CN1894198B - 生产α-氟代丙二酸二烷基酯的方法 - Google Patents
生产α-氟代丙二酸二烷基酯的方法 Download PDFInfo
- Publication number
- CN1894198B CN1894198B CN200480023543XA CN200480023543A CN1894198B CN 1894198 B CN1894198 B CN 1894198B CN 200480023543X A CN200480023543X A CN 200480023543XA CN 200480023543 A CN200480023543 A CN 200480023543A CN 1894198 B CN1894198 B CN 1894198B
- Authority
- CN
- China
- Prior art keywords
- triethylamine
- hydrogen fluoride
- fluoromalonate
- hydrogen
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 0 *C(C(*)=O)(C(*)=O)Cl Chemical compound *C(C(*)=O)(C(*)=O)Cl 0.000 description 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/307—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10337885.5 | 2003-08-18 | ||
| DE10337885A DE10337885A1 (de) | 2003-08-18 | 2003-08-18 | Verfahren zur Herstellung von α-Fluormalonsäuredialkylestern |
| PCT/EP2004/009117 WO2005019154A1 (de) | 2003-08-18 | 2004-08-13 | VERFAHREN ZUR HERSTELLUNG VON α-FLUOR-MALONSÄUREDIALKYLESTERN |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1894198A CN1894198A (zh) | 2007-01-10 |
| CN1894198B true CN1894198B (zh) | 2012-07-18 |
Family
ID=34201625
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200480023543XA Expired - Lifetime CN1894198B (zh) | 2003-08-18 | 2004-08-13 | 生产α-氟代丙二酸二烷基酯的方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7807851B2 (2) |
| EP (2) | EP2261198A1 (2) |
| JP (3) | JP2007502793A (2) |
| KR (1) | KR101167233B1 (2) |
| CN (1) | CN1894198B (2) |
| BR (1) | BRPI0413686B1 (2) |
| DE (1) | DE10337885A1 (2) |
| DK (1) | DK1658259T3 (2) |
| ES (1) | ES2392051T3 (2) |
| IL (1) | IL173773A (2) |
| WO (1) | WO2005019154A1 (2) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100130768A1 (en) * | 2005-10-05 | 2010-05-27 | Daiichi Sankyo Company, Limited | Method for hydrodehalogenation of organic halogen compound |
| JP5642394B2 (ja) * | 2010-01-07 | 2014-12-17 | 日本曹達株式会社 | フッ化ジスルフィド化合物の製造方法 |
| US9193698B2 (en) | 2013-07-08 | 2015-11-24 | Advinus Therapeutics, Ltd. | Process for preparing fluoxastrobin |
| CN104418739A (zh) * | 2013-08-19 | 2015-03-18 | 上海元符医药科技有限公司 | 一种2-氟丙二酸二甲酯(i)的合成方法 |
| CN119095890A (zh) | 2022-11-04 | 2024-12-06 | 株式会社Lg化学 | 全息图记录介质和包括其的光学元件 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5391811A (en) * | 1992-11-10 | 1995-02-21 | Bayer Aktiengesellschaft | Process for the preparation of α-fluoro-β-dicarbonyl compounds |
| WO2002016304A1 (de) * | 2000-08-24 | 2002-02-28 | Bayer Cropscience Ag | VERFAHREN ZUR HERSTELLUNG VON α-FLUOR-MALONSÄUREDIALKYLESTERN |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2823969A1 (de) | 1978-06-01 | 1979-12-13 | Hoechst Ag | Verfahren zur herstellung organischer fluorverbindungen |
| JPS61180727A (ja) * | 1985-02-07 | 1986-08-13 | Tokuyama Soda Co Ltd | クロロジフルオロメチル基を有する芳香族化合物の製造方法 |
| DE4237892C2 (de) | 1992-11-10 | 1999-02-04 | Peter Wohland | Spender für verdunstbare Duftstoffe und Heilmittel |
| DE19602095A1 (de) | 1996-01-22 | 1997-07-24 | Bayer Ag | Halogenpyrimidine |
| JP3882856B2 (ja) * | 1996-05-16 | 2007-02-21 | 旭硝子株式会社 | α−フルオロ−β−ケトエステルの製造方法 |
| DE19646407A1 (de) | 1996-11-11 | 1998-05-14 | Bayer Ag | Halogenpyrimidine |
| DE19710609A1 (de) | 1997-03-14 | 1998-09-17 | Bayer Ag | Substituierte Aminosalicylsäureamide |
| JP3496460B2 (ja) * | 1997-06-13 | 2004-02-09 | ダイキン工業株式会社 | 電解液およびそれを用いるリチウム2次電池 |
| DE10104663A1 (de) * | 2001-02-02 | 2002-08-08 | Solvay Fluor & Derivate | Herstellung von Fluorverbindungen |
-
2003
- 2003-08-18 DE DE10337885A patent/DE10337885A1/de not_active Withdrawn
-
2004
- 2004-08-13 JP JP2006523586A patent/JP2007502793A/ja not_active Withdrawn
- 2004-08-13 WO PCT/EP2004/009117 patent/WO2005019154A1/de not_active Ceased
- 2004-08-13 CN CN200480023543XA patent/CN1894198B/zh not_active Expired - Lifetime
- 2004-08-13 US US10/568,355 patent/US7807851B2/en active Active
- 2004-08-13 KR KR1020067003271A patent/KR101167233B1/ko not_active Expired - Lifetime
- 2004-08-13 EP EP10175679A patent/EP2261198A1/de not_active Withdrawn
- 2004-08-13 EP EP04764111A patent/EP1658259B1/de not_active Expired - Lifetime
- 2004-08-13 BR BRPI0413686-1A patent/BRPI0413686B1/pt not_active IP Right Cessation
- 2004-08-13 DK DK04764111.3T patent/DK1658259T3/da active
- 2004-08-13 ES ES04764111T patent/ES2392051T3/es not_active Expired - Lifetime
-
2006
- 2006-02-16 IL IL173773A patent/IL173773A/en active IP Right Grant
-
2013
- 2013-06-28 JP JP2013136316A patent/JP2013241421A/ja active Pending
-
2014
- 2014-01-30 JP JP2014015157A patent/JP2014139174A/ja active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5391811A (en) * | 1992-11-10 | 1995-02-21 | Bayer Aktiengesellschaft | Process for the preparation of α-fluoro-β-dicarbonyl compounds |
| WO2002016304A1 (de) * | 2000-08-24 | 2002-02-28 | Bayer Cropscience Ag | VERFAHREN ZUR HERSTELLUNG VON α-FLUOR-MALONSÄUREDIALKYLESTERN |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2261198A1 (de) | 2010-12-15 |
| BRPI0413686A (pt) | 2006-10-24 |
| US20070191628A1 (en) | 2007-08-16 |
| DK1658259T3 (da) | 2012-11-12 |
| JP2007502793A (ja) | 2007-02-15 |
| IL173773A (en) | 2011-08-31 |
| US7807851B2 (en) | 2010-10-05 |
| CN1894198A (zh) | 2007-01-10 |
| WO2005019154A1 (de) | 2005-03-03 |
| EP1658259A1 (de) | 2006-05-24 |
| JP2013241421A (ja) | 2013-12-05 |
| IL173773A0 (en) | 2006-07-05 |
| ES2392051T3 (es) | 2012-12-04 |
| BRPI0413686B1 (pt) | 2015-02-10 |
| KR20060065699A (ko) | 2006-06-14 |
| DE10337885A1 (de) | 2005-03-24 |
| JP2014139174A (ja) | 2014-07-31 |
| EP1658259B1 (de) | 2012-07-25 |
| KR101167233B1 (ko) | 2012-07-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP5440555B2 (ja) | 高純度トリアルキルアルミニウム及びその製法 | |
| CN102030770B (zh) | 一种芳香硼酸酯化合物的制备方法 | |
| JP2014139174A (ja) | α−フルオロマロン酸ジアルキルエステルの製造方法 | |
| KR102079116B1 (ko) | 4-할로알킬-3-머캅토-치환된 2-하이드록시벤조산 유도체의 제조방법 | |
| JPH06219987A (ja) | α−フルオロ−β−ジカルボニル化合物の製造方法 | |
| US9650347B2 (en) | Process for producing pyridazinone compound and production intermediates thereof | |
| Enders et al. | α-Silyl controlled asymmetric michael additions of acyclic and cyclic ketones to nitroalkenes | |
| US7060862B2 (en) | Method for the preparation of α,α,α′,α′-tetrachloro-p-xylene with high purity | |
| JP7018327B2 (ja) | ベンズアルデヒド誘導体の製造方法 | |
| JP4032861B2 (ja) | β−オキソニトリル誘導体又はそのアルカリ金属塩の製法 | |
| JP4635251B2 (ja) | 有機ビスマス化合物およびその製法 | |
| US6992231B2 (en) | Method for the preparation of α,α, α′,α′-tetrachloro-p-xylene | |
| JPS6232188B2 (2) | ||
| JP6802815B2 (ja) | ジクロロキノン誘導体の製造方法 | |
| JP4188060B2 (ja) | 1−置換フェニル−ω−ブロモアルカンの製造法 | |
| JPH08113582A (ja) | 二官能アルキルホスフィンオキサイド及びその製造方法 | |
| EP0018144A1 (en) | A process for the preparation of substituted 2-aminopyrazines | |
| JP3864657B2 (ja) | 芳香族アクリロニトリルの製造法 | |
| JP6556476B2 (ja) | ジフルオロメチル亜鉛化合物 | |
| JP2004161703A (ja) | 2−フルオロ−4−(トリフルオロメチル)ベンゾニトリルの製造方法 | |
| JP3513726B2 (ja) | 2置換−1,3−インダンジオン誘導体の製造法 | |
| US20040176644A1 (en) | Process for producing 2-phenylacetophenone derivatives and precursons therefor | |
| JP2002201169A (ja) | 4−シアノ−3−オキソブタン酸エステルの製造法 | |
| US20020049350A1 (en) | Process for preparing thrombin receptor antagonist building blocks | |
| JP2006016365A (ja) | 3,3−ジアルコキシアクリル酸アルキルの製造方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20170713 Address after: German Monheim Patentee after: BAYER INTELLECTUAL PROPERTY GmbH Address before: German Monheim Patentee before: BAYER CROPSCIENCE AG |
|
| CP03 | Change of name, title or address |
Address after: 50 Alfred Nobel Street, Monheim, Rhine, Germany 40789 Patentee after: BAYER INTELLECTUAL PROPERTY GmbH Address before: Germany Patentee before: BAYER INTELLECTUAL PROPERTY GmbH |
|
| CP03 | Change of name, title or address | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20240112 Address after: 50 Alfred Nobel Street, Monheim, Rhine, Germany 40789 Patentee after: BAYER CROPSCIENCE AG Address before: 50 Alfred Nobel Street, Monheim, Rhine, Germany 40789 Patentee before: BAYER INTELLECTUAL PROPERTY GmbH |
|
| TR01 | Transfer of patent right | ||
| CX01 | Expiry of patent term |
Granted publication date: 20120718 |
|
| CX01 | Expiry of patent term |