CN121646476A - 用于治疗淀粉样变性的疫苗 - Google Patents

用于治疗淀粉样变性的疫苗

Info

Publication number
CN121646476A
CN121646476A CN202480051335.8A CN202480051335A CN121646476A CN 121646476 A CN121646476 A CN 121646476A CN 202480051335 A CN202480051335 A CN 202480051335A CN 121646476 A CN121646476 A CN 121646476A
Authority
CN
China
Prior art keywords
ttr
peptide
vaccine
seq
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202480051335.8A
Other languages
English (en)
Chinese (zh)
Inventor
奥班·米夏隆
斯特凡·默泽
扬·格里姆
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Neuroimmunology Co ltd
Original Assignee
Neuroimmunology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neuroimmunology Co ltd filed Critical Neuroimmunology Co ltd
Publication of CN121646476A publication Critical patent/CN121646476A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0007—Nervous system antigens; Prions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6081—Albumin; Keyhole limpet haemocyanin [KLH]

Landscapes

  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN202480051335.8A 2023-06-07 2024-06-07 用于治疗淀粉样变性的疫苗 Pending CN121646476A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP23178124.6 2023-06-07
EP23178124 2023-06-07
EP23212300.0 2023-11-27
EP23212300 2023-11-27
PCT/EP2024/065817 WO2024251997A1 (fr) 2023-06-07 2024-06-07 Vaccin pour le traitement de l'amyloïdose

Publications (1)

Publication Number Publication Date
CN121646476A true CN121646476A (zh) 2026-03-10

Family

ID=91375092

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202480051335.8A Pending CN121646476A (zh) 2023-06-07 2024-06-07 用于治疗淀粉样变性的疫苗

Country Status (3)

Country Link
EP (1) EP4724088A1 (fr)
CN (1) CN121646476A (fr)
WO (1) WO2024251997A1 (fr)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010195710A (ja) * 2009-02-25 2010-09-09 Kumamoto Univ アミロイド線維形成抑制剤及びその利用
EP2953970A4 (fr) 2013-02-08 2016-06-29 Misfolding Diagnostics Inc Anticorps anti-transthyrétine et leurs utilisations
WO2015092077A1 (fr) 2013-12-20 2015-06-25 Neurimmune Holding Ag Thérapie de l'amyloïdose de la transthyrétine (ttr) à base d'anticorps, et anticorps d'origine humaine afférents
CN106574258B (zh) 2014-01-29 2021-03-30 Km生物医药股份公司 抗-运甲状腺素蛋白人源化抗体
KR102240417B1 (ko) 2014-01-29 2021-04-13 케이엠 바이올로직스 가부시키가이샤 항-트랜스티레틴 인간 항체
CN111315213B (zh) 2017-10-06 2023-09-12 普罗塞纳生物科学有限公司 抗甲状腺素运载蛋白抗体
WO2023099788A1 (fr) * 2021-12-03 2023-06-08 Neurimmune Ag Nouveau dosage de puissance pour des médicaments à base d'anticorps et moyens utiles associés

Also Published As

Publication number Publication date
WO2024251997A1 (fr) 2024-12-12
EP4724088A1 (fr) 2026-04-15

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