CR20110640A - Derivados de amiloide p sérico/de suero y su preparación y uso - Google Patents
Derivados de amiloide p sérico/de suero y su preparación y usoInfo
- Publication number
- CR20110640A CR20110640A CR20110640A CR20110640A CR20110640A CR 20110640 A CR20110640 A CR 20110640A CR 20110640 A CR20110640 A CR 20110640A CR 20110640 A CR20110640 A CR 20110640A CR 20110640 A CR20110640 A CR 20110640A
- Authority
- CR
- Costa Rica
- Prior art keywords
- sérico
- serero
- amiloid
- derivatives
- preparation
- Prior art date
Links
- 101001092910 Homo sapiens Serum amyloid P-component Proteins 0.000 abstract 1
- 108010045517 Serum Amyloid P-Component Proteins 0.000 abstract 1
- 230000004071 biological effect Effects 0.000 abstract 1
- 150000004676 glycans Chemical group 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Un aspecto de la presente invención se refiere al sorprendente descubrimiento de que la modificación de una estructura de glicanos de un polipéptido SAP puede aumentar la actividad biológica en relación a una muestra de SAP de tipo salvaje aislado de suero humano. La divulgación proporciona tanto polipéptidos SAP humanos variantes y los métodos para hacer la misma.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21793109P | 2009-06-04 | 2009-06-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR20110640A true CR20110640A (es) | 2012-01-30 |
Family
ID=43298203
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR20110640A CR20110640A (es) | 2009-06-04 | 2011-11-29 | Derivados de amiloide p sérico/de suero y su preparación y uso |
Country Status (27)
| Country | Link |
|---|---|
| US (5) | US9296800B2 (es) |
| EP (2) | EP3042915B1 (es) |
| JP (3) | JP5801293B2 (es) |
| CN (1) | CN102574902B (es) |
| AU (1) | AU2010256426B2 (es) |
| BR (2) | BRPI1012924B8 (es) |
| CA (1) | CA2764461C (es) |
| CO (1) | CO6480917A2 (es) |
| CR (1) | CR20110640A (es) |
| CY (1) | CY1120817T1 (es) |
| DK (2) | DK2438083T3 (es) |
| EA (1) | EA030332B1 (es) |
| ES (2) | ES2692815T3 (es) |
| HR (2) | HRP20160221T1 (es) |
| HU (1) | HUE026737T2 (es) |
| IL (1) | IL216744A (es) |
| LT (1) | LT3042915T (es) |
| MX (1) | MX2011012738A (es) |
| MY (1) | MY158761A (es) |
| NZ (1) | NZ596849A (es) |
| PL (2) | PL3042915T3 (es) |
| PT (1) | PT3042915T (es) |
| SI (2) | SI3042915T1 (es) |
| TR (1) | TR201815592T4 (es) |
| UA (1) | UA110323C2 (es) |
| WO (1) | WO2010141918A1 (es) |
| ZA (1) | ZA201108857B (es) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5220025B2 (ja) * | 2006-12-04 | 2013-06-26 | プロメディオール, インコーポレイテッド | 線維症疾患を処置するための併用療法 |
| US20090092574A1 (en) | 2006-12-29 | 2009-04-09 | Scott Richard W | Ophthalmic And Otic Compositions Of Facially Amphiphilic Polymers And Oligomers And Uses Thereof |
| US8497243B2 (en) * | 2007-07-06 | 2013-07-30 | Promedior, Inc. | Methods and compositions useful in the treatment of mucositis |
| US9884899B2 (en) | 2007-07-06 | 2018-02-06 | Promedior, Inc. | Methods for treating fibrosis using CRP antagonists |
| PT2405929T (pt) * | 2009-03-11 | 2018-07-23 | Promedior Inc | Métodos de tratamento para distúrbios autoimunes |
| PT2405928T (pt) | 2009-03-11 | 2017-02-07 | Promedior Inc | Métodos de tratamento e de diagnóstico para patologias de hipersensibilidade |
| UA110323C2 (en) * | 2009-06-04 | 2015-12-25 | Promedior Inc | Derivative of serum amyloid p and their receipt and application |
| HUE041034T2 (hu) * | 2009-06-17 | 2019-05-28 | Promedior Inc | SAP-variánsok és alkalmazásuk |
| FR2969153B1 (fr) * | 2010-12-17 | 2014-10-17 | Lab Francais Du Fractionnement | Procede de purification de proteine amyloide p et utilisation de la proteine ainsi purifiee |
| DK2709619T3 (en) * | 2011-05-16 | 2018-01-15 | Cellceutix Corp | RELATIONSHIPS FOR USING THE TREATMENT OF MUCOSITIS |
| WO2013096847A1 (en) * | 2011-12-21 | 2013-06-27 | Promedior, Inc. | Serum amyloid p-antibody fusion proteins |
| RU2020111934A (ru) | 2013-10-08 | 2020-04-29 | Промедиор, Инк. | Способы лечения фиброзного рака |
| FR3012453B1 (fr) | 2013-10-31 | 2015-11-13 | Lab Francais Du Fractionnement | Proteine chimerique dans le traitement de l’amylose |
| CN105372214B (zh) * | 2014-08-18 | 2019-06-28 | 中国科学院上海有机化学研究所 | 一种鉴定新红细胞生成刺激蛋白的n-连接寡糖结构的方法 |
| KR20190045350A (ko) * | 2016-09-13 | 2019-05-02 | 바이엘 헬스케어 엘엘씨 | 인자 VIIa 당형태 |
| JP6852397B2 (ja) * | 2016-12-28 | 2021-03-31 | 株式会社島津製作所 | 分析用試料の調製方法および分析方法 |
| CN108114001B (zh) * | 2017-12-23 | 2023-05-30 | 中国科学院海洋研究所 | 一种诱导海产双壳贝类产卵的诱导剂及其应用方法 |
| US11771694B2 (en) | 2020-06-05 | 2023-10-03 | Innovation Pharmaceuticals Inc. | Arylamide compounds for treatment and prevention of viral infections |
| BR112023008317A2 (pt) * | 2020-11-02 | 2024-02-06 | Attralus Inc | Proteínas de fusão sap fc e métodos de uso |
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| GB8516081D0 (en) | 1985-06-25 | 1985-07-31 | Ciba Geigy Ag | Assay & purification of amyloid components |
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| US5047335A (en) | 1988-12-21 | 1991-09-10 | The Regents Of The University Of Calif. | Process for controlling intracellular glycosylation of proteins |
| US5092876A (en) | 1989-08-30 | 1992-03-03 | The United States Of America As Represented By The Department Of Health And Human Services | Cell attachment peptides derived from amyloid P component |
| WO1992021364A1 (en) | 1991-05-31 | 1992-12-10 | New England Deaconess Hospital Corporation | Cea-binding proteins and methods for their isolation and use |
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| US9884899B2 (en) | 2007-07-06 | 2018-02-06 | Promedior, Inc. | Methods for treating fibrosis using CRP antagonists |
| US8497243B2 (en) | 2007-07-06 | 2013-07-30 | Promedior, Inc. | Methods and compositions useful in the treatment of mucositis |
| PT2405929T (pt) | 2009-03-11 | 2018-07-23 | Promedior Inc | Métodos de tratamento para distúrbios autoimunes |
| PT2405928T (pt) * | 2009-03-11 | 2017-02-07 | Promedior Inc | Métodos de tratamento e de diagnóstico para patologias de hipersensibilidade |
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| HUE041034T2 (hu) | 2009-06-17 | 2019-05-28 | Promedior Inc | SAP-variánsok és alkalmazásuk |
-
2010
- 2010-04-06 UA UAA201115614A patent/UA110323C2/ru unknown
- 2010-06-04 BR BRPI1012924A patent/BRPI1012924B8/pt not_active IP Right Cessation
- 2010-06-04 PL PL15197076T patent/PL3042915T3/pl unknown
- 2010-06-04 HU HUE10784210A patent/HUE026737T2/en unknown
- 2010-06-04 BR BR122020010980-7A patent/BR122020010980B1/pt active IP Right Grant
- 2010-06-04 EA EA201171490A patent/EA030332B1/ru unknown
- 2010-06-04 PL PL10784210T patent/PL2438083T3/pl unknown
- 2010-06-04 EP EP15197076.1A patent/EP3042915B1/en active Active
- 2010-06-04 MY MYPI2011005861A patent/MY158761A/en unknown
- 2010-06-04 MX MX2011012738A patent/MX2011012738A/es active IP Right Grant
- 2010-06-04 ES ES15197076.1T patent/ES2692815T3/es active Active
- 2010-06-04 WO PCT/US2010/037542 patent/WO2010141918A1/en not_active Ceased
- 2010-06-04 CN CN201080028923.8A patent/CN102574902B/zh not_active Expired - Fee Related
- 2010-06-04 SI SI201031760T patent/SI3042915T1/sl unknown
- 2010-06-04 LT LTEP15197076.1T patent/LT3042915T/lt unknown
- 2010-06-04 US US12/794,132 patent/US9296800B2/en active Active
- 2010-06-04 PT PT15197076T patent/PT3042915T/pt unknown
- 2010-06-04 AU AU2010256426A patent/AU2010256426B2/en not_active Ceased
- 2010-06-04 DK DK10784210.6T patent/DK2438083T3/en active
- 2010-06-04 CA CA2764461A patent/CA2764461C/en active Active
- 2010-06-04 EP EP10784210.6A patent/EP2438083B1/en active Active
- 2010-06-04 HR HRP20160221T patent/HRP20160221T1/hr unknown
- 2010-06-04 JP JP2012514212A patent/JP5801293B2/ja not_active Expired - Fee Related
- 2010-06-04 SI SI201031135T patent/SI2438083T1/sl unknown
- 2010-06-04 TR TR2018/15592T patent/TR201815592T4/tr unknown
- 2010-06-04 ES ES10784210.6T patent/ES2563748T3/es active Active
- 2010-06-04 NZ NZ596849A patent/NZ596849A/xx not_active IP Right Cessation
- 2010-06-04 DK DK15197076.1T patent/DK3042915T3/en active
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2011
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- 2011-12-01 ZA ZA2011/08857A patent/ZA201108857B/en unknown
- 2011-12-01 IL IL216744A patent/IL216744A/en active IP Right Grant
- 2011-12-21 CO CO11176414A patent/CO6480917A2/es active IP Right Grant
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2015
- 2015-03-27 JP JP2015067656A patent/JP2015120754A/ja active Pending
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2017
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- 2017-04-20 US US15/492,085 patent/US20180044387A1/en not_active Abandoned
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2018
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2019
- 2019-12-31 US US16/731,320 patent/US20200369735A1/en not_active Abandoned
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2020
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2022
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