CN121646582A - 4-氯-5-[4-(2,6-二氯苯基)磺酰基哌嗪-1-基]-1-苯并呋喃-2-甲酸的氨丁三醇盐及其各种形式 - Google Patents

4-氯-5-[4-(2,6-二氯苯基)磺酰基哌嗪-1-基]-1-苯并呋喃-2-甲酸的氨丁三醇盐及其各种形式

Info

Publication number
CN121646582A
CN121646582A CN202480046191.7A CN202480046191A CN121646582A CN 121646582 A CN121646582 A CN 121646582A CN 202480046191 A CN202480046191 A CN 202480046191A CN 121646582 A CN121646582 A CN 121646582A
Authority
CN
China
Prior art keywords
disease
ray diffraction
tromethamine salt
crystalline form
diffraction pattern
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202480046191.7A
Other languages
English (en)
Chinese (zh)
Inventor
R·达泰尔
J·冯德舍尔
D·桑普森
N·菲利蓬
J·瓦库斯
J·勒鲁迪埃
S·韦尔纳
F·理查-蒂伯吉安
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Enyou Pharmaceutical
Original Assignee
Enyou Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Enyou Pharmaceutical filed Critical Enyou Pharmaceutical
Publication of CN121646582A publication Critical patent/CN121646582A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN202480046191.7A 2023-07-13 2024-07-12 4-氯-5-[4-(2,6-二氯苯基)磺酰基哌嗪-1-基]-1-苯并呋喃-2-甲酸的氨丁三醇盐及其各种形式 Pending CN121646582A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP23306215 2023-07-13
EP23306215.7 2023-07-13
PCT/EP2024/069807 WO2025012425A1 (fr) 2023-07-13 2024-07-12 Sel de trométhamine d'acide 4-chloro-5-[4-(2,6-dichlorophényl)sulfonylpipérazin-1-yl]-1-benzofuran-2-carboxylique et diverses formes de celui-ci

Publications (1)

Publication Number Publication Date
CN121646582A true CN121646582A (zh) 2026-03-10

Family

ID=87553924

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202480046191.7A Pending CN121646582A (zh) 2023-07-13 2024-07-12 4-氯-5-[4-(2,6-二氯苯基)磺酰基哌嗪-1-基]-1-苯并呋喃-2-甲酸的氨丁三醇盐及其各种形式

Country Status (3)

Country Link
CN (1) CN121646582A (fr)
MX (1) MX2026000403A (fr)
WO (1) WO2025012425A1 (fr)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2110374A1 (fr) 2008-04-18 2009-10-21 Merck Sante Dérivés de benzofurane, benzothiophène, benzothiazol en tant que modulateurs FXR
US10961583B2 (en) 2017-10-11 2021-03-30 Regeneron Phramaceuticals, Inc. Inhibition of HSD17B13 in the treatment of liver disease in patients expressing the PNPLA3 I148M variation
CA3233305A1 (fr) * 2019-02-19 2020-08-27 Gilead Sciences, Inc. Formes solides d'agonistes de fxr
US12030861B1 (en) * 2023-07-13 2024-07-09 Enyo Pharma L-lysine salt of 4-chloro-5-[4-(2,6-dichlorophenyl)sulfonylpiperazin-1-yl]-1-benzofuran-2-carboxylic acid and various forms thereof

Also Published As

Publication number Publication date
MX2026000403A (es) 2026-03-02
WO2025012425A1 (fr) 2025-01-16

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