CN1440407A - 新的bispidine化合物及其在治疗心律失常中的应用 - Google Patents

新的bispidine化合物及其在治疗心律失常中的应用 Download PDF

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Publication number
CN1440407A
CN1440407A CN01812475A CN01812475A CN1440407A CN 1440407 A CN1440407 A CN 1440407A CN 01812475 A CN01812475 A CN 01812475A CN 01812475 A CN01812475 A CN 01812475A CN 1440407 A CN1440407 A CN 1440407A
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CN
China
Prior art keywords
compound
formula
alkyl
het
optionally substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN01812475A
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English (en)
Chinese (zh)
Inventor
K·安德松
A·比约尔雷
M·比约尔斯尼
F·庞滕
G·斯特兰德伦德
P·斯文松
L·托蒂
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE0002603A external-priority patent/SE0002603D0/xx
Priority claimed from SE0002788A external-priority patent/SE0002788D0/xx
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of CN1440407A publication Critical patent/CN1440407A/zh
Pending legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN01812475A 2000-07-07 2001-07-04 新的bispidine化合物及其在治疗心律失常中的应用 Pending CN1440407A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE00026039 2000-07-07
SE0002603A SE0002603D0 (sv) 2000-07-07 2000-07-07 New compounds
SE00027888 2000-07-27
SE0002788A SE0002788D0 (sv) 2000-07-27 2000-07-27 New compounds

Publications (1)

Publication Number Publication Date
CN1440407A true CN1440407A (zh) 2003-09-03

Family

ID=26655177

Family Applications (1)

Application Number Title Priority Date Filing Date
CN01812475A Pending CN1440407A (zh) 2000-07-07 2001-07-04 新的bispidine化合物及其在治疗心律失常中的应用

Country Status (20)

Country Link
EP (1) EP1301510A1 (is)
JP (1) JP2004502772A (is)
KR (1) KR20030014426A (is)
CN (1) CN1440407A (is)
AR (1) AR030302A1 (is)
AU (1) AU2001271161A1 (is)
BR (1) BR0112267A (is)
CA (1) CA2412848A1 (is)
CZ (1) CZ200332A3 (is)
EE (1) EE200300013A (is)
HU (1) HUP0301304A2 (is)
IL (1) IL153485A0 (is)
IS (1) IS6660A (is)
MX (1) MXPA02012942A (is)
NO (1) NO20030057L (is)
NZ (1) NZ523540A (is)
PL (1) PL360474A1 (is)
RU (1) RU2002134450A (is)
SK (1) SK42003A3 (is)
WO (1) WO2002004446A1 (is)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004103991A1 (en) * 2003-05-20 2004-12-02 'chemical Diversity Research Institute', Ltd. 2-substituted piperidines, focused library and a pharmaceutical compound
US7399765B2 (en) 2003-09-19 2008-07-15 Abbott Laboratories Substituted diazabicycloalkane derivatives
SE0302775D0 (sv) * 2003-10-20 2003-10-20 Astrazeneca Ab Chemical compound and assay
RU2472793C1 (ru) * 2011-07-20 2013-01-20 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Московский государственный университет тонких химических технологий имени М.В. Ломоносова" (МИТХТ им.М.В.Ломоносова) 1,5-бис[(трет-бутиламино)метил]-n,n'-ди-трет-бутилбиспидин-9-она и способ его получения
CN116444556A (zh) * 2023-03-24 2023-07-18 苏州威迈芯材半导体有限公司 一种有机硅中间体4-苯甲腈基氧烷基三烷氧基硅烷的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3732094A1 (de) * 1987-09-24 1989-04-06 Basf Ag Bispidinderivate als klasse iii-antiarrhythmika
US5110933A (en) * 1989-11-13 1992-05-05 Board Of Regents Of Oklahoma State University Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof
US5468858A (en) * 1993-10-28 1995-11-21 The Board Of Regents Of Oklahoma State University Physical Sciences N-alkyl and n-acyl derivatives of 3,7-diazabicyclo-[3.3.1]nonanes and selected salts thereof as multi-class antiarrhythmic agents
DE4402931A1 (de) * 1994-02-01 1995-08-03 Kali Chemie Pharma Gmbh Neue 3-Phenylsulfonyl-3,7-diazabicyclo[3,3,1] nonan-Verbindungen enthaltende Arzneimittel
DE4402933A1 (de) * 1994-02-01 1995-08-03 Kali Chemie Pharma Gmbh Neue 3-Benzoyl-3,7-diazabicyclo[3,3,1] nonan-Verbindungen enthaltende Arzneimittel
SE9704709D0 (sv) * 1997-12-17 1997-12-17 Astra Ab Pharmaceutically active compounds
SE9902269D0 (sv) * 1999-06-16 1999-06-16 Astra Ab Pharmaceutically active compounds
SE9902271D0 (sv) * 1999-06-16 1999-06-16 Astra Ab Pharmaceutically active compounds
SE9902268D0 (sv) * 1999-06-16 1999-06-16 Astra Ab Pharmaceutically active compounds
SE9902270D0 (sv) * 1999-06-16 1999-06-16 Astra Ab Pharmaceutically active compounds

Also Published As

Publication number Publication date
SK42003A3 (en) 2003-07-01
HUP0301304A2 (hu) 2003-08-28
PL360474A1 (en) 2004-09-06
WO2002004446A1 (en) 2002-01-17
NO20030057D0 (no) 2003-01-06
AU2001271161A1 (en) 2002-01-21
CA2412848A1 (en) 2002-01-17
BR0112267A (pt) 2003-05-20
AR030302A1 (es) 2003-08-20
RU2002134450A (ru) 2004-07-10
CZ200332A3 (cs) 2003-04-16
EP1301510A1 (en) 2003-04-16
MXPA02012942A (es) 2003-10-06
NO20030057L (no) 2003-01-31
EE200300013A (et) 2004-10-15
NZ523540A (en) 2004-07-30
KR20030014426A (ko) 2003-02-17
IS6660A (is) 2002-12-19
JP2004502772A (ja) 2004-01-29
IL153485A0 (en) 2003-07-06

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WD01 Invention patent application deemed withdrawn after publication