CR10924A - Metodo para estabilidad mejorada de derivados de esteroides - Google Patents

Metodo para estabilidad mejorada de derivados de esteroides

Info

Publication number: CR10924A
Authority: CR; Costa Rica
Prior art keywords: improved stability; steroid derivatives; compositions; norprogesterone; steroids
Prior art date: 2007-01-17

Application number

CR10924A

Other languages

English (en)

Spanish (es)

Inventor

Podolski Joseph

Original Assignee

Repros Therapeutics Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-01-17

Filing date

2009-07-14

Publication date

2009-10-30

2009-07-14 Application filed by Repros Therapeutics Inc filed Critical Repros Therapeutics Inc

2009-10-30 Publication of CR10924A publication Critical patent/CR10924A/es

Links

150000003431 steroids Chemical class 0.000 title abstract 2
239000000203 mixture Substances 0.000 abstract 2
NVUUMOOKVFONOM-GPBSYSOESA-N 19-Norprogesterone Chemical compound C1CC2=CC(=O)CC[C@@H]2[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 NVUUMOOKVFONOM-GPBSYSOESA-N 0.000 abstract 1
230000001911 anti-progestational effect Effects 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000003389 potentiating effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
- C07C225/22—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/36—Antigestagens
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C221/00—Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
- C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Epidemiology (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Diabetes (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

CR10924A 2007-01-17 2009-07-14 Metodo para estabilidad mejorada de derivados de esteroides CR10924A (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US88536307P	2007-01-17	2007-01-17

Publications (1)

Publication Number	Publication Date
CR10924A true CR10924A (es)	2009-10-30

Family

ID=39387140

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CR10924A CR10924A (es)	2007-01-17	2009-07-14	Metodo para estabilidad mejorada de derivados de esteroides

Country Status (16)

Country	Link
EP (1)	EP2125858A2 (pt)
JP (1)	JP2010516686A (pt)
KR (1)	KR20090105944A (pt)
CN (1)	CN101616926A (pt)
AR (1)	AR064947A1 (pt)
AU (1)	AU2008206599A1 (pt)
BR (1)	BRPI0806572A2 (pt)
CA (1)	CA2674440A1 (pt)
CL (1)	CL2008000138A1 (pt)
CR (1)	CR10924A (pt)
EA (1)	EA200970692A1 (pt)
EC (1)	ECSP099537A (pt)
IL (1)	IL199684A0 (pt)
MX (1)	MX2009007313A (pt)
TW (1)	TW200835503A (pt)
WO (1)	WO2008088935A2 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TWI477276B (zh) *	2008-04-28	2015-03-21	Repros Therapeutics Inc	抗黃體素給藥方案
US8512745B2 (en)	2008-12-08	2013-08-20	Laboratoire Hra Pharma	Ulipristal acetate tablets
HUP0900171A2 (hu) *	2009-03-20	2010-12-28	Richter Gedeon Nyrt	17-acetoxi-11ß-[4-(dimetil-amino)-fenil]-21-metoxi-19-norpregna-4,9-dién-3,20-dion új kristályos módosulata és eljárás elõállítására
HUP0900487A2 (hu) *	2009-08-05	2011-03-28	Richter Gedeon Nyrt	17-acetoxi-11ß-[4-(dimetil-amino)-fenil]-21-metoxi-19-norpregna-4,9-dién-3,20-dion új kristályos polimorf módosulata és eljárás elõállítására

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA8231B (en) *	1981-01-09	1982-11-24	Roussel Uclaf	New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained
US6020328A (en) *	1998-03-06	2000-02-01	Research Triangle Institute	20-keto-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties
US8044223B2 (en) *	2003-04-04	2011-10-25	Bridge Organics Co.	Crystalline 19-norsteroids

2008
- 2008-01-03 BR BRPI0806572-1A patent/BRPI0806572A2/pt not_active IP Right Cessation
- 2008-01-03 CA CA002674440A patent/CA2674440A1/en not_active Abandoned
- 2008-01-03 WO PCT/US2008/050128 patent/WO2008088935A2/en not_active Ceased
- 2008-01-03 EP EP08713475A patent/EP2125858A2/en not_active Withdrawn
- 2008-01-03 KR KR1020097015532A patent/KR20090105944A/ko not_active Ceased
- 2008-01-03 CN CN200880002367A patent/CN101616926A/zh active Pending
- 2008-01-03 JP JP2009546454A patent/JP2010516686A/ja not_active Withdrawn
- 2008-01-03 EA EA200970692A patent/EA200970692A1/ru unknown
- 2008-01-03 MX MX2009007313A patent/MX2009007313A/es not_active Application Discontinuation
- 2008-01-03 AU AU2008206599A patent/AU2008206599A1/en not_active Abandoned
- 2008-01-15 TW TW097101566A patent/TW200835503A/zh unknown
- 2008-01-17 AR ARP080100217A patent/AR064947A1/es unknown
- 2008-01-17 CL CL200800138A patent/CL2008000138A1/es unknown
2009
- 2009-07-02 IL IL199684A patent/IL199684A0/en unknown
- 2009-07-14 CR CR10924A patent/CR10924A/es not_active Application Discontinuation
- 2009-07-23 EC EC2009009537A patent/ECSP099537A/es unknown

Also Published As

Publication number	Publication date
AU2008206599A1 (en)	2008-07-24
CN101616926A (zh)	2009-12-30
WO2008088935A2 (en)	2008-07-24
EA200970692A1 (ru)	2010-02-26
ECSP099537A (es)	2009-08-28
EP2125858A2 (en)	2009-12-02
MX2009007313A (es)	2009-07-15
KR20090105944A (ko)	2009-10-07
IL199684A0 (en)	2010-04-15
WO2008088935A3 (en)	2009-03-05
CA2674440A1 (en)	2008-07-24
BRPI0806572A2 (pt)	2014-05-06
CL2008000138A1 (es)	2008-05-16
AR064947A1 (es)	2009-05-06
TW200835503A (en)	2008-09-01
JP2010516686A (ja)	2010-05-20

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Legal Events

Date	Code	Title	Description
2014-02-05	FA	Abandonment or withdrawal (granting procedure)