CN1658892A - 参与蛋白质－蛋白质相互作用的蛋白质亚群的分离方法 - Google Patents

参与蛋白质－蛋白质相互作用的蛋白质亚群的分离方法 Download PDF

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Publication number
CN1658892A
CN1658892A CN02829465.3A CN02829465A CN1658892A CN 1658892 A CN1658892 A CN 1658892A CN 02829465 A CN02829465 A CN 02829465A CN 1658892 A CN1658892 A CN 1658892A
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CN
China
Prior art keywords
protein
proteins
holder
interactions
mixture
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Pending
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CN02829465.3A
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English (en)
Chinese (zh)
Inventor
D·L·阿尔康
T·J·尼尔森
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Blanchette Rockefeller Neurosciences Institute
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Blanchette Rockefeller Neurosciences Institute
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Application filed by Blanchette Rockefeller Neurosciences Institute filed Critical Blanchette Rockefeller Neurosciences Institute
Publication of CN1658892A publication Critical patent/CN1658892A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
CN02829465.3A 2002-08-14 2002-08-14 参与蛋白质－蛋白质相互作用的蛋白质亚群的分离方法 Pending CN1658892A (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2002/025845 WO2004019967A1 (fr) 2002-08-14 2002-08-14 Procede d'isolement de sous-populations de proteines impliquees dans les interactions proteine-proteine

Publications (1)

Publication Number Publication Date
CN1658892A true CN1658892A (zh) 2005-08-24

Family

ID=31975561

Family Applications (1)

Application Number Title Priority Date Filing Date
CN02829465.3A Pending CN1658892A (zh) 2002-08-14 2002-08-14 参与蛋白质－蛋白质相互作用的蛋白质亚群的分离方法

Country Status (6)

Country Link
EP (1) EP1556065A4 (fr)
JP (1) JP2005535727A (fr)
CN (1) CN1658892A (fr)
AU (1) AU2002326644A1 (fr)
CA (1) CA2492324A1 (fr)
WO (1) WO2004019967A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI3465207T1 (sl) 2016-05-30 2022-01-31 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E. V. Identifikacija ligandov s KO-frakcionacijo
CN109932444B (zh) * 2019-03-19 2022-03-11 北京泰德制药股份有限公司 一种糖蛋白多种电荷异构体翻译后修饰的评价方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5817789A (en) * 1995-06-06 1998-10-06 Transkaryotic Therapies, Inc. Chimeric proteins for use in transport of a selected substance into cells

Also Published As

Publication number Publication date
JP2005535727A (ja) 2005-11-24
WO2004019967A1 (fr) 2004-03-11
EP1556065A4 (fr) 2005-10-19
CA2492324A1 (fr) 2004-03-11
AU2002326644A1 (en) 2004-03-19
EP1556065A1 (fr) 2005-07-27

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C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication