CR20150386A - Composiciones de nanoparticulas de albumina y paclitaxel - Google Patents

Composiciones de nanoparticulas de albumina y paclitaxel

Info

Publication number
CR20150386A
CR20150386A CR20150386A CR20150386A CR20150386A CR 20150386 A CR20150386 A CR 20150386A CR 20150386 A CR20150386 A CR 20150386A CR 20150386 A CR20150386 A CR 20150386A CR 20150386 A CR20150386 A CR 20150386A
Authority
CR
Costa Rica
Prior art keywords
compositions
albumin
paclitaxel nanoparticles
paclitaxel
nanoparticles
Prior art date
Application number
CR20150386A
Other languages
English (en)
Inventor
Neil P Desai
Original Assignee
Abraxis Bioscience Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abraxis Bioscience Llc filed Critical Abraxis Bioscience Llc
Publication of CR20150386A publication Critical patent/CR20150386A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5169—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

La invención proporciona composiciones (tales como composiciones farmacéuticas) que comprenden nanopartículas albúmina y paclitaxel. Las composiciones tienen un perfil específico de polímero/monómero de albúmina y son particularmente adecuadas para uso en el tratamiento de enfermedades tales como cáncer.
CR20150386A 2012-12-28 2015-07-22 Composiciones de nanoparticulas de albumina y paclitaxel CR20150386A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261747123P 2012-12-28 2012-12-28
US13/794,705 US20140186447A1 (en) 2012-12-28 2013-03-11 Nanoparticle compositions of albumin and paclitaxel
PCT/US2013/076630 WO2014105644A1 (en) 2012-12-28 2013-12-19 Nanoparticle compositions of albumin and paclitaxel

Publications (1)

Publication Number Publication Date
CR20150386A true CR20150386A (es) 2015-10-07

Family

ID=51017455

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20150386A CR20150386A (es) 2012-12-28 2015-07-22 Composiciones de nanoparticulas de albumina y paclitaxel

Country Status (19)

Country Link
US (2) US20140186447A1 (es)
EP (1) EP2938340A4 (es)
JP (2) JP2016504362A (es)
KR (1) KR20150100903A (es)
CN (1) CN105007912A (es)
AU (1) AU2013370955B2 (es)
BR (1) BR112015015319A2 (es)
CA (1) CA2896288A1 (es)
CR (1) CR20150386A (es)
HK (1) HK1216611A1 (es)
IL (1) IL239593A0 (es)
MX (1) MX2015008361A (es)
NI (1) NI201500090A (es)
NZ (1) NZ630912A (es)
PH (1) PH12015501486B1 (es)
RU (1) RU2663687C2 (es)
SG (1) SG11201505111TA (es)
WO (1) WO2014105644A1 (es)
ZA (1) ZA201504762B (es)

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CN104224750A (zh) * 2014-09-17 2014-12-24 四川大学 一种注射用卡巴他赛白蛋白纳米粒制剂及其制备方法
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UA123665C2 (uk) 2014-11-25 2021-05-12 Кюрадігм Сас Фармацевтична композиція, її одержання і застосування
EP3229776B1 (en) 2014-11-25 2023-06-28 Curadigm Sas Pharmaceutical composition combining at least two distinct nanoparticles and a pharmaceutical compound, preparation and uses thereof
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US10527604B1 (en) 2015-03-05 2020-01-07 Abraxis Bioscience, Llc Methods of assessing suitability of use of pharmaceutical compositions of albumin and paclitaxel
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Also Published As

Publication number Publication date
AU2013370955A1 (en) 2015-07-16
SG11201505111TA (en) 2015-07-30
US20190192477A1 (en) 2019-06-27
HK1216611A1 (zh) 2016-11-25
NI201500090A (es) 2015-12-22
JP2016504362A (ja) 2016-02-12
IL239593A0 (en) 2015-08-31
ZA201504762B (en) 2016-10-26
CN105007912A (zh) 2015-10-28
PH12015501486A1 (en) 2015-09-21
PH12015501486B1 (en) 2020-12-16
JP2018087241A (ja) 2018-06-07
AU2013370955B2 (en) 2018-12-06
BR112015015319A2 (pt) 2017-07-11
US20140186447A1 (en) 2014-07-03
RU2015131141A (ru) 2017-02-03
MX2015008361A (es) 2016-03-11
NZ630912A (en) 2017-05-26
RU2663687C2 (ru) 2018-08-08
WO2014105644A1 (en) 2014-07-03
KR20150100903A (ko) 2015-09-02
EP2938340A4 (en) 2016-08-03
EP2938340A1 (en) 2015-11-04
CA2896288A1 (en) 2014-07-03

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