CN1205917C - Human lysozyme series cosmetics and its preparation method - Google Patents
Human lysozyme series cosmetics and its preparation method Download PDFInfo
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- CN1205917C CN1205917C CN 02132412 CN02132412A CN1205917C CN 1205917 C CN1205917 C CN 1205917C CN 02132412 CN02132412 CN 02132412 CN 02132412 A CN02132412 A CN 02132412A CN 1205917 C CN1205917 C CN 1205917C
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- human lysozyme
- cosmetics
- essence
- lysozyme
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- 101001018100 Homo sapiens Lysozyme C Proteins 0.000 title claims abstract description 63
- 239000002537 cosmetic Substances 0.000 title claims abstract description 27
- 238000002360 preparation method Methods 0.000 title claims abstract description 9
- 239000002994 raw material Substances 0.000 claims abstract description 24
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 48
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 20
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 19
- 238000003756 stirring Methods 0.000 claims description 16
- 239000008367 deionised water Substances 0.000 claims description 12
- 229910021641 deionized water Inorganic materials 0.000 claims description 12
- 229930003427 Vitamin E Natural products 0.000 claims description 10
- 238000005516 engineering process Methods 0.000 claims description 10
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 10
- 239000000243 solution Substances 0.000 claims description 10
- 239000011709 vitamin E Substances 0.000 claims description 10
- 235000019165 vitamin E Nutrition 0.000 claims description 10
- 229940046009 vitamin E Drugs 0.000 claims description 10
- 239000003921 oil Substances 0.000 claims description 9
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 8
- 239000002562 thickening agent Substances 0.000 claims description 8
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims description 7
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 7
- 229920002674 hyaluronan Polymers 0.000 claims description 7
- 229960003160 hyaluronic acid Drugs 0.000 claims description 7
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 6
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims description 6
- 229920002125 Sokalan® Polymers 0.000 claims description 6
- 239000002253 acid Substances 0.000 claims description 6
- 229960001631 carbomer Drugs 0.000 claims description 6
- 239000003995 emulsifying agent Substances 0.000 claims description 6
- 230000001804 emulsifying effect Effects 0.000 claims description 6
- 235000010335 lysozyme Nutrition 0.000 claims description 6
- 229910052710 silicon Inorganic materials 0.000 claims description 6
- 239000010703 silicon Substances 0.000 claims description 6
- 108010014251 Muramidase Proteins 0.000 claims description 5
- 102000016943 Muramidase Human genes 0.000 claims description 5
- 108010062010 N-Acetylmuramoyl-L-alanine Amidase Proteins 0.000 claims description 5
- 239000004359 castor oil Substances 0.000 claims description 5
- 235000019438 castor oil Nutrition 0.000 claims description 5
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 claims description 5
- 239000004325 lysozyme Substances 0.000 claims description 5
- 229960000274 lysozyme Drugs 0.000 claims description 5
- 239000012467 final product Substances 0.000 claims description 4
- 239000000203 mixture Substances 0.000 claims description 4
- 239000000047 product Substances 0.000 claims description 4
- SCPYDCQAZCOKTP-UHFFFAOYSA-N silanol Chemical compound [SiH3]O SCPYDCQAZCOKTP-UHFFFAOYSA-N 0.000 claims description 4
- 230000002087 whitening effect Effects 0.000 claims description 4
- AXTGDCSMTYGJND-UHFFFAOYSA-N 1-dodecylazepan-2-one Chemical compound CCCCCCCCCCCCN1CCCCCC1=O AXTGDCSMTYGJND-UHFFFAOYSA-N 0.000 claims description 3
- AMUTYVGRCVFCCD-UHFFFAOYSA-N 5,6-diaminopyridine-3-carboxylic acid Chemical compound NC1=CC(C(O)=O)=CN=C1N AMUTYVGRCVFCCD-UHFFFAOYSA-N 0.000 claims description 3
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 claims description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 3
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims description 3
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 3
- 229910052799 carbon Inorganic materials 0.000 claims description 3
- 229940008099 dimethicone Drugs 0.000 claims description 3
- 239000004205 dimethyl polysiloxane Substances 0.000 claims description 3
- 235000013870 dimethyl polysiloxane Nutrition 0.000 claims description 3
- 239000004519 grease Substances 0.000 claims description 3
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims description 3
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims description 3
- 229920001296 polysiloxane Polymers 0.000 claims description 3
- 229920000053 polysorbate 80 Polymers 0.000 claims description 3
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 3
- 235000002917 Fraxinus ornus Nutrition 0.000 claims description 2
- 239000004909 Moisturizer Substances 0.000 claims description 2
- 150000001412 amines Chemical class 0.000 claims description 2
- 239000007864 aqueous solution Substances 0.000 claims description 2
- 238000005282 brightening Methods 0.000 claims description 2
- 239000007970 homogeneous dispersion Substances 0.000 claims description 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 2
- 230000001333 moisturizer Effects 0.000 claims description 2
- 229920001223 polyethylene glycol Polymers 0.000 claims description 2
- 150000005846 sugar alcohols Chemical class 0.000 claims description 2
- 239000003643 water by type Substances 0.000 claims 2
- 244000182067 Fraxinus ornus Species 0.000 claims 1
- 235000010627 Phaseolus vulgaris Nutrition 0.000 claims 1
- 244000046052 Phaseolus vulgaris Species 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 abstract description 8
- 230000000694 effects Effects 0.000 abstract description 3
- 238000000034 method Methods 0.000 abstract description 3
- 239000000470 constituent Substances 0.000 abstract 1
- 238000000265 homogenisation Methods 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- 238000007664 blowing Methods 0.000 description 4
- 238000007599 discharging Methods 0.000 description 3
- 238000010438 heat treatment Methods 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 241000287828 Gallus gallus Species 0.000 description 2
- -1 polyethylene Polymers 0.000 description 2
- JVTIXNMXDLQEJE-UHFFFAOYSA-N 2-decanoyloxypropyl decanoate 2-octanoyloxypropyl octanoate Chemical compound C(CCCCCCC)(=O)OCC(C)OC(CCCCCCC)=O.C(=O)(CCCCCCCCC)OCC(C)OC(=O)CCCCCCCCC JVTIXNMXDLQEJE-UHFFFAOYSA-N 0.000 description 1
- 241001289435 Astragalus brachycalyx Species 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000013064 chemical raw material Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 239000000498 cooling water Substances 0.000 description 1
- 238000007872 degassing Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000009849 vacuum degassing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The present invention relates to a series of cosmetics and a preparation method thereof, particularly to a series of human lysozyme cosmetics and a preparation method thereof. The major constituent of the series of human lysozyme cosmetics is human lysozyme (HLZ), and the technological processes are as follows: human lysozyme is firstly prepared for spare use, raw materials are agitated and cooled to 45 DEG C after homogeneously emulsified, and then, the prepared human lysozyme is degassed and agitated to a certain temperature in vacuum after poured into the raw materials. The present invention has the advantages of easy raw material source, simple manufacturing process, obvious effect and convenient application.
Description
Technical field:
The present invention relates to a kind of cosmetics and preparation method thereof, particularly relate to a kind of human lysozyme series cosmetics and preparation method thereof.
Background technology:
Present widely used cosmetics are the synthetic or adding plant component formation with chemical raw material mostly; As cleawhite pack, QUBAN SHUANG and astringent etc.Japan produces cosmetics with lysozyme of chicken, and lysozyme of chicken is that foreign protein has irritated reflection to human body skin.
Summary of the invention:
The invention provides a kind of human lysozyme series cosmetics and preparation method thereof, because human lysozyme is gene engineering product, gene source is in human body, so, for human body irritated reflection does not take place, and human body cell is had repair.And cost is low, and production technology is simple, and effect is remarkable.
Technical scheme of the present invention is: the main component of human lysozyme series skin nursing products is human lysozyme Human lysozyme (HLZ), the active unit that contains human lysozyme in its every gram cosmetics is 150U-600 ten thousand U, the content of human lysozyme is 0.018-200mg, and purity is 85%-99.52%.Its technical process is as follows: at first the pure product of human lysozyme are added make in 15% the water behind the human lysozyme aqueous solution standby, to stir behind the various raw material homogeneous dispersions again, emulsifying postcooling to 45 degree, adding outgases to uniform temperature through stirring vacuum with the human lysozyme for preparing gets final product.
Good effect of the present invention is that raw material is easy to get, and technology is simple, and is easy to apply.
The specific embodiment:
Below in conjunction with embodiment to being that the serial cosmetics and the technology of main material production is described further with the human lysozyme:
Embodiment 1: a kind of human lysozyme brightens Deacne pack production
Prescription: (parts by weight)
(1) human lysozyme 0.0002-0.6
(2) carbomer CP941 0.2-0.5
(3) carboxyl methyl cellulose 0.3-0.6
(4) polyvinyl alcohol 1788 (PVA) 7-10
(5) glycerol 6-8
(6) tween 80 (T-80) 0.5-1.5
(7) azone 0.3-1.0
(8) ethanol 5-10
(9) essence 0.1-0.5
(10) water 67.6-80.45
(11) Jie Qiong-II 0.15-0.3
Technology:
1, at first raw material carbomer 941 and carboxyl methyl cellulose are dispersed in the glycerol, it is even under stirring state the ionized water adding fully to be mixed, and this process should be got ready in production in preceding 4 hours.Stir afterwards and add material polyethylene alcohol 1788 down.
In the 1 adding emulsifying pot that 2, will stir, add tween 80, azone and water-soluble silicon oil then and be stirred and heated to 75 ℃, start homogenizing, high speed homogenization 10 minutes stops high speed homogenization then, and the low speed homogenizing stopped after 15 minutes, continue to stir 10 minutes, speed of agitator is 60 rev/mins again.
3, by cooling water it is cooled off at a slow speed, add ethanol and essence continues to be stirred to cooling then, and when temperature is lower than 45 ℃, added behind human lysozyme and the Jie Qiong homogenizing 2 minutes, carry out vacuum outgas afterwards when temperature reaches 50 ℃.Be stirred to material and shut down discharging for 40 ℃.
Implementation column 2: the production of human lysozyme brightening, dispelling spots, dispelling frost
Prescription: (parts by weight)
(1) human lysozyme solution 0.0003-0.15
(2) dimethicone 200cst 2.0-5.0
(3) 18 pure 3.0-6.0
(4) hot carbon caprin/GTCC 2.5-5.0
(5) iso-octyl palmitate/GD-5103 4.0-7.0
(6) vitamin E/VE 0.3-0.7
(7) emulsifying agent Montanov 68 1.0-3.0
(8) glycerol 5-8
(9) emulsifying agent HR-S
11.0-3.0
(10) transparent fat acid HA 0.01-0.04
(11) thickening agent SepiGEL305 1.0-2.0
(12) Jie Qiong-II 1.0-2.0
(13) essence 0.10-0.20
Deionized water 70.0-75.0
Technology:
1, raw material dimethicone 200cst, 18 alcohol, hot carbon caprin/GTCC, iso-octyl palmitate/GD-5103, vitamin E/VE, emulsifying agent Montanov 68 are added in the oil phase material pot, be stirred and heated to 85 ℃; 2, with raw material glycerol, emulsifying agent HR-S
1, transparent fat acid HA, Jie Qiong-II and deionized water add in the emulsifying pot heated and stirred to 87-89 ℃; 3, start vacuum pump the emulsifying pot is evacuated down to 0.06Mpa, stop vacuum, oil phase was drawn in the emulsifying pot high speed homogenization 10 minutes, speed of agitator 70 changes, and stops behind the high speed homogenization; Low speed homogenizing 10 minutes stops homogenizing, continues to stir 10 minutes, and rotating speed is 60 commentaries on classics; 4, water flowing is cooled off at a slow speed, adds the final vacuum degassing in 2 minutes of raw material thickening agent SepiGEL305 homogenizing during 60 ℃ of temperature; 5, in the time of 45 ℃, add raw material deionized water and human lysozyme solution, shut down discharging when being stirred to 40 ℃.
Embodiment 3: human lysozyme brightens essence (transparent type) and (emulsion-type) produced
Prescription: (parts by weight)
1. human lysozyme solution 0.00018-0.18,2. carbomer CP9410.2-0.5,3. 4. VE (vitamin E) 0.5-1.0,5. HA (transparent fat acid) 0.05-0.15,6. deionized water 90-93,7. Jie Qiong-II0.1-0.3,8. essence 0.1-0.3,9. EDTA-Na0.08-0.15 of glycerol 5-8:
Technology:
Raw material carbomer CP941 and HA (transparent fat acid) are uniformly dispersed in glycerol, add then in the raw material deionized water, this mixture is poured in the reaction cylinder, heating 80 ℃ of mixing speeds is 70 rev/mins, treat that carbomer CP941 all stops heating after the dissolving, add raw material VE (vitamin E) and human lysozyme solution and Jie Qiong-II, essence when water flowing is cooled to 45 ℃ of temperature, EDTA-Na low speed homogenizing outgased discharging when temperature reaches 40 ℃ in 5 minutes.Preparation whitening essence (emulsion-type) its prescription is: 1. human lysozyme solution 0.000018-0.18,2. thickening agent (SEPIGEL502) 1.0-3.0,3. glycerol 5-7,4. silicone grease (SF-9031) 0.2-0.7,5. castor oil hydrogenated (PEG40) 0.2-0.6,6. water-soluble silicon oil 0.1-0.5,7. HR-S
10.3-1.0,8. deionized water 90,9. outstanding agate II0.1-0.3,10. essence 0.1-0.3.Processing step is: raw material thickening agent (SEPIGEL502) and silicone grease (SF-9031) are dispersed in to pour the back that stirs in the reaction cylinder in the glycerol into standby; Again raw material castor oil hydrogenated (PEG40), water-soluble silicon oil, HR-Si, deionized water are mixed and pour that pouring into lentamente when treating that temperature is reduced to 45 ℃ behind 60 ℃ of homogenizing of heating in the oil phase pot in the above-mentioned standby material walks around 70 stirs under the speed into, when stopping to 1/2 the time, that stirs that continuation will be left after 5 seconds 1/2 continues to stir and adds behind human lysozyme solution, outstanding agate II, the essence blowing after the vacuum outgas in 5 seconds of low speed homogenizing.
Embodiment 4: human lysozyme brightens moisturizer production after taking a shower
Prescription: (parts by weight) are human lysozyme solution 0.00001-0.05,2. thickening agent (SEPIGEL502) 1.5-3.5,3. glycerol 6-9,4. manna alditol fat silanol 2-5,5. castor oil hydrogenated (PEG40) 0.5-1.5,6. water-soluble silicon oil 0.2-1.0,7. HR-S 1.
10.2-1.0,8. deionized water 85.2,9. outstanding agate II0.1-0.3,10. essence 0.1-0.3
2. and 4. technology: A, stir in adding raw material 3.; B, with raw material 5. 6. 7. add raw material 8. in, pour into and stir the back in the reaction cylinder and open high speed homogenization minute; Pour the B phase high speed homogenizing 10 minutes of reaction cylinder under C, the state that A is stirred mutually lentamente into, add raw material then 1. 9. 10., and minute vacuum outgas of low speed homogenizing gets final product blowing.Add raw material then 1. 9. 10., and minute vacuum outgas of low speed homogenizing gets final product blowing.
Embodiment 5: human lysozyme brightens the production of moistening skin and eliminating spot essence
Prescription (parts by weight): 1. human lysozyme solution 0.0005-0.2,2. hyaluronic acid (HA) 0.05-0.2,3. glycerol 6-8,4. EDTA-Na0.05-0.2, the 5. auxilliary amine fat silanol 3.0-5.0 of hydroxyl, 6. HANSHENGJIAO 0.3-0.5,7. outstanding agate II0.1-0.3,8. deionized water 80-93,9. essence 11-15
Technology: with raw material 2. 4. 6. be dispersed in raw material 3. in, 5. and 8. add then and pour in the reaction cylinder after raw material fully stirs, 9. 1. room temperature low speed homogenizing 5 seconds add afterwards and carry out the stirring that rotating speed 60 changes, degassing back blowing.
Claims (7)
1, a kind of human lysozyme series cosmetics, it is characterized in that: the main component of cosmetics is human lysozymes, the active unit that contains human lysozyme in its every gram cosmetics is 150U-600 ten thousand U, and the human lysozyme content in every gram cosmetics is that the purity of 0.018-200mg, human lysozyme is 85%-99.52%.
2, a kind of human lysozyme series cosmetics according to claim 1, it is characterized in that described cosmetics are the bean whitening mask of dispelling of human lysozyme, it is formed and parts by weight content is human lysozyme 0.0002-0.6 part, carbomer CP941 0.2-0.5 part, carboxyl methyl cellulose 0.3-0.6 part, polyvinyl alcohol 1788 7-10 parts, glycerol 6-8 part, tween 80 0.5-1.5 part, azone 0.3-1.0 part, ethanol 5-10 part, essence 0.1-0.5 part, water 67.6-80.45 part, Jie Qiong-II 0.15-0.3 part; The purity of its human lysozyme is 89%-99%.
3, a kind of human lysozyme series cosmetics according to claim 1, it is characterized in that described cosmetics are the brightening, dispelling spots, dispelling frost of human lysozyme, its composition and parts by weight content behaviour lysozyme soln 0.0003-0.15 part, dimethicone 200cst 2.0-5.0 part, 18 pure 3.0-6.0 parts, hot carbon caprin 2.5-5.0 part, iso-octyl palmitate 4.0-7.0 part, vitamin E 0.3-0.7 part, emulsifying agent Montanov 68 1.0-3.0 parts, glycerol 5-8 part, emulsifying agent HR-S
11.0-3.0 part, transparent fat acid HA0.01-0.04 part, thickening agent SepiGEL305 1.0-2.0 part, Jie Qiong-II1.0-2.0 part, essence 0.10-0.20 part, deionized water 70.0-75.0 part; The purity of its human lysozyme is 89%-99%.
4, a kind of human lysozyme series cosmetics according to claim 1, it is characterized in that described cosmetics are that the transparent type of human lysozyme brightens essence and emulsion-type whitening essence, composition and parts by weight content that the transparent type of human lysozyme brightens essence are: human lysozyme solution 0.00018-0.18 part, carbomer CP941 0.2-0.5 part, glycerol 5-8 part, vitamin E 0.5-1.0 part, transparent fat acid 0.05-0.15 part, deionized water 90-93 part, Jie Qiong-II 0.1-0.3 part, essence 0.1-0.3 part, EDTA-Na 0.08-0.15 part; The composition of emulsion-type whitening essence and parts by weight content are: human lysozyme solution 0.000018-0.18 part, thickening agent SEPIGEL502 1.0-3.0 part, glycerol 5-7 part, silicone grease SF-9031 0.2-0.7 part, castor oil hydrogenated 0.2-0.6 part, water-soluble silicon oil 0.1-0.5 part, HR-S
10.3-1.0 part, 90 parts of deionized waters, outstanding agate II 0.1-0.3 part, essence 0.1-0.3 part; The purity of its human lysozyme is 89%-99%.
5, a kind of human lysozyme series cosmetics according to claim 1, it is characterized in that described cosmetics are to brighten moisturizer after the shower of human lysozyme, it is formed and parts by weight content behaviour lysozyme soln 0.00001-0.05 part, thickening agent SEPIGEL5021.5-3.5 part, glycerol 6-9 part, manna alditol fat silanol 2-5 part, castor oil hydrogenated 0.5-1.5 part, water-soluble silicon oil 0.2-1.0 part, HR-S
10.2-1.0 part, 85.2 parts of deionized waters, outstanding agate II 0.1-0.3 part, essence 0.1-0.3 part; The purity of its human lysozyme is 89%-99%.
6, a kind of human lysozyme series cosmetics according to claim 1, it is characterized in that described cosmetics be human lysozyme brighten the moistening skin and eliminating spot essence, it is formed and parts by weight content behaviour lysozyme soln 0.0005-0.2 part, hyaluronic acid 0.05-0.2 part, glycerol 6-8 part, EDTA-Na 0.05-0.2 part, hydroxyl are assisted amine fat silanol 3.0-5.0 part, HANSHENGJIAO 0.3-0.5 part, outstanding agate II 0.1-0.3 part, deionized water 80-93 part, essence 11-15 part; The purity of its human lysozyme is 89%-99%.
7, a kind of human lysozyme series cosmetics according to claim 1, it is characterized in that preparation technology is as follows: at first the pure product of human lysozyme are added make in 15% the water behind the human lysozyme aqueous solution standby, after then will the various raw material homogeneous dispersions except that human lysozyme, stir again, emulsifying postcooling to 45 degree, the human lysozyme for preparing is poured into, be stirred to uniform temperature through vacuum outgas and get final product.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02132412 CN1205917C (en) | 2002-06-05 | 2002-06-05 | Human lysozyme series cosmetics and its preparation method |
| AU2003246082A AU2003246082A1 (en) | 2002-06-05 | 2003-05-28 | A series of cosmetic products containing human lysozyme (hlz) and their preparing method |
| PCT/CN2003/000403 WO2003103621A1 (en) | 2002-06-05 | 2003-05-28 | A series of cosmetic products containing human lysozyme (hlz) and their preparing method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02132412 CN1205917C (en) | 2002-06-05 | 2002-06-05 | Human lysozyme series cosmetics and its preparation method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1410051A CN1410051A (en) | 2003-04-16 |
| CN1205917C true CN1205917C (en) | 2005-06-15 |
Family
ID=4746755
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 02132412 Expired - Fee Related CN1205917C (en) | 2002-06-05 | 2002-06-05 | Human lysozyme series cosmetics and its preparation method |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN1205917C (en) |
| AU (1) | AU2003246082A1 (en) |
| WO (1) | WO2003103621A1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1679504A (en) * | 2005-01-26 | 2005-10-12 | 安米 | Use of human lysozyme in cosmetics for treating acne |
| CN106176277A (en) * | 2016-09-06 | 2016-12-07 | 陕西慧康生物科技有限责任公司 | Gene recombinant human lysozyme facial film and preparation method thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5533408A (en) * | 1978-08-30 | 1980-03-08 | Eisai Co Ltd | Immunity-increasing agent |
| JPS61158793A (en) * | 1984-11-14 | 1986-07-18 | Takeda Chem Ind Ltd | Gene for synthesis of human lysozyme |
| DE3540075A1 (en) * | 1985-11-12 | 1987-05-14 | Boehringer Ingelheim Int | HUMAN LYSOZYM |
-
2002
- 2002-06-05 CN CN 02132412 patent/CN1205917C/en not_active Expired - Fee Related
-
2003
- 2003-05-28 AU AU2003246082A patent/AU2003246082A1/en not_active Abandoned
- 2003-05-28 WO PCT/CN2003/000403 patent/WO2003103621A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003246082A8 (en) | 2003-12-22 |
| CN1410051A (en) | 2003-04-16 |
| WO2003103621A1 (en) | 2003-12-18 |
| AU2003246082A1 (en) | 2003-12-22 |
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