CN1671734A - 用于治疗囊性纤维化的cftr修饰基因和表达的多肽以及检测和/或鉴定它们的方法和产品 - Google Patents

用于治疗囊性纤维化的cftr修饰基因和表达的多肽以及检测和/或鉴定它们的方法和产品 Download PDF

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Publication number
CN1671734A
CN1671734A CNA038183471A CN03818347A CN1671734A CN 1671734 A CN1671734 A CN 1671734A CN A038183471 A CNA038183471 A CN A038183471A CN 03818347 A CN03818347 A CN 03818347A CN 1671734 A CN1671734 A CN 1671734A
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China
Prior art keywords
cftr
modifying factor
benzoglyoxaline
protein
instrumentality
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Pending
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CNA038183471A
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English (en)
Chinese (zh)
Inventor
杰弗里·A·惠蔡特
布鲁斯·J·阿罗诺
琼·C·京拉克
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Cincinnati Childrens Hospital Medical Center
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Cincinnati Childrens Hospital Medical Center
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Publication of CN1671734A publication Critical patent/CN1671734A/zh
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4712Cystic fibrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/12Mucolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Rheumatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Pyrane Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CNA038183471A 2002-05-31 2003-05-30 用于治疗囊性纤维化的cftr修饰基因和表达的多肽以及检测和/或鉴定它们的方法和产品 Pending CN1671734A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US38485502P 2002-05-31 2002-05-31
US38485602P 2002-05-31 2002-05-31
US60/384,855 2002-05-31
US60/384,856 2002-05-31

Publications (1)

Publication Number Publication Date
CN1671734A true CN1671734A (zh) 2005-09-21

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Family Applications (1)

Application Number Title Priority Date Filing Date
CNA038183471A Pending CN1671734A (zh) 2002-05-31 2003-05-30 用于治疗囊性纤维化的cftr修饰基因和表达的多肽以及检测和/或鉴定它们的方法和产品

Country Status (6)

Country Link
EP (1) EP1513870A4 (fr)
JP (1) JP2005528449A (fr)
CN (1) CN1671734A (fr)
AU (1) AU2003238791A1 (fr)
CA (1) CA2488012A1 (fr)
WO (1) WO2003102140A2 (fr)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101392026B (zh) * 2008-10-09 2011-11-09 黄岚 用于预防和治疗纤维化类疾病以及肝癌的多肽
CN103025889A (zh) * 2010-03-22 2013-04-03 艾索特里克斯遗传实验室有限责任公司 与囊性纤维化关联的突变
CN105142676A (zh) * 2013-03-14 2015-12-09 夏尔人类遗传性治疗公司 Cftr mrna组合物以及相关方法和用途
CN109280704A (zh) * 2018-10-12 2019-01-29 郑州大学第附属医院 Rasd1作为标志物在制备b-all诊断和预后评估试剂盒中的应用
CN113164425A (zh) * 2018-10-30 2021-07-23 佛罗里达大学研究基金会公司 用于治疗囊性纤维化的氨基酸组合物和方法
CN113604583A (zh) * 2021-08-10 2021-11-05 河南省畜牧总站 一种山羊kcnj15基因cnv标记辅助检测生长性状的方法及其专用试剂盒

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013021399A1 (fr) * 2011-08-05 2013-02-14 Council Of Scientific & Industrial Research Diterpènes pimaranes provenant de anisochilus verticillatus
WO2014058974A1 (fr) * 2012-10-10 2014-04-17 Emory University Méthodes de gestion d'inflammation au moyen d'inhibiteurs de la voie de la glycolyse
US20240076682A1 (en) * 2022-08-29 2024-03-07 Universita' Degli Studi Di Bari Aldo Moro Promoter of the transcription of nucleic acid sequence an its use

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101392026B (zh) * 2008-10-09 2011-11-09 黄岚 用于预防和治疗纤维化类疾病以及肝癌的多肽
CN103025889A (zh) * 2010-03-22 2013-04-03 艾索特里克斯遗传实验室有限责任公司 与囊性纤维化关联的突变
CN103025889B (zh) * 2010-03-22 2015-11-25 艾索特里克斯遗传实验室有限责任公司 与囊性纤维化关联的突变
CN105142676A (zh) * 2013-03-14 2015-12-09 夏尔人类遗传性治疗公司 Cftr mrna组合物以及相关方法和用途
CN105142676B (zh) * 2013-03-14 2022-06-28 夏尔人类遗传性治疗公司 Cftr mrna组合物以及相关方法和用途
CN109280704A (zh) * 2018-10-12 2019-01-29 郑州大学第附属医院 Rasd1作为标志物在制备b-all诊断和预后评估试剂盒中的应用
CN113164425A (zh) * 2018-10-30 2021-07-23 佛罗里达大学研究基金会公司 用于治疗囊性纤维化的氨基酸组合物和方法
CN113604583A (zh) * 2021-08-10 2021-11-05 河南省畜牧总站 一种山羊kcnj15基因cnv标记辅助检测生长性状的方法及其专用试剂盒
CN113604583B (zh) * 2021-08-10 2024-04-02 河南省畜牧总站 一种山羊kcnj15基因cnv标记辅助检测生长性状的方法及其专用试剂盒

Also Published As

Publication number Publication date
JP2005528449A (ja) 2005-09-22
EP1513870A4 (fr) 2006-06-07
EP1513870A2 (fr) 2005-03-16
AU2003238791A1 (en) 2003-12-19
WO2003102140A2 (fr) 2003-12-11
CA2488012A1 (fr) 2003-12-11
WO2003102140A3 (fr) 2004-06-10

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