CN1134700A - 新型紫杉化合物、其制备方法及其药物组合物 - Google Patents

新型紫杉化合物、其制备方法及其药物组合物 Download PDF

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Publication number
CN1134700A
CN1134700A CN94194073A CN94194073A CN1134700A CN 1134700 A CN1134700 A CN 1134700A CN 94194073 A CN94194073 A CN 94194073A CN 94194073 A CN94194073 A CN 94194073A CN 1134700 A CN1134700 A CN 1134700A
Authority
CN
China
Prior art keywords
group
alkyl
compound
phenyl
groups
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN94194073A
Other languages
English (en)
Chinese (zh)
Inventor
H·布查德
J·D·博尔特
A·康默克
J·P·普利加尼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Rhone Poulenc Rorer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer SA filed Critical Rhone Poulenc Rorer SA
Publication of CN1134700A publication Critical patent/CN1134700A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
CN94194073A 1993-11-08 1994-11-07 新型紫杉化合物、其制备方法及其药物组合物 Pending CN1134700A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR93/13233 1993-11-08
FR9313233A FR2712288B1 (fr) 1993-11-08 1993-11-08 Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.

Publications (1)

Publication Number Publication Date
CN1134700A true CN1134700A (zh) 1996-10-30

Family

ID=9452585

Family Applications (1)

Application Number Title Priority Date Filing Date
CN94194073A Pending CN1134700A (zh) 1993-11-08 1994-11-07 新型紫杉化合物、其制备方法及其药物组合物

Country Status (13)

Country Link
EP (1) EP0728131A1 (fr)
JP (1) JPH09504801A (fr)
CN (1) CN1134700A (fr)
AU (1) AU686690B2 (fr)
CA (1) CA2175384A1 (fr)
CZ (1) CZ133696A3 (fr)
FI (1) FI961938L (fr)
FR (1) FR2712288B1 (fr)
HU (1) HUT75063A (fr)
PL (1) PL314234A1 (fr)
SK (1) SK57496A3 (fr)
WO (1) WO1995013271A1 (fr)
ZA (1) ZA948789B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111748825A (zh) * 2019-03-28 2020-10-09 万华化学集团股份有限公司 一种成对电极反应制备ε-己内酯的方法

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2698871B1 (fr) * 1992-12-09 1995-02-24 Rhone Poulenc Rorer Sa Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
US5677470A (en) * 1994-06-28 1997-10-14 Tanabe Seiyaku Co., Ltd. Baccatin derivatives and processes for preparing the same
CA2162759A1 (fr) * 1994-11-17 1996-05-18 Kenji Tsujihara Derives de la baccatine et methodes de preparation
US5795909A (en) 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
US5919815A (en) * 1996-05-22 1999-07-06 Neuromedica, Inc. Taxane compounds and compositions
ES2151277T3 (es) * 1996-05-22 2000-12-16 Protarga Inc Composiciones que comprenden conjugados de acido cis-docosahexaenoico y taxotere.
US6495579B1 (en) 1996-12-02 2002-12-17 Angiotech Pharmaceuticals, Inc. Method for treating multiple sclerosis
US6515016B2 (en) 1996-12-02 2003-02-04 Angiotech Pharmaceuticals, Inc. Composition and methods of paclitaxel for treating psoriasis
US7235583B1 (en) 1999-03-09 2007-06-26 Luitpold Pharmaceuticals, Inc., Fatty acid-anticancer conjugates and uses thereof
EP2001874A4 (fr) * 2006-03-21 2010-04-07 Reddys Lab Ltd Dr Polymorphes de docétaxel et procédés
AU2009282413B2 (en) 2008-08-11 2014-07-17 Nektar Therapeutics Multi-arm polymeric alkanoate conjugates
WO2012088445A1 (fr) 2010-12-22 2012-06-28 Nektar Therapeutics Conjugués promédicaments polymères à plusieurs bras de composés à base de cabazitaxel
WO2012088422A1 (fr) 2010-12-22 2012-06-28 Nektar Therapeutics Conjugués promédicaments polymères à plusieurs bras de composés à base de taxane

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5254580A (en) * 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes
FR2698871B1 (fr) * 1992-12-09 1995-02-24 Rhone Poulenc Rorer Sa Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
IL107950A (en) * 1992-12-15 2001-04-30 Upjohn Co 7β, 8β - METHANO-TAXOLS, THEIR PREPARATION AND ANTINEOPLASTIC PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111748825A (zh) * 2019-03-28 2020-10-09 万华化学集团股份有限公司 一种成对电极反应制备ε-己内酯的方法

Also Published As

Publication number Publication date
FR2712288B1 (fr) 1996-01-05
HUT75063A (en) 1997-03-28
FI961938A7 (fi) 1996-05-07
HU9601219D0 (en) 1996-07-29
FI961938A0 (fi) 1996-05-07
JPH09504801A (ja) 1997-05-13
WO1995013271A1 (fr) 1995-05-18
PL314234A1 (en) 1996-09-02
CZ133696A3 (en) 1996-08-14
ZA948789B (en) 1995-07-12
FI961938L (fi) 1996-05-07
SK57496A3 (en) 1996-10-02
AU686690B2 (en) 1998-02-12
FR2712288A1 (fr) 1995-05-19
CA2175384A1 (fr) 1995-05-18
EP0728131A1 (fr) 1996-08-28
AU8147094A (en) 1995-05-29

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C01 Deemed withdrawal of patent application (patent law 1993)
WD01 Invention patent application deemed withdrawn after publication