CR10067A - PRESERVATION AND / OR PERFUSION OF BODIES - Google Patents
PRESERVATION AND / OR PERFUSION OF BODIESInfo
- Publication number
- CR10067A CR10067A CR10067A CR10067A CR10067A CR 10067 A CR10067 A CR 10067A CR 10067 A CR10067 A CR 10067A CR 10067 A CR10067 A CR 10067A CR 10067 A CR10067 A CR 10067A
- Authority
- CR
- Costa Rica
- Prior art keywords
- organ
- perfusion
- preservation
- solution
- bodies
- Prior art date
Links
- 230000010412 perfusion Effects 0.000 title abstract 2
- 238000004321 preservation Methods 0.000 title abstract 2
- 210000000056 organ Anatomy 0.000 abstract 5
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 101710204837 Envelope small membrane protein Proteins 0.000 abstract 1
- 101710145006 Lysis protein Proteins 0.000 abstract 1
- 102000001253 Protein Kinase Human genes 0.000 abstract 1
- OUUQCZGPVNCOIJ-UHFFFAOYSA-M Superoxide Chemical compound [O-][O] OUUQCZGPVNCOIJ-UHFFFAOYSA-M 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 208000028867 ischemia Diseases 0.000 abstract 1
- 230000000302 ischemic effect Effects 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000010410 reperfusion Effects 0.000 abstract 1
- 238000002054 transplantation Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Environmental Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Dentistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Peptides Or Proteins (AREA)
Abstract
Solución de preservación, perfusión y/o reperfusión de un órgano, en especial el corazón, para transplantes. La solución contiene inhibidores de péptidos de proteína quinasa C E (PKC e). También se describen métodos para usar la solución de la invención, incluyendo métodos de preservación de un órgano para transplante, de protección de un órgano después de una isquemia, de mantenimiento de liberación de óxido nítrico y/o de liberación de superóxido en un órgano isquémico y de protección de un órgano contra los daños ocasionados cuando está aislado del sistema circulatorio.Preservation, perfusion and / or reperfusion solution of an organ, especially the heart, for transplants. The solution contains C E protein kinase peptide inhibitors (PKC e). Methods for using the solution of the invention are also described, including methods of preserving an organ for transplantation, of protecting an organ after an ischemia, of maintaining nitric oxide release and / or superoxide release in an ischemic organ. and protection of an organ against damage caused when it is isolated from the circulatory system.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74864505P | 2005-12-09 | 2005-12-09 | |
| US11/341,654 US7326353B2 (en) | 2001-11-27 | 2006-01-30 | Methods for reclaiming developing solvents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR10067A true CR10067A (en) | 2008-10-10 |
Family
ID=39324885
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR10067A CR10067A (en) | 2005-12-09 | 2008-06-12 | PRESERVATION AND / OR PERFUSION OF BODIES |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JP2009521410A (en) |
| AU (1) | AU2006349615B2 (en) |
| CA (1) | CA2632777C (en) |
| CR (1) | CR10067A (en) |
| DK (1) | DK2056851T3 (en) |
| WO (1) | WO2008051247A1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060160062A1 (en) * | 2005-01-14 | 2006-07-20 | Young Lindon H | Perfusion and/or preservation solution for organs |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001013916A1 (en) * | 1999-08-20 | 2001-03-01 | Sagami Chemical Research Center | Drugs inhibiting cell death |
| US20020168354A1 (en) * | 2000-11-10 | 2002-11-14 | Daria Mochly-Rosen | psiepsilonRack peptide composition and method for protection against tissue damage due to ischemia |
| WO2002057413A2 (en) * | 2001-01-18 | 2002-07-25 | The Board Of Trustees Of The Leland Stanford Junior University | Peptides for activation and inhibition of delta pkc |
| EP2228069A1 (en) * | 2003-09-16 | 2010-09-15 | Garvan Institute Of Medical Research | Antagonists of protein kinase c-epsilon (pkcepsilon) and their use for the treatment of aberrant glucose metabolism associated therewith. |
| CA2549052A1 (en) * | 2003-12-11 | 2005-06-30 | The Board Of Trustees Of The Leland Stanford Junior University | Isozyme-specific antagonists of protein kinase c |
| US7691861B2 (en) * | 2004-01-19 | 2010-04-06 | Novartis Ag | Indolymaleimide derivatives |
| US7265092B2 (en) * | 2004-09-30 | 2007-09-04 | Kai Pharmaceuticals, Inc. | Pharmaceutical formulation |
| US20060160062A1 (en) * | 2005-01-14 | 2006-07-20 | Young Lindon H | Perfusion and/or preservation solution for organs |
-
2006
- 2006-12-11 DK DK06847547.4T patent/DK2056851T3/en active
- 2006-12-11 WO PCT/US2006/047152 patent/WO2008051247A1/en not_active Ceased
- 2006-12-11 CA CA2632777A patent/CA2632777C/en active Active
- 2006-12-11 AU AU2006349615A patent/AU2006349615B2/en not_active Ceased
- 2006-12-11 JP JP2008544574A patent/JP2009521410A/en active Pending
-
2008
- 2008-06-12 CR CR10067A patent/CR10067A/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2006349615B2 (en) | 2012-09-20 |
| WO2008051247A1 (en) | 2008-05-02 |
| AU2006349615A1 (en) | 2008-05-02 |
| CA2632777A1 (en) | 2008-05-02 |
| JP2009521410A (en) | 2009-06-04 |
| CA2632777C (en) | 2019-08-20 |
| DK2056851T3 (en) | 2013-10-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal (granting procedure) |