CN1264425A - 用于诊断和治疗的呼吸道合胞病毒表位和含有它们的抗体 - Google Patents

用于诊断和治疗的呼吸道合胞病毒表位和含有它们的抗体 Download PDF

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Publication number
CN1264425A
CN1264425A CN98807304A CN98807304A CN1264425A CN 1264425 A CN1264425 A CN 1264425A CN 98807304 A CN98807304 A CN 98807304A CN 98807304 A CN98807304 A CN 98807304A CN 1264425 A CN1264425 A CN 1264425A
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CN
China
Prior art keywords
seq
peptide
rsv
antibody
sequence
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Pending
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CN98807304A
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English (en)
Chinese (zh)
Inventor
T·N·恩谷元
U·泊尔
L·格斯特克
A·贝克
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
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Pierre Fabre Medicament SA
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Application filed by Pierre Fabre Medicament SA filed Critical Pierre Fabre Medicament SA
Publication of CN1264425A publication Critical patent/CN1264425A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/11—Paramyxoviridae (F); Pneumoviridae (F), e.g. respiratory syncytial virus [RSV]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN98807304A 1997-07-17 1998-07-17 用于诊断和治疗的呼吸道合胞病毒表位和含有它们的抗体 Pending CN1264425A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9709079A FR2766192B1 (fr) 1997-07-17 1997-07-17 Epitopes du vrs et anticorps les comportant, utiles dans le diagnostic et la therapie
FR97/09079 1997-07-17

Publications (1)

Publication Number Publication Date
CN1264425A true CN1264425A (zh) 2000-08-23

Family

ID=9509314

Family Applications (1)

Application Number Title Priority Date Filing Date
CN98807304A Pending CN1264425A (zh) 1997-07-17 1998-07-17 用于诊断和治疗的呼吸道合胞病毒表位和含有它们的抗体

Country Status (8)

Country Link
EP (1) EP1003851A2 (fr)
JP (1) JP2001510039A (fr)
CN (1) CN1264425A (fr)
AU (1) AU756110B2 (fr)
BR (1) BR9810907A (fr)
CA (1) CA2296736A1 (fr)
FR (1) FR2766192B1 (fr)
WO (1) WO1999003987A2 (fr)

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100528896C (zh) * 2004-02-03 2009-08-19 中国人民解放军军事医学科学院毒物药物研究所 用于预防、诊断和治疗呼吸道合胞病毒感染的嵌合抗原及其抗体
CN101130765B (zh) * 2006-08-21 2011-04-06 北京阿斯可来生物工程有限公司 呼吸道合胞病毒检测试剂盒
CN102711818A (zh) * 2009-08-04 2012-10-03 美利坚合众国政府疾病控制和预防中心 抗rsv免疫原和免疫方法
CN103163302A (zh) * 2011-12-10 2013-06-19 石家庄恩泽药品技术开发有限公司 一种采用定向交叉偶联技术制备的短肽抗体试剂盒
CN101808663B (zh) * 2007-10-25 2015-09-30 特雷利斯生物科学股份有限公司 抗rsv g蛋白抗体
CN106397547A (zh) * 2016-11-28 2017-02-15 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106432436A (zh) * 2016-11-28 2017-02-22 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106432438A (zh) * 2016-11-28 2017-02-22 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106432439A (zh) * 2016-11-28 2017-02-22 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106432435A (zh) * 2016-11-28 2017-02-22 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106432437A (zh) * 2016-11-28 2017-02-22 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106518988A (zh) * 2016-11-28 2017-03-22 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106749556A (zh) * 2016-11-28 2017-05-31 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106749555A (zh) * 2016-11-28 2017-05-31 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN112409481A (zh) * 2020-12-01 2021-02-26 福州捷赫生物科技有限公司 抗p40蛋白单克隆抗体、细胞系及其制备方法和应用

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2790959B1 (fr) * 1999-03-15 2003-06-27 Pf Medicament Utilisation de fractions membranaires bacteriennes a effet adjuvant, leurs procedes de preparation et composition pharmaceutique les contenant
GB9920000D0 (en) * 1999-08-25 1999-10-27 Imp Cancer Res Tech Polypeptides
FR2798857B1 (fr) * 1999-09-23 2003-06-06 Pf Medicament Utilisation d'une proteine de membrane ompa d'enterobacterie associee a un peptide immunogene du vrs pour la preparation de vaccins administrables par voie nasale
FR2805163A1 (fr) * 2000-02-21 2001-08-24 Pf Medicament Utilisation d'un detergent de type zwittergent pour la preparation d'une composition pharmaceutique destinee a etre administree par voie nasale
EP1174506A1 (fr) * 2000-06-28 2002-01-23 Stichting Dienst Landbouwkundig Onderzoek Le peptide C-terminal de Erns et ses analogues
FR2819810B1 (fr) * 2001-01-23 2004-05-28 Pf Medicament Peptides non glycosyles derives de la proteine g du vrs et leur utilisation dans un vaccin
FR2827605B1 (fr) 2001-07-20 2004-07-16 Pf Medicament Nouveaux peptides derives de la proteine g du vrs et leur utilisation dans un vaccin
WO2003066676A1 (fr) * 2002-02-05 2003-08-14 Geymonat S.P.A. Procede de production d'un facteur de croissance placentaire recombinant
EP1768993A4 (fr) * 2004-06-16 2008-07-23 Univ Johns Hopkins Region riche en cysteine du virus respiratoire syncytial et procedes d'utilisation associes

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223254A (en) * 1987-09-29 1993-06-29 Praxis Biologics, Inc. Respiratory syncytial virus: vaccines
SE9101433D0 (sv) * 1991-05-13 1991-05-13 Marianne Hansson Recombinant dna sequence and its use
FR2718452B1 (fr) * 1994-04-06 1996-06-28 Pf Medicament Elément d'immunogène, agent immunogène, composition pharmaceutique et procédé de préparation.
EP0777685B1 (fr) * 1994-08-25 1999-04-14 Stichting Instituut voor Dierhouderij en Diergezondheid Peptides antigeniques derives de la proteine g du virus respiratoire syncytial (rsv) utilises pour le diagnostic specifique d'un type ou d'un sous-type d'une infection a rsv
FR2726472B1 (fr) * 1994-11-07 1997-01-31 Pf Medicament Proteine porteuse a effet adjuvant, complexe immunogene la contenant, leur procede de preparation, sequence nucleotidique et vaccin
FR2726471B1 (fr) * 1994-11-07 1997-01-31 Pf Medicament Procede pour ameliorer l'immunogenicite d'un compose immunogene ou d'un haptene et application a la preparation de vaccins
FR2726577B1 (fr) * 1994-11-07 1997-01-31 Pf Medicament Procede d'obtention d'un peptide derive du virus respiratoire syncitial, polypeptide et bacterie l'exprimant, et leurs applications a titre de medicament
FR2726576B1 (fr) * 1994-11-07 1997-01-31 Pf Medicament Production de peptides analogues de peptides hydrophobes, peptide recombinant, sequence d'adn correspondante
AUPO026596A0 (en) * 1996-06-05 1996-06-27 Biomolecular Research Institute Limited Viral peptide

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100528896C (zh) * 2004-02-03 2009-08-19 中国人民解放军军事医学科学院毒物药物研究所 用于预防、诊断和治疗呼吸道合胞病毒感染的嵌合抗原及其抗体
CN101130765B (zh) * 2006-08-21 2011-04-06 北京阿斯可来生物工程有限公司 呼吸道合胞病毒检测试剂盒
CN101808663B (zh) * 2007-10-25 2015-09-30 特雷利斯生物科学股份有限公司 抗rsv g蛋白抗体
CN102711818A (zh) * 2009-08-04 2012-10-03 美利坚合众国政府疾病控制和预防中心 抗rsv免疫原和免疫方法
CN102711818B (zh) * 2009-08-04 2014-09-24 美利坚合众国政府疾病控制和预防中心,健康和公共事业部 抗rsv免疫原和免疫方法
CN103163302A (zh) * 2011-12-10 2013-06-19 石家庄恩泽药品技术开发有限公司 一种采用定向交叉偶联技术制备的短肽抗体试剂盒
CN103163302B (zh) * 2011-12-10 2015-06-03 河北菲尼斯生物技术有限公司 一种采用定向交叉偶联技术制备的短肽抗体试剂盒
CN106432436A (zh) * 2016-11-28 2017-02-22 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106397547A (zh) * 2016-11-28 2017-02-15 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106432438A (zh) * 2016-11-28 2017-02-22 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106432439A (zh) * 2016-11-28 2017-02-22 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106432435A (zh) * 2016-11-28 2017-02-22 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106432437A (zh) * 2016-11-28 2017-02-22 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106518988A (zh) * 2016-11-28 2017-03-22 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106749556A (zh) * 2016-11-28 2017-05-31 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN106749555A (zh) * 2016-11-28 2017-05-31 烟台偌帝生物工程有限公司 一种牛呼吸道胞合体病毒抗原蛋白
CN112409481A (zh) * 2020-12-01 2021-02-26 福州捷赫生物科技有限公司 抗p40蛋白单克隆抗体、细胞系及其制备方法和应用
CN112409481B (zh) * 2020-12-01 2024-03-26 福州捷赫生物科技有限公司 抗p40蛋白单克隆抗体、细胞系及其制备方法和应用

Also Published As

Publication number Publication date
FR2766192A1 (fr) 1999-01-22
EP1003851A2 (fr) 2000-05-31
CA2296736A1 (fr) 1999-01-28
AU756110B2 (en) 2003-01-02
FR2766192B1 (fr) 2001-07-13
AU8812398A (en) 1999-02-10
WO1999003987A2 (fr) 1999-01-28
JP2001510039A (ja) 2001-07-31
WO1999003987A3 (fr) 1999-04-08
BR9810907A (pt) 2000-08-01

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