CR20120608A - Nueva asociación entre la 4-{3-[cis-hexahidrociclopenta [c] pirrol-2(1h)-il]propoxi}benzamiday un antagonista de los receptores nmda y las composiciones farmacéuticas que la contienen - Google Patents

Nueva asociación entre la 4-{3-[cis-hexahidrociclopenta [c] pirrol-2(1h)-il]propoxi}benzamiday un antagonista de los receptores nmda y las composiciones farmacéuticas que la contienen

Info

Publication number
CR20120608A
CR20120608A CR20120608A CR20120608A CR20120608A CR 20120608 A CR20120608 A CR 20120608A CR 20120608 A CR20120608 A CR 20120608A CR 20120608 A CR20120608 A CR 20120608A CR 20120608 A CR20120608 A CR 20120608A
Authority
CR
Costa Rica
Prior art keywords
cis
antagonist
hexahydrociclopenta
benzamiday
propoxi
Prior art date
Application number
CR20120608A
Other languages
English (en)
Inventor
Aurore Sors
Caryn Trocme-Thibierge
Annette Merdes
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47682151&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR20120608(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Servier Lab filed Critical Servier Lab
Publication of CR20120608A publication Critical patent/CR20120608A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Asociación entre la 4-{3-[cis-hexahidrociclopenta[c]pirrol-2(1H) -il]propoxi}benzamida de fórmula (I) o una de sus sales de adición a un ácido o a una base farmacéuticamente aceptable, y un antagonista de los receptores glutamatérgicos NMDA.
CR20120608A 2011-12-09 2012-12-03 Nueva asociación entre la 4-{3-[cis-hexahidrociclopenta [c] pirrol-2(1h)-il]propoxi}benzamiday un antagonista de los receptores nmda y las composiciones farmacéuticas que la contienen CR20120608A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161568831P 2011-12-09 2011-12-09
FR1103777A FR2983732B1 (fr) 2011-12-09 2011-12-09 Nouvelle association entre le 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1h)-yl]propoxy}pharmaceutiques qui la contiennent

Publications (1)

Publication Number Publication Date
CR20120608A true CR20120608A (es) 2014-03-05

Family

ID=47682151

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20120608A CR20120608A (es) 2011-12-09 2012-12-03 Nueva asociación entre la 4-{3-[cis-hexahidrociclopenta [c] pirrol-2(1h)-il]propoxi}benzamiday un antagonista de los receptores nmda y las composiciones farmacéuticas que la contienen

Country Status (28)

Country Link
US (2) US8921409B2 (es)
EP (1) EP2601942A1 (es)
JP (1) JP5591310B2 (es)
KR (1) KR101489670B1 (es)
CN (1) CN103157111B (es)
AP (1) AP3225A (es)
AR (1) AR089112A1 (es)
AU (1) AU2012258339A1 (es)
BR (1) BR102012031031A2 (es)
CA (1) CA2798549A1 (es)
CL (1) CL2012003437A1 (es)
CO (2) CO6660080A1 (es)
CR (1) CR20120608A (es)
EA (1) EA201201530A1 (es)
EC (1) ECSP12012329A (es)
FR (1) FR2983732B1 (es)
GT (1) GT201200329A (es)
MA (1) MA34867B1 (es)
MD (1) MD4348B1 (es)
MX (1) MX2012014184A (es)
NI (1) NI201200178A (es)
PE (1) PE20130813A1 (es)
PH (1) PH12012000378A1 (es)
SG (1) SG191494A1 (es)
TN (1) TN2012000563A1 (es)
TW (1) TWI457123B (es)
UY (1) UY34475A (es)
WO (1) WO2013083887A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3003466B1 (fr) * 2013-03-22 2015-08-07 Servier Lab Utilisation du 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1h)-yl]propoxy}benzamide pour le traitement des douleurs neuropathiques
KR101484405B1 (ko) * 2013-08-14 2015-01-19 서울대학교산학협력단 Ｎｉｎｊｕｒｉｎ１ 결핍 유래의 강박증 예방 또는 치료용 약학적 조성물
GB201509134D0 (en) * 2015-05-28 2015-07-15 Electrophoretics Ltd Biomolecules involved in Alzheimer's disease
EP4484953A3 (en) * 2015-07-22 2025-03-12 Anavex Life Sciences Corp. Enantiomers of tetrahydro-n,n-dimethyl-2,2-diphenyl-3-furanmethanamine (anavex2-73) and use thereof in the treatment of alzheimer's disease and other disorders modulated by the sigma 1 receptor

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1509232B1 (en) * 2002-05-31 2008-11-19 H. Lundbeck A/S A combination of an nmda-antagonist and acetylcholine esterase inhibitors for the treatment of alzheimer's disease
MXPA05012493A (es) * 2003-05-27 2006-05-25 Forest Laboratories Combinacion de un antagonista del receptor de nmda y un inhibidor selectivo de reabsorcion de serotonina para el tratamiento de depresion y otros trastornos de estado de animo.
EP1638560A1 (en) * 2003-06-20 2006-03-29 Eli Lilly And Company 3-aminopiperidines and 3-aminoquinuclidines as inhibitors of monoamine uptake
AU2005204358B2 (en) * 2004-01-05 2008-09-04 Merz Pharma Gmbh & Co. Kgaa Memantine for the treatment of mild and mild-to-moderate Alzheimer's disease
FR2866647B1 (fr) * 2004-02-20 2006-10-27 Servier Lab Nouveaux derives azabicycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
TW200531680A (en) * 2004-03-03 2005-10-01 Merz Pharma Gmbh & Co Kgaa Therapy using 1-aminocyclohexane derivatives for the treatment of behavioral disorders associated with alzheimer's disease
US20070213388A1 (en) * 2004-03-19 2007-09-13 Bruinsma Gosse B Acetylcholinesterase Inhibitors and N-Methyl-D-Aspartate Antagonists Useful in the Treatment of of Cognitive Disorders
FR2937119B1 (fr) 2008-10-15 2010-12-17 Air Liquide Procede de production d'energie et capture de co2
FR2937251B1 (fr) * 2008-10-16 2011-03-18 Servier Lab Utilisation du 4-{3-°hexahydrocyclopenta°c!pyrrol-2(1h)-yl! propoxy}benzamide pour l'obtention de medicaments destines au traitement des troubles du sommeil
FR2953515B1 (fr) * 2009-12-09 2011-12-23 Servier Lab Nouveaux derives du type hexahydrocyclopenta[b]pyrrole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
NI201200178A (es) 2013-05-13
CA2798549A1 (fr) 2013-06-09
UY34475A (es) 2013-07-31
FR2983732B1 (fr) 2013-11-22
PH12012000378A1 (en) 2015-09-11
AP2012006607A0 (en) 2012-12-31
BR102012031031A2 (pt) 2013-10-29
US20130150421A1 (en) 2013-06-13
KR101489670B1 (ko) 2015-02-04
CO6690116A1 (es) 2013-06-17
EA201201530A1 (ru) 2013-07-30
JP5591310B2 (ja) 2014-09-17
AR089112A1 (es) 2014-07-30
CO6660080A1 (es) 2013-04-30
TW201334777A (zh) 2013-09-01
AU2012258339A1 (en) 2013-06-27
AP3225A (en) 2015-04-30
SG191494A1 (en) 2013-07-31
WO2013083887A1 (fr) 2013-06-13
US8921409B2 (en) 2014-12-30
FR2983732A1 (fr) 2013-06-14
CL2012003437A1 (es) 2014-01-24
CN103157111A (zh) 2013-06-19
MX2012014184A (es) 2013-06-18
TWI457123B (zh) 2014-10-21
MD4348B1 (ro) 2015-05-31
JP2013121956A (ja) 2013-06-20
KR20130065602A (ko) 2013-06-19
PE20130813A1 (es) 2013-07-28
ECSP12012329A (es) 2013-01-31
EP2601942A1 (fr) 2013-06-12
TN2012000563A1 (fr) 2014-04-01
US20150080448A1 (en) 2015-03-19
WO2013083887A8 (fr) 2013-08-08
NZ604084A (en) 2014-07-25
MA34867B1 (fr) 2014-02-01
GT201200329A (es) 2014-03-14
CN103157111B (zh) 2015-02-11

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