CR20120557A - Compuestos químicos - Google Patents

Compuestos químicos

Info

Publication number
CR20120557A
CR20120557A CR20120557A CR20120557A CR20120557A CR 20120557 A CR20120557 A CR 20120557A CR 20120557 A CR20120557 A CR 20120557A CR 20120557 A CR20120557 A CR 20120557A CR 20120557 A CR20120557 A CR 20120557A
Authority
CR
Costa Rica
Prior art keywords
chemical compounds
compounds
formula
treatment
disclosed
Prior art date
Application number
CR20120557A
Other languages
English (en)
Spanish (es)
Inventor
Christopher Joseph Aquino
Jon Loren Collins
David John Cowan
Yulin Wu
Original Assignee
Glaxosmithkline Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44861895&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR20120557(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxosmithkline Llc filed Critical Glaxosmithkline Llc
Publication of CR20120557A publication Critical patent/CR20120557A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D281/00Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02Seven-membered rings
    • C07D281/04Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/36Seven-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6536Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6536Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms
    • C07F9/6539Five-membered rings
    • C07F9/6541Five-membered rings condensed with carbocyclic rings or carbocyclic ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CR20120557A 2010-04-27 2012-11-01 Compuestos químicos CR20120557A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32821210P 2010-04-27 2010-04-27
US32922510P 2010-04-29 2010-04-29

Publications (1)

Publication Number Publication Date
CR20120557A true CR20120557A (es) 2013-02-20

Family

ID=44861895

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20120557A CR20120557A (es) 2010-04-27 2012-11-01 Compuestos químicos

Country Status (39)

Country Link
US (1) US9040518B2 (pl)
EP (1) EP2563122B1 (pl)
JP (1) JP5702853B2 (pl)
KR (1) KR101769079B1 (pl)
CN (1) CN102858159B (pl)
AR (1) AR081337A1 (pl)
AU (1) AU2011245393B2 (pl)
BR (1) BR112012026767B1 (pl)
CA (1) CA2795543C (pl)
CL (1) CL2012003009A1 (pl)
CO (1) CO6612267A2 (pl)
CR (1) CR20120557A (pl)
CY (1) CY1118187T1 (pl)
DK (1) DK2563122T3 (pl)
DO (1) DOP2012000263A (pl)
EA (1) EA021753B1 (pl)
ES (1) ES2588743T3 (pl)
HR (1) HRP20161103T1 (pl)
HU (1) HUE029480T2 (pl)
IL (1) IL222365A (pl)
JO (1) JO3131B1 (pl)
LT (1) LT2563122T (pl)
MA (1) MA34235B1 (pl)
ME (1) ME02490B (pl)
MX (1) MX2012012527A (pl)
MY (1) MY162933A (pl)
NZ (1) NZ602754A (pl)
PE (1) PE20130384A1 (pl)
PH (1) PH12012502128B1 (pl)
PL (1) PL2563122T3 (pl)
PT (1) PT2563122T (pl)
RS (1) RS55079B1 (pl)
SG (1) SG184812A1 (pl)
SI (1) SI2563122T1 (pl)
SM (1) SMT201600293B (pl)
UA (1) UA110338C2 (pl)
UY (1) UY33353A (pl)
WO (1) WO2011137135A1 (pl)
ZA (1) ZA201207858B (pl)

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JO3301B1 (ar) 2013-04-26 2018-09-16 Albireo Ab تعديلات بلورية على إيلوبيكسيبات
SG11201508469YA (en) 2013-05-02 2015-11-27 Glaxosmithkline Ip Dev Ltd Therapeutic peptides
CN106659726A (zh) 2014-06-25 2017-05-10 Ea制药株式会社 固体制剂及其着色防止或着色减少方法
JP6543330B2 (ja) * 2014-08-05 2019-07-10 グラクソスミスクライン、インテレクチュアル、プロパティー、(ナンバー2)、リミテッドGlaxosmithkline Intellectual Property (No.2) Limited ベンゾジアゼピンの合成
KR101674806B1 (ko) * 2014-10-20 2016-11-10 씨제이헬스케어 주식회사 신규한 아미노알킬벤조티아제핀 유도체 및 이의 용도
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EP3413878B1 (en) 2016-02-09 2021-04-14 Albireo AB Oral cholestyramine formulation and use thereof
EP3413875B1 (en) 2016-02-09 2020-01-29 Albireo AB Cholestyramine pellets and methods for preparation thereof
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JP2020530448A (ja) 2017-08-09 2020-10-22 アルビレオ・アクチボラグ コレスチラミン顆粒、経口コレスチラミン製剤、及びそれらの使用
JP7391048B2 (ja) 2018-06-05 2023-12-04 アルビレオ・アクチボラグ ベンゾチア(ジ)アゼピン化合物及び胆汁酸モジュレータとしてのそれらの使用
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US11801226B2 (en) 2018-06-20 2023-10-31 Albireo Ab Pharmaceutical formulation of odevixibat
US11549878B2 (en) 2018-08-09 2023-01-10 Albireo Ab In vitro method for determining the adsorbing capacity of an insoluble adsorbant
US11007142B2 (en) 2018-08-09 2021-05-18 Albireo Ab Oral cholestyramine formulation and use thereof
US10722457B2 (en) 2018-08-09 2020-07-28 Albireo Ab Oral cholestyramine formulation and use thereof
RS63899B1 (sr) 2019-02-06 2023-02-28 Albireo Ab Benzotiadiazepinska jedinjenja i njihova upotreba kao modulatora žučnih kiselina
TWI835997B (zh) 2019-02-06 2024-03-21 瑞典商艾爾比瑞歐公司 苯并噻氮呯化合物及其用作膽酸調節劑之用途
CA3129826A1 (en) 2019-02-12 2020-08-20 Mirum Pharmaceuticals, Inc. Methods for treating cholestasis
BR112022010505A2 (pt) 2019-12-04 2022-09-06 Albireo Ab Compostos de benzotia(di)azepina e seu uso como moduladores do ácido biliar
WO2021110886A1 (en) 2019-12-04 2021-06-10 Albireo Ab Benzothia(di)azepine compounds and their use as bile acid modulators
CA3158181A1 (en) 2019-12-04 2021-06-10 Albireo Ab Benzothia(di)azepine compounds and their use as bile acid modulators
EP4069359B1 (en) 2019-12-04 2024-01-03 Albireo AB Benzothia(di)azepine compounds and their use as bile acid modulators
JP7665620B2 (ja) 2019-12-04 2025-04-21 アルビレオ・アクチボラグ ベンゾチアジアゼピン化合物及び胆汁酸モジュレータとしてのそれらの使用
WO2021110887A1 (en) 2019-12-04 2021-06-10 Albireo Ab Benzothiazepine compounds and their use as bile acid modulators
TWI867107B (zh) * 2019-12-04 2024-12-21 瑞典商艾爾比瑞歐公司 苯并噻(二)氮呯化合物及其作為膽酸調節劑之用途
AR120679A1 (es) 2019-12-04 2022-03-09 Albireo Ab Compuestos de benzoti(di)azepina y su uso como moduladores ácido biliar
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US11014898B1 (en) 2020-12-04 2021-05-25 Albireo Ab Benzothiazepine compounds and their use as bile acid modulators
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EP4232043A1 (en) 2020-10-20 2023-08-30 GlaxoSmithKline Intellectual Property (No.2) Limited Methods for treating cholestatic pruritus
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TW202313579A (zh) 2021-06-03 2023-04-01 瑞典商艾爾比瑞歐公司 苯并噻(二)氮呯(benzothia(di)azepine)化合物及其作為膽酸調節劑之用途
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Also Published As

Publication number Publication date
SMT201600293B (it) 2016-11-10
PL2563122T3 (pl) 2016-12-30
EP2563122B1 (en) 2016-06-08
BR112012026767B1 (pt) 2020-01-21
MX2012012527A (es) 2012-12-17
PT2563122T (pt) 2016-09-01
AU2011245393B2 (en) 2014-01-23
RS55079B1 (sr) 2016-12-30
CN102858159A (zh) 2013-01-02
UA110338C2 (xx) 2015-12-25
HK1175650A1 (zh) 2013-07-12
ES2588743T3 (es) 2016-11-04
CN102858159B (zh) 2015-02-11
HUE029480T2 (en) 2017-02-28
ME02490B (me) 2017-02-20
CA2795543A1 (en) 2011-11-03
NZ602754A (en) 2014-05-30
UY33353A (es) 2011-12-01
MY162933A (en) 2017-07-31
KR20130060201A (ko) 2013-06-07
JO3131B1 (ar) 2017-09-20
EP2563122A1 (en) 2013-03-06
CY1118187T1 (el) 2017-06-28
JP5702853B2 (ja) 2015-04-15
PH12012502128A1 (en) 2013-02-04
KR101769079B1 (ko) 2017-08-30
DK2563122T3 (en) 2016-09-05
ZA201207858B (en) 2014-03-26
SI2563122T1 (sl) 2016-10-28
CA2795543C (en) 2017-11-28
US9040518B2 (en) 2015-05-26
CL2012003009A1 (es) 2013-03-08
EP2563122A4 (en) 2013-09-11
CO6612267A2 (es) 2013-02-01
WO2011137135A1 (en) 2011-11-03
IL222365A (en) 2016-03-31
JP2013525444A (ja) 2013-06-20
BR112012026767A2 (pt) 2015-09-29
IL222365A0 (en) 2012-12-31
HRP20161103T1 (hr) 2016-11-04
LT2563122T (lt) 2016-10-10
DOP2012000263A (es) 2013-09-15
SG184812A1 (en) 2012-11-29
AR081337A1 (es) 2012-08-08
PH12012502128B1 (en) 2017-11-08
US20130029938A1 (en) 2013-01-31
PE20130384A1 (es) 2013-04-04
EA021753B1 (ru) 2015-08-31
EA201290909A1 (ru) 2013-05-30
MA34235B1 (fr) 2013-05-02

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