CN1662261A - 通过多聚－l－谷氨酸(“plg”）系统增加核酸构建体的体内递送 - Google Patents

通过多聚－l－谷氨酸(“plg”）系统增加核酸构建体的体内递送 Download PDF

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Publication number
CN1662261A
CN1662261A CN 03814625 CN03814625A CN1662261A CN 1662261 A CN1662261 A CN 1662261A CN 03814625 CN03814625 CN 03814625 CN 03814625 A CN03814625 A CN 03814625A CN 1662261 A CN1662261 A CN 1662261A
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CN
China
Prior art keywords
seqid
nucleic acid
acid expression
expression construct
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN 03814625
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English (en)
Chinese (zh)
Inventor
R·德拉吉亚－阿克里
R·H·卡彭特
D·R·克恩
L·A·希尔
H·阿特拉
H·赫布尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Advisys Inc
Original Assignee
Advisys Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/395,709 external-priority patent/US20040014645A1/en
Application filed by Advisys Inc filed Critical Advisys Inc
Publication of CN1662261A publication Critical patent/CN1662261A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CN 03814625 2002-05-28 2003-05-23 通过多聚－l－谷氨酸(“plg”）系统增加核酸构建体的体内递送 Pending CN1662261A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US15667002A 2002-05-28 2002-05-28
US10/156,670 2002-05-28
US10/395,709 US20040014645A1 (en) 2002-05-28 2003-03-24 Increased delivery of a nucleic acid construct in vivo by the poly-L-glutamate ("PLG") system
US10/395,709 2003-03-24

Publications (1)

Publication Number Publication Date
CN1662261A true CN1662261A (zh) 2005-08-31

Family

ID=29586320

Family Applications (1)

Application Number Title Priority Date Filing Date
CN 03814625 Pending CN1662261A (zh) 2002-05-28 2003-05-23 通过多聚－l－谷氨酸(“plg”）系统增加核酸构建体的体内递送

Country Status (7)

Country Link
EP (1) EP1513559A4 (de)
CN (1) CN1662261A (de)
AU (1) AU2003273142A1 (de)
BR (1) BR0311539A (de)
CA (1) CA2485976A1 (de)
MX (1) MXPA04011766A (de)
WO (1) WO2003099341A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005089810A1 (ja) * 2004-03-22 2005-09-29 Kansai Technology Licensing Organization Co., Ltd. エレクトロポレーション法を用いたヒト骨形成因子遺伝子導入による骨誘導方法
WO2006014737A2 (en) * 2004-07-23 2006-02-09 Advisys, Inc. Growth hormone releasing hormone enhances the immune response induced by vaccination

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1204321B1 (de) * 1999-07-26 2005-11-09 Baylor College Of Medicine Superaktive, wachstumshormone freisetzende hormonanaloge vom schwein
CA2401327C (en) * 2000-03-03 2014-05-06 Valentis, Inc. Nucleic acid formulations comprising poly-amino acids for gene delivery and methods of use
AR037778A1 (es) * 2001-12-11 2004-12-01 Advisys Inc Suplementacion mediada por plasmido para el tratamiento de sujetos cronicamente enfermos

Also Published As

Publication number Publication date
AU2003273142A1 (en) 2003-12-12
CA2485976A1 (en) 2003-12-04
EP1513559A4 (de) 2006-01-18
MXPA04011766A (es) 2005-03-31
EP1513559A1 (de) 2005-03-16
BR0311539A (pt) 2005-10-25
WO2003099341A1 (en) 2003-12-04

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication