CN220137590U - Temperature control device for specific protein analyzer - Google Patents
Temperature control device for specific protein analyzer Download PDFInfo
- Publication number
- CN220137590U CN220137590U CN202321714059.8U CN202321714059U CN220137590U CN 220137590 U CN220137590 U CN 220137590U CN 202321714059 U CN202321714059 U CN 202321714059U CN 220137590 U CN220137590 U CN 220137590U
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- China
- Prior art keywords
- temperature control
- shell
- control device
- housing
- heating plate
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- 102000004169 proteins and genes Human genes 0.000 title claims abstract description 10
- 108090000623 proteins and genes Proteins 0.000 title claims abstract description 10
- 238000010438 heat treatment Methods 0.000 claims abstract description 62
- 238000003825 pressing Methods 0.000 claims abstract description 13
- 229920002379 silicone rubber Polymers 0.000 claims abstract description 7
- 238000009413 insulation Methods 0.000 claims description 7
- 229920000742 Cotton Polymers 0.000 claims description 6
- 239000007769 metal material Substances 0.000 claims description 5
- 229910000838 Al alloy Inorganic materials 0.000 claims description 3
- 229910052782 aluminium Inorganic materials 0.000 claims description 3
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 3
- 239000004945 silicone rubber Substances 0.000 claims description 3
- 238000000034 method Methods 0.000 abstract description 7
- 239000000565 sealant Substances 0.000 abstract description 4
- 238000005842 biochemical reaction Methods 0.000 abstract description 2
- 238000006243 chemical reaction Methods 0.000 description 15
- 239000012295 chemical reaction liquid Substances 0.000 description 9
- 238000012546 transfer Methods 0.000 description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 238000000338 in vitro Methods 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 2
- 210000001124 body fluid Anatomy 0.000 description 2
- 239000010839 body fluid Substances 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000002159 abnormal effect Effects 0.000 description 1
- 239000000022 bacteriostatic agent Substances 0.000 description 1
- 238000009529 body temperature measurement Methods 0.000 description 1
- 238000003759 clinical diagnosis Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 238000010030 laminating Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
Landscapes
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The utility model relates to the technical field of biochemical reaction discs, in particular to a temperature control device for a specific protein analyzer, which comprises: the shell is annular, and the surface between the two annular edges of the shell is recessed inwards from outside to inside along the axial direction to form two annular grooves along the axial direction; the shell mounting plate is fixedly connected with the bottom surface of the shell, and a closed cavity is formed inside the shell mounting plate and one of the annular grooves; the heating piece is arranged in the closed cavity; a temperature control switch for controlling the opening and closing of the heating plate and a temperature sensor for detecting the temperature of the shell. Compared with the method that the heating plate and the heating plate pressing plate are buried and packaged in the annular groove by using the pouring sealant, the utility model selects the method that the silicon rubber is arranged at the bottom of the heating plate and the shell is packaged by using the shell mounting plate, so that the temperature control device is simpler to assemble and more flexible to disassemble and assemble.
Description
Technical Field
The utility model relates to the technical field of biochemical reaction discs, in particular to a temperature control device for a specific protein analyzer.
Background
IVD (in vitro diagnosis, in Vitro Diagnostic) is a diagnostic method for obtaining clinical diagnosis information by in vitro detection of samples such as human body fluid, cells, tissues, etc., and further determining disease or body functions. In the working process of a specific protein analyzer, the reaction liquid needs to reach a set temperature value and can only fluctuate within an allowable range, and in the current implementation scheme, the reaction liquid mainly comprises the following components:
1. water bath mode. The reaction cup is partially immersed in water to heat the water, and the heat transfer mode is as follows: heating device- & gt water- & gt reaction cup wall- & gt reaction liquid. The temperature environment of the reaction of the solution in the reaction cup is controlled by controlling the temperature of water. The defects are as follows: the temperature rise time is long, a bacteriostatic agent and a foam inhibitor are required to be added, water must circulate and be replaced frequently, the structure is complex, and the cost is high.
2. An air bath mode. The reaction disk is sealed in a large cavity, the heating device heats the air in the cavity, and the heat transfer mode is as follows: heating device- & gt air- & gt reaction cup wall- & gt reaction liquid. The temperature of the reaction liquid in the reaction cup is controlled by controlling the temperature of the air. The defects are as follows: the heat transfer efficiency is low, the time for the reaction solution to reach the heat balance is long, the reaction solution is easily influenced by the ambient temperature, and the temperature fluctuation is large. The device for keeping the temperature constant by using a temperature control groove is also on the market, and CN201408191Y discloses a biochemical analyzer constant temperature system which comprises the temperature control groove, a reaction plate and a membrane heater, but the bottom groove of the temperature control groove is sealed by pouring sealant, and the packaging mode is inconvenient for production and assembly. Therefore, there is a need to develop a new temperature control device.
Disclosure of Invention
An object of an embodiment of the present utility model is to provide a temperature control device for a specific protein analyzer.
The embodiment of the utility model is realized in such a way that the temperature control device for the specific protein analyzer comprises a shell, wherein the shell is annular, and the surface between two annular edges of the shell is recessed inwards from outside to inside along the axial direction to form two annular grooves along the axial direction; the shell mounting plate is fixedly connected with the bottom surface of the shell, and a closed cavity is formed inside the shell mounting plate and one of the annular grooves; the heating piece is arranged in the closed cavity; a temperature control switch for controlling the heating plate to be opened and closed; and a temperature sensor for detecting the temperature of the housing.
Further, the temperature control device also comprises a heating plate pressing plate, wherein the heating plate presses the heating plate in the annular groove
Further, the shell mounting plate, the heating plate pressing plate and the heating plate are sequentially fixed on the shell through screws.
Further, the heating plate is provided with a heat insulating layer on a surface contacting with the heating plate pressing plate.
Further, the heat insulating layer is a silicone rubber layer.
Further, a shell heat-insulating cotton outer ring layer and a shell heat-insulating cotton inner ring layer are respectively arranged on the outer side surface and the inner side surface of the shell.
Further, the temperature control device further comprises a support frame, and the support frame is fixedly connected with the bottom of the shell mounting plate.
Further, the housing is made of a metal material.
Further, a light leakage hole is formed in the shell.
Further, the metal material is aluminum or aluminum alloy.
The utility model has the following beneficial effects: compared with the method that the heating plate and the heating plate pressing plate are buried and packaged in the annular groove by using the pouring sealant, the utility model selects the method that the silicon rubber is arranged at the bottom of the heating plate and the shell is packaged by using the shell mounting plate, so that the temperature control device is simpler to assemble and more flexible to disassemble and assemble.
Drawings
FIG. 1 is an exploded view of a temperature control device for a specific protein analyzer provided by the present utility model;
FIG. 2 is a schematic diagram of a temperature control device according to the present utility model;
FIG. 3 is a schematic diagram of a temperature control switch and a temperature sensor according to the present utility model.
Detailed Description
In order to make the technical problems, technical schemes and beneficial effects to be solved more clear, the utility model is further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the scope of the utility model.
The temperature control device provided by the utility model is suitable for a specific protein analyzer or other instruments needing to control the temperature of reaction liquid, and particularly as shown in figures 1-3, the temperature control device comprises a shell 1, a temperature control switch 2, a temperature sensor 3, a heating plate 4, a heating plate pressing plate 5 and a shell mounting plate 6. Wherein, casing 1 is provided with annular groove 11, and casing mounting panel 6 is connected with casing 1 bottom surface, covers annular groove 11, and casing mounting panel 6 and the inside closed cavity that forms of annular groove 11, heating plate 4 and heating plate clamp plate 5 set up in closed cavity, and heating plate 4 laminating annular groove 11 bottom surface sets up, and heating plate clamp plate 5 compresses tightly heating plate 4 on annular groove 11's bottom surface. The temperature control switch 2 is arranged on the shell 1, and the temperature sensor 3 is arranged in a preset hole of the shell 1.
Further, the casing 1 has an annular structure, and a surface between two annular edges of the casing is recessed from outside to inside along an axial direction to form an outer ring, an inner ring and a connecting rib sandwiched between the outer ring and the inner ring, wherein the inner walls of the outer ring and the inner ring and the upper surfaces of the connecting rib form a first annular groove, and the inner walls of the outer ring and the inner ring and the lower surfaces of the connecting rib form a second annular groove. The shell 1 is arranged in an annular structure, and a reaction disc (not shown in the figure) filled with the reaction liquid can be arranged in the middle of the shell 1, so that the reaction liquid is uniformly heated by the inner wall of the shell 1.
Further, the shell 1 is provided with a hole for placing the temperature sensor 3, and the temperature sensor 3 is placed in the hole, so that the temperature sensor 3 is directly contacted with the shell 1, and the accuracy and the sensitivity of temperature measurement of the temperature sensor are ensured. The two annular grooves on the shell 1 enable the heating plate 4 to be placed into one annular groove and attached to the inner wall of the annular groove, so that the heating plate 4 can conduct heat to the shell 1 directly, and heat transfer efficiency is improved. The material of the housing 1 is a metal material, for example, aluminum or an aluminum alloy, and the use of metal as the material of the housing 1 can improve heat transfer efficiency. The front and rear of the housing 1 are respectively provided with a first light leakage hole 12 and a second light leakage hole 13 which are respectively used for transmitting and scattering test reaction cup samples.
Further, the outer side surface and the inner side surface of the shell 1 are respectively provided with a shell heat insulation cotton outer ring layer 8 and a shell heat insulation cotton inner ring layer 9, which are used for heat insulation of the shell 1.
Further, the temperature control switch 2 is vertically buried in the outer ring side wall of the annular groove and is electrically connected with the heating plate 4, and the temperature control switch is arranged to disconnect the circuit when the heating temperature is detected to reach about 60 ℃, so that the heating plate 4 stops heating the shell 1, when the shell 1 dissipates heat in a heat conduction manner and the temperature drops below 30 ℃, the temperature control switch 2 connects the circuit, and the heating plate 4 is reheated to ensure that the temperature does not drop below room temperature. In addition, the temperature control switch 2 adopts a PID control algorithm, is used for realizing strict temperature control on the heating plate 4, so that the temperature of the heating plate 4 is maintained at about 37 ℃, an overheat protection function is added, and the switch is automatically turned off when the temperature reaches about 60 ℃, so that continuous heating is still realized when the heating plate 4 is abnormal, and accidents are prevented.
Further, the temperature sensor 3 is used for detecting the temperature of the shell 1, ensuring the environment of the shell 1 to be constant at about 37 degrees, and the temperature is more suitable for simulating the body fluid in the reaction cup in the human body environment.
Further, the heating plate 4 is annular, the shape of the heating plate is matched with that of the annular groove of the shell 1, a heat insulation layer (namely, one surface which is in contact with the heating plate pressing plate 5) is arranged on the surface which is not in contact with the inner wall of the annular groove, the heat insulation layer is preferably a silicon rubber layer with the thickness of 5mm, the heating plate 4 is packaged in the annular groove, and the heat transfer effect is better. In other embodiments, a heat insulating layer may be provided on the other side of the heating plate 4.
Further, the shape of the heating plate pressing plate 5 corresponds to that of the heating plate 4, and the heating plate pressing plate is pressed on the silicone rubber of the heating plate 4 to better compact the heating plate 4, prevent the heating plate 4 from falling off, enable the heating plate 4 to be fully contacted with the annular groove, and improve the heat transfer effect.
Further, the housing mounting plate 6 is used for compacting the heating plate pressing plate 5 and the heating plate 4 in the annular groove, preventing loosening of parts in the annular groove and sealing the bottom of the annular groove of the housing 1. The housing mounting plate 6, the heating sheet pressing plate 5, and the heating sheet 4 are fixed to the connection rib of the housing 1 in this order by screws.
Further, the temperature control device also comprises a supporting frame 7, and one end of the supporting frame 7 is fixedly connected with the bottom of the shell mounting plate 6 and used for supporting the whole temperature control device.
In use, the reaction liquid is filled into the bottle, the bottle is arranged around the reaction disc, and the reaction disc is placed in the middle of the shell 1, so that the bottle is close to the inner wall of the shell 1, and heat from the shell 1 can be better received.
Compared with the method that the heating plate and the heating plate pressing plate are buried and packaged in the annular groove by using the pouring sealant, the utility model selects the method that the silicon rubber is arranged at the bottom of the heating plate and the shell is packaged by using the shell mounting plate, so that the temperature control device is simpler to assemble and more flexible to disassemble and assemble.
The above description is only of the preferred embodiments of the present utility model and is not intended to limit the utility model, but any modifications, equivalents, improvements, etc. within the principles of the present utility model should be included in the scope of the present utility model.
Claims (10)
1. A temperature control device for a specific protein analyzer, comprising:
the shell is annular, and the surface between the two annular edges of the shell is recessed inwards from outside to inside along the axial direction to form two annular grooves along the axial direction;
the shell mounting plate is fixedly connected with the bottom surface of the shell, and a closed cavity is formed inside the shell mounting plate and one of the annular grooves;
the heating piece is arranged in the closed cavity;
a temperature control switch for controlling the heating plate to be opened and closed;
a temperature sensor for detecting the temperature of the housing.
2. The temperature control device of claim 1, further comprising a heat patch platen that presses the heat patch within the annular recess.
3. The temperature control device according to claim 2, wherein the housing mounting plate, the heating sheet pressing plate, and the heating sheet are sequentially fixed to the housing by screws.
4. The temperature control device according to claim 2, wherein a heat insulating layer is provided on one of the surfaces of the heating sheet.
5. The temperature control device of claim 4, wherein the thermally insulating layer is a silicone rubber layer.
6. The temperature control device of claim 1, wherein the housing outer and inner sides are provided with a housing insulation cotton outer ring layer and a housing insulation cotton inner ring layer, respectively.
7. The temperature control device of any one of claims 1-6, further comprising a support frame fixedly coupled to a bottom of the housing mounting plate.
8. The temperature control device of claim 7, wherein the housing is made of a metallic material.
9. The temperature control device of claim 7, wherein the housing is provided with a light leakage aperture.
10. The temperature control device of claim 8, wherein the metallic material is aluminum or an aluminum alloy.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321714059.8U CN220137590U (en) | 2023-06-30 | 2023-06-30 | Temperature control device for specific protein analyzer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321714059.8U CN220137590U (en) | 2023-06-30 | 2023-06-30 | Temperature control device for specific protein analyzer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN220137590U true CN220137590U (en) | 2023-12-05 |
Family
ID=88955914
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202321714059.8U Active CN220137590U (en) | 2023-06-30 | 2023-06-30 | Temperature control device for specific protein analyzer |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN220137590U (en) |
-
2023
- 2023-06-30 CN CN202321714059.8U patent/CN220137590U/en active Active
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