CN1226148A - 改进分子试剂光激活选择性的方法 - Google Patents

改进分子试剂光激活选择性的方法 Download PDF

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Publication number
CN1226148A
CN1226148A CN97196827A CN97196827A CN1226148A CN 1226148 A CN1226148 A CN 1226148A CN 97196827 A CN97196827 A CN 97196827A CN 97196827 A CN97196827 A CN 97196827A CN 1226148 A CN1226148 A CN 1226148A
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CN
China
Prior art keywords
coumarin
light
tissue
molecular agent
rhodamine
Prior art date
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Pending
Application number
CN97196827A
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English (en)
Chinese (zh)
Inventor
W·G·费歇尔
E·A·沃彻特
H·C·德斯
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Photogen Inc
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Photogen Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24973830&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN1226148(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Photogen Inc filed Critical Photogen Inc
Publication of CN1226148A publication Critical patent/CN1226148A/zh
Pending legal-status Critical Current

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/008—Two-Photon or Multi-Photon PDT, e.g. with upconverting dyes or photosensitisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00017—Electrical control of surgical instruments
    • A61B2017/00022—Sensing or detecting at the treatment site
    • A61B2017/00057—Light
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/062—Photodynamic therapy, i.e. excitation of an agent
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Nanotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Radiation-Therapy Devices (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN97196827A 1996-10-30 1997-10-28 改进分子试剂光激活选择性的方法 Pending CN1226148A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/739,801 1996-10-30
US08/739,801 US5829448A (en) 1996-10-30 1996-10-30 Method for improved selectivity in photo-activation of molecular agents

Publications (1)

Publication Number Publication Date
CN1226148A true CN1226148A (zh) 1999-08-18

Family

ID=24973830

Family Applications (1)

Application Number Title Priority Date Filing Date
CN97196827A Pending CN1226148A (zh) 1996-10-30 1997-10-28 改进分子试剂光激活选择性的方法

Country Status (14)

Country Link
US (3) US5829448A (2)
EP (1) EP0977592A4 (2)
JP (1) JP2000511929A (2)
KR (1) KR20000035893A (2)
CN (1) CN1226148A (2)
AU (1) AU716507B2 (2)
BR (1) BR9712599A (2)
CA (1) CA2252783A1 (2)
IL (1) IL128355A (2)
IN (1) IN186854B (2)
IS (1) IS5006A (2)
NO (1) NO991492L (2)
NZ (1) NZ334190A (2)
WO (1) WO1998018399A1 (2)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111592920A (zh) * 2020-05-21 2020-08-28 新沂百川畅银新能源有限公司 一种沼气脱硫净化工艺

Families Citing this family (137)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5912257A (en) 1995-09-06 1999-06-15 The Research Foundation Of State University Of New York Two-photon upconverting dyes and applications
US7036516B1 (en) 1996-10-30 2006-05-02 Xantech Pharmaceuticals, Inc. Treatment of pigmented tissues using optical energy
US7390668B2 (en) * 1996-10-30 2008-06-24 Provectus Pharmatech, Inc. Intracorporeal medicaments for photodynamic treatment of disease
US6493570B1 (en) 1998-11-02 2002-12-10 Photogen, Inc. Method for improved imaging and photodynamic therapy
US6331286B1 (en) * 1998-12-21 2001-12-18 Photogen, Inc. Methods for high energy phototherapeutics
US6525862B2 (en) 1996-10-30 2003-02-25 Photogen, Inc. Methods and apparatus for optical imaging
US20060095097A1 (en) * 1996-10-30 2006-05-04 Provectus Devicetech, Inc. Treatment of pigmented tissue using optical energy
US7353829B1 (en) 1996-10-30 2008-04-08 Provectus Devicetech, Inc. Methods and apparatus for multi-photon photo-activation of therapeutic agents
US5995867A (en) * 1997-03-19 1999-11-30 Lucid Inc Cellular surgery utilizing confocal microscopy
US8974363B2 (en) 1997-12-11 2015-03-10 Provectus Pharmatech, Inc. Topical medicaments and methods for photodynamic treatment of disease
WO1999054784A1 (en) 1998-04-21 1999-10-28 University Of Connecticut Free-form nanofabrication using multi-photon excitation
US6223071B1 (en) 1998-05-01 2001-04-24 Dusa Pharmaceuticals Inc. Illuminator for photodynamic therapy and diagnosis which produces substantially uniform intensity visible light
US8557298B2 (en) 1998-08-06 2013-10-15 Provectus Pharmatech, Inc. Medicaments for chemotherapeutic treatment of disease
CN1132557C (zh) 1998-08-06 2003-12-31 福托金公司 靶向局部治疗疾病的装置
US20090117199A1 (en) * 1998-08-06 2009-05-07 Scott Timothy C Method of treatment of cancer
US6986740B2 (en) * 1998-11-02 2006-01-17 Xantech Pharmaceuticals, Inc. Ultrasound contrast using halogenated xanthenes
US9192780B2 (en) 1998-11-30 2015-11-24 L'oreal Low intensity light therapy for treatment of retinal, macular, and visual pathway disorders
US6283956B1 (en) * 1998-11-30 2001-09-04 David H. McDaniels Reduction, elimination, or stimulation of hair growth
US20060212025A1 (en) 1998-11-30 2006-09-21 Light Bioscience, Llc Method and apparatus for acne treatment
US6936044B2 (en) * 1998-11-30 2005-08-30 Light Bioscience, Llc Method and apparatus for the stimulation of hair growth
US6887260B1 (en) 1998-11-30 2005-05-03 Light Bioscience, Llc Method and apparatus for acne treatment
US8470296B2 (en) * 1998-12-21 2013-06-25 Provectus Pharmatech, Inc. Intracorporeal medicaments for high energy phototherapeutic treatment of disease
US20020001567A1 (en) * 1998-12-21 2002-01-03 Photogen, Inc. Intracorporeal medicaments for high energy phototherapeutic treatment of disease
US7384623B1 (en) 1998-12-21 2008-06-10 Provectus Pharmatech, Inc. High energy phototherapeutic agents
US6454789B1 (en) 1999-01-15 2002-09-24 Light Science Corporation Patient portable device for photodynamic therapy
JP2002534483A (ja) * 1999-01-15 2002-10-15 ライト サイエンシーズ コーポレイション 代謝性骨障害または骨転移のための治療的組成物
JP2002534218A (ja) * 1999-01-15 2002-10-15 ライト サイエンシーズ コーポレイション 非侵襲性の脈管療法
US6602274B1 (en) 1999-01-15 2003-08-05 Light Sciences Corporation Targeted transcutaneous cancer therapy
EP1161924B1 (en) * 1999-02-12 2006-12-20 Alexei Ivanovich Trushin Method for diagnosing proliferation regions and device for realising the same
WO2001006505A1 (en) * 1999-07-15 2001-01-25 Trid Store Ip, L.L.C. Multilayer fluorescent optical disc with photosensitive fluorescent material
AU775373B2 (en) 1999-10-01 2004-07-29 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
US7167615B1 (en) 1999-11-05 2007-01-23 Board Of Regents, The University Of Texas System Resonant waveguide-grating filters and sensors and methods for making and using same
US6319273B1 (en) * 1999-12-16 2001-11-20 Light Sciences Corporation Illuminating device for treating eye disease
US7897140B2 (en) 1999-12-23 2011-03-01 Health Research, Inc. Multi DTPA conjugated tetrapyrollic compounds for phototherapeutic contrast agents
EP1267935A2 (en) * 2000-01-12 2003-01-02 Light Sciences Corporation Novel treatment for eye disease
US7331350B2 (en) 2000-02-11 2008-02-19 The General Hospital Corporation Photochemical tissue bonding
US7073510B2 (en) * 2000-02-11 2006-07-11 The General Hospital Corporation Photochemical tissue bonding
US8215314B2 (en) * 2000-02-11 2012-07-10 The General Hospital Corporation Photochemical tissue bonding
US7193706B2 (en) 2000-08-02 2007-03-20 Arizona Board Of Regents, Acting On Behalf Of Arizona State University Computer interfaced scanning fluorescence lifetime microscope applied to directed evolution
JP4659300B2 (ja) * 2000-09-13 2011-03-30 浜松ホトニクス株式会社 レーザ加工方法及び半導体チップの製造方法
AU2002245345A1 (en) 2001-01-30 2002-08-12 Board Of Trustees Operating Michigan State University Control system and apparatus for use with laser excitation or ionization
US7567596B2 (en) * 2001-01-30 2009-07-28 Board Of Trustees Of Michigan State University Control system and apparatus for use with ultra-fast laser
US7583710B2 (en) * 2001-01-30 2009-09-01 Board Of Trustees Operating Michigan State University Laser and environmental monitoring system
US8208505B2 (en) * 2001-01-30 2012-06-26 Board Of Trustees Of Michigan State University Laser system employing harmonic generation
US7609731B2 (en) * 2001-01-30 2009-10-27 Board Of Trustees Operating Michigan State University Laser system using ultra-short laser pulses
US7973936B2 (en) * 2001-01-30 2011-07-05 Board Of Trustees Of Michigan State University Control system and apparatus for use with ultra-fast laser
US7450618B2 (en) * 2001-01-30 2008-11-11 Board Of Trustees Operating Michigan State University Laser system using ultrashort laser pulses
US6894161B2 (en) * 2001-03-27 2005-05-17 The University Of British Columbia Methods and compositions for photo-cross linking photoactive compounds to target tissue
EP1372552B1 (de) * 2001-03-27 2017-03-01 WaveLight GmbH Vorrichtung zur bearbeitung und diagnose von augengewebe
WO2002084271A2 (en) * 2001-04-16 2002-10-24 The Regents Of The University Of California Methods and sensors for luminescent and optoelectronic detection and analysis of polynucleotides
US20030103995A1 (en) * 2001-06-04 2003-06-05 Hamblin Michael R. Detection and therapy of vulnerable plaque with photodynamic compounds
EP1312353A1 (en) * 2001-11-16 2003-05-21 Ecole Polytechnique Federale De Lausanne (Epfl) Method for hair removal
US7494502B2 (en) 2002-02-11 2009-02-24 Keraderm, Llc Alteration of the skin and nail for the prevention and treatment of skin and nail infections
US6960201B2 (en) * 2002-02-11 2005-11-01 Quanticum, Llc Method for the prevention and treatment of skin and nail infections
US20030191458A1 (en) * 2002-04-03 2003-10-09 Cornelius Diamond Light-activated drug delivery method and device
EP1517684B1 (en) 2002-06-27 2009-07-22 Health Research, Inc. Fluorinated chlorin and bacteriochlorin photosensitizers for photodynamic therapy
WO2004005289A2 (en) 2002-07-02 2004-01-15 Health Research, Inc. Efficient synthesis of pyropheophorbide a and its derivatives
US20040156743A1 (en) * 2002-08-28 2004-08-12 Eric Bornstein Near infrared microbial elimination laser system
US8506979B2 (en) * 2002-08-28 2013-08-13 Nomir Medical Technologies, Inc. Near-infrared electromagnetic modification of cellular steady-state membrane potentials
US20080131968A1 (en) * 2002-08-28 2008-06-05 Nomir Medical Technologies, Inc. Near-infrared electromagnetic modification of cellular steady-state membrane potentials
US7713294B2 (en) 2002-08-28 2010-05-11 Nomir Medical Technologies, Inc. Near infrared microbial elimination laser systems (NIMEL)
WO2004029690A1 (en) * 2002-09-27 2004-04-08 Saloma Caesar A Two-color (two-photon) excitation with focused excitation beams and a raman shifter
EP2221810B1 (en) * 2002-10-10 2014-09-24 Landauer, Inc. Method of erasing information stored on a luminescent data storage medium comprising aluminium oxide base material
KR20060041161A (ko) 2003-04-10 2006-05-11 라이트 바이오사이언스, 엘엘씨 세포 증식 및 유전자 발현의 조절을 위한 광조절 방법 및광조절 장치
AU2003292591A1 (en) * 2003-06-20 2005-01-04 Keio University Photodynamic therapy apparatus, method for controlling photodynamic therapy apparatus, and photodynamic therapy method
EP1648385B1 (en) * 2003-07-31 2016-05-04 Gentlewaves Llc System and method for the photodynamic treatment of skin
WO2005019800A2 (en) * 2003-08-19 2005-03-03 Cedars-Sinai Medical Center Method for fluorescence lifetime imaging microscopy and spectroscopy
US20050053895A1 (en) 2003-09-09 2005-03-10 The Procter & Gamble Company Attention: Chief Patent Counsel Illuminated electric toothbrushes emitting high luminous intensity toothbrush
US20050085455A1 (en) * 2003-10-16 2005-04-21 Light Sciences Corporation Photodynamic therapy for local adipocyte reduction
WO2006015493A1 (en) * 2004-08-13 2006-02-16 Derma Laser Inc Method for the treatment of mammalian skin tissues via pulse irradiation in the presence of a photoactive compound
JPWO2006049132A1 (ja) * 2004-11-02 2008-05-29 学校法人慶應義塾 光線力学的治療装置
CA2526327C (en) * 2004-11-09 2014-01-07 Institut National D'optique Device for transmitting multiple optically-encoded stimulation signals to multiple cell locations
US7280078B2 (en) 2004-11-20 2007-10-09 Scenterra, Inc. Sensor for detecting high frequency signals
EP1825560A4 (en) * 2004-11-20 2010-09-15 Kenneth E Salsman DEVICE FOR EMISSION OF HIGH FREQUENCY SIGNALS
EP1851532A1 (en) * 2005-02-14 2007-11-07 Board of Trustees of Michigan State University Ultra-fast laser system
WO2006128442A1 (de) * 2005-05-31 2006-12-07 W.O.M. World Of Medicine Ag Verfahren und vorrichtung zur optischen charakterisierung von gewebe
CA2615799A1 (en) * 2005-07-21 2007-02-01 Nomir Medical Technologies, Inc. Near infrared microbial elimination laser system (nimels)
US8618470B2 (en) 2005-11-30 2013-12-31 Board Of Trustees Of Michigan State University Laser based identification of molecular characteristics
RU2314023C2 (ru) * 2006-01-30 2008-01-10 Михаил Витальевич Мошнин Способ определения момента появления псораленов в коже пациента
US9018562B2 (en) * 2006-04-10 2015-04-28 Board Of Trustees Of Michigan State University Laser material processing system
WO2007123518A1 (en) * 2006-04-21 2007-11-01 Cedars-Sinai Medical Center Multiple imaging and/or spectroscopic modality probe
US20080275432A1 (en) * 2006-05-11 2008-11-06 Ceramoptec Industries, Inc. Photodynamic foam composition and sclerosis treatment
CA2670711A1 (en) * 2006-12-12 2008-06-19 Nomir Medical Technologies, Inc. Near-infrared electromagnetic modification of cellular steady-state membrane potentials
US20080208295A1 (en) * 2007-02-28 2008-08-28 Cumbie William E Phototherapy Treatment and Device to Improve the Appearance of Nails and skin
US8951561B2 (en) * 2007-08-06 2015-02-10 Duke University Methods and systems for treating cell proliferation disorders using plasmonics enhanced photospectral therapy (PEPST) and exciton-plasmon enhanced phototherapy (EPEP)
US8376013B2 (en) 2008-03-11 2013-02-19 Duke University Plasmonic assisted systems and methods for interior energy-activation from an exterior source
AU2016210665B2 (en) * 2007-04-08 2017-12-07 Immunolight, Llc Methods and systems for treating cell proliferation disorders
US9358292B2 (en) 2007-04-08 2016-06-07 Immunolight, Llc Methods and systems for treating cell proliferation disorders
WO2015195896A1 (en) 2014-06-19 2015-12-23 Immunolight, Llc Methods and systems for treating cell proliferation disorders with psoralen derivatives
US20140324138A1 (en) * 2007-05-09 2014-10-30 Massachusetts Institute Of Technology Wirelessly-powered illumination of biological tissue
US20090104212A1 (en) * 2007-08-06 2009-04-23 Immunolight Methods and systems for treating cell proliferation disorders using two-photon simultaneous absorption
WO2009038791A1 (en) 2007-09-18 2009-03-26 Applied Biosystems Inc. Methods, systems and apparatus for light concentrating mechanisms
US20090156881A1 (en) * 2007-10-15 2009-06-18 Stokes John P Convergent well irradiating plaque for choroidal melanoma
US8684898B2 (en) * 2007-10-18 2014-04-01 The Invention Science Fund I Llc Ionizing-radiation-responsive compositions, methods, and systems
US9557635B2 (en) * 2007-10-18 2017-01-31 Gearbox, Llc Ionizing-radiation-responsive compositions, methods, and systems
US8529426B2 (en) 2007-10-18 2013-09-10 The Invention Science Fund I Llc Ionizing-radiation-responsive compositions, methods, and systems
US8168958B2 (en) * 2007-10-18 2012-05-01 The Invention Science Fund I, Llc Ionizing-radiation-responsive compositions, methods, and systems
US20090104113A1 (en) * 2007-10-18 2009-04-23 Searete Llc Ionizing-radiation-responsive compositions, methods, and systems
US8164074B2 (en) * 2007-10-18 2012-04-24 The Invention Science Fund I, Llc Ionizing-radiation-responsive compositions, methods, and systems
US8227204B2 (en) * 2007-10-18 2012-07-24 The Invention Science Fund I, Llc Ionizing-radiation-responsive compositions, methods, and systems
US9439897B2 (en) 2007-11-06 2016-09-13 Immunolight, Llc Use of psoralen derivatives and combination therapy for treatment of cell proliferation disorders
US8311069B2 (en) 2007-12-21 2012-11-13 Board Of Trustees Of Michigan State University Direct ultrashort laser system
DE102008011811B3 (de) * 2008-02-29 2009-10-15 Anton Dr. Kasenbacher Dentales Laserbearbeitungsgerät zur Bearbeitung von Zahnmaterial
US9907976B2 (en) 2011-07-08 2018-03-06 Immunolight, Llc Phosphors and scintillators for light stimulation within a medium
EP2268311A4 (en) 2008-04-04 2014-08-27 Immunolight Llc NON-INVASIVE SYSTEMS AND IN SITU PHOTOBIOMODULATION METHODS
US8770203B2 (en) 2008-07-14 2014-07-08 Immunolight, Llc. Advanced methods and systems for treating cell proliferation disorders
DE102009005194B4 (de) * 2009-01-20 2016-09-08 Anton Kasenbacher Laserbearbeitungsgerät zur Bearbeitung eines Materials
EP2211430A3 (en) * 2009-01-23 2015-05-27 Board of Trustees of Michigan State University Laser autocorrelation system
US8861075B2 (en) 2009-03-05 2014-10-14 Board Of Trustees Of Michigan State University Laser amplification system
TWI511756B (zh) 2009-04-21 2015-12-11 伊穆諾萊特公司 用以修飾介導生物活性或與生物活性有關之標靶結構之醫藥組合物或套組
US20110054305A1 (en) * 2009-08-30 2011-03-03 Stephen Eliot Zweig Photon upconverting implantable medical devices
US20110275686A1 (en) * 2009-12-11 2011-11-10 Biolitec, Inc. Nanoparticle carrier systems based on poly(dl-lactic-co-glycolic acid) (plga) for photodynamic therapy (pdt)
US8630322B2 (en) * 2010-03-01 2014-01-14 Board Of Trustees Of Michigan State University Laser system for output manipulation
US9642687B2 (en) 2010-06-15 2017-05-09 The Procter & Gamble Company Methods for whitening teeth
US9095414B2 (en) * 2011-06-24 2015-08-04 The Regents Of The University Of California Nonlinear optical photodynamic therapy (NLO-PDT) of the cornea
US9257206B2 (en) * 2011-12-02 2016-02-09 The Charles Stark Draper Laboratory, Inc. Adiabatic rapid passage atomic beamsplitter using frequency-swept coherent laser beam pairs
US10549112B2 (en) 2012-07-20 2020-02-04 The General Hospital Corporation Apparatus for tissue irradiation and methods and kits utilizing the same
WO2014015274A1 (en) 2012-07-20 2014-01-23 The General Hospital Corporation Methods for tissue passivation
US20140140959A1 (en) 2012-10-05 2014-05-22 Aladar A. Szalay Energy Absorbing-Based Diagnostic and Therapeutic Methods Employing Nucleic Acid Molecules Encoding Chromophore-Producing Enzymes
WO2014168734A1 (en) 2013-03-15 2014-10-16 Cedars-Sinai Medical Center Time-resolved laser-induced fluorescence spectroscopy systems and uses thereof
EP2988693B1 (en) * 2013-04-25 2019-06-12 Koninklijke Philips N.V. Non-invasive device for treatment of the skin using laser light
AU2014290513B2 (en) 2013-07-18 2017-07-27 The General Hospital Corporation Vessel treatment systems, methods, and kits
WO2015108991A2 (en) 2014-01-17 2015-07-23 Imra America, Inc. Laser-based modification of transparent materials
CA2947392C (en) 2014-04-29 2022-11-01 Theralase Technologies, Inc. Apparatus and method for multiwavelength photodynamic therapy
US11534622B2 (en) 2014-08-18 2022-12-27 Immunolight, Llc Non-invasive systems and methods for selective activation of photoreactive responses
EP3200575A1 (en) * 2014-09-29 2017-08-09 King Abdullah University Of Science And Technology Laser-based agriculture system
US9897448B2 (en) 2014-10-31 2018-02-20 The Charles Stark Draper Laboratory, Inc. Systems and methods for multiple species atom interferometry
US10331087B2 (en) 2014-12-03 2019-06-25 The Charles Stark Draper Laboratory, Inc. Atom interferometry in dynamic environments
US11123366B1 (en) 2014-12-15 2021-09-21 Children's Hospital Of Orange County Methods, materials, and systems for treating injuries to the central nervous system using light emitting nanoparticles
US20190022221A1 (en) 2015-01-14 2019-01-24 Immunolight, Llc. Non-invasive systems and methods for treatment of a host carrying a virus with photoactivatable drugs
WO2017173315A1 (en) 2016-04-01 2017-10-05 Black Light Surgical, Inc. Systems, devices, and methods for time-resolved fluorescent spectroscopy
CA3083789A1 (en) 2017-11-29 2019-06-06 The Rockefeller University Combination of local and systemic therapies for enhanced treatment of dermatologic conditions
EP3773548B1 (en) 2018-05-16 2023-08-09 Provectus Pharmatech, Inc. In vitro and xenograft anti-tumor activity of a halogenated-xanthene against refractory pediatric solid tumors
US11419844B2 (en) 2019-11-19 2022-08-23 Provectus Pharmatech, Inc. Halogenated xanthene composition and method for treating hematologic cancers
US12064507B2 (en) 2019-11-19 2024-08-20 Provectus Pharmatech, Inc. Composition and method for oral treatment of leukemia
US11938182B2 (en) 2020-03-26 2024-03-26 Provectus Pharmatech, Inc. Halogenated xanthenes as vaccine adjuvants
MX2022011765A (es) 2020-03-26 2022-11-09 Provectus Pharmatech Inc Usos novedosos de xantenos halogenados en oncologia y virologia.

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4578079A (en) * 1982-08-04 1986-03-25 La Jolla Cancer Research Foundation Tetrapeptide
US4589881A (en) * 1982-08-04 1986-05-20 La Jolla Cancer Research Foundation Polypeptide
JPS63111886A (ja) * 1986-10-29 1988-05-17 呉羽化学工業株式会社 光ダイオ−ドを用いた癌治療装置
US5053006A (en) * 1988-04-19 1991-10-01 Watson Brant D Method for the permanent occlusion of arteries
US4925736A (en) * 1988-07-06 1990-05-15 Long Island Jewish Medical Center Topical hematoporphyrin
US5654267A (en) * 1988-12-20 1997-08-05 La Jolla Cancer Research Center Cooperative combinations of ligands contained within a matrix
US5498694A (en) * 1989-05-25 1996-03-12 La Jolla Cancer Research Foundation Peptides of the cytoplasmic domain of integrin
US4973848A (en) * 1989-07-28 1990-11-27 J. Mccaughan Laser apparatus for concurrent analysis and treatment
US5121398A (en) * 1989-09-26 1992-06-09 Excel Technology, Inc. Broadly tunable, high repetition rate solid state lasers and uses thereof
US5034613A (en) * 1989-11-14 1991-07-23 Cornell Research Foundation, Inc. Two-photon laser microscopy
EP0505355A4 (en) * 1989-12-11 1992-12-30 Lasb Laser, Corp. Laser therapeutic apparatus and method
US5629291A (en) * 1992-01-31 1997-05-13 La Jolla Cancer Research Foundation Methods of modulating fibronectin extracellular matrix assembly
US5627263A (en) * 1993-11-24 1997-05-06 La Jolla Cancer Research Foundation Integrin-binding peptides
US5558666A (en) * 1994-01-14 1996-09-24 Coherent, Inc. Handpiece for producing highly collimated laser beam for dermatological procedures
US5586981A (en) * 1994-08-25 1996-12-24 Xin-Hua Hu Treatment of cutaneous vascular and pigmented lesions
US5643334A (en) * 1995-02-07 1997-07-01 Esc Medical Systems Ltd. Method and apparatus for the diagnostic and composite pulsed heating and photodynamic therapy treatment
US5576013A (en) * 1995-03-21 1996-11-19 Eastern Virginia Medical School Treating vascular and neoplastic tissues
US5912257A (en) * 1995-09-06 1999-06-15 The Research Foundation Of State University Of New York Two-photon upconverting dyes and applications
US5622699A (en) * 1995-09-11 1997-04-22 La Jolla Cancer Research Foundation Method of identifying molecules that home to a selected organ in vivo
US5759767A (en) * 1996-10-11 1998-06-02 Joseph R. Lakowicz Two-photon and multi-photon measurement of analytes in animal and human tissues and fluids
US5832931A (en) * 1996-10-30 1998-11-10 Photogen, Inc. Method for improved selectivity in photo-activation and detection of molecular diagnostic agents

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111592920A (zh) * 2020-05-21 2020-08-28 新沂百川畅银新能源有限公司 一种沼气脱硫净化工艺

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US5829448A (en) 1998-11-03
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US5998597A (en) 1999-12-07
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NO991492L (no) 1999-05-31
KR20000035893A (ko) 2000-06-26
US6042603A (en) 2000-03-28
CA2252783A1 (en) 1998-05-07
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