CN1394602A - 用于治疗动脉粥样硬化的苯甲酸取代的苯并吡喃 - Google Patents

用于治疗动脉粥样硬化的苯甲酸取代的苯并吡喃 Download PDF

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Publication number
CN1394602A
CN1394602A CN02125125A CN02125125A CN1394602A CN 1394602 A CN1394602 A CN 1394602A CN 02125125 A CN02125125 A CN 02125125A CN 02125125 A CN02125125 A CN 02125125A CN 1394602 A CN1394602 A CN 1394602A
Authority
CN
China
Prior art keywords
treating atherosclerosis
compound
benzyl
carboxy
mammal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN02125125A
Other languages
English (en)
Chinese (zh)
Inventor
罗伯特·J·艾洛
帕特里夏－安·布拉萨
萨拉林·林赛
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Products Inc
Original Assignee
Pfizer Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc filed Critical Pfizer Products Inc
Publication of CN1394602A publication Critical patent/CN1394602A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN02125125A 2001-06-28 2002-06-28 用于治疗动脉粥样硬化的苯甲酸取代的苯并吡喃 Pending CN1394602A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US30171201P 2001-06-28 2001-06-28
US60/301,712 2001-06-28
US32825401P 2001-10-10 2001-10-10
US60/328,254 2001-10-10

Publications (1)

Publication Number Publication Date
CN1394602A true CN1394602A (zh) 2003-02-05

Family

ID=26972559

Family Applications (1)

Application Number Title Priority Date Filing Date
CN02125125A Pending CN1394602A (zh) 2001-06-28 2002-06-28 用于治疗动脉粥样硬化的苯甲酸取代的苯并吡喃

Country Status (12)

Country Link
EP (1) EP1270000A3 (2)
JP (1) JP2003034638A (2)
KR (1) KR20030015828A (2)
CN (1) CN1394602A (2)
AU (1) AU4239302A (2)
CA (1) CA2391205A1 (2)
CZ (1) CZ20022076A3 (2)
HK (1) HK1049795A1 (2)
HU (1) HUP0202114A3 (2)
IL (1) IL150340A0 (2)
PL (1) PL354770A1 (2)
SK (1) SK8682002A3 (2)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4476934B2 (ja) * 2003-04-14 2010-06-09 明治乳業株式会社 新規ペプチドおよび免疫賦活剤、機能性食品ならびに機能性食品の製造方法
CA2574627A1 (en) * 2004-07-22 2006-02-02 Pharmacia Corporation Compositions for treatment of inflammation and pain using a combination of a cox-2 selective inhibitor and a ltb4 receptor antagonist
PL1888033T3 (pl) * 2005-06-09 2014-09-30 Meda Ab Sposób i kompozycja do leczenia chorób zapalnych
EP3383388B1 (en) 2015-11-30 2021-04-14 Merck Sharp & Dohme Corp. Aryl acylsulfonamides as blt1 antagonists
US10370368B2 (en) 2015-11-30 2019-08-06 Merck Sharp & Dohme Corp. Aryl acylsulfonamides as BLT1 antagonists

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3720493A1 (de) * 1987-06-20 1989-01-26 Nattermann A & Cie Arzneizubereitungen mit mikronisierten ebselen-kristallen
MX9300312A (es) * 1992-01-23 1993-07-31 Pfizer Antagonistas benzopiranicos y relacionado de ltb.
DE4228200A1 (de) * 1992-08-25 1994-03-03 Schering Ag Neue Pyridin-Derivate mit Leukotrien-B¶4¶-antagonistischer Wirkung
AU696890B2 (en) * 1994-10-13 1998-09-24 Pfizer Inc. Benzopyran and benzo-fused compounds, their preparation and their use as leukotriene B4 (LTB4) antagonists
MX9702734A (es) * 1994-10-13 1997-06-28 Pfizer Benzopirano y compuestos benzocondensados, su preparacion y su uso como antagonistas de leucotrieno b4 (ltb4).
EP0833664A1 (en) * 1995-06-12 1998-04-08 G.D. SEARLE & CO. Combination of a cyclooxygenase-2 inhibitor and a leukotriene b 4? receptor antagonist for the treatment of inflammations
DE19636689A1 (de) * 1996-09-10 1998-03-12 Boehringer Ingelheim Kg Neue Benzamidinderivate
TR199900592T2 (xx) * 1996-09-16 1999-06-21 Pfizer Inc. Kromanol t�revlerinin haz�rland��� i�lem ve ara ba�lar
EP0963755A3 (en) * 1998-04-16 2001-03-14 Pfizer Products Inc. Use of benzopyranes for preventing allograft rejection
WO2000010552A2 (en) * 1998-08-24 2000-03-02 Global Vascular Concepts, Inc. Use of anti-angiogenic agents for inhibiting vessel wall injury
JP2003225088A (ja) * 1999-09-10 2003-08-12 Meiji Seika Kaisha Ltd ヒト・ロイコトリエンｂ４第二受容体及びそれをコードするｄｎａ
AU3930201A (en) * 2000-03-17 2001-09-24 Bayer Aktiengesellschaft Regulation of human leukotriene B4-like G protein-coupled receptor

Also Published As

Publication number Publication date
HU0202114D0 (2) 2002-09-28
KR20030015828A (ko) 2003-02-25
EP1270000A3 (en) 2003-02-12
HUP0202114A2 (hu) 2003-01-28
HK1049795A1 (zh) 2003-05-30
CA2391205A1 (en) 2002-12-28
HUP0202114A3 (en) 2004-07-28
AU4239302A (en) 2003-01-02
EP1270000A2 (en) 2003-01-02
JP2003034638A (ja) 2003-02-07
PL354770A1 (en) 2002-12-30
CZ20022076A3 (cs) 2004-05-12
IL150340A0 (en) 2002-12-01
SK8682002A3 (en) 2004-08-03

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