CN120289727A - A scented UV light-curing contact lens material and its preparation method and application - Google Patents
A scented UV light-curing contact lens material and its preparation method and application Download PDFInfo
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Abstract
The invention belongs to the technical field of contact lenses, and particularly discloses a UV (ultraviolet) photocuring contact lens material with fragrance, and a preparation method and application thereof. The contact lens material disclosed by the invention is prepared from 30-40 parts of siloxane monomer, 50-80 parts of hydrophilic monomer, 0.01-0.1 part of nanocapsule, 0.5-1.5 parts of cross-linking agent, 0.2-0.8 part of ultraviolet absorber and 0.5-1.5 parts of initiator. Wherein the core material of the nanocapsule comprises alpha-bisabolol, vanillin and apigenin. The active component can relieve xerophthalmia, ocular inflammation and ocular dryness, and avoid a plurality of problems caused by wearing contact lenses to a certain extent; the invention also discloses application of the nanocapsule, realizes slow release of the effective components, avoids stimulation to eyes, and has the effect of permanently emitting fragrance and making a wearer feel happy.
Description
Technical Field
The invention relates to the technical field of contact lenses, in particular to a UV (ultraviolet) light curing contact lens material with fragrance, and a preparation method and application thereof.
Background
Contact lenses have undergone many technological innovations since the mid-20 th century as an important tool for modern vision correction. From the original hard lenses to the soft hydrogel, silicone hydrogel materials of today, contact lenses have made significant advances in comfort, oxygen permeability, and wear duration. In particular, silicone hydrogel contact lenses, which have the characteristics of ultra-high oxygen permeability and high moisture content, can reduce dry eye discomfort, can achieve comfortable wear for more than 12 hours, and have become a mainstream choice for the modern contact lens market by virtue of their unique advantages.
However, as consumer demand for personalized, multifunctional products increases, conventional contact lenses have not fully met market expectations. In recent years, innovative products such as intelligent contact lenses, drug-release contact lenses and the like are sequentially developed, and the great potential in the field is shown. Under the background, the UV light curing contact lens with fragrance is used as a novel product which integrates sensory experience and advanced material technology, and has important research value and application prospect.
With the widespread use of silicone hydrogel contact lenses, a significant extension of the comfortable wear time (even the appearance of products that can be worn for 7 days in succession) creates the potential for the development of fragrance release functionality for contact lenses. How to perfectly combine the fragrance molecules with the contact lens matrix, and ensure the stability and safety of fragrance release on the premise of not affecting the oxygen permeability and optical performance of the lens, and enrich the functions of the contact lens, thereby becoming the primary problem.
Therefore, how to provide a UV light-cured contact lens material with fragrance, a preparation method and application thereof, and to blend fragrance functional molecules into the contact lens material under the premise of ensuring safety, so that the contact lens material has the function of slowly releasing fragrance is a problem to be solved in the field.
Disclosure of Invention
In view of the above, the invention provides a UV light curing contact lens material with fragrance, a preparation method and application thereof, and solves the problems that the existing contact lens material has single function and does not have the function of slowly releasing fragrance.
In order to achieve the above purpose, the invention adopts the following technical scheme:
The UV light-cured contact lens material with fragrance is prepared from the following raw materials in parts by weight:
30-40 parts of siloxane monomer, 50-80 parts of hydrophilic monomer, 0.01-0.1 part of nanocapsule, 0.5-1.5 parts of cross-linking agent, 0.2-0.8 part of ultraviolet absorber and 0.5-1.5 parts of initiator;
the nanocapsule comprises a wall material and a core material, wherein the core material of the nanocapsule comprises alpha-bisabolol, vanillin and apigenin.
Preferably, the preparation method of the nanocapsule comprises the following steps:
1) Dissolving beta-cyclodextrin in water to obtain beta-cyclodextrin aqueous solution;
dissolving alpha-bisabolol, vanillin and apigenin in ethanol to obtain a mixed solution;
2) Adding the mixed solution into beta-cyclodextrin water solution, clathrating to obtain clathrate solution, 3) homogenizing the clathrate solution under high pressure, and spray drying to obtain nanocapsule. Preferably, the mass concentration of the beta-cyclodextrin in the beta-cyclodextrin aqueous solution is 60-80 g/L;
The molar ratio of the total mol of the alpha-bisabolol, the vanillin and the apigenin to the beta-cyclodextrin is 0.7-1:1;
the molar ratio of the alpha-bisabolol to the vanillin to the apigenin is 1-5:0.3-0.5:2-5;
The volume ratio of the mixed solution to the beta-cyclodextrin aqueous solution is 1-5:10.
Preferably, the time of the inclusion reaction in the step 2) is 1-2 hours, and the temperature of the inclusion reaction is 50-60 ℃.
Preferably, the high-pressure homogenizing pressure is 20-50 MPa, the high-pressure homogenizing temperature is 25-40 ℃, and the times of high-pressure homogenizing are 2-3 times;
The spray drying temperature is <80 ℃;
The particle size of the nanocapsules is 20-250 nm.
Preferably, the siloxane monomer comprises one or more of methacryloxypropyl tris (trimethylsiloxy) silane, terminal divinyl polydimethylsiloxane, 1, 3-bis (3-methacryloxypropyl) tetrakis (trimethylsiloxy) disiloxane, and N- (3-methacryloxy-2-hydroxypropyl) -3-aminopropyl triethoxysilane.
Preferably, the hydrophilic monomer comprises one or more of N-vinyl pyrrolidone, hydroxyethyl methacrylate, butyl methacrylate, methacrylic acid, dimethylaminoethyl methacrylate and glycerol methacrylate.
Preferably, the cross-linking agent comprises one or more of ethylene glycol dimethacrylate, tetraethylene glycol dimethacrylate and trimethylolpropane trimethacrylate;
The ultraviolet absorber comprises benzotriazole ultraviolet absorber and/or triazine ultraviolet absorber;
the initiator comprises one or more of bis (2, 4, 6-trimethylbenzoyl) phenylphosphine oxide, 2,4, 6-trimethylbenzoyl-diphenylphosphine oxide and 2-hydroxy-4' - (2-hydroxyethoxy) -2-methylbenzophenone.
The invention further provides a preparation method of the UV light-cured contact lens material with fragrance, which comprises the following steps of mixing a siloxane monomer, a hydrophilic monomer, a nano-capsule, a cross-linking agent, an ultraviolet absorbent and an initiator, and then sequentially performing mold injection molding, UV light curing, soaking and sterilization to obtain the UV light-cured contact lens material with fragrance.
The invention also aims to provide an application of the fragrant UV light curing contact lens material prepared by the preparation method in preparation of contact lenses.
Compared with the prior art, the invention has the following beneficial effects:
1. The contact lens material prepared by the invention is a silicon hydrogel contact lens material, has good comfortable wearing property and can be worn for a long time. The invention also adds nanocapsules on the basis of the silicon hydrogel contact lens material, wherein the nanocapsules are coated with alpha-bisabolol, vanillin and apigenin, the alpha-bisabolol is a main active ingredient of chamomile, has the effects of relieving eye inflammation or eye dryness caused by long-time wearing, the vanillin can release aroma, the apigenin is a natural flavonoid compound, phenolic hydroxyl and double bonds in a molecular structure enable the apigenin to have antioxidant and anti-inflammatory properties, and the activity of the apigenin can be enhanced by the cooperation of the alpha-bisabolol.
2. The invention adopts the form of nano-capsule coating to add alpha-bisabolol, vanillin and apigenin, thereby realizing the slow release of the effective components and avoiding the irritation to eyes. Toxicology-related tests show that the silicon hydrogel contact lens material prepared by the invention has no stimulation and good biocompatibility.
3. The silicon hydrogel contact lens material prepared by the invention can permanently emit fragrance, so that a wearer can feel happy and uncomfortable feeling caused by wearing the contact lens for a long time can be relieved.
Detailed Description
The invention provides a fragrant UV light curing contact lens material which is prepared from the following raw materials in parts by weight:
30-40 parts of siloxane monomer, 50-80 parts of hydrophilic monomer, 0.01-0.1 part of nano-capsule, 0.5-1.5 part of cross-linking agent, 0.2-0.8 part of ultraviolet absorber and 0.5-1.5 part of initiator, wherein the addition amount of the siloxane monomer can be 3234353638 parts by mass, the addition amount of the hydrophilic monomer can be 52 parts, 55 parts, 58 parts, 60 parts, 62 parts, 65 parts, 68 parts, 70 parts, 72 parts, 75 parts and 78 parts by mass, the addition amount of the nano-capsule can be 0.01 parts, 0.02 parts, 0.04 parts, 0.05 parts, 0.06 parts, 0.08 parts and 0.09 parts, the addition amount of the cross-linking agent can be 0.6 parts, 0.8 parts, 1 part, 1.2 parts and 1.4 parts by mass, and the addition amount of the ultraviolet absorber can be 0.3 parts, 0.4 parts, 0.5 parts, 0.6 parts, 0.7 parts, 0.04 parts and 1.8 parts by mass, and 1.4 parts by mass.
In the invention, the nanocapsule comprises a wall material and a core material, and the core material of the nanocapsule comprises alpha-bisabolol, vanillin and apigenin.
In the invention, the preparation method of the nanocapsule comprises the following steps:
1) Dissolving beta-cyclodextrin in water to obtain beta-cyclodextrin aqueous solution;
dissolving alpha-bisabolol, vanillin and apigenin in ethanol to obtain a mixed solution;
2) Adding the mixed solution into beta-cyclodextrin water solution, clathrating to obtain clathrate solution, 3) homogenizing the clathrate solution under high pressure, and spray drying to obtain nanocapsule.
In the invention, the beta-cyclodextrin is a biodegradable material, and the beta-cyclodextrin is adopted as a wall material of the nanocapsule to realize the slow release of the effective components.
In the invention, the mass concentration of the beta-cyclodextrin in the beta-cyclodextrin aqueous solution is 60-80 g/L, and specifically can be 62g/L, 64g/L, 65g/L, 66g/L, 68g/L, 70g/L, 72g/L, 74g/L, 75g/L, 76g/L and 78g/L.
In the invention, the molar ratio of the total mole of the alpha-bisabolol, the vanillin and the apigenin to the beta-cyclodextrin is 0.7-1:1, preferably 0.8-0.9:1, and more preferably 0.85:1.
In the invention, the molar ratio of the alpha-bisabolol to the vanillin to the apigenin is 1-5:0.3-0.5:2-5, preferably 2-4:0.35-0.45:3-4, and more preferably 3:0.4:3.5.
In the invention, the volume ratio of the mixed solution to the beta-cyclodextrin aqueous solution is 1-5:10, preferably 2-4:10, and more preferably 3:10.
In the invention, the time of the inclusion reaction in the step 2) is 1-2 h, specifically 1.2h, 1.4h, 1.5h, 1.6h and 1.8h, and the temperature of the inclusion reaction is 50-60 ℃ and specifically 52 ℃, 54 ℃, 55 ℃,56 ℃ and 58 ℃.
The high-pressure homogenizing pressure is 20-50 MPa, specifically 25-40 MPa, specifically 26-28 ℃,30 ℃, 32 ℃, 34 ℃, 35 ℃, 36 ℃ and 38 ℃ and the times of high-pressure homogenizing are 2-3 times;
in the present invention, the spray drying temperature is <80 ℃, and may be specifically 50 ℃, 55 ℃, 60 ℃, 65 ℃, 70 ℃ or 75 ℃.
In the invention, the particle size of the nanocapsule is 20-250 nm, and specifically can be 40nm, 50nm, 60nm, 80nm, 100nm, 120nm, 150nm, 160nm, 180nm, 200nm, 220nm and 240nm.
The UV light curing contact lens material has small particle size of the nanocapsules, and the coating material is colorless and transparent, so that the optical performance of the contact lens is not affected.
In the present invention, the siloxane monomer includes one or more of methacryloxypropyl tris (trimethylsiloxy) silane, terminal divinyl polydimethylsiloxane, 1, 3-bis (3-methacryloxypropyl) tetrakis (trimethylsiloxy) disiloxane, and N- (3-methacryloxy2-hydroxypropyl) -3-aminopropyl triethoxysilane.
In the present invention, the hydrophilic monomer includes one or more of N-vinylpyrrolidone, hydroxyethyl methacrylate, butyl methacrylate, methacrylic acid, dimethylaminoethyl methacrylate and glycerol methacrylate.
In the present invention, the crosslinking agent includes one or more of ethylene glycol dimethacrylate, tetraethylene glycol dimethacrylate and trimethylolpropane trimethacrylate.
In the present invention, the ultraviolet absorber includes benzotriazole-based ultraviolet absorbers and/or triazine-based ultraviolet absorbers.
In the present invention, the initiator includes one or more of bis (2, 4, 6-trimethylbenzoyl) phenylphosphine oxide, 2,4, 6-trimethylbenzoyl-diphenylphosphine oxide, and 2-hydroxy-4' - (2-hydroxyethoxy) -2-methylpropionne.
The invention also provides a preparation method of the UV light-cured contact lens material with fragrance, which comprises the following steps of mixing a siloxane monomer, a hydrophilic monomer, a nano capsule, a cross-linking agent, an ultraviolet absorber and an initiator, and then sequentially performing mold injection molding, UV light curing, soaking and sterilization to obtain the UV light-cured contact lens material with fragrance.
The invention also provides an application of the fragrant UV light curing contact lens material prepared by the preparation method in preparation of contact lenses.
The following description of the technical solutions in the embodiments of the present invention will be clear and complete, and it is obvious that the described embodiments are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Example 1
Dissolving beta-cyclodextrin in water (60 ℃) to obtain beta-cyclodextrin water solution, and dissolving alpha-bisabolol, vanillin and apigenin with the molar ratio of 2:0.3:3 in ethanol to obtain mixed alcohol solution. Then, the mixed alcohol solution was added dropwise to an aqueous beta-cyclodextrin solution (mixed alcohol solution: aqueous beta-cyclodextrin solution=2:10, mass concentration of the aqueous beta-cyclodextrin solution was 65g/L, molar ratio of total mole of alpha-bisabolol, vanillin and apigenin to beta-cyclodextrin was 0.8:1), temperature was adjusted to 60 ℃, and stirring was carried out for 1.5 hours, to obtain a clathrate solution. Then the inclusion compound solution is homogenized under high pressure at 20MPa and 30 ℃ and then homogenized under high pressure at 30MPa and 30 ℃. And after high-pressure homogenization is finished, spray drying is carried out at 70 ℃ to obtain the nano-capsule coated with alpha-bisabolol, vanillin and apigenin, wherein the particle size of the nano-capsule is 50-150 nm, and the loading capacity of the nano-capsule is 10.5%.
35 Parts of terminal divinyl polydimethylsiloxane, 70 parts of N-vinyl pyrrolidone, 0.05 part of nanocapsule, 0.8 part of ethylene glycol dimethacrylate, 0.3 part of 2- (2' -hydroxy-5-methacryloyloxyethyl phenyl) -2H-benzotriazole and 1 part of 2,4, 6-trimethyl benzoyl-diphenyl phosphine oxide are mixed to obtain a contact lens material mixed solution, then the contact lens material mixed solution is injected into a mold, ultraviolet light curing molding is carried out, and soaking and sterilization are sequentially carried out after curing, so that the UV light curing contact lens material with fragrance is obtained.
Example 2
Dissolving beta-cyclodextrin in water (60 ℃) to obtain beta-cyclodextrin water solution, and dissolving alpha-bisabolol, vanillin and apigenin with a molar ratio of 5:0.5:5 in ethanol to obtain mixed alcohol solution. Then, the mixed alcohol solution was dropwise added to the aqueous beta-cyclodextrin solution (mixed alcohol solution: aqueous beta-cyclodextrin solution=3:10, mass concentration of the aqueous beta-cyclodextrin solution is 60g/L, molar ratio of total mole of alpha-bisabolol, vanillin and apigenin to beta-cyclodextrin is 0.8:1), temperature was adjusted to 60 ℃, and stirring was carried out for 2 hours, to obtain clathrate solution. The clathrate solution was then homogenized three times under high pressure at 30mpa and 30 ℃. And after high-pressure homogenization is finished, spray drying is carried out at 60 ℃ to obtain the nano-capsule coated with alpha-bisabolol, vanillin and apigenin, wherein the particle size of the nano-capsule is 20-120 nm, and the loading capacity of the nano-capsule is 9.8%.
30 Parts of terminal divinyl polydimethylsiloxane, 58 parts of N-vinyl pyrrolidone, 0.01 part of nanocapsule, 0.6 part of tetraethylene glycol dimethacrylate, 0.3 part of 2- (2' -hydroxy-5-methacryloyloxyethyl phenyl) -2H-benzotriazole and 0.5 part of bis (2, 4, 6-trimethylbenzoyl) phenyl phosphine oxide are mixed to obtain a contact lens material mixed solution, then the contact lens material mixed solution is injected into a mold, ultraviolet curing molding is carried out, and soaking and sterilization are sequentially carried out after curing, so that the UV light curing contact lens material with fragrance is obtained.
Example 3
Dissolving beta-cyclodextrin in water (50 ℃) to obtain beta-cyclodextrin water solution, and dissolving alpha-bisabolol, vanillin and apigenin with a molar ratio of 3:0.4:4 in ethanol to obtain mixed alcohol solution. Then, the mixed alcohol solution was dropwise added to the aqueous beta-cyclodextrin solution (mixed alcohol solution: aqueous beta-cyclodextrin solution=1:10, mass concentration of the aqueous beta-cyclodextrin solution is 70g/L, molar ratio of total mole of alpha-bisabolol, vanillin and apigenin to beta-cyclodextrin is 0.8:1), temperature was adjusted to 50 ℃, and stirring was carried out for 2 hours, to obtain clathrate solution. Then the clathrate solution was homogenized twice under high pressure at 20MPa and 30 ℃ and then under high pressure at 30MPa and 30 ℃. And after high-pressure homogenization is finished, spray drying is carried out at 70 ℃ to obtain the nano-capsule coated with alpha-bisabolol, vanillin and apigenin, wherein the particle size of the nano-capsule is 20-100 nm, and the loading capacity of the nano-capsule is 9.5%.
40 Parts of methacryloxypropyl tris (trimethylsiloxy) silane, 75 parts of hydroxyethyl methacrylate, 0.08 part of nanocapsule, 1.2 parts of ethylene glycol dimethacrylate, 0.8 part of 2- (2' -hydroxy-5-methacryloxyethylphenyl) -2H-benzotriazole and 1.5 parts of 2,4, 6-trimethylbenzoyl-diphenyl phosphine oxide are mixed to obtain a contact lens material mixed solution, then the contact lens material mixed solution is injected into a mold, ultraviolet curing molding is carried out, and soaking and sterilization are sequentially carried out after curing, so that the UV light curing contact lens material with fragrance is obtained.
Example 4
Dissolving beta-cyclodextrin in water (60 ℃) to obtain beta-cyclodextrin water solution, and dissolving alpha-bisabolol, vanillin and apigenin with the molar ratio of 1:0.3:2 in ethanol to obtain mixed alcohol solution. Then, the mixed alcohol solution was added dropwise to an aqueous beta-cyclodextrin solution (mixed alcohol solution: aqueous beta-cyclodextrin solution=1:10, mass concentration of aqueous beta-cyclodextrin solution is 80g/L, molar ratio of total mole of alpha-bisabolol, vanillin and apigenin to beta-cyclodextrin is 1:1), temperature was adjusted to 60 ℃, and stirring was carried out for 1h, to obtain clathrate solution. Then the clathrate solution was homogenized under high pressure at 25MPa and 25 ℃ and then at 40MPa and 25 ℃. And after high-pressure homogenization is finished, spray drying is carried out at 75 ℃ to obtain the nano-capsule coated with alpha-bisabolol, vanillin and apigenin, wherein the particle size of the nano-capsule is 100-200 nm, and the loading capacity of the nano-capsule is 10.2%.
36 Parts of terminal divinyl polydimethylsiloxane, 70 parts of N-vinyl pyrrolidone, 0.03 part of nanocapsule, 0.6 part of ethylene glycol dimethacrylate, 0.5 part of 2- (2' -hydroxy-5-methacryloyloxyethyl phenyl) -2H-benzotriazole and 1.2 parts of 2,4, 6-trimethyl benzoyl-diphenyl phosphine oxide are mixed to obtain a contact lens material mixed solution, then the contact lens material mixed solution is injected into a mold, ultraviolet curing molding is carried out, and soaking and sterilization are sequentially carried out after curing, so that the UV light curing contact lens material with fragrance is obtained.
Experimental example 1
The fragrant UV light-cured contact lens materials prepared in examples 1-4 were tested as follows:
the cytotoxicity test is according to the standard ISO9363-1 (the test result is classified into 0-4 grade, the lower the value is, the better the material safety is proved);
Moisture content test hydrogel contact lens moisture content/evaporation loss was measured according to the "gravimetric method" described in the 4.5 moisture content section of GB/T11417.7-2012;
Oxygen permeation test is based on the standard of 4.4.3 polarography in GB/T11417.7-2012;
The light transmittance test is based on the test method described in the 4.4 refractive index part of GB/T11417.7-2012;
The contact angle test was carried out according to the test method described in the section 4.6 contact angle of GB/T11417.7-2012, and the test results are shown in Table 1.
Table 1 test results
The cytotoxicity of the UV light-cured contact lens material with the fragrance prepared by the invention is 0 grade, the material safety is good, the added alpha-bisabolol, vanillin and apigenin components cannot cause stimulation to human bodies, the safety is high, in addition, the parameters of the contact lens material such as the water content, the oxygen permeability and the like are excellent, the requirement of wearing comfort for a long time can be met, the effects of relieving xerophthalmia, ocular inflammation and the like can be achieved based on the addition of the effective components, the fragrance can be slowly released by the contact lens material in the wearing process for a long time, the fragrance is mild and not stimulated, and a wearer can feel physical and mental pleasure.
In the present specification, each embodiment is described in a progressive manner, and each embodiment is mainly described in a different point from other embodiments, and identical and similar parts between the embodiments are all enough to refer to each other.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (10)
1. The fragrant UV light-cured contact lens material is characterized by being prepared from the following raw materials in parts by weight:
30-40 parts of siloxane monomer, 50-80 parts of hydrophilic monomer, 0.01-0.1 part of nanocapsule, 0.5-1.5 parts of cross-linking agent, 0.2-0.8 part of ultraviolet absorber and 0.5-1.5 parts of initiator;
the nanocapsule comprises a wall material and a core material, wherein the core material of the nanocapsule comprises alpha-bisabolol, vanillin and apigenin.
2. A flavored UV light curable contact lens material in accordance with claim 1, wherein said nanocapsule is prepared by a process comprising the steps of:
1) Dissolving beta-cyclodextrin in water to obtain beta-cyclodextrin aqueous solution;
dissolving alpha-bisabolol, vanillin and apigenin in ethanol to obtain a mixed solution;
2) Dripping the mixed solution into beta-cyclodextrin aqueous solution, and carrying out inclusion reaction to obtain inclusion compound solution;
3) Homogenizing the clathrate solution under high pressure, and spray drying to obtain nanocapsule.
3. The fragrant UV light-curable contact lens material of claim 2, wherein the mass concentration of beta-cyclodextrin in the beta-cyclodextrin aqueous solution is 60-80 g/L;
The molar ratio of the total mol of the alpha-bisabolol, the vanillin and the apigenin to the beta-cyclodextrin is 0.7-1:1;
the molar ratio of the alpha-bisabolol to the vanillin to the apigenin is 1-5:0.3-0.5:2-5;
The volume ratio of the mixed solution to the beta-cyclodextrin aqueous solution is 1-5:10.
4. A perfumed UV light curable contact lens material according to claim 2 or 3, wherein the inclusion reaction time in step 2) is 1-2 hours and the inclusion reaction temperature is 50-60 ℃.
5. The flavored UV light curable contact lens material according to claim 4, wherein the high pressure homogenizing pressure is 20-50 mpa, the high pressure homogenizing temperature is 25-40 ℃, and the number of times of high pressure homogenizing is 2-3 times;
the spray drying temperature is <80 ℃;
The particle size of the nanocapsules is 20-250 nm.
6. The fragrant UV light curable contact lens material of any one of claims 1-3, 5, wherein said siloxane monomers comprise one or more of methacryloxypropyl tris (trimethylsiloxy) silane, terminal divinyl polydimethylsiloxane, 1, 3-bis (3-methacryloxypropyl) tetrakis (trimethylsiloxy) disiloxane, and N- (3-methacryloxy2-hydroxypropyl) -3-aminopropyl triethoxysilane.
7. A flavored UV light curable contact lens material in accordance with claim 6, wherein the hydrophilic monomer comprises one or more of N-vinyl pyrrolidone, hydroxyethyl methacrylate, butyl methacrylate, methacrylic acid, dimethylaminoethyl methacrylate, and glyceryl methacrylate.
8. A flavored UV light curable contact lens material in accordance with claim 7, wherein said crosslinking agent comprises one or more of ethylene glycol dimethacrylate, tetraethylene glycol dimethacrylate and trimethylolpropane trimethacrylate;
The ultraviolet absorber comprises benzotriazole ultraviolet absorber and/or triazine ultraviolet absorber;
the initiator comprises one or more of bis (2, 4, 6-trimethylbenzoyl) phenylphosphine oxide, 2,4, 6-trimethylbenzoyl-diphenylphosphine oxide and 2-hydroxy-4' - (2-hydroxyethoxy) -2-methylbenzophenone.
9. The method for preparing the fragrant UV light-cured contact lens material according to any one of claims 1-8, which is characterized by comprising the steps of mixing a siloxane monomer, a hydrophilic monomer, a nanocapsule, a cross-linking agent, an ultraviolet absorber and an initiator, and then sequentially performing mold injection, UV light curing, soaking and sterilization to obtain the fragrant UV light-cured contact lens material.
10. Use of a flavored UV light curable contact lens material prepared by the method of claim 9 in the preparation of a contact lens.
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| CN202510600293.5A CN120289727A (en) | 2025-05-12 | 2025-05-12 | A scented UV light-curing contact lens material and its preparation method and application |
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| CN202510600293.5A CN120289727A (en) | 2025-05-12 | 2025-05-12 | A scented UV light-curing contact lens material and its preparation method and application |
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- 2025-05-12 CN CN202510600293.5A patent/CN120289727A/en active Pending
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