CN1283106A - 含有具有亲脂性糖皮质甾类和唯一一种表面活性剂的胶束的药物组合物 - Google Patents

含有具有亲脂性糖皮质甾类和唯一一种表面活性剂的胶束的药物组合物 Download PDF

Info

Publication number
CN1283106A
CN1283106A CN98812507A CN98812507A CN1283106A CN 1283106 A CN1283106 A CN 1283106A CN 98812507 A CN98812507 A CN 98812507A CN 98812507 A CN98812507 A CN 98812507A CN 1283106 A CN1283106 A CN 1283106A
Authority
CN
China
Prior art keywords
composition
glucocorticosteroid
surfactant
micelles
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN98812507A
Other languages
English (en)
Chinese (zh)
Inventor
G·舍奎斯特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of CN1283106A publication Critical patent/CN1283106A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Dispersion Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN98812507A 1997-12-22 1998-12-22 含有具有亲脂性糖皮质甾类和唯一一种表面活性剂的胶束的药物组合物 Pending CN1283106A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9704833A SE9704833D0 (sv) 1997-12-22 1997-12-22 New formulation
SE97048334 1997-12-22

Publications (1)

Publication Number Publication Date
CN1283106A true CN1283106A (zh) 2001-02-07

Family

ID=20409536

Family Applications (1)

Application Number Title Priority Date Filing Date
CN98812507A Pending CN1283106A (zh) 1997-12-22 1998-12-22 含有具有亲脂性糖皮质甾类和唯一一种表面活性剂的胶束的药物组合物

Country Status (20)

Country Link
EP (1) EP1043973A1 (id)
JP (1) JP2001526210A (id)
KR (1) KR20010024789A (id)
CN (1) CN1283106A (id)
AR (1) AR017220A1 (id)
AU (1) AU1993599A (id)
BR (1) BR9813811A (id)
CA (1) CA2315782A1 (id)
EE (1) EE200000388A (id)
HU (1) HUP0102365A3 (id)
ID (1) ID26945A (id)
IL (1) IL136880A0 (id)
NO (1) NO20003220L (id)
NZ (1) NZ505073A (id)
PL (1) PL341361A1 (id)
SE (1) SE9704833D0 (id)
SK (1) SK9532000A3 (id)
TR (1) TR200001977T2 (id)
WO (1) WO1999032089A1 (id)
ZA (1) ZA9811461B (id)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100579510C (zh) * 2006-04-13 2010-01-13 新疆维吾尔自治区包虫病临床研究所 新型前体胶束制剂及其生产方法
CN101982168A (zh) * 2010-11-02 2011-03-02 山东大学 一种槲皮素纳米胶束制剂及其制备方法
CN102793678A (zh) * 2011-05-26 2012-11-28 邓世明 一种不含吐温的多烯紫杉醇注射剂的制备方法

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9902674D0 (sv) * 1999-07-12 1999-07-12 Astra Ab New composition
SE0000332D0 (sv) * 2000-01-31 2000-01-31 Astrazeneca Ab New use
GB0019172D0 (en) 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
US6858596B2 (en) 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
US6777399B2 (en) 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6777400B2 (en) 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6858593B2 (en) 2000-08-05 2005-02-22 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6759398B2 (en) 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
EP2067784A3 (en) 2000-08-05 2012-08-22 Glaxo Group Limited 17.beta.-carbothioate 17.alpha.-arylcarbonyloxyloxy androstane derivatives as anti-inflammatory agents
US6787532B2 (en) * 2000-08-05 2004-09-07 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivatives
US6750210B2 (en) 2000-08-05 2004-06-15 Smithkline Beecham Corporation Formulation containing novel anti-inflammatory androstane derivative
SE0100901D0 (sv) * 2001-03-15 2001-03-15 Astrazeneca Ab New composition
UA77656C2 (en) 2001-04-07 2007-01-15 Glaxo Group Ltd S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent
WO2002088167A1 (en) 2001-04-30 2002-11-07 Glaxo Group Limited Anti-inflammatory 17.beta.-carbothioate ester derivatives of androstane with a cyclic ester group in position 17.alpha
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
EP1661556A4 (en) * 2003-08-20 2010-05-19 Ajinomoto Kk MEDICAL PREPARATION WITH IMPROVED RESOLUTION CHARACTERISTICS
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
US9050368B2 (en) 2007-11-13 2015-06-09 Meritage Pharma, Inc. Corticosteroid compositions
HUE038452T2 (hu) 2007-11-13 2018-10-29 Meritage Pharma Inc Gyomor és bélrendszeri gyulladások kezelésére szolgáló kompozíciók
BRPI0918253A2 (pt) * 2008-09-12 2015-12-15 Critical Pharmaceuticals Ltd aperfeicoamento na absorcao de agentes terapeuticos atraves das membranas mucosas ou da pele
DE102011108948A1 (de) * 2011-07-29 2013-01-31 Achim Göpferich Wässrige, kolloidale Lösungen von lipophilen Substanzen,insbesondere Arzneistofflösungen
JP5456802B2 (ja) * 2012-01-23 2014-04-02 株式会社Ｃａｃ 細胞遊走促進剤及び創傷治療用の経皮吸収剤
EP3021844B1 (en) * 2013-07-17 2019-11-13 Council of Scientific & Industrial Research Pharmaceutical composition for the treatment of diminution of bone tissue
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
US9931349B2 (en) 2016-04-01 2018-04-03 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
KR102086316B1 (ko) * 2019-09-09 2020-03-09 한국콜마주식회사 경피흡수성이 우수한 화장료 조성물

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0179583A1 (en) * 1984-10-04 1986-04-30 Merck & Co. Inc. A system for enhancing the water dissolution rate and solubility of poorly soluble drugs
US4994439A (en) * 1989-01-19 1991-02-19 California Biotechnology Inc. Transmembrane formulations for drug administration
SA95160463B1 (ar) * 1994-12-22 2005-10-04 استرا أكتيبولاج مساحيق للاستنشاق

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100579510C (zh) * 2006-04-13 2010-01-13 新疆维吾尔自治区包虫病临床研究所 新型前体胶束制剂及其生产方法
CN101982168A (zh) * 2010-11-02 2011-03-02 山东大学 一种槲皮素纳米胶束制剂及其制备方法
CN102793678A (zh) * 2011-05-26 2012-11-28 邓世明 一种不含吐温的多烯紫杉醇注射剂的制备方法
CN102793678B (zh) * 2011-05-26 2017-06-30 邓世明 一种不含吐温的多烯紫杉醇注射剂的制备方法

Also Published As

Publication number Publication date
IL136880A0 (en) 2001-06-14
HUP0102365A3 (en) 2002-01-28
BR9813811A (pt) 2000-10-03
ID26945A (id) 2001-02-22
NO20003220L (no) 2000-08-22
CA2315782A1 (en) 1999-07-01
ZA9811461B (en) 1999-06-22
NO20003220D0 (no) 2000-06-21
NZ505073A (en) 2002-09-27
AU1993599A (en) 1999-07-12
SE9704833D0 (sv) 1997-12-22
JP2001526210A (ja) 2001-12-18
WO1999032089A1 (en) 1999-07-01
EE200000388A (et) 2002-02-15
KR20010024789A (ko) 2001-03-26
HUP0102365A2 (hu) 2001-11-28
EP1043973A1 (en) 2000-10-18
PL341361A1 (en) 2001-04-09
SK9532000A3 (en) 2000-11-07
AR017220A1 (es) 2001-08-22
TR200001977T2 (tr) 2000-12-21

Similar Documents

Publication Publication Date Title
WO1999032089A1 (en) Pharmaceutical compositions comprising micelles comprising lipophilic glucocorticosteroid and only one surfactant
JP6966981B2 (ja) ステロイドの抗痙攣活性
US8455002B2 (en) Stable corticosteroid nanoparticulate formulations and methods for the making and use thereof
JP4875239B2 (ja) 鼻および肺送達のためのコルチコステロイドを含有する水性組成物
CN1187044C (zh) 可储存的含福莫特罗的活性物质浓缩液
CN103269687B (zh) 贝托斯汀组合物
CN102319209B (zh) 鼻用药物制剂和使用方法
JP5001657B2 (ja) 噴霧化用のシクレソニドの水性懸濁液
CN1805729B (zh) 鼻用药物制剂和使用方法
US20120022032A1 (en) Corticosteroid compositions and methods of treatments thereof
CN114007588A (zh) 比拉斯汀的稳定和保存的药物组合物
US20260076958A1 (en) Liquid formulations of indacaterol
ES3037198T3 (en) Combination therapy for inhalation administration
CN101757625A (zh) 环糊精包合皮质激素和h1受体拮抗剂的鼻用药物组合物
WO2024206662A1 (en) Liquid formulations of indacaterol and glycopyrronium
EP3897577A1 (en) Intranasal formulation
WO2023192445A1 (en) Liquid formulations of indacaterol and glycopyrronium
WO2015009776A1 (en) Low dose corticosteroid microemulsion compositions and methods of treatments thereof
TWI924704B (zh) 茚達特羅(indacaterol)之液體調配物
MXPA00006161A (en) Pharmaceutical compositions comprising micelles comprising lipophilic glucocorticosteroid and only one surfactant
CZ20002298A3 (cs) Farmaceutický prostředek, obsahující micely ve vodném prostředí, a způsob jeho přípravy
HK1091730A (en) Nasal pharmaceutical formulations and methods of using the same
WO2018069830A1 (en) Pharmaceutical composition for the treatment of sinusitis and COPD

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication