CR20130500A - Moduladores de los receptores de hormonas nucleares - Google Patents

Moduladores de los receptores de hormonas nucleares

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Publication number
CR20130500A
CR20130500A CR20130500A CR20130500A CR20130500A CR 20130500 A CR20130500 A CR 20130500A CR 20130500 A CR20130500 A CR 20130500A CR 20130500 A CR20130500 A CR 20130500A CR 20130500 A CR20130500 A CR 20130500A
Authority
CR
Costa Rica
Prior art keywords
modulators
hormone receptors
nuclear hormone
prodrugs
stereoisomers
Prior art date
Application number
CR20130500A
Other languages
English (en)
Inventor
Kevin P Cusack
Thomas D Gordon
David C Ihle
Martin E Hayes
Eric C Breinlinger
Anna M Ericsson
Bin Li
Lei Wang
Gloria Y Martinez
Andrew Burchat
Adrian D Hobson
Kelly D Mullen
Michael Friedman
Michael J Morytko
Original Assignee
Abbvie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46828945&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR20130500(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbvie Inc filed Critical Abbvie Inc
Publication of CR20130500A publication Critical patent/CR20130500A/es

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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
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Abstract

Un compuesto de fórmula (I) sales, prodrogas, metabolitos biológicamente activos, estereoisómeros e isómeros farmacéuticamente aceptables del mismo, en donde las variables se definieron en la presente. Los compuestos de la invención son de utilidad para el tratamiento de condiciones inmunológicas y oncológicas.
CR20130500A 2011-03-15 2013-09-30 Moduladores de los receptores de hormonas nucleares CR20130500A (es)

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MX391135B (es) 2016-06-24 2025-03-21 Infinity Pharmaceuticals Inc Terapias de combinacion.
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