CR20130501A - Derivados novedosos de cefalosporinas y composiciones farmacéuticas de estos - Google Patents

Derivados novedosos de cefalosporinas y composiciones farmacéuticas de estos

Info

Publication number
CR20130501A
CR20130501A CR20130501A CR20130501A CR20130501A CR 20130501 A CR20130501 A CR 20130501A CR 20130501 A CR20130501 A CR 20130501A CR 20130501 A CR20130501 A CR 20130501A CR 20130501 A CR20130501 A CR 20130501A
Authority
CR
Costa Rica
Prior art keywords
cephalosporins
derivatives
novedous
pharmaceutical compositions
relates
Prior art date
Application number
CR20130501A
Other languages
English (en)
Inventor
Young L Cho
Joung Yul Yun
Chul Soon Park
Sang Eun Chae
Hyang Sook Lee
Kyuman Oh
Hye Jin Heo
Dae Hyuck Kang
Young Jae Yang
Hyun Jin Kwon
Tae Kyo Park
Sung Ho Woo
Yong Zu Kim
Original Assignee
Legochem Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Legochem Biosciences Inc filed Critical Legochem Biosciences Inc
Publication of CR20130501A publication Critical patent/CR20130501A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/60—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 3 and 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

La presente invención se refiere a derivados novedosos de cefalosporinas representados por la fórmula química 1.
CR20130501A 2011-03-30 2013-09-30 Derivados novedosos de cefalosporinas y composiciones farmacéuticas de estos CR20130501A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020110028603A KR101719556B1 (ko) 2011-03-30 2011-03-30 신규한 세파로스포린 유도체 및 이를 함유하는 의약 조성물

Publications (1)

Publication Number Publication Date
CR20130501A true CR20130501A (es) 2014-05-13

Family

ID=46932135

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20130501A CR20130501A (es) 2011-03-30 2013-09-30 Derivados novedosos de cefalosporinas y composiciones farmacéuticas de estos

Country Status (28)

Country Link
US (2) US8329684B2 (es)
EP (1) EP2706062B1 (es)
JP (1) JP6144669B2 (es)
KR (1) KR101719556B1 (es)
CN (1) CN103547583B (es)
AU (1) AU2012237063B2 (es)
BR (1) BR112013025275A2 (es)
CA (1) CA2831421C (es)
CL (1) CL2013002820A1 (es)
CO (1) CO6821935A2 (es)
CR (1) CR20130501A (es)
CU (1) CU20130125A7 (es)
DK (1) DK2706062T3 (es)
DO (1) DOP2013000214A (es)
EA (1) EA024709B1 (es)
ES (1) ES2683351T3 (es)
HR (1) HRP20181170T1 (es)
HU (1) HUE039086T2 (es)
IL (1) IL228408A (es)
LT (1) LT2706062T (es)
MX (1) MX359435B (es)
PH (1) PH12013501950A1 (es)
PL (1) PL2706062T3 (es)
PT (1) PT2706062T (es)
SG (1) SG193998A1 (es)
SI (1) SI2706062T1 (es)
WO (1) WO2012134184A2 (es)
ZA (1) ZA201308078B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009049086A1 (en) 2007-10-09 2009-04-16 Larry Sutton Broad spectrum beta-lactamase inhibitors
CA2961489A1 (en) 2014-09-17 2016-03-24 Glen Robert RENNIE Sgc stimulators
US10059680B2 (en) * 2014-12-18 2018-08-28 Merck Sharp & Dohme Corp. Thiadiazolyl-oximinoacetic acid derivative compounds
US20160176897A1 (en) 2014-12-23 2016-06-23 Merck Sharp & Dohme Corp. 7-aminocephem derivative compounds
WO2017096472A1 (en) 2015-12-10 2017-06-15 Naeja-Rgm Pharmaceuticals Inc. Cephem compounds, their production and use
CN109843896B (zh) * 2016-10-14 2022-12-20 波尔图大学 羟基肉桂酸衍生物、方法及其用途
KR20180093307A (ko) * 2017-02-13 2018-08-22 주식회사 레고켐 바이오사이언스 4, 5-디아미노 치환 피리미딘 유도체의 제조방법 및 이를 제조하기 위한 신규한 화합물
WO2019145784A2 (en) * 2018-01-26 2019-08-01 Legochem Biosciences, Inc. Combination therapies for multi-drug resistant pathogens
CN109762791B (zh) * 2018-11-19 2021-02-09 厦门联合安金生物工程有限公司 包含BPI-Fc嵌合基因的重组腺病毒及其用途
CN111471058A (zh) * 2019-01-23 2020-07-31 中国医学科学院药物研究所 用于制备头孢吡普类似物的方法
US12371441B2 (en) 2019-09-06 2025-07-29 Ariva Med Gmbh Siderophore cephalosporin conjugates and uses thereof
CN111635377A (zh) * 2020-06-30 2020-09-08 南京红杉生物科技有限公司 噻二唑类化合物及其合成方法
WO2022235077A1 (ko) * 2021-05-07 2022-11-10 한국생명공학연구원 신규 사이드로포어 화합물 및 이를 이용한 금속 나노입자 복합체
US12225906B1 (en) 2024-09-26 2025-02-18 Terry Earl Brady Pathogenic affinity pathway of infectious or parasitic organisms for nanogram and picogram dosimetry prophylaxis or cure

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3006888A1 (de) * 1980-02-23 1981-09-10 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
EP0303172A3 (de) * 1987-08-14 1991-05-15 F. Hoffmann-La Roche Ag Oxyimino-Cephalosporine
GB8817653D0 (en) * 1988-07-25 1988-09-01 Fujisawa Pharmaceutical Co New cephem compounds & processes for preparation thereof
GB9111406D0 (en) * 1991-05-28 1991-07-17 Fujisawa Pharmaceutical Co New cephem compounds and processes for preparation thereof
US5498777A (en) * 1994-07-20 1996-03-12 Merck & Co., Inc. 3-thioheteroaryl cephalosporin compounds, compositions and methods of use
TW200305422A (en) * 2002-03-18 2003-11-01 Shionogi & Co Broad spectrum cefem compounds
ATE388153T1 (de) * 2003-07-11 2008-03-15 Theravance Inc Quervernetzte glycopeptid-cephalosporin- antibiotika
CN1922190A (zh) * 2004-03-05 2007-02-28 盐野义制药株式会社 3－吡啶甲基头胞化合物
AU2005202802A1 (en) * 2004-06-28 2006-01-12 Astellas Pharma Inc. Cephem compounds
CN101230070A (zh) * 2006-12-30 2008-07-30 黄振华 新型抗感染头孢类化合物
MX2011004636A (es) * 2008-10-31 2011-06-20 Shionogi & Co Cefarosporinas que tienen un grupo catecol.

Also Published As

Publication number Publication date
US20130178455A1 (en) 2013-07-11
KR101719556B1 (ko) 2017-03-24
EP2706062A4 (en) 2015-01-21
JP6144669B2 (ja) 2017-06-07
EP2706062B1 (en) 2018-05-09
WO2012134184A8 (ko) 2013-10-24
ES2683351T3 (es) 2018-09-26
IL228408A (en) 2017-01-31
LT2706062T (lt) 2018-10-25
CN103547583A (zh) 2014-01-29
CN103547583B (zh) 2016-11-16
CA2831421C (en) 2019-06-04
DOP2013000214A (es) 2013-12-15
BR112013025275A2 (pt) 2016-12-13
AU2012237063A1 (en) 2013-10-17
ZA201308078B (en) 2019-01-30
HUE039086T2 (hu) 2018-12-28
EA201391325A1 (ru) 2014-04-30
DK2706062T3 (en) 2018-08-06
CO6821935A2 (es) 2013-12-31
EA024709B1 (ru) 2016-10-31
CU20130125A7 (es) 2014-03-26
HRP20181170T1 (hr) 2018-11-02
WO2012134184A2 (ko) 2012-10-04
JP2014510750A (ja) 2014-05-01
AU2012237063B2 (en) 2017-03-16
US8329684B2 (en) 2012-12-11
US9630977B2 (en) 2017-04-25
SG193998A1 (en) 2013-11-29
MX359435B (es) 2018-09-28
KR20120110625A (ko) 2012-10-10
PH12013501950A1 (en) 2013-11-25
MX2013010961A (es) 2014-03-27
EP2706062A2 (en) 2014-03-12
CL2013002820A1 (es) 2014-04-11
CA2831421A1 (en) 2012-10-04
SI2706062T1 (sl) 2018-11-30
US20120264727A1 (en) 2012-10-18
IL228408A0 (en) 2013-12-31
PL2706062T3 (pl) 2018-11-30
WO2012134184A3 (ko) 2013-03-07
PT2706062T (pt) 2018-09-28

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal (granting procedure)