CN1152684C - 控制释出制剂 - Google Patents

控制释出制剂 Download PDF

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Publication number
CN1152684C
CN1152684C CNB008032610A CN00803261A CN1152684C CN 1152684 C CN1152684 C CN 1152684C CN B008032610 A CNB008032610 A CN B008032610A CN 00803261 A CN00803261 A CN 00803261A CN 1152684 C CN1152684 C CN 1152684C
Authority
CN
China
Prior art keywords
alkyl
formula
group
amino
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB008032610A
Other languages
English (en)
Chinese (zh)
Other versions
CN1338935A (zh
Inventor
֮
左近圣之
楢崎雅彦
̫
藤永贤太郎
山本阳児
三桥弘明
鹤田和兴
ʷ
田边裕史
五十岚义晃
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Publication of CN1338935A publication Critical patent/CN1338935A/zh
Application granted granted Critical
Publication of CN1152684C publication Critical patent/CN1152684C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
CNB008032610A 1999-01-28 2000-01-25 控制释出制剂 Expired - Fee Related CN1152684C (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP19815/1999 1999-01-28
JP1981599 1999-01-28
JP19815/99 1999-01-28

Publications (2)

Publication Number Publication Date
CN1338935A CN1338935A (zh) 2002-03-06
CN1152684C true CN1152684C (zh) 2004-06-09

Family

ID=12009831

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB008032610A Expired - Fee Related CN1152684C (zh) 1999-01-28 2000-01-25 控制释出制剂

Country Status (10)

Country Link
US (1) US6676968B1 (fr)
EP (1) EP1179344B1 (fr)
KR (1) KR20010101772A (fr)
CN (1) CN1152684C (fr)
AT (1) ATE339204T1 (fr)
AU (1) AU773156B2 (fr)
CA (1) CA2360686A1 (fr)
DE (1) DE60030710D1 (fr)
TW (1) TW592699B (fr)
WO (1) WO2000044380A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030076634A (ko) * 2001-01-30 2003-09-26 데이진 가부시키가이샤 의약 조성물
AR035425A1 (es) * 2001-01-30 2004-05-26 Teijin Ltd Cristal de diclorhidrato del acido 3-(3-amidinofenil)-5-[({[1-(iminoetil)-4-piperidil]metil}amino)metil]benzoico y proceso para prepararlo
CN117467423B (zh) * 2023-12-28 2024-03-05 成都华阳兴华化工有限公司 耐高温泡沫驱油剂

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4102024A1 (de) * 1991-01-24 1992-07-30 Thomae Gmbh Dr K Biphenylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
ATE140225T1 (de) * 1992-04-28 1996-07-15 Thomae Gmbh Dr K Tritiumarkierte fibrinogen-rezeptor-antagonisten, deren verwendung und verfahren zur ihrer herstellung
JPH092977A (ja) 1995-06-21 1997-01-07 Dai Ichi Seiyaku Co Ltd 経口投与用医薬組成物
JPH101467A (ja) 1996-06-13 1998-01-06 Banyu Pharmaceut Co Ltd ビフェニルアミジン誘導体
BR9710383A (pt) * 1996-07-23 1999-08-17 Daiichi Seiyaku Co Intensificador de absor-Æo
JPH10231254A (ja) * 1996-12-19 1998-09-02 Dai Ichi Seiyaku Co Ltd 経口吸収改善医薬用組成物
DK1043310T3 (da) * 1997-11-20 2004-10-25 Teijin Ltd Biphenylamidinderivater
JPH11152269A (ja) * 1997-11-20 1999-06-08 Teijin Ltd ビフェニルアミジン誘導体
NZ504324A (en) * 1997-11-20 2002-02-01 Teijin Ltd Biphenylamidine derivatives and pharmaceutical compositions thereof; which can be useful as anticoagulant inhibitors, and thrombus or embolus preventing agents
US5886239A (en) * 1997-11-21 1999-03-23 Baxter International Inc. Method of preparing monofluoromethyl ethers
DE19819548A1 (de) * 1998-04-30 1999-11-04 Merck Patent Gmbh Biphenylderivate
JP2000178243A (ja) * 1998-12-14 2000-06-27 Teijin Ltd ビフェニルアミジン誘導体

Also Published As

Publication number Publication date
ATE339204T1 (de) 2006-10-15
AU3078300A (en) 2000-08-18
KR20010101772A (ko) 2001-11-14
CA2360686A1 (fr) 2000-08-03
US6676968B1 (en) 2004-01-13
CN1338935A (zh) 2002-03-06
AU773156B2 (en) 2004-05-20
EP1179344B1 (fr) 2006-09-13
EP1179344A1 (fr) 2002-02-13
EP1179344A4 (fr) 2004-05-06
DE60030710D1 (de) 2006-10-26
WO2000044380A1 (fr) 2000-08-03
TW592699B (en) 2004-06-21

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GR01 Patent grant
C19 Lapse of patent right due to non-payment of the annual fee
CF01 Termination of patent right due to non-payment of annual fee