CN1611232A - Medicinal composition with main effect of antifatigue, radioresistance and melancholia-resistance and its preparing method - Google Patents
Medicinal composition with main effect of antifatigue, radioresistance and melancholia-resistance and its preparing method Download PDFInfo
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Abstract
The present invention relates to a Chinese medicine composition which is made up by utilizing the Chinese medicinal materials of ginseng, licorice root, acanthopanax root, bighead atractylodes rhizome, poria and sehisandra fruit as raw material and adopting the following processes: respectively using ethyl alcohol solution and water to make decoction and extraction of the above-mentioned raw materials, concentrating and drying, etc. Said invented Chinese medicine composition has the main functions of resisting fatigue, resisting radiation and reasisting melanchelia, etc and can be used for improving and curing the diseases of network syndrome, chronic apocamnosis and office syndrome, etc. Said medicine composition has not toxic side effect, and can be made into nutrient agent and health-care food also.
Description
Technical field
The present invention relates to a kind of is the pharmaceutical composition that main effect is used to improve network syndrome, office's syndrome, the various symptoms of chronic fatigue syndrome with resisting fatigue, radioprotective, anti-melancholy, and it can be used as medicine and the health food nutrient uses.
The invention still further relates to a kind of is the preparation of drug combination method that main effect is used to improve network syndrome, office's syndrome, the various symptoms of chronic fatigue syndrome with resisting fatigue, radioprotective, anti-melancholy.
Technical background
Symptoms such as at the beginning of calendar year 2001, a research report of Univ. of Pittsburgh discloses, and the whole world has 1,140 ten thousand people to suffer from various degree network syndrome among the netizen more than 200,000,000, mainly show as inappetence, visual deterioration, anxiety melancholy and headache, and is weak.The struggle for existence of modern society's fierceness and operating pressure are among a kind of state of anxiety people for a long time, and the chronic fatigue syndrome that this mental pressure brings and office's syndrome are with network syndrome and be called " modern civilization disease ".Globalization and the rhythm of life universal, network that particularly are accompanied by computer are constantly accelerated, the crowd who suffers from this network syndrome, chronic fatigue syndrome and office's syndrome sharply increases, and the product that can improve this sub-health state that present stage produces both at home and abroad seldom, and function is limited, be difficult to reach comprehensive and improve " modern civilization disease ", be difficult to take precautions against this sub-health state and transform to disease to the various discomforts that people bring.The bata-carotene of producing with the U.S. Amway Company that has put on market at present is an example, and it is the supplement of body vitamin A, and its main effect is to improve the fatigue of eyes, and other symptom that alleviates the modern civilization disease is not then had much effects.Chinese medicine is historical of long standing and well established as the human body analeptic, it is also a lot of to be used for antifatigue modern Chinese medicine health product, but is a new problem but how to be used to improve and prevent the medicine of network syndrome, chronic fatigue syndrome and office's syndrome and nutrient in conjunction with the targeted exploitation of modern pharmacology.
Summary of the invention
Go up improving the growing demand of the sick various symptoms of modern civilization in order to satisfy society, in order to overcome the vacancy of existing technical deficiency and product, the object of the present invention is to provide a kind of is the medicament and the nutrient of the plant amedica of the main effect pharmaceutical composition, particularly dietotherapeutic that are used to improve network syndrome, chronic fatigue syndrome and the various symptoms of office's syndrome with resisting fatigue, radioprotective, anti-melancholy.
This is the pharmaceutical composition of raw material with the dietotherapeutic, nontoxic (pair) effect, the medicine that can be used as this classes such as improving network syndrome " modern civilization disease " is taken for a long time, can also be used for improving the health state as health food and nutrient, defying age and enhancing body immunity.
The solution of pharmaceutical composition of the present invention, be Chinese medicine about the reason of " melancholia " and " tonifying recipes ", method, side, medicine basis on, about resisting fatigue, radioprotective, the anti-melancholy treatment mechanism that reaches the functional dyspepsia of depression and confirmed fatigue association, develop a kind of pure plant nutrient agent (medicine) that comes out in conjunction with modern medicine, pharmacology with improvement and treatment network syndrome, chronic fatigue syndrome and the various symptoms of office's syndrome.Be characterized in improving comprehensively and nursing one's health the various symptoms of above-mentioned three kinds " modern civilization diseases ", its curative effect is obvious relatively, and safe and reliable, and people can take the purpose that reaches body building for a long time.
It is that main effect is used for improving and treatment network syndrome, chronic fatigue syndrome and the various symptom preparation of drug combination of office's syndrome method with resisting fatigue, radioprotective, anti-melancholy that another object of the present invention provides above-mentioned.
In order to finish purpose of the present invention, the special following technical proposal that proposes of the present invention.
In first embodiment of the present invention, The present invention be more particularly directed to a kind of is that main effect is used for the pharmaceutical composition of " modern civilization diseases " such as improvement and treatment network syndromes with resisting fatigue, radioprotective, anti-melancholy, and it comprises: Radix Ginseng, Radix Glycyrrhizae and Radix Et Caulis Acanthopanacis Senticosi; It is characterized in that the medicament (nutrient) made by the following weight proportion raw material: Radix Ginseng 9～45 weight portions, Radix Glycyrrhizae 4～30 weight portions, Radix Et Caulis Acanthopanacis Senticosi 9～60 weight portions
This medicine is preferably the medicament of being made by the following weight proportion raw material: Radix Ginseng 18～36 weight portions, Radix Glycyrrhizae 8～27 weight portions, Radix Et Caulis Acanthopanacis Senticosi 18～50 weight portions
The medicament that described pharmaceutical composition is preferably made by following weight proportioning raw material: Radix Ginseng 27 weight portions, Radix Glycyrrhizae 18 weight portions, Radix Et Caulis Acanthopanacis Senticosi 45 weight portions
In the scheme of second enforcement of the present invention, of the present invention a kind of be that main effect is used for improving and the pharmaceutical composition of treatment network syndrome etc. " modern civilization diseases " with resisting fatigue, radioprotective, anti-melancholy, also can add 9～45 weight portion Rhizoma Atractylodis Macrocephalaes, 9～45 weight portion Poria, strengthen pharmaceutical composition improvement of the present invention and treatment functional dyspepsia (inappetence) since using because of " modern civilization disease " associations such as network syndrome, chronic fatigue syndrome and office's syndromes.
In the scheme of the 3rd enforcement of the present invention, of the present invention a kind of be that main effect is used for improving and the pharmaceutical composition of treatment network syndrome etc. " modern civilization diseases " with resisting fatigue, radioprotective, anti-melancholy, also can add 3～27 weight portion Fructus Schisandrae Chinensis, with since strengthen pharmaceutical composition resisting fatigue of the present invention, radiation-resistant function, particularly being used for nourishing the liver to improve visual acuity eliminates or alleviates eyestrain state, and can further improve people's intellectual activity, improve mental work usefulness.
Contain acceptable carrier or additive on the materia medica in the pharmaceutical composition of the present invention, and described medicament is said dosage form on any pharmaceutics, is preferably capsule or tablet.
The invention still further relates to a kind of is that main effect is used for the drug extract of " modern civilization diseases " such as improvement and treatment network syndromes with resisting fatigue, radioprotective, anti-melancholy, and this extract adopts following method to obtain:
1, with 9～45 weight portion Radix Ginsengs with alcoholic solution or flooding, through the chromatography purification, drying, the extract of winning;
2, with 4～30 weight portion Radix Glycyrrhizaes, 9～60 weight portion Radix Et Caulis Acanthopanacis Senticosis with alcoholic solution or flooding, filtration, concentrate, dry, second extract;
3, second extract that first extract, the step 2 that step 1 is obtained obtains mixes to be pulverized, and sieves, and gets extract of the present invention.
Be preferably 18～36 weight portion Radix Ginsengs, 8～27 weight portion Radix Glycyrrhizaes, 18～50 weight portion Radix Et Caulis Acanthopanacis Senticosis in above-mentioned method, the best is preferably 27 weight portion Radix Ginsengs, 18 weight portion Radix Glycyrrhizaes, 45 weight portion Radix Et Caulis Acanthopanacis Senticosis.
In said method, can add 9～45 weight portion Rhizoma Atractylodis Macrocephalaes, 9～45 weight portion Poria water or alcoholic acid extract again.
In said method, can add 3～27 weight portion Fructus Schisandrae Chinensis water or alcoholic acid extract again.
Described extract can be processed as said dosage form on any pharmaceutics.Contain acceptable carrier or additive on the materia medica in the described extract.
In addition, the invention still further relates to a kind of preparation is the method that main effect is used for the drug extract of " modern civilization diseases " such as improvement and treatment network syndromes with resisting fatigue, radioprotective, anti-melancholy, and according to first embodiment, this method may further comprise the steps:
1, with 9～45 weight portion Radix Ginsengs with alcoholic solution or flooding, through chromatography purification, drying, the extract of winning;
2, with 4～30 weight portion Radix Glycyrrhizaes, 9～60 weight portion Radix Et Caulis Acanthopanacis Senticosis with alcoholic solution or flooding, filtration, concentrate, dry, second extract;
3, second extract that first extract and the step 2 that step 1 is obtained obtains mixes pulverizing, sieves, and gets extract of the present invention.
According to second embodiment of the present invention, in step 2, add 9～45 weight portion Rhizoma Atractylodis Macrocephalaes, 9～45 weight portion Poria, water or ethanol extraction, concentrated, the dry extract that gets are pulverized the extract of gained then with first extract that step 1 obtains, get the another extract of the present invention.
According to the 3rd embodiment of the present invention, with 3～27 weight portion Fructus Schisandrae Chinensis waters or alcoholic acid extraction, concentrate, dry a extract, then its extract with the second embodiment gained is pulverized, another extract of the present invention.
The invention still further relates to a kind of preparation is the method that main effect is used for the drug extract of " modern civilization diseases " such as improvement and treatment network syndromes with resisting fatigue, radioprotective, anti-melancholy, this method may further comprise the steps: it is characterized in that described 9～45 weight portion Radix Ginsengs, 4～30 weight portion Radix Glycyrrhizaes, 9～60 weight portion Radix Et Caulis Acanthopanacis Senticosis, 9～45 weight portion Rhizoma Atractylodis Macrocephalaes, 9～45 weight portion Poria, 3～27 weight portion Fructus Schisandrae Chinensis waters or alcoholic solution are mixed decoction, concentrate, get thick paste, drying gets water extract and ethanol extract again, pulverizes.
In other words, as well known to those skilled in the art, can be respectively adopt known method extract various raw materials of the present invention, or mix with various combination carry, dry, concentrate, pulverize and make extract of the present invention; Or make separately dry extract respectively, carry out dried, crushing screening, mixed then the mixture that contains various raw extracts of the present invention.
The invention further relates to described pharmaceutical composition or extract and can be used for making health food or food nutrition agent.
Pharmaceutical composition of the present invention or extract as a kind of being that main effect is used for improving and the nutrient (medicine) of treatment network syndrome etc. " modern civilization diseases " with resisting fatigue, radioprotective, anti-melancholy, have the function of defying age and human body immunity improving power concurrently, take the various symptoms that both can improve " modern civilization disease " for a long time, but body building again.Pharmaceutical composition of the present invention or extract have following characteristic and melancholy point:
1, the selected raw material of pharmaceutical composition of the present invention or extract, polyphyly medicated diet homology food plant, each component meets People's Republic of China's " health food management method " and Medicine Act regulation, nontoxic (pair) effect, people can take for a long time.
2, pharmaceutical composition of the present invention or extract can improve comprehensively and treat the various symptoms of " modern civilization diseases " such as network syndromes, its effect is obvious, takes usually can improve after 15 days (course of treatment) to be in the subjective and objective Signs of above-mentioned sub-health state crowd.
3, pharmaceutical composition of the present invention or extract have anti-senescence function concurrently, take for a long time to strengthen body immunity.
4, pharmaceutical composition of the present invention or extract not only prove the various symptoms that can effectively improve and treat " modern civilization diseases " such as network syndromes through human body and animal experiment, and have found out its major function factor (ginsenoside, enoxolone, Radix Et Caulis Acanthopanacis Senticosi glucoside) and the mechanism of action.
5, pharmaceutical composition of the present invention or extract need not to decoct, and be easy to carry and use, meets People's Republic of China's health legislation regulation.
6, pharmaceutical composition of the present invention or extract have the potential value that is developed further into series of products (nutrient, health food, medicine).
The range of application of pharmaceutical composition of the present invention or extract:
1, this product can be used as nutrient, health food, the medicine that improves " modern civilization diseases " such as network syndromes.
2, this product can be used as " modern civilization diseases " such as improvement and treatment network syndromes.
Description of drawings:
Accompanying drawing 1 is the technological process 1 of the inventive method.
Accompanying drawing 2 is the technological process 2 of the inventive method.
Accompanying drawing 3 is the technological process 3 of the inventive method.
Claims (23)
1, a kind of pharmaceutical composition is characterized in that it is the medicament of being made by the following weight proportion raw material: Radix Ginseng 9～45 weight portions, Radix Glycyrrhizae 4～30 weight portions, Radix Et Caulis Acanthopanacis Senticosi 9～60 weight portions.
2, pharmaceutical composition according to claim 1 is characterized in that it is the medicament of being made by the following weight proportion raw material: Radix Ginseng 18～36 weight portions, Radix Glycyrrhizae 8～27 weight portions, Radix Et Caulis Acanthopanacis Senticosi 18～50 weight portions.
3, pharmaceutical composition according to claim 1 is characterized in that it is the medicament of being made by the following weight proportion raw material: Radix Ginseng 27 weight portions, Radix Glycyrrhizae 18 weight portions, Radix Et Caulis Acanthopanacis Senticosi 45 weight portions.
4,, it is characterized in that to add again 9～45 weight portion Rhizoma Atractylodis Macrocephalaes, 9～45 weight portion Poria according to each described pharmaceutical composition in the claim 1～3.
5, pharmaceutical composition according to claim 3 is characterized in that adding the 27 weight portion Rhizoma Atractylodis Macrocephalaes, 27 weight portion Poria again.
6, pharmaceutical composition according to claim 4 is characterized in that adding 3～27 weight portion Fructus Schisandrae Chinensis again.
7, pharmaceutical composition according to claim 5 is characterized in that adding 9 weight portion Fructus Schisandrae Chinensis again.
8,, it is characterized in that containing in the described pharmaceutical composition acceptable carrier on the materia medica according to the described pharmaceutical composition of claim 1～6.
9, a kind of drug extract is characterized in that this extract obtains through following method:
1. with 9～45 weight portion Radix Ginsengs with alcoholic solution or flooding, through the chromatography purification, drying, the extract of winning;
2. with 4～30 weight portion Radix Glycyrrhizaes, 9～60 weight portion Radix Et Caulis Acanthopanacis Senticosis with alcoholic solution or flooding, filtration, concentrate, dry, second extract;
3. second extract that 2. first extract that 1. step is obtained and step obtain mixes to be pulverized, and sieves, and gets thing of the present invention.
10, drug extract according to claim 8 is characterized in that it is made by the following weight proportion raw material: Radix Ginseng 18～30 weight portions, Radix Glycyrrhizae 8～27 weight portions, Radix Et Caulis Acanthopanacis Senticosi 18～50 weight portions.
11, drug extract according to claim 8 is characterized in that it is made by the following weight proportion raw material: Radix Ginseng 27 weight portions, Radix Glycyrrhizae 18 weight portions, Radix Et Caulis Acanthopanacis Senticosi 45 weight portions.
12, drug extract according to claim 8 is characterized in that adding the water or the alcoholic acid extract of 9～45 weight portion Rhizoma Atractylodis Macrocephalaes, 9～45 weight portion Poria again.
13, drug extract according to claim 12 is characterized in that adding the water or the alcoholic acid extract of 3～27 weight portion Fructus Schisandrae Chinensis again.
14, according to Claim 8 any one described drug extract is characterized in that described extract can be processed into said dosage form on any pharmaceutics～13.
15, according to Claim 8 any one described drug extract is characterized in that containing in the described extract carrier of accepting on the materia medica～13.
16, according to Claim 8 any one described drug extract is preparing with the application in " modern civilization disease " medicine, nutrient, the health foods such as improvement and treatment network syndrome, chronic fatigue syndrome and office's syndrome～13.
17, a kind of method for preparing drug extract is characterized in that:
1. with 9～45 weight portion Radix Ginsengs with alcoholic solution or flooding, through the chromatography purification, drying, the extract of winning;
2. with 4～30 weight portion Radix Glycyrrhizaes, 9～60 weight portion Radix Et Caulis Acanthopanacis Senticosis with alcoholic solution or flooding, filtration, concentrate, dry, second extract;
3. second extract that 2. first extract that 1. step is obtained and step obtain mixes to be pulverized, and sieves, and gets thing of the present invention.
18, the method for drug extract according to claim 17, it is characterized by and in 2., add 9～45 weight portion Rhizoma Atractylodis Macrocephalaes, 9～45 weight portion Poria waters or ethanol extraction, concentrated, the dry extract that gets again, then it is pulverized with the 1. extract of gained, extract of the present invention.
19, extract drugs method according to claim 18, it is characterized in that 3～27 weight portion Fructus Schisandrae Chinensis waters or ethanol extraction, concentrate, dry a extract, then its extract with claim 17 gained is pulverized, got extract of the present invention.
20, a kind of method for preparing extract drugs is characterized in that described 9～45 weight portion Radix Ginsengs, 4～30 weight portion Radix Glycyrrhizaes, 9～60 weight portion slender acanthopanaxs, 9～45 weight portion Rhizoma Atractylodis Macrocephalaes, 9～45 weight portion Poria, 3～27 weight portion Fructus Schisandrae Chinensis are decocted, concentrate, get thick paste, drying, pulverizing with various combination blending water or alcoholic solution; Or, get extracting solution separately with they water or alcoholic solution extractions respectively, and concentrate, get thick paste, drying gets water extract or ethanol extract respectively again, mixes pulverizing.
21, according to any one described pharmaceutical composition in the claim 1～6, it is characterized in that to be processed into powder, capsule and tablet.
22, a kind of by any one described pharmaceutical composition in the claim 1～6, the purposes in preparation nutrient or health food.
23, a kind of by the purposes of the described drug extract of claim 9～13 in preparation nutrient or health food.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2003101022870A CN1611232A (en) | 2003-10-30 | 2003-10-30 | Medicinal composition with main effect of antifatigue, radioresistance and melancholia-resistance and its preparing method |
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| Application Number | Priority Date | Filing Date | Title |
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| CNA2003101022870A CN1611232A (en) | 2003-10-30 | 2003-10-30 | Medicinal composition with main effect of antifatigue, radioresistance and melancholia-resistance and its preparing method |
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| CN1611232A true CN1611232A (en) | 2005-05-04 |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006099783A1 (en) * | 2005-03-25 | 2006-09-28 | Beijing Wonner Biotech Ltd. Co. | A pharmaceutical composition for treating depression and method for preparation thereof |
| CN101810323A (en) * | 2009-02-23 | 2010-08-25 | 天津丹溪国药研究所 | Health-care food capable of strengthening immunity and radiation resisting function |
| WO2010133016A1 (en) * | 2009-05-21 | 2010-11-25 | Zhang Zuoguang | Pharmaceutical composition for treating depression, preparation method and use therefor |
| JP2011504886A (en) * | 2007-11-30 | 2011-02-17 | チイヨウフン | Pharmaceutical composition for the treatment of anxiety |
| CN102688270A (en) * | 2012-06-18 | 2012-09-26 | 北华大学 | Anti-fatigue compound preparation of ginseng and acanthopanax |
| CN105232620A (en) * | 2015-11-11 | 2016-01-13 | 郑州后羿制药有限公司 | Traditional Chinese medicine immunopotentiator for poultry and preparing method of traditional Chinese medicine immunopotentiator |
| CN105950337A (en) * | 2016-05-19 | 2016-09-21 | 广州暨南生物医药研究开发基地有限公司 | Hibiscus manihot health care yellow wine as well as preparation method and application thereof |
| CN106883975A (en) * | 2017-03-29 | 2017-06-23 | 贵州穗蓝酒业科技有限公司 | A kind of functional form dinner party with singsong girls in attendance and preparation method thereof |
-
2003
- 2003-10-30 CN CNA2003101022870A patent/CN1611232A/en active Pending
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006099783A1 (en) * | 2005-03-25 | 2006-09-28 | Beijing Wonner Biotech Ltd. Co. | A pharmaceutical composition for treating depression and method for preparation thereof |
| JP2008533180A (en) * | 2005-03-25 | 2008-08-21 | ペイチィンオウナアルシンウコンチンチィスヨウシェンコンス | Drug composition for the treatment of depression and method for producing the same |
| US9572827B2 (en) | 2005-03-25 | 2017-02-21 | Beijing Wonner Biotech. Ltd. Co. | Pharmaceutical composition for treating depression and method for preparation thereof |
| JP2011504886A (en) * | 2007-11-30 | 2011-02-17 | チイヨウフン | Pharmaceutical composition for the treatment of anxiety |
| CN101810323A (en) * | 2009-02-23 | 2010-08-25 | 天津丹溪国药研究所 | Health-care food capable of strengthening immunity and radiation resisting function |
| WO2010133016A1 (en) * | 2009-05-21 | 2010-11-25 | Zhang Zuoguang | Pharmaceutical composition for treating depression, preparation method and use therefor |
| CN102688270A (en) * | 2012-06-18 | 2012-09-26 | 北华大学 | Anti-fatigue compound preparation of ginseng and acanthopanax |
| CN105232620A (en) * | 2015-11-11 | 2016-01-13 | 郑州后羿制药有限公司 | Traditional Chinese medicine immunopotentiator for poultry and preparing method of traditional Chinese medicine immunopotentiator |
| CN105950337A (en) * | 2016-05-19 | 2016-09-21 | 广州暨南生物医药研究开发基地有限公司 | Hibiscus manihot health care yellow wine as well as preparation method and application thereof |
| CN105950337B (en) * | 2016-05-19 | 2019-05-31 | 广州暨南生物医药研究开发基地有限公司 | A kind of Golden flower Health care yellow wine and its preparation method and application |
| CN106883975A (en) * | 2017-03-29 | 2017-06-23 | 贵州穗蓝酒业科技有限公司 | A kind of functional form dinner party with singsong girls in attendance and preparation method thereof |
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