CR20170134A - Método para preparar 2´-o-fucosil-lactosa - Google Patents
Método para preparar 2´-o-fucosil-lactosaInfo
- Publication number
- CR20170134A CR20170134A CR20170134A CR20170134A CR20170134A CR 20170134 A CR20170134 A CR 20170134A CR 20170134 A CR20170134 A CR 20170134A CR 20170134 A CR20170134 A CR 20170134A CR 20170134 A CR20170134 A CR 20170134A
- Authority
- CR
- Costa Rica
- Prior art keywords
- lactose
- preparing
- fucosil
- fucosyl
- formula
- Prior art date
Links
- 239000008101 lactose Substances 0.000 title 1
- HWHQUWQCBPAQQH-BWRPKUOHSA-N 2-fucosyllactose Chemical compound O[C@H]1[C@H](O)[C@H](O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@H]([C@H](O)CO)[C@H](O)[C@@H](O)C=O HWHQUWQCBPAQQH-BWRPKUOHSA-N 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000008267 fucoses Chemical class 0.000 abstract 1
- IDIOJRGTRFRIJL-UHFFFAOYSA-N iodosilane Chemical compound I[SiH3] IDIOJRGTRFRIJL-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- General Preparation And Processing Of Foods (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
La presente invención se refiere a un método para preparar 2'-O-fucosil-lactosa, a la 2'-O-fucosil-lactosa obtenible por este método y a su uso. El método comprende hacer reaccionar los derivados de fucosa protegidos persililados de la fórmula (I) de abajo, con al menos un yoduro de tri(alquil C1-C6)sililo y posteriormente hacer reaccionar el producto así obtenido con el compuesto de la fórmula general (II), en presencia de una base.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14184606 | 2014-09-12 | ||
| PCT/EP2015/070844 WO2016038192A1 (en) | 2014-09-12 | 2015-09-11 | Method for preparing 2'-o-fucosyllactose |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CR20170134A true CR20170134A (es) | 2017-06-13 |
Family
ID=51687775
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CR20170134A CR20170134A (es) | 2014-09-12 | 2015-09-11 | Método para preparar 2´-o-fucosil-lactosa |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US11098075B2 (es) |
| EP (1) | EP3191498B1 (es) |
| JP (1) | JP6637492B2 (es) |
| KR (1) | KR20170052631A (es) |
| CN (1) | CN106795193B (es) |
| AU (1) | AU2015314165B2 (es) |
| BR (1) | BR112017004667A2 (es) |
| CA (1) | CA2960056A1 (es) |
| CR (1) | CR20170134A (es) |
| DK (1) | DK3191498T3 (es) |
| HU (1) | HUE051855T2 (es) |
| IL (1) | IL250682A0 (es) |
| MX (1) | MX2017003238A (es) |
| WO (1) | WO2016038192A1 (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2017137403A (ru) | 2015-03-26 | 2019-04-26 | Басф Се | Биокаталитическое получение l-фукозы |
| MX2017014148A (es) | 2015-05-04 | 2018-03-15 | Basf Se | Proceso para la preparacion de melonal. |
| CN108602845A (zh) * | 2016-02-03 | 2018-09-28 | 巴斯夫欧洲公司 | 生产2’-o-岩藻糖基乳糖的方法 |
| US10954538B2 (en) | 2016-02-19 | 2021-03-23 | Basf Se | Enzymatic cyclization of homofarnesylic acid |
| WO2017211784A1 (en) | 2016-06-07 | 2017-12-14 | Basf Se | Process for preparing 2,3-unsaturated alcohols |
| JP7039498B2 (ja) | 2016-06-29 | 2022-03-22 | ビーエーエスエフ ソシエタス・ヨーロピア | 液相の存在下でのアルコールの酸化によるアルファ，ベータ不飽和アルデヒドの製造方法 |
| EP3506768B8 (en) * | 2016-08-31 | 2026-02-25 | OligoScience Biotechnology GmbH | Milk replacer composition comprising 2'-fucosyllactose for use in the treatment or prevention of gastro-intestinal diseases of production animals |
| EP3867258A1 (en) | 2018-10-18 | 2021-08-25 | Basf Se | Method for obtaining crystalline 2'-fucosyllactose |
| KR20220154158A (ko) | 2020-03-12 | 2022-11-21 | 글리콤 에이/에스 | 2'-fl의 결정화 |
| WO2024038195A1 (en) * | 2022-08-19 | 2024-02-22 | Dsm Ip Assets B.V. | Synthesis of hmo propionate |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5438124A (en) | 1991-07-16 | 1995-08-01 | Health Research, Inc. | Glycosylating reagent for the synthesis of linear and other α-L-fucosyl oligosaccharides |
| IT1392456B1 (it) | 2008-12-18 | 2012-03-09 | Inalco Spa | Processo per la sintesi di di- o oligosaccaridi l-fucosilati e loro nuovi intermedi 2,3,4-tribenzil-fucosil-derivati. |
| CA2758097A1 (en) | 2009-04-07 | 2010-10-14 | Glycom A/S | Synthesis of 2'-o-fucosyllactose |
| CN103429604A (zh) | 2011-02-21 | 2013-12-04 | 格礼卡姆股份公司 | 寡糖前体的混合物的组合物的催化氢解及其用途 |
| EP2707379A4 (en) * | 2011-05-13 | 2014-10-08 | Glycosyn LLC | USE OF PURIFIED 2'-FUCOSYLLACTOSIS, 3-FUCOSYLLACTOSIS AND LACTODIFUCOTETRAOSE AS PREBIOTICS |
| GB201111263D0 (en) | 2011-07-01 | 2011-08-17 | Nat Univ Ireland | Multivalent oligosaccharides |
| WO2013048294A1 (en) | 2011-09-30 | 2013-04-04 | Volvo Technology Corporation | Exhaust gas after treatment system comprising multiple catalytic objects |
-
2015
- 2015-09-11 DK DK15763307.4T patent/DK3191498T3/da active
- 2015-09-11 JP JP2017513743A patent/JP6637492B2/ja active Active
- 2015-09-11 EP EP15763307.4A patent/EP3191498B1/en active Active
- 2015-09-11 WO PCT/EP2015/070844 patent/WO2016038192A1/en not_active Ceased
- 2015-09-11 US US15/510,268 patent/US11098075B2/en active Active
- 2015-09-11 KR KR1020177009260A patent/KR20170052631A/ko not_active Withdrawn
- 2015-09-11 CA CA2960056A patent/CA2960056A1/en not_active Abandoned
- 2015-09-11 MX MX2017003238A patent/MX2017003238A/es unknown
- 2015-09-11 HU HUE15763307A patent/HUE051855T2/hu unknown
- 2015-09-11 AU AU2015314165A patent/AU2015314165B2/en not_active Ceased
- 2015-09-11 BR BR112017004667A patent/BR112017004667A2/pt not_active IP Right Cessation
- 2015-09-11 CR CR20170134A patent/CR20170134A/es unknown
- 2015-09-11 CN CN201580048101.9A patent/CN106795193B/zh active Active
-
2017
- 2017-02-20 IL IL250682A patent/IL250682A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2017534575A (ja) | 2017-11-24 |
| MX2017003238A (es) | 2017-06-29 |
| JP6637492B2 (ja) | 2020-01-29 |
| DK3191498T3 (da) | 2020-12-21 |
| AU2015314165B2 (en) | 2019-06-06 |
| CN106795193B (zh) | 2021-02-26 |
| EP3191498B1 (en) | 2020-09-30 |
| CA2960056A1 (en) | 2016-03-17 |
| CN106795193A (zh) | 2017-05-31 |
| IL250682A0 (en) | 2017-04-30 |
| BR112017004667A2 (pt) | 2018-01-30 |
| AU2015314165A1 (en) | 2017-03-16 |
| HUE051855T2 (hu) | 2021-03-29 |
| US20180230176A1 (en) | 2018-08-16 |
| EP3191498A1 (en) | 2017-07-19 |
| US11098075B2 (en) | 2021-08-24 |
| WO2016038192A1 (en) | 2016-03-17 |
| KR20170052631A (ko) | 2017-05-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1125610T1 (el) | Παραγωγο κινολινης υψηλης καθαροτητας και μεθοδος για την παρασκευη του | |
| CY1124097T1 (el) | Κρυσταλλικο πολυμορφο της ελευθερης βασης της 2-υδροξυ-6-((2-(1-ισοπροπυλο-1η-πυραζολ-5-υλο)πυριδιν-3-υλο)μεθοξυ)βενζαλδεϋδης | |
| DOP2016000299A (es) | Derivados de pirrolidina-2,5-diona, composiciones farmacéuticas y su uso como inhibidores ido1 | |
| PH12018502535B1 (en) | Substituted carbonucleoside derivatives useful as anticancer agents | |
| GT201400297A (es) | Nuevos derivados tienopirimidina, un proceso para su preparación y composiciones farmacéuticas que los contienen | |
| DOP2015000270A (es) | Potenciador de inhibidores del homólogo de zeste | |
| ECSP14000074A (es) | Mètodos para preparar anàlogos nucleotìdicos antivirales | |
| PH12016500169A1 (en) | Polymorph of syk inhibitors | |
| EA201992183A3 (ru) | Синтез полициклических карбамоилпиридоновых соединений | |
| TW201613603A (en) | Pharmaceutical preparation | |
| MX2017003238A (es) | Metodo para preparar 2'-o-fucosil-lactosa. | |
| MX390748B (es) | Composiciones y metodos para tratar accidente cerebrovascular isquemico. | |
| GT201500235A (es) | Estra -1,3,5 (10) , 16- tetraeno -3-carboxamidas para la inhibicion de la 17b-hidroxiesteroide deshidrogenasa (akr1c3) | |
| UY36746A (es) | Método para la síntesis de derivados de rapamicina | |
| MX388612B (es) | Intermediarios para preparar herbicidas de piridazinona y proceso para prepararlos. | |
| CY1121484T1 (el) | Μορφες αλατος και κρυσταλλου ενος αναστολεα plk-4 | |
| CY1125355T1 (el) | Πεντακυκλικη ενωση | |
| EP4001266A3 (en) | Process for preparing methoxy methyl pyridine dicarboxylate | |
| ES2603227T3 (es) | Proceso para la preparación de compuestos cetólidos | |
| WO2016190501A8 (ko) | 유기 광전자 소자용 화합물, 유기 광전자 소자용 조성물, 및 이를 포함하는 유기 광전자 소자 및 표시장치 | |
| MY185971A (en) | Pyranodipyridine compound | |
| WO2015155453A3 (fr) | Nouveaux composes organo-selenies, procédé de fabrication et applications en pharmacie notamment comme agents anti-tumoraux | |
| SV2016005310A (es) | Derivados de diheterociclo enlazado a cicloalquilo | |
| BR112018006005A2 (pt) | composto bicíclico e uso do mesmo para inibição de suv39h2 | |
| MX2017002015A (es) | Ligando del receptor 2 de canabinoide radiomarcado. |