CN210077657U - A dual feedback biostimulator - Google Patents

Abstract

The utility model relates to a two feedback biostimulators, include: a controller (1); a selection module (6); the stimulation module is respectively connected with the controller (1) and the selection module (6) and is used for providing voltage and current stimulation; the detection feedback module is respectively connected with the controller (1) and the detected biological object and is used for realizing voltage and current feedback regulation so that the voltage and the current applied to the detected biological object conform to expectations; the display module (7) is connected with the controller (1); the power supply module (8) is connected with the controller (1); and the communication module (9) is connected with the controller (1). Compared with the prior art, the stimulator integrates current and voltage double stimulation and can be used separately, the current linearity is good, and the interference is small; the voltage can output square wave voltage of-100V, and the range is large. The current and voltage double feedback based on the single chip microcomputer realizes accurate voltage and current control, is easy to operate, and protects a stimulation object from being damaged by large current and high voltage.

Description

A dual feedback biostimulator

technical field

The utility model relates to the field of physiology and pharmacology, in particular to a dual feedback biological stimulator.

Background technique

With the development of science and technology, in order to achieve a further understanding of natural life, more and more experimental instruments and equipment have been introduced into the study of physiology and pharmacology. In animal experiments, the stimulation system is an important part, that is, the stimulation is applied to the research object to cause changes in its physiological functions (ie, excitement). Different stimuli such as temperature, environmental changes, and dietary changes can make organisms excited and subsequently change their activity behaviors. Because electrical stimulation can easily and precisely control the degree of stimulation, and does little or no damage to biological tissue cells, it is the most common stimulation method in physiological and pharmacological experiments.

The quality of stimulation devices is the key to the success of physiological and pharmacological experiments. The stimulator should be set to a suitable square wave range, output a complete waveform, not difficult to guide, achieve the required stimulation intensity, and can stimulate repeatedly. Nowadays, the stimulators on the market are well developed, which can debug the width and voltage amplitude of the output ideal waveform, and have various output methods. The oscillating frequency is divided successively by the digital integrated circuit to generate various standard frequencies and time intervals, which can be used for timing counting and animal activity counting. Some stimulators are set to AC control, and when doing experiments such as provoked electrical convulsions, factors such as temperature can be considered and adjusted at the same time.

The current-limiting method of high-voltage stimulation can achieve the stimulation intensity generally required, but the stimulation intensity can only be controlled by controlling the amplitude of the output voltage. The single stimulation method cannot achieve high-precision effects, which has become a bottleneck in the development of pharmacological and physiological stimulators. .

Utility model content

The purpose of this utility model is to provide a dual-feedback biological stimulator in order to overcome the above-mentioned defects of the prior art.

The purpose of the present utility model can be achieved through the following technical solutions:

A dual feedback biostimulator comprising:

controller;

select module;

a stimulation module, which is respectively connected with the controller and the selection module;

a detection feedback module, which is respectively connected with the measured biological object and the described controller;

a display module, connected with the controller;

a power module, connected with the controller;

a communication module, connected with the controller;

The stimulation module is used to provide voltage stimulation and current stimulation. After the detection module feeds back the voltage and current of the biological object under test to the controller, the controller adjusts the voltage and current so that the voltage and current applied to the biological object under test are adjusted. The voltage and current meet the set conditions, and the selection module is used to switch the voltage and current stimulation modes.

The controller includes LPC1768 chip.

The stimulation module includes a D/A sub-module, a voltage stimulation sub-module and a current stimulation sub-module, and the D/A sub-module is respectively connected with the voltage stimulation sub-module, the current stimulation sub-module and the controller.

The voltage stimulation sub-module includes a voltage amplifier PA241DF chip, the current stimulation sub-module includes a current amplifier PA441DF chip, and the D/A sub-module includes a TLV5618A chip.

The selection module includes a relay.

The detection feedback module includes a voltage detection feedback sub-module and a current detection feedback sub-module which are independent of each other.

The voltage detection and feedback sub-module includes a window comparison circuit, and the window comparison circuit has a high and low level threshold, which is used for judging the voltage of the measured biological object.

The current detection and feedback sub-module includes an integrated Hall-effect linear current sensor and an A/D converter connected to each other. The Hall-effect linear current sensor collects the current of the biological object under test and transmits it to the controller through the A/D converter. .

The display module includes a drive chip and an LED display that are connected to each other.

The power module includes a 12V to 5V circuit and a 5V to 3.3V circuit.

Compared with the prior art, the utility model has the following advantages:

(1) Easy to operate, the magnitude of current and voltage can be output by the display module, and the operator is easy to monitor.

(2) The current and voltage dual stimulation is integrated, and the two stimulation methods are integrated into one, and a variety of stimulation methods can be implemented.

(3) Current stimulation and voltage stimulation can be used separately, the current stimulation current is large, can reach 20mA, the linearity is good and the interference is small, the voltage stimulation can output square wave voltage of -100V ~ 100V, and the range is large.

(4) It has a detection feedback module. After the voltage is judged by the high and low level thresholds set by the window comparison circuit, the judgment signal is transmitted to the controller, and then the gain or attenuation is automatically adjusted. The current detection feedback module transmits the current of the biological object under test. The signal is processed by the single-chip microcomputer, and then the current is displayed by the display module. The feedback module protects the stimulation object from the damage of high current and high voltage, and at the same time improves the accuracy of stimulation.

Description of drawings

1 is a schematic structural diagram of a dual-feedback biostimulator according to the present embodiment;

FIG. 2 is a circuit diagram of a voltage stimulation sub-module of the present embodiment;

3 is a circuit diagram of a current stimulation sub-module of the present embodiment;

FIG. 4 is a circuit diagram of the selection module of this embodiment;

FIG. 5 is a physical external structure diagram of the dual-feedback biostimulator of the present embodiment;

FIG. 6 is a physical internal structure diagram of the dual-feedback biostimulator according to the present embodiment.

Reference number:

1 is the controller; 2 is the voltage stimulation module; 3 is the current stimulation module; 4 is the voltage detection feedback sub-module; 5 is the current detection feedback sub-module; 6 is the selection module; 7 is the display module; 8 is the power module; 9 is the Communication module; 10 is a display screen; 11 is a voltage stimulation mode button; 12 is a current stimulation mode button; 13 is a switch button; 14 is a stimulation output port; 15 is a power port; 16 is a step-down module.

Detailed ways

The present utility model will be described in detail below with reference to the accompanying drawings and specific embodiments. This embodiment is implemented on the premise of the technical solution of the present invention, and provides a detailed implementation manner and a specific operation process, but the protection scope of the present invention is not limited to the following embodiments.

Example

As shown in Figures 1, 5, and 6, a dual-feedback biostimulator includes:

controller1;

select module 6;

The stimulation module is connected to the controller 1 and the selection module 6 respectively;

The detection feedback module is connected with the controller 1 and the measured biological object respectively;

The display module 7 is connected with the controller 1;

The power module 8 is connected to the controller 1;

The communication module 9 is connected with the controller 1;

The stimulation module is used to provide voltage and current stimulation, and the detection module feeds back the voltage and current of the detected biological object to the controller 1, and the controller 1 adjusts the voltage and current to make the voltage and current applied to the biological object to be tested meet expectations; the selection module 6 is used to switch the voltage and current stimulation mode.

The controller 1 adopts the LPC series microcontroller with high integration and low power consumption, specifically the LPC1768 chip.

The stimulation module includes a voltage stimulation sub-module 2 and a current stimulation sub-module 3. After the single-chip microcomputer sends the command, the D/A module outputs two voltages. After amplification, the APEX series high-voltage operational amplifier that can achieve the desired amplification factor is used. When the voltage is stimulated, the square wave voltage of -100V~100V is directly output, and the range is large and limited. When the current is stimulated, the input terminal is high impedance into the op amp circuit, and the output terminal is low impedance to form a current source. According to the requirements of the experimental stimulation intensity, the current size can be changed by the microcontroller, with good linearity and little interference. To achieve the integration of voltage and current stimulation. The circuits of the voltage stimulation sub-module 2 and the current stimulation sub-module 3 are shown in Figures 2 and 3.

The selection module 4 refers to the single-chip microcomputer control relay, which switches between the two modes of voltage stimulation 2 and current stimulation 3. The circuit structure is shown in Figure 4.

In the detection feedback module, the voltage detection feedback sub-module 4 is built with pure hardware. After dividing the voltage of the stimulus amplification circuit, the high and low level thresholds set by the window comparison circuit are used to judge the range and then send the signal to the controller 1. After automatically adjusting the appropriate range, select the appropriate gain or attenuation. The current detection feedback sub-module 5 uses a fully integrated Hall effect linear current sensor to convert the circuit under test into a proportional DC analog signal. After A/D conversion, the digital signal is sent to the controller 1 for processing, and then displayed by the display. Module 7 displays that due to the existence of the impedance of the biological object under test, the voltage and current applied to the biological object under test deviates from the expected voltage and current, and the detection feedback module enables this embodiment to form high-precision physiological and pharmacological stimulation.

Display module 7, mainly displays the detected voltage and current data and status of the output of the single-chip microcomputer, using LED serial static display, using the rising edge of the clock CLK terminal of the driver chip to shift the data output to the right by one bit, and adding a voltage divider resistor to protect the digital tube, Prevent high voltage from burning out the digital tube, and finally generate data results.

The communication module 9 adopts a level conversion circuit to convert the TTL level of the single-chip microcomputer into the serial port level of the PC, so as to achieve the communication between the single-chip computer and the PC.

The step-down module 16 reduces the 220V voltage to 12V, and the power module 8 has a 12V-to-5V circuit and a 5V-to-3.3V circuit to meet the power supply requirements of the system.

Compared with the prior art, the present embodiment adopts the integration of current stimulation and voltage stimulation, so there are more choices of stimulation intensity, the operation is simple, and the state is displayed intuitively by the display module, and the dual feedback of voltage detection feedback and current detection feedback is adopted to achieve higher precision .

In this embodiment, current stimulation and voltage stimulation can be used separately, the current stimulation current is large, can reach 20mA, the linearity is good and the interference is small, the voltage can output square wave voltage of -100V to 100V, and the range is large.

This embodiment has a detection feedback module to protect the stimulation object from being hurt by high current and high voltage.

Claims (10)

1. A dual feedback biostimulator, comprising:

a controller (1);

a selection module (6);

the stimulation module is respectively connected with the controller (1) and the selection module (6);

the detection feedback module is respectively connected with the detected biological object and the controller (1);

the display module (7) is connected with the controller (1);

the power supply module (8) is connected with the controller (1);

the communication module (9) is connected with the controller (1);

the stimulation module is used for providing voltage stimulation and current stimulation, after the detection feedback module feeds back the voltage and the current of the detected biological object to the controller (1), the controller (1) regulates the voltage and the current to enable the voltage and the current applied to the detected biological object to accord with set conditions, and the selection module (6) is used for switching the voltage and current stimulation mode.

2. A dual feedback biostimulator according to claim 1, characterized in that said controller (1) comprises a LPC1768 chip.

3. A dual feedback biostimulator according to claim 1, wherein said stimulation module comprises a D/a sub-module, a voltage stimulation sub-module (2) and a current stimulation sub-module (3), said D/a sub-modules being connected to the voltage stimulation sub-module (2), the current stimulation sub-module (3) and the controller (1), respectively.

4. A dual feedback biostimulator as claimed in claim 3, wherein said voltage stimulation sub-module (2) comprises a voltage amplifier PA241DF chip, said current stimulation sub-module (3) comprises a current amplifier PA441DF chip, and said D/a sub-module comprises a TLV5618A chip.

5. A dual feedback biostimulator according to claim 1, characterized in that said selection module (6) comprises a relay.

6. A dual feedback biostimulator as claimed in claim 1, wherein said sensing feedback module comprises a voltage sensing feedback sub-module (4) and a current sensing feedback sub-module (5) independent of each other.

7. A dual feedback biostimulator according to claim 6, wherein said voltage detection feedback sub-module (4) comprises a window comparison circuit having a high-low level threshold for making a high-low determination of the voltage of the biological subject being tested.

8. A dual feedback biostimulator as claimed in claim 6, wherein said current sensing feedback sub-module (5) comprises an integrated Hall Effect linear current sensor and an A/D converter connected to each other, said Hall Effect linear current sensor collecting the current of the biological subject to be tested and transmitting it to said controller (1) via said A/D converter.

9. A dual feedback biostimulator according to claim 1, characterized in that said display module (7) comprises a driver chip and an LED display connected to each other.

10. A dual feedback biostimulator as claimed in claim 1, wherein said power supply module (8) comprises a 12V to 5V circuit and a 5V to 3.3V circuit.

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