CN1348498A - 新的核酸转移试剂、含有它们的组合物及其应用 - Google Patents

新的核酸转移试剂、含有它们的组合物及其应用 Download PDF

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Publication number
CN1348498A
CN1348498A CN99813646A CN99813646A CN1348498A CN 1348498 A CN1348498 A CN 1348498A CN 99813646 A CN99813646 A CN 99813646A CN 99813646 A CN99813646 A CN 99813646A CN 1348498 A CN1348498 A CN 1348498A
Authority
CN
China
Prior art keywords
nucleic acid
transfering reagent
amino
composition
sugar
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN99813646A
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English (en)
Chinese (zh)
Inventor
J·赫斯科维丝
H·霍夫兰德
C·杰科宾
D·谢尔曼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9815309A external-priority patent/FR2786700B1/fr
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Publication of CN1348498A publication Critical patent/CN1348498A/zh
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
CN99813646A 1998-12-03 1999-12-02 新的核酸转移试剂、含有它们的组合物及其应用 Pending CN1348498A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR98/15309 1998-12-03
FR9815309A FR2786700B1 (fr) 1998-12-03 1998-12-03 Nouveaux agents de transfert d'acides nucleiques, compositions les contenant et leurs utilisations
US11718499P 1999-01-26 1999-01-26
US60/117,184 1999-01-26

Publications (1)

Publication Number Publication Date
CN1348498A true CN1348498A (zh) 2002-05-08

Family

ID=26234691

Family Applications (1)

Application Number Title Priority Date Filing Date
CN99813646A Pending CN1348498A (zh) 1998-12-03 1999-12-02 新的核酸转移试剂、含有它们的组合物及其应用

Country Status (13)

Country Link
EP (1) EP1137793A2 (cs)
JP (1) JP2002531468A (cs)
KR (1) KR20010101116A (cs)
CN (1) CN1348498A (cs)
AU (1) AU772033B2 (cs)
BR (1) BR9915897A (cs)
CA (1) CA2353576A1 (cs)
CZ (1) CZ20011909A3 (cs)
HU (1) HUP0200345A3 (cs)
IL (1) IL142704A0 (cs)
NO (1) NO20012684L (cs)
PL (1) PL348513A1 (cs)
WO (1) WO2000032803A2 (cs)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103820320A (zh) * 2013-06-25 2014-05-28 宁波有成生物医药科技有限公司 一种非冻型rna保护液

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2805271B1 (fr) * 2000-02-18 2002-04-26 Aventis Pharma Sa Procede de preparation de polyalkylenimines fonctionnalises, compositions les contenant et leurs utilisations
JP2005080598A (ja) * 2003-09-10 2005-03-31 Japan Science & Technology Agency β−1,3−グルカン誘導体を用いるプラスミドDNAの導入法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4690596A (en) * 1994-12-30 1996-07-24 Chiron Viagene, Inc. Nucleic acid condensing agents with reduced immunogenicity
FR2730637B1 (fr) * 1995-02-17 1997-03-28 Rhone Poulenc Rorer Sa Composition pharmaceutique contenant des acides nucleiques, et ses utilisations
US5948681A (en) * 1996-08-14 1999-09-07 Children's Hospital Of Philadelphia Non-viral vehicles for use in gene transfer

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103820320A (zh) * 2013-06-25 2014-05-28 宁波有成生物医药科技有限公司 一种非冻型rna保护液

Also Published As

Publication number Publication date
HUP0200345A2 (hu) 2002-05-29
IL142704A0 (en) 2002-03-10
AU1564600A (en) 2000-06-19
NO20012684L (no) 2001-07-30
HUP0200345A3 (en) 2003-12-29
JP2002531468A (ja) 2002-09-24
AU772033B2 (en) 2004-04-08
CZ20011909A3 (cs) 2001-09-12
WO2000032803A2 (fr) 2000-06-08
PL348513A1 (en) 2002-06-03
CA2353576A1 (fr) 2000-06-08
EP1137793A2 (fr) 2001-10-04
KR20010101116A (ko) 2001-11-14
BR9915897A (pt) 2001-08-21
NO20012684D0 (no) 2001-05-31
WO2000032803A3 (fr) 2000-10-12

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WD01 Invention patent application deemed withdrawn after publication