colmann Prod Ltd	Improvements in or relating to organic compositions
US6524620B2 (en)	1998-07-20	2003-02-25	Andrx Pharmaceuticals, Inc.	Diltiazem controlled release formulation and method of manufacture
US6054585A (en) *	1998-12-23	2000-04-25	Sabinsa Corporation	Process for making high purity piperine for nutritional use
US6262085B1 (en)	1999-08-26	2001-07-17	Robert R. Whittle	Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6268385B1 (en)	1999-08-26	2001-07-31	Robert R. Whittle	Dry blend pharmaceutical formulations
US6316020B1 (en)	1999-08-26	2001-11-13	Robert R. Whittle	Pharmaceutical formulations
US6369087B1 (en)	1999-08-26	2002-04-09	Robert R. Whittle	Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6326384B1 (en)	1999-08-26	2001-12-04	Robert R. Whittle	Dry blend pharmaceutical unit dosage form
US6312723B1 (en)	1999-08-26	2001-11-06	Robert R. Whittle	Pharmaceutical unit dosage form
US6262086B1 (en)	1999-08-26	2001-07-17	Robert R. Whittle	Pharmaceutical unit dosage form
US6780880B1 (en)	1999-08-26	2004-08-24	Robert R. Whittle	FT-Raman spectroscopic measurement
US6312712B1 (en)	1999-08-26	2001-11-06	Robert R. Whittle	Method of improving bioavailability
AU768950B2 (en) *	1999-11-08	2004-01-08	Andrx Corporation	HMG-COA reductase inhibitor extended release formulation
IL141438A0 (en) *	2000-02-23	2002-03-10	Pfizer Prod Inc	Method of increasing the bioavailability and tissue penetration of azithromycin
DE10196213B4 (de) *	2000-05-19	2020-12-17	Sabinsa Corp.	Verwendung von Tetrahydropiperin zur Erhöhung der Bioverfügbarkeit von Nährstoffen und pharmazeutischen Präparationen
EP1296682A4 (en) *	2000-06-28	2004-11-10	Bakulesh Mafatlal Khamar	CHEMOSENSIZING AGENT
CZ20031262A3 (en) *	2000-10-16	2004-03-17	Neopharm, Inc.	Liposomal formulation of mitoxantrone
IT1320180B1 (it) *	2000-12-29	2003-11-26	Hunza Di Marazzita Maria Carme	Preparazioni nutrizionali e terapeutiche dotate di attivita'antiossidante ed in grado di controllare gli eccessi ponderali e
US20030068276A1 (en) *	2001-09-17	2003-04-10	Lyn Hughes	Dosage forms
DE60309582T2 (de) *	2002-04-04	2007-09-13	Cadila Pharmaceuticals Ltd.	Verfahren zur herstellung einer einen antiretroviralen proteasehemmer enthaltenden pharmazeutischen zusammensetzung mit verbesserter bioverfügbarkeit
US20070249537A1 (en) *	2003-01-23	2007-10-25	Supernus Pharmaceuticals, Inc.	Absorption enhancing agents
AU2003223111A1 (en) *	2003-03-31	2004-10-25	Council Of Scientific And Industrial Research	Use of cuminum cyminum extract and piperine for potentiation of bioefficacy of anti infectives
US20070087055A1 (en) *	2005-10-14	2007-04-19	David Jan	Directly compressible extended release alprazolam formulation
EP2011495A1 (en) *	2007-07-03	2009-01-07	Sygnis Bioscience GmbH & Co. KG	Use of piperine and derivatives thereof for the therapy of neurological conditions
US20090297622A1 (en) *	2008-01-01	2009-12-03	Khorshid Faten A	Separation and formulation of bioactive fraction and subfraction from camel urine work as anticancer agent
SI2263681T1 (sl)	2009-06-17	2015-11-30	Khorshid, Fatin A. King Abdulaziz University, Kau	Ločitev in formuliranje bioaktivne frakcije in podfrakcije iz predelave kameljega urina kot sredstva proti raku
US20140348926A1 (en)	2012-01-19	2014-11-27	Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd.	Formulation and method for increasing oral bioavailability of drugs
AT18425U1 (de)	2023-11-16	2025-03-15	Alcus Med Gmbh	Kombinationspräparat zur diätetischen behandlung von magen- und darmbeschwerden durch helicobacter pylori infektionen

1993
- 1993-10-29 IN IN356BO1993 patent/IN176897B/en unknown
1994
- 1994-10-18 US US08/324,584 patent/US5616593A/en not_active Expired - Fee Related
- 1994-10-21 AU AU75992/94A patent/AU686656B2/en not_active Ceased
- 1994-10-24 EP EP94116731A patent/EP0709098A1/en not_active Withdrawn
- 1994-10-24 ZA ZA948348A patent/ZA948348B/xx unknown
- 1994-10-28 CN CN94117602A patent/CN1121412A/zh active Pending
- 1994-10-28 CA CA002134610A patent/CA2134610A1/en not_active Abandoned

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN111246847A (zh) *	2017-08-25	2020-06-05	聪明智商股份有限公司	包含植物营养素和适应原草药的功能性咀嚼胶
CN111565721A (zh) *	2017-09-19	2020-08-21	西普拉有限公司	具有增强的生物利用度的包含依鲁替尼和生物碱的组合物

Also Published As

Publication number	Publication date
ZA948348B (en)	1995-06-14
US5616593A (en)	1997-04-01
AU7599294A (en)	1995-05-18
IN176897B (2)	1996-09-28
AU686656B2 (en)	1998-02-12
EP0709098A1 (en)	1996-05-01
CA2134610A1 (en)	1995-04-30

Legal Events

Date	Code	Title
1996-05-01	C06	Publication
1996-05-01	PB01	Publication
1996-10-16	C10	Entry into substantive examination
1996-10-16	SE01	Entry into force of request for substantive examination
2002-08-07	C02	Deemed withdrawal of patent application after publication (patent law 2001)
2002-08-07	WD01	Invention patent application deemed withdrawn after publication

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US5616593A (en)	1997-04-01	Compositions containing piperine
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JP2946452B2 (ja)	1999-09-06	ピペリンを含む組成物
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CN1121412A - 含胡椒碱的组合物 - Google Patents

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Landscapes

Priority Applications (7)

Applications Claiming Priority (2)

Publications (1)

Family

ID=37087796

Family Applications (1)

Country Status (7)

Cited By (2)

Families Citing this family (35)

Cited By (2)

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